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Fuzzy optimization design of multicomponent refinery hydrogen network

Chinese Journal of Chemical Engineering 2022年第8期35卷 125-139页

作者： Chun Deng Xuantong Lu Qixin Zhang Jian Liu jui-yuan lee Xiao Feng State Key Laboratory of Heavy Oil Processing College of Chemical Engineering and EnvironmentChina University of PetroleumBeijing 102249China PetroChina Daqing Petrochemical Company Daqing 163000China Department of Chemical Engineering and Biotechnology National Taipei University of TechnologyTaipei 10608China School of Chemical Engineering&Technology Xi’an Jiaotong UniversityXi’an 710049China

Hydrogen and light hydrocarbon components are essential resources of the refinery.The optimization of the refinery hydrogen system and recovery of the light hydrocarbon components contained in the gas streams are key strategies to reduce the operating costs for sustainable development.Many research efforts have been focused on the optimization of single impurity hydrogen network,and the flowrates of the hydrogen sources and sinks are assumed to be constant.However,their flowrates vary along with the quality of crude oil and refinery processing plans.A general superstructure of multicomponent refinery hydrogen network is proposed,which considers four components,namely H_(2),H_(2)S,CH_(4) and C_(2+),as well as the flowrate variations of hydrogen source and hydrogen sink.The mathematical model based on the superstructure is developed with objective functions,including the minimization of total annualized cost and the maximization of overall satisfaction of the hydrogen network.Moreover,the model considers the removal of hydrogen sulfide and the recovery of light hydrocarbon components(i.e.,C_(2+))in the optimization.To verify the applicability of the proposed mathematical model,a simplified industrial case study with four scenarios is solved.The optimization results show that the economic benefit can be maximized by considering both the direct reuse of gas streams from high-pressure separator(HP gas stream)and from low-pressure separator(LP gas stream)and the recovery of the light hydrocarbon streams.The fuzzy optimization method can be used to guide the optimal design of the refinery hydrogen system with multi-period variable flowrates.

关键词： Hydrogen network Mathematical programming Multicomponent Fuzzy optimization Light hydrocarbon recovery

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A novel AIE-NIR-II nano-contrast agent for monitoring and evaluating kidney transplant

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National Science Review 2024年第4期11卷 15-16页

作者： yuan-yuan Zhao Bokyeong Hwang Yeju lee Juyoung Yoon Department of Chemistry and Nanoscience Ewha Womans University

Kidney transplantation is a life-saving approach for treating end-stage renal diseases (ESRDs)[1]. However, the scarcity of donor kidneys has resulted in an increasing number of ESRD patients being stuck on the transp... 详细信息

关键词： TIME

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Population Dynamics in an Advective Environment

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Communications on Applied Mathematics and Computation 2024年第1期6卷 399-430页

作者： King-Yeung Lam Ray lee yuan Lou Department of Mathematics The Ohio State UniversityColumbusOH43210USA School of Mathematical Sciences CMA-Shanghai and MOE-LSCShanghai Jiao Tong UniversityShanghai200240China

We consider a one-dimensional reaction-diffusion equation describing single-and two-species population dynamics in an advective environment,based on the modeling frameworks proposed by Lutscher et al.in 2006.We analyze the effect of rate of loss of individuals at both the upstream and downstream boundaries.In the single-species case,we prove the existence of the critical domain size and provide explicit formulas in terms of model parameters.We further derive qualitative properties of the critical domain size and show that,in some cases,the critical domain size is either strictly decreasing over all diffusion rates,or monotonically increasing after first decreasing to a minimum.We also consider competition between species differing only in their diffusion rates.For two species having large diffusion rates,we give a sufficient condition to determine whether the faster or slower diffuser wins the competition.We also briefly discuss applications of these results to competition in species whose spatial niche is affected by shifting isotherms caused by climate change.

关键词： Reaction-diffusion-advection Critical domain size Competition Climate change

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Characterization of a smog chamber for studying formation of gas-phase products and secondary organic aerosol

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Journal of Environmental Sciences 2024年第2期136卷 570-582页

作者： Qi yuan Zhuozhi Zhang Meng Wang Kin Fai Ho Tao Wang Shuncheng lee Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityKowloonHong KongChina School of Public Health and Primary Care The Chinese University of Hong KongShatinHong KongChina

Smog chambers provide a potent approach to explore the secondary organic aerosol formation under varied conditions.This study describes the construction and characterization of a new smog chamber facility for studying the formation mechanisms of gas-phase products and secondary organic aerosol from the photooxidation of volatile organic compounds.The chamber is a 5.4 m^(3) Fluorinated Ethylene Propylene(FEP)Teflon reactor with the potential to perform photooxidation experiments at controlled temperature and relative humidity.Detailed characterizations were conducted for evaluation of stability of environmental parameters,mixing time,background contamination,light intensity,and wall losses of gases and particles.The photolysis rate of NO_(2)(J_(NO2))ranged from(1.02-3.32)×10^(-3)sec^(-1),comparable to the average J_(NO2)in ambient environment.The wall loss rates for NO,NO_(2),and O_(3)were 0.47×10^(-4),0.37×10^(-4),and 1.17×10^(-4)min^(-1),while wall loss of toluene was obsoletely found in a 6 hr test.The particle number wall loss rates are(0.01-2.46)×10^(-3)min^(-1)for 40-350 nm with an average lifetime of more than one day.A series of toluene photooxidation experiments were carried out in absence of NO_xunder dry conditions.The results of the simulation experiments demonstrated that the chamber is well designed to simulate photolysis progress in the atmosphere.

关键词： Smog chamber Gas-phase oxidation Chamber characterization Chemical mechanism

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Small intestine angioleiomyoma as a rare cause of perforation:A case report

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World Journal of Clinical Cases 2024年第12期12卷 2116-2121页

作者： Teng-yuan Hou Wei-Juo Tzeng Pei-Hang lee Department of General Surgery Kaohsiung Chang Gung Memorial HospitalKaohsiung 833Taiwan Department of Anatomical Pathology Kaohsiung Chang Gung Memorial HospitalKaohsiung 833Taiwan

BACKGROUND Angioleiomyoma is a rare and benign stromal tumor typically found in subcutaneous tissue.It rarely occurs in the gastrointestinal tract.Among the reported cases,the most common complication was gastrointestinal bleeding.Perforation has only been reported as a complication in the last few decades.CASE SUMMARY This case report detailed the discovery of intestinal angioleiomyoma in a 47-yearold male presenting with abdominal pain that had persisted for 3 d.After suspecting hollow organ perforation,surgical intervention involving intestinal resection and anastomosis was performed.CONCLUSION The report underscores the significance of early surgical intervention in effectively treating angioleiomyoma while emphasizing the pivotal role of timely and appropriate measures for favorable outcomes.

关键词： Angioleiomyoma Intestinal perforation Abdomen Acute Diarrhea Case report

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Nano-revolution in hepatocellular carcinoma:A multidisciplinary odyssey-Are we there yet?

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World Journal of Hepatology 2024年第5期16卷 684-687页

作者： Howard D lee Li-Yun yuan Department of Medicine Division of Gastrointestinal and Liver DiseasesKeck School of Medicine of University of Southern CaliforniaLos AngelesCA 90033United States

In this editorial we comment on the review by Zhou et al reviewing the landscape of nanomedicine in the treatment of hepatocellular carcinoma(HCC).We focus on the immense potential of nanotechnology,particularly ligand-receptor mediated nanotherapy,in revolutionizing the treatment landscape of HCC.Despite advan-cements in multidisciplinary treatment,HCC remains a significant global health challenge.Ligand-mediated nanotherapy offers the opportunity for precise drug delivery to tumor sites,targeting specific receptors overexpressed in HCC cells,thereby enhancing efficacy and minimizing side effects.Overcoming drug resistance and aggressive tumor biology is facilitated by nanomedicine,bypassing traditional hurdles encountered in chemotherapy.Examples include targeting glypican-3,asialoglycoprotein,transferrin receptor or folic acid receptors,capitalizing on their over-expression in tumor cells.The ability for multi-receptor targeting through dual-ligand nanoparticle modification holds the prospect of further enhancement in specificity and efficacy of directed therapy.However,challenges including immune responses,reproducibility in nanoparticle synthesis,and production scalability remain.Future directions involve refining targeting strategies,improving drug release mechanisms,and streamlining production processes to enable personalized and multifunctional nanotherapies.Overall,the integration of nanotherapy in HCC treatment holds immense promise,but continued partnership and effort are needed in offering hope for more effective,precise,and accessible clinical care in the management of HCC.

关键词： Hepatocellular carcinoma Nanomedicine Ligand-receptor mediated nanotherapy Precision medicine Personalized medicine Targeting

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The association between C-reactive protein to albumin ratio and 6-month neurological outcome in patients with in-hospital cardiac arrest

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World Journal of Emergency Medicine 2024年第3期15卷 223-228页

作者： Ji Ho lee Dong Hun lee Byung Kook lee Seok Jin Ryu Department of Emergency Medicine Chonnam National University HospitalGwangju 61469Republic of Korea Department of Emergency Medicine Chonnam National University Medical SchoolGwangju 61469Republic of Korea

The global incidence rates of in-hospital cardiac arrest(IHCA)range from1.2 to 9.0 per1,000 hospitalized patients,as per the National Cardiac Arrest Database.[1] While IHCAs tend to exhibit superior 30-day survival rates relative to out-of-hospital cardiac arrests (OHCA) due to situational advantages,such as immediate access to medical personnel and treatments.

关键词： patients cardiac IHC

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Phase-driven progress in nanophotonic biosensing

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Light(Science & Applications) 2024年第5期13卷 798-800页

作者： Isabel Barth Hakho lee Center for Systems Biology Massachusetts General HospitalHarvard Medical SchoolBostonMA 02114USA

In the continuous pursuit of enhancing the sensitivity of nanophotonic biosensors by leveraging phase phenomena,a recent development involved the engineering of an atomically thin Ge2Sb2Te5 layer on a silver nanofilm to generate large Goos–Hänchen-shifts associated with phase singularities.The resulting detection limit reached~7×10^(-7)RIU.

关键词： silver Ge2Sb2Te5 pursuit

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Establishment of a chicken intestinal organoid culture system to assess deoxynivalenol‑induced damage of the intestinal barrier function

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Journal of Animal Science and Biotechnology 2024年第3期15卷 1119-1130页

作者： Tae Hong Kang Sang In lee Department of Animal Science and Biotechnology Kyungpook National UniversitySangjuGyeong‑Sangbuk‑Do 37224Republic of Korea Research Institute for Innovative Animal Science Kyungpook National University37224SangjuGyeong‑Sangbuk‑DoRepublic of Korea

Background Deoxynivalenol(DON)is a mycotoxin that has received recognition worldwide because of its ability to cause growth delay,nutrient malabsorption,weight loss,emesis,and a reduction of feed intake in livestock.Since DON-contaminated feedstuff is absorbed in the gastrointestinal tract,we used chicken organoids to assess the DON-induced dysfunction of the small intestine.Results We established a culture system using chicken organoids and characterized the organoids at passages 1 and 10.We confirmed the mRNA expression levels of various cell markers in the organoids,such as KI67,leucine-rich repeat containing G protein-coupled receptor 5(Lgr5),mucin 2(MUC2),chromogranin A(CHGA),cytokeratin 19(CK19),lysozyme(LYZ),and microtubule-associated doublecortin-like kinase 1(DCLK1),and compared the results to those of the small intestine.Our results showed that the organoids displayed functional similarities in permeability compared to the small intestine.DON damaged the tight junctions of the organoids,which resulted in increased permeability.Conclusions Our organoid culture displayed topological,genetic,and functional similarities with the small intes-tine cells.Based on these similarities,we confirmed that DON causes small intestine dysfunction.Chicken organoids offer a practical model for the research of harmful substances.

关键词： Barrier function Deoxynivalenol Organoids

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Enhancing Identity Protection in Metaverse-Based Psychological Counseling System

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Computers, Materials & Continua 2024年第1期78卷 617-632页

作者： Jun lee Hanna lee Seong Chan lee Hyun Kwon Department of Game Software Hoseo UniversityAsan-si31499Korea Yatav Enter Seoul04799Korea Department of Artificial Intelligence and Data Science Korea Military AcademySeoul01805Korea

Non-face-to-face psychological counseling systems rely on network technologies to anonymize information regard-ing client identity.However,these systems often face challenges concerning voice data leaks and the suboptimal communication of the client’s non-verbal expressions,such as facial cues,to the counselor.This study proposes a metaverse-based psychological counseling system designed to enhance client identity protection while ensuring efficient information delivery to counselors during non-face-to-face counseling.The proposed systemincorporates a voicemodulation function that instantlymodifies/masks the client’s voice to safeguard their identity.Additionally,it employs real-time client facial expression recognition using an ensemble of decision trees to mirror the client’s non-verbal expressions through their avatar in the metaverse environment.The system is adaptable for use on personal computers and smartphones,offering users the flexibility to access metaverse-based psychological counseling across diverse environments.The performance evaluation of the proposed system confirmed that the voice modulation and real-time facial expression replication consistently achieve an average speed of 48.32 frames per second or higher,even when tested on the least powerful smartphone configurations.Moreover,a total of 550 actual psychological counseling sessions were conducted,and the average satisfaction rating reached 4.46 on a 5-point scale.This indicates that clients experienced improved identity protection compared to conventional non-face-to-face metaverse counseling approaches.Additionally,the counselor successfully addressed the challenge of conveying non-verbal cues from clients who typically struggled with non-face-to-face psychological counseling.The proposed systemholds significant potential for applications in interactive discussions and educational activities in the metaverse.

关键词： Metaverse counseling system face tracking identity protection

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