检索结果-南通市图书馆

Application of Fuzzy Control to Improve Flow Balance of Multi-Cavity Hot Runner System

在线全文

学校读者我要写书评

暂无评论

Journal of Mechanics Engineering and Automation 2012年第12期2卷 726-741页

作者： Chung-Ching Huang Shin-min Hung Wen-Wang Wu Yi-Jen Yang His-Jung Chang jui-Wen Chang Chih-Husiung Chung Shen-Houng Chen Department of Mold and Die Engineering National Kaohsiung University of Applied Sciences Kaohsiung 807 Taiwan ROC Department of Mechanical Engineering Precision Machinery Research & Development Center Taichung 407 Taiwan ROC

In this study, we propose a new temperature compensation control strategy for a multi-cavity hot runner injection molding system, At first, the melt filling time of each cavity can be measured by installing temperature sensors on the position around end filling area, and filling time difference between the various cavities can be calculated. Then the melt temperature of each hot nozzle can be adjusted automatically by a control strategy established based on the Fuzzy Theory and a program compiled with LABVIEW software. Temperature changes the melt mobility, so the adjustment of temperature can equalize the filling time of the melt in each cavity, which can reduced the mass deviation between each cavity and make product properties of each cavity consistent. The conclusion of the experiment is as follows： For this contact lens box of a four-cavity Hot Runner mold, by applying hot runner temperature compensation control system, time difference can be reduced from 0.05 s to 0.01 s at each cavity, and the mass Standard deviation of the four cavity can be improved from 0.006 to 0.002. The ratio of imbalance can be reduced from 20% to 4%. Hence, the hot runner temperature compensation control system has significant feasibility and high potential in improving melt flow balance of multi-cavity molding application.

关键词： Fuzzy control multi-cavity flow balance hot runner molding technology temperature compensation.

Video-assisted thoracoscopic surgery (VATS) for bilateral primary spontaneous pneumothorax

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第4期9卷 335-340页

作者： Yi-jen CHEN Shi-ping LUH Kun-yen hsu Cheng-ren CHEN Thomas Chang-yao TSAO Jia-yuh CHEN Department of Medicine Chia-Yi Christian Hospital 600 Chia-Yi Taiwan China Department of Thoracic Surgery Chia-Yi Christian Hospital 600 Chia-Yi Taiwan China Department of Medicine Chung-Shan Medical University 402 Taichung Taiwan China Institute of Life Science National Chung-Cheng University 600 Chia-Yi Taiwan China

Objective： To review our experience of the treatment of bilateral primary spontaneous pneumothorax （PSP） by video-assisted thoracoscopic surgery （VATS）. Materials and methods： Retrospective chart review was followed by an on-clinic or telephone interview. Patients were cared for by one thoracic surgeon in four medical centers or community hospitals in Northern and Central Taiwan. Thirteen patients with bilateral PSP underwent bilateral VATS simultaneously or sequentially from July 1994 to December 2005. Results： Twelve males and one female, with age ranging from 15 to 36 years （mean 23.1 years）, were treated with VATS for bilateral PSP, under the indications of bilateral pneumothoracis simultaneously （n=4） or sequentially （n=9）. The interval between the first and second contra-lateral VATS procedure for non-simultaneous PSP patients ranged from 7 d to 6 years. Eleven of 13 patients （84.6%） had prominent pulmonary bullae/blebs, and underwent bullae resection with mechanical or chemical pleurodesis. The mean operative time was （45.6±18.3） min （range 25-96 min） and （120.6±28.7） min （range 84-166 min） respectively for the non-simultaneous （second VATS for the recurrence of contralateral side after first VATS） and simultaneous （bilateral VATS in one operation） procedures. There was no postoperative mortality. However, prolonged air leakage （〉7 d） occurred in one patient （7.7%） who recovered after conservative treatment. The mean duration of chest tube drainage was 3.1 d and the median follow up period was 3.4 years. Conclusions： VATS is a safe and effective procedure in the treatment of bilateral PSP. Bilateral VATS is only recommended for patients with simultaneously bilateral PSP, because the incidence of recurrence, even with visible bullae, was not so high in my group and in some previous literature. Bilateral VATS in a supine position should only be used in selective cases, because of possible pleural adhesion or hidden bullae on the posterior side.

关键词： Video-assisted thoracoscopic surgery (VATS) Spontaneous pneumothorax (SP)

Hepatic arterial infusion chemotherapy for hepatocellular carcinoma with portal vein tumor thrombosis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2003年第12期9卷 2666-2670页

作者： Yung-Chih Lai Cheng-Yen Shih Chin-ming Jeng Sien-Sing Yang jui-Ting Hu Yung-Chuan Sung Han-Ting Liu Shaw-min Hou Chi-Hwa Wu Tzen-Kwan Chen Department of Internal Medicine Cathay General HospitalTaipeiTaiwanChina Department of Radiology Cathay General HospitalTaipeiTaiwanChina Department of Surgery Cathay General HospitalTaipeiTaiwanChina

AIM: Hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) is associated with poor prognosis. The aim of this prospective study was to evaluate the efficacy of hepatic arterial infusion chemotherapy (HAIC) for patients with this ***: Eighteen HCC patients with PVTT were treated with HAIC via a subcutaneously implanted injection port. A course of chemotherapy consisted of daily cisplatin (10 mg for one hour) followed by 5-fiuorouracil (250 mg for five hours) zfor five continuous days within a given week. The patients were scheduled to receive four consecutive courses of *** were defined in whom either a complete or partial response was achieved, while non-responders were defined based on stable or progressive disease status. The prognostic factors associated with survival after treatment were ***: Six patients exhibited partial response to this form of HAIC (response rate = 33 %). The 3, 6, 9, 12 and 18-month cumulative survival rates for the 18 patients were 83 %, 72 %, 50 %, 28 %, and 7 %, respectively. Median survival times for the six responders and 12 non-responders were 15.0 (range, 11-18) and 7.5 (range, 1-13) months,respectively, It was demonstrated by both univariate and multivariate analyses that the therapeutic response and hepatic reserve function were significant prognostic ***: HAIC using low-dose cisplatin and 5-fluorouracil may be a useful alternative for the treatment of patients with advanced HCC complicated with PVTT. There may also be survival-related benefits associated with HAIC.

关键词：肝动脉灌注化疗门静脉肿瘤栓塞肝细胞癌影像学检查临床研究

Low Input and High Output Impedances Current-Mode First-Order Allpass Filter Employing Grounded Passive Components

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Circuits and Systems 2012年第2期3卷 176-179页

作者： Jiun-Wei Horng Chun-Li Hou Yi-Sing Guo Chih-Hou hsu Dun-Yih Yang min-Jie Ho Department of Electronic Engineering Chung Yuan Christian University Chung-Li Chinese Taipei

A current-mode low input and high output impedances first-order allpass filter using two multiple output second-generation current conveyors (MOCCIIs), one grounded capacitor and one grounded resistor is presented. The suggested filter uses a canonical number of passive components without requiring any component matching condition. The frequency responses simulation results of the proposed filter confirm the theoretical analysis.

关键词： Second-Generation Current Conveyor First-Order Filter Allpass Current-Mode

利用重力卫星GRACE监测亚马逊流域2002-2010年的陆地水变化

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

地球物理学报 2012年第3期55卷 814-821页

作者：冯伟 Jean-Michel LEMOINE 钟敏许厚泽中国科学院测量与地球物理研究所大地测量与地球动力学国家重点实验室武汉430077 中国科学院研究生院北京100049 CNES/GRGS ToulouseFrance 31401 华中科技大学地球物理研究所武汉430074

本文利用GRACE(Gravity Recovery and Climate Experiment)卫星重力资料研究了亚马逊流域2002—2010年的陆地水变化,并与水文模式和降雨资料进行了比较分析.在年际尺度上,GRACE结果表明:2002—2003年和2005年,亚马逊流域发生明显的干旱... 详细信息

本文利用GRACE(Gravity Recovery and Climate Experiment)卫星重力资料研究了亚马逊流域2002—2010年的陆地水变化,并与水文模式和降雨资料进行了比较分析.在年际尺度上,GRACE结果表明:2002—2003年和2005年,亚马逊流域发生明显的干旱现象;2007年至2009年,陆地水呈逐年增加的趋势,并在2009年6月变化值达到最大,为772±181km3;自2009年6月至2010年12月,陆地水总量又急剧减少了1139±262km3,这相当于全球海平面上升3.2±0.7mm所需的水量.水文模式得到的亚马逊流域陆地水在2010年也表现出明显的减少.降雨资料与GRACE观测资料有很好的一致性.在2005年和2010年的干旱期,亚马逊流域的降雨显著减少,说明降雨是亚马逊流域陆地水变化的重要因素.此外,本文采用的尺度因子的方法有效地降低了GRACE后处理误差的影响.

关键词： GRACE 亚马逊流域陆地水

minimally Invasive Open Reduction and Internal Fixation for Osteoporotic Vertebral Compression Fractures: Technical Report and Mid-Term Outcomes

在线全文

学校读者我要写书评

暂无评论

Open Journal of Orthopedics 2018年第9期8卷 337-350页

作者： jui-Yang Hsieh Po-Quang Chen Jyh-Horng Wang Department of Orthopedics National Taiwan University Hospital and Jinshan Branch Taiwan Department of Orthopedics National Taiwan University Hospital Taiwan Department of Orthopedics Min-Sheng General Hospital Taiwan

Background: Traditional open instrumentation may cause surgical complications due to fragile bones and induce medical comorbidities in senile patients. Vertebroplasty and kyphoplasty are palliative augmentation procedures that have been associated with increased risks of cement leakage, adjacent fractures and non-union. Objective: The aim of this study was to describe a novel approach for the union of osteoporotic vertebral compression fractures with minimally invasive open reduction and internal fixation. Patients and Methods: Seven consecutive patients with intractable back pain without neurological deficits due to osteoporotic vertebral compression fractures were treated using minimally invasive fixation with intra-vertebral expandable pillars and artificial bone substitute. The clinical symptoms and image findings were recorded. Results: All of the patients reported relief of back pain, and the height of the vertebral bodies was well restored. X-ray findings obtained 2 to 4 years after the procedures showed fracture healing and favorable formation of the callus confirmed in the anterior longitudinal ligament. Conclusion: This mini-open procedure with intravertebral devices is an effective and reliable technique for osteoporotic vertebral compression fractures and may avoid complications related to traditional open spinal instrumentation procedures and augmentation with bone cement.

关键词： Osteoporotic Vertebral Compression Fracture minimally Invasive Spine Surgery Intra-Vertebral Expandable Pillar Fracture Union Bone Cement

Lamivudine does not increase the efficacy of interferon in the treatment of mutant type chronic viral heaptitis B

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2002年第5期8卷 868-871页

作者： Sien-Sing Yang jui-Ting Hu Yung-Chih Lai Chi-Hwa Wu Liver Unit,Cathay General Hospital,Taipei,Taiwan,China Sien-Sing Yang Chao-Tien hsu Medical Faculty,China Medical College and Hospital,Taichung,Taiwan,China Sien-Sing Yang Jui-Ting Hu Yung-Chih Lai Chi-Hwa Wu Liver Unit Cathay General Hospital Taipei Taiwan China Sien-Sing Yang Chao-Tien Hsu Medical Faculty China Medical College and Hospital Taichung Taiwan China

AIM：To study the role of lamivudine in improving the efficiency of interferon for the treatment of mutant type chronic hepatits ***:Fifteen patients with mutant type chronic hepatitis Bwere prospectively *** patients had liver histology and serology to prove the diagnosis of chronic hepatitis *** patient received4.5millionunits of interferon alpha-2a thrice weekly and 100mg of oral lamivudine daily for *** were observed and tested for blood chemistry every week for the initial 4weeks and every 2weeks thereafter during the treatment until *** the end of treatment,patients were followed up at4-week intervals for an additional6months,SerumHBVDNAlevels were tested using the liquid phase molecular hybridization *** with non-detectable HBVDNA were also tested using the real-time polymerase chain *** patient,who did not finish treatment due to *** ***:At the end of treatment.7(50%)patients had serum ALTlevels within normal limits:12(86%)patients had serumHBVDNAlevels<5pg/mLusing the liquid phase molecular hybridization assay,but only8(67%)were<20copies/dL using the real-time polymerase chain reaction Six months after treatment only two(14%)patents had a susained complete response to the combination therapy with serum ALTlevel<35iu/Land undetectable serum HBVDNA ***:These pilot data showed that lamivudine did not increase the efficacy of interferon in the treatment of mutant type chronic *** liquid phase molecular hbridization assay was not sensitive enough to detect the lov HBVDNAlevels during combined interferon and lamivudine therapy.

关键词：拉米夫定突变性慢性乙型肝炎干扰素治疗

YTHDF2-mediated regulations bifurcate BHPF-induced programmed cell deaths

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

National Science Review 2023年第12期10卷 83-97页

作者： Jiebo Lin Guankai Zhan Jinfeng Liu Yasen Maimaitiyiming Zhiping Deng Baohua Li Kunhui Su Jiafeng Chen Siqi Sun Wanlin Zheng Xianghui Yu Feng He Xiaodong Cheng Lingfang Wang Bin Shen Ziqin Yao Xinquan Yang Jian Zhang Wentao He Hengyu Wu Hua Naranmandura Kao-Jung Chang Junxia min Jun Ma Mikael Bj?rklund Peng-Fei Xu Fudi Wang Chih-Hung hsu Women's Hospital The Fourth Affiliated Hospitaland Department of Environmental MedicineZhejiang University School of Medicine Institute of Genetics International School of MedicineZhejiang University The Second Affiliated Hospital School of Public Health State Key Laboratory of Experimental Hematology Zhejiang University School of Medicine Department of Hematology of First Affiliated Hospital and Department of Public Health Zhejiang University School of Medicine State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products Institute of Virology and Biotechnology Zhejiang Academy of Agricultural Sciences Department of Obstetrics Women's Hospital School of Medicine Zhejiang University Women's Hospital and Institute of Genetics Zhejiang University School of Medicine Zhejiang Provincial Key Lab of Genetic and Developmental Disorders Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine State Key Laboratory of Reproductive Medicine Center for Global HealthGusu School Women's Hospital of Nanjing Medical University Nanjing Maternity and Child Health Care Hospital Nanjing Medical University The First Affiliated Hospital Basic Medical SciencesSchool of Public HealthSchool of Pharmaceutical Science Hengyang Medical School University of South China Department of Medical Research Taipei Veterans General Hospital The First Affiliated Hospital Institute of Translational MedicineCancer Center Zhejiang University School of Medicine Zhejiang University-University of Edinburgh (ZJU-UoE) Institute University of Edinburgh Medical School Biomedical SciencesCollege of Medicine & Veterinary MedicineUniversity of Edinburgh

N6-methyladenosine(m6A) is a critical regulator in the fate of RNA, but whether and how m6A executes its functions in different tissues remains largely obscure. Here we report downregulation of a crucial m6A reader, YTHDF2, leading to tissue-specific programmed cell deaths(PCDs) upon fluorene-9-bisphenol(BHPF) exposure. Currently, Bisphenol A(BPA) substitutes are widely used in plastic *** eight common BPA substitutes, we detected BHPF in 14% serum samples of pregnant participants. In a zebrafish model, BHPF caused tissue-specific PCDs triggering cardiac and vascular ***, BHPF-mediated downregulation of YTHDF2 reduced YTHDF2-facilitated translation of m6A-gch1 for cardiomyocyte ferroptosis, and decreased YTHDF2-mediated m6A-sting1 decay for caudal vein plexus(CVP) apoptosis. The two distinct YTHDF2-mediated m6A regulations and context-dependent co-expression patterns of gch1/ythdf2 and tnfrsf1a/ythdf2 contributed to YTHDF2-mediated tissue-specific PCDs, uncovering a new layer of PCD regulation. Since BHPF/YTHDF2-medaited PCD defects were also observed in mammals, BHPF exposure represents a potential health threat.

关键词： RNA m6A modification programmed cell deaths bifurcation role of YTHDF2 environmental stress and m6A regulation fluorene-9-bisphenol (BHPF)

基于时空域混合法利用Kaula正则化精确和快速解算GOCE地球重力场

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

地球物理学报 2011年第1期54卷 14-21页

作者：郑伟许厚泽钟敏员美娟周旭华中国科学院测量与地球物理研究所动力大地测量学重点实验室武汉430077 日本京都大学防灾研究所武汉科技大学应用物理系武汉430081 中国科学院上海天文台上海200030

为了研究卫星重力梯度技术对中高频地球重力场反演精度的影响,本文基于时空域混合法,利用Kaula正则化反演了250阶GOCE地球重力场.模拟结果表明:第一,时空域混合法是精确和快速求解高阶地球重力场的有效方法;第二,Kaula正则化是降低正规... 详细信息

为了研究卫星重力梯度技术对中高频地球重力场反演精度的影响,本文基于时空域混合法,利用Kaula正则化反演了250阶GOCE地球重力场.模拟结果表明:第一,时空域混合法是精确和快速求解高阶地球重力场的有效方法;第二,Kaula正则化是降低正规阵病态性的重要方法;第三,基于改进的预处理共轭梯度迭代法可快速求解大型线性方程组,计算速度较直接最小二乘法至少提高1000倍;第四,基于卫星轨道误差1 cm和卫星重力梯度误差3×10^(-12)/s^2,在250阶处反演累计大地水准面和重力异常的精度分别为9.295 cm和0.204 mGal.第五,论证了基于国际GRACE和GOCE卫星计划反演高精度和高空间分辨率地球重力场的互补性.

关键词： GOCE 时空域混合法 Kaula正则化卫星重力梯度地球重力场