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同期三尖瓣成形与单纯封堵治疗房间隔缺损合并继发性中重度三尖瓣关闭不全的倾向性评分匹配研究

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中国胸心血管外科临床杂志 2024年第4期31卷 519-524页

作者：陈天钰刘晓冰余觉愍任秋实邱海龙温树生庄建广东省人民医院广东省医学科学院、广东省心血管病研究所心外科广州510080

目的比较外科同期三尖瓣成形与单纯介入封堵治疗房间隔缺损(atrial septal defect,ASD)合并中重度三尖瓣关闭不全的效果。方法回顾性分析2009年1月—2020年6月广东省人民医院ASD合并继发性中重度三尖瓣关闭不全患者的临床资料。根据是... 详细信息

目的比较外科同期三尖瓣成形与单纯介入封堵治疗房间隔缺损(atrial septal defect,ASD)合并中重度三尖瓣关闭不全的效果。方法回顾性分析2009年1月—2020年6月广东省人民医院ASD合并继发性中重度三尖瓣关闭不全患者的临床资料。根据是否同期行三尖瓣成形术将患者分为成形组和非成形组。对两组患者基线资料进行1∶1倾向性评分匹配。结果257例患者中共32对成功匹配。成形组女24例、男8例,平均年龄(44.0±13.1)岁;非成形组女28例、男4例,平均年龄(44.5±11.6)岁。随访时两组患者的三尖瓣反流面积均较术前显著减少(P均<0.001),估测肺动脉压显著降低(P均<0.001)。与非成形组相比,成形组的三尖瓣反流面积减少更多(P=0.001)、估测肺动脉压降低更明显(P=0.002)。线性回归分析显示,年龄、术前三尖瓣反流面积与随访时三尖瓣反流面积呈正相关(β=0.045、0.259,P均<0.05),而同期三尖瓣成形与随访时三尖瓣反流面积呈负相关(β=–1.542,P=0.001)。结论同期三尖瓣成形可显著减少三尖瓣反流面积及降低肺动脉压,年龄大、术前严重三尖瓣关闭不全的患者应积极行三尖瓣成形。

关键词：房间隔缺损三尖瓣关闭不全三尖瓣成形介入封堵倾向性评分匹配

基于AHP-DS异质数据融合的建筑空间占用感知算法

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软件 2024年第3期45卷 42-47页

作者：杨镇宇吴晓菲魏昕顾小军唐觉民南京邮电大学通信与信息工程学院江苏南京210003 安徽建筑大学智能建筑与建筑节能安徽省重点实验室安徽合肥230022 南京长江都市建筑设计股份有限公司江苏南京210002

智慧建筑智能控制系统旨在优化建筑物的建筑空间舒适度及能源分配,近年来受到了广泛关注,而建筑空间占用信息对智慧建筑管理系统的决策具有重要作用。现有建筑空间占用感知方法尚未针对如何融合具有不确定性、冲突性的多源数据问题提出... 详细信息

智慧建筑智能控制系统旨在优化建筑物的建筑空间舒适度及能源分配,近年来受到了广泛关注,而建筑空间占用信息对智慧建筑管理系统的决策具有重要作用。现有建筑空间占用感知方法尚未针对如何融合具有不确定性、冲突性的多源数据问题提出有效解决方案,基于此,本文将D-S证据理论引入建筑空间占用预测中,并构建了基于建筑空间占用检测的mass函数确保D-S证据理论在该应用中的性能。另外,本文引入层次分析法(Analytic Hierarchy Process,AHP)解决多源异构数据源间的冲突所导致的建筑空间占用误测的问题,以提升感知精准度和系统性能。

关键词：智慧建筑建筑空间占用检测 D-S证据理论多源异构数据融合

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智慧建筑研究现状与发展展望

绿色建造与智能建筑 2024年第1期 83-87页

作者：郭振伟王新雨唐觉民赵蕊王有为中国城市科学研究会北京100080 南京长江都市建筑设计研究院有限公司南京210002

智慧建筑采用物联网、传感器、多媒体融合、定位与导航、建筑信息模型、大数据分析、人工智能等众多新兴前沿技术,是集现代科学技术于一体的产物,是多行业交叉融合的综合成果。在全球工业4.0和我国数字化转型的推动下,作为智慧城市和智... 详细信息

智慧建筑采用物联网、传感器、多媒体融合、定位与导航、建筑信息模型、大数据分析、人工智能等众多新兴前沿技术,是集现代科学技术于一体的产物,是多行业交叉融合的综合成果。在全球工业4.0和我国数字化转型的推动下,作为智慧城市和智慧中国的重要元素,智慧建筑将成为我国建筑、信息通信和互联网等领域的未来发展趋势及研究热点之一。本文首先梳理总结了国内外智慧建筑的发展历程,其次重点介绍了我国智慧建筑的研究进展,对最新政策制度、科学研究、评价标准和工程实践等进行了回顾,再次从智慧建筑评价项目出发,对技术措施和得分情况进行了讨论,最后结合我国国情及建筑行业现状,对智慧建筑发展进行了展望,提出了未来应用方向,可为我国智慧建筑发展提供参考。

关键词：智慧建筑发展历程评价标准技术应用

Splicing factor SF3B3,a NS5-binding protein,restricts ZIKV infection by targeting GCH1

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Virologica Sinica 2023年第2期38卷 222-232页

作者： Tanxiu Chen Hao Yang Penghui Liu Moliduer Hamiti Xintian Zhang Yi Xu Wenqi Quan Yong Zhang Wenhai Yu Li Jiao Tingfu Du juemin Xi Bin Yin Wei Zhou Shuaiyao Lu Xiaozhong Peng Institute of Medical Biology Chinese Academy of Medical Sciences and Peking Union Medical CollegeKunming650031China Department of Science and Education Jiangxi Key Laboratory of Translational Cancer ResearchJiangxi Cancer HospitalNanchang330029China The State Key Laboratory of Medical Molecular Biology Department of Molecular Biology and BiochemistryInstitute of Basic Medical SciencesMedical Primate Research CenterNeuroscience CenterChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing100730China

Zika virus(ZIKV),a positive-sense single-stranded RNA virus,causes congenital ZIKV syndrome in children and Guillain-Barre Syndrome(GBS)in *** expresses nonstructural protein 5(NS5),a large protein that is essential for viral *** NS5 confers the ability to evade interferon(IFN)signalling;however,the exact mechanism remains *** this study,we employed affinity pull-down and liquid chromatography-tandem mass spectrometry(LC-MS/MS)analyses and found that splicing factor 3b subunit 3(SF3B3)is associated with the NS5-Flag pull-down complex through interaction with *** assays showed that SF3B3 overexpression inhibited ZIKV replication by promoting IFN-stimulated gene(ISG)expression whereas silencing of SF3B3 inhibited expression of ISGs to promote ZIKV *** cyclohydrolase I(GCH1)is the first and ratelimiting enzyme in tetrahydrobiopterin(BH4)***5 upregulates the expression of GCH1 during ZIKV *** GCH1 marginally promoted ZIKV replication via the IFN ***,GCH1 expression is related to the regulation of *** of the SF3B3 protein effectively reduced GCH1 protein levels,whereas SF3B3 knockdown increased its *** findings indicated that ZIKV NS5 binding protein SF3B3 contributed to the host immune response against ZIKV replication by modulating the expression of GCH1.

关键词： Nonstructural protein 5(NS5) Splicing factor 3b subunit 3(SF3B3) GTP cyclohydrolase I(GCH1) IFN-stimulated gene(ISGs) IFN signalling Pathway

Field-level characterization of strong coupling between excitons and surface plasmon polaritons in J-aggregate/metal hybrid nanostructures

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光电工程 2017年第2期44卷 202-208+242页

作者： Wei Wang Ephraim Sommer Antonietta De Sio Parinda Vasa juemin Yi Hong Zhang College of Physical Science and Technology Sichuan University Institut für Physik Carl von Ossietzky Universit?t Key Laboratory of High Energy Density Physics and Technology of Ministry of Education Sichuan University Department of Physics Indian Institute of Technology

White-light broadband chirp-compensated spectral interferometry is applied to fully probe the optical response of strongly coupled excitons(Xs)and surface plasmon polaritons(SPPs)in J-aggregate/metal hybrid nanostructures at field *** impulsive excitation,amplitude and spectral phase of the sample reflectivity are measured with high precision and the time structure of the electric field emitted by the hybrid modes of the nanostructures is accurately *** description of strong X-SPP coupling is precisely obtained by fitting both measured spectra and phases simultaneously to a Fano lineshape model.

关键词： surface plasmon polaritons spectral interferometry subwavelength nanostructures strong coupling

Defect evolution in GaN thin film heterogeneously integrated with CMOS-compatible Si(100) substrate by ion-cutting technology

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Science China(Information Sciences) 2023年第11期66卷 313-314页

作者： Hangning SHI Ailun YI Jiaxin DING Xudong LIU Qingcheng QIN juemin YI Junjie HU Miao WANG Demin CAI Jianfeng WANG Ke XU Fengwen MU Tadatomo SUGA René HELLER Mao WANG Shengqiang ZHOU Wenhui XU Kai HUANG Tiangui YOU Xin OU State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences University of Chinese Academy of Sciences School of Materials and Chemistry University of Shanghai for Science and Technology Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou Nanowin Science and Technology Co. Ltd. SABers Co. Ltd. Collaborative Research Center Meisei University Helmholtz-Zentrum Dresden-Rossendorf Institute of Ion Beam Physics and Materials Research College of Physics and Electronic Engineering Sichuan Normal University

Ion-cutting technology is an ingenious solution to the highquality heterogeneous integration of Ga N thin films with CMOS-compatible Si(100) substrate, which provides a platform to combine Ga N-based optoelectronics, high-frequency and high-power electronics with digital signal processing,logic computation, and control of Si(100) CMOS [1].

关键词： Gallium nitride

Polypyrimidine Tract-Binding Protein Regulates Enterovirus 71 Translation Through Interaction with the Internal Ribosomal Entry Site

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Virologica Sinica 2019年第1期34卷 66-77页

作者： juemin Xi Fei Ye Guanzhou Wang Wei Han Zhizhong Wei Bin Yin Jiangang Yuan Boqin Qiang Xiaozhong Peng Institute of Medical Biology Chinese Academy of Medical Sciencesand Peking Union Medical College The State Key Laboratory of Medical Molecular Biology Department of Molecular Biology and BiochemistryInstitute of Basic Medical SciencesChinese Academy of Medical Sciences and Peking Union Medical College

Enterovirus 71(EV71), a major causative agent of hand, foot, and mouth disease, has caused periodic infection outbreaks in children in the Asia–Pacific region. In order to describe the largely unknown life cycle of EV71, the molecular basis of its virus-host interactions must first be determined. The 50 untranslated region of EV71 contains a cloverleaf-like structure and internal ribosomal entry site(IRES), which play an important role in transcription and translation of viral protein. We found that polypyrimidine tract-binding protein 1(PTB) bound to the IRES of EV71. RNA recognition motifs 1 and 2 of PTB were responsible for its binding to the EV71 IRES. Moreover, PTB protein was shuttled from nucleus to cytoplasm after EV71 infection. Additionally, IRES activity and viral protein production were inhibited by PTB knockdown. These results suggest that PTB interacts with the EV71 IRES, and positively regulates viral protein translation.

关键词： EV71 IRES PTB Translation

KITCHEN RANGE PAINTING OF JIAXING

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China & The World Cultural Exchange 2008年第2期74卷 44-46页

作者： Zhang juemin

Every household in Jiaxing’s villages has a two-stove-opening or three-stove opening kitchen range. Dazzling arrays of patterns and designs with text captions are painted on the surface of kitchen ranges,which are ca... 详细信息

关键词：嘉兴厨房绘画艺术民间艺术

Reminiscences of Kochen Chu, My Teacher

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文化交流 1997年第1期 18-19页

作者： Xie juemin Guo Chengang

Two accomplished educators stood out inthe history of China during 20th *** *** Yuanpei and the other is *** *** World War Two,Zhejiang Universitymoved four times due to the attack ofJapanese *** by Chu,president ofZh... 详细信息

关键词： My Teacher Reminiscences of Kochen Chu