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英国医学杂志中文版 2016年第12期19卷 677-677页

作者： Jessica Preisler Julia Kopeika Laure Ismail Veluppillai Vathanan Jessiea Fatten Yazan Abdallah Parijat Battacharjee Caroline VanHolsbeke Cecilia Bottomley Deborah Gould SusanneJohnson Catriona Stalder Ben Van Calster judith hamilton Dirk Timmerman Tom Bourne 杨慧丽杨孜不详北京大学第三医院妇产科

目的验证最新指南中已确定的胚胎顶臀径和妊娠囊平均直径分界值的变更对诊断流产有较高的可信度。其次是检测妊娠囊平均直径和顶臀径的大小与胎龄之间的相关性，确定初次超声检查与再次复查超声确诊妊娠失败之间的最佳间隔时间。

关键词：流产诊断标准胚胎顶臀径妊娠囊平均直径分界值

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Nociceptive and Neuropathic Pain Qualities in Men and Women with Acute Coronary Syndromes: A Complex Pain Presentation

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Open Journal of Nursing 2017年第3期7卷 331-344页

作者： Sheila O’Keefe-McCarthy Michael McGillion Charles J. Victor Sheila Rizza judith McFetridge-Durdle Brock University St. Catharines Ontario Canada Heart and Stroke Foundation/Michael G. De Groote Endowed Chair in Cardiovascular Nursing Research School of Nursing Faculty of Health Sciences Hamilton Ontario Canada University of Toronto Toronto Ontario Canada Nurse Practitioner Heart Failure Clinic Trillium Health Partners-Credit Valley Site Mississauga Ontario Canada Florida State University College of Nursing Tallahassee Florida US

Background: Cardiac pain arising from acute coronary syndrome (ACS) is a multi-factorial phenomenon. Historically, episodes of cardiac pain have been captured using a one-dimensional numeric pain rating scale. Lacking in clinical practice are acute pain assessments that employ a comprehensive evaluation of an emergent ACS episode. Aim: To examine the sensory-discriminative, motivational-affective and cognitive-evaluative dimensions of ACS-related pain. Methods: A descriptive-correlational, repeated-measure design was used to collect data on 121 ACS patients of their cardiac pain intensity. The (numeric rating scale-NRS 0-10 scale) measured chest pain “Now” and “Worst pain in the previous 2 hours over 8 hours” and the McGill Pain Questionnaire Short-Form (MPQ-SF) measured pain at 4 hours. Results: Mean age was 67.6 ± 13, 50% were male, 60% had unstable angina and 40% had Non-ST-elevation myocardial infarction. Cardiac pain intensity scores remained in the mild range from 1.1 ± 2.2 to 2.4 ± 2.7. MPQ-SF: 66% described pain as distressing and 26% reported pain was horrible or excruciating. Participants described ACS pain quality as acute injury (nociceptive pain: heavy, cramping, stabbing), as nerve damage (neuropathic: gnawing, hot-burning, shooting) and as a mixture of acute and chronic pain qualities (aching, tender and throbbing). Conclusions: Patients reported both nociceptive and neuropathic cardiac pain. It is unclear if pain perceptions are due to: i) pathophysiology of clot formation, ii) occurrence of a first or repeated ACS episode, or iii) complex co-morbidities. Pain arising from ACS requires an understanding of the interplay of ischemic, metabolic and neuropathophysiological mechanisms that contribute to complex cardiac pain experiences.

关键词： Acute Coronary Syndromes Nociceptive Pain Neuropathic Pain Pain Descriptors Emergency Department

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Viral Hepatitis B and C Detection among Ebola Survivors and Health Care Workers in Makeni, Sierra Leone

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Journal of Biosciences and Medicines 2020年第10期8卷 18-32页

作者： Nadege Goumkwa Mafopa Marta Giovanetti Raoul Emeric Guetiya Wadoum Antonella Minutolo Claude Kwe Yinda Gianluca Russo Béatrice Dambaya Georges Teto Georgia Ambada Patrick Turay judith Torimiro Alexis Ndjolo Vittorio Colizzi Carla Montesano Chantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management Yaoundé Cameroon University of Roma “Tor Vergata” Rome Italy National Institute of Health-ISS Rome Italy University of Makeni Sierra Leone National Institute of Health (NIH) Intramural Research Program (IRP) Hamilton Montana USA University di Roma “Sapienza” Rome Italy Chantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management University of Yaoundé I Yaoundé Cameroon Holy Spirit Hospital Makeni Sierra Leone Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon

Viral hepatitis B and C infections are among the leading cause of death in Sub-Saharan Africa. Lack of knowledge and awareness in the general population as in health care settings may enhance the propagation of these diseases. We aimed at determining the prevalence of HBV and HCV in Ebola survivors and health care workers (HCWs) of the Makeni town in Sierra Leone. We conducted a cross-sectional study during the last 2013-2016 Ebola outbreak in Makeni among Ebola survivors (N = 68) and 81 Health care workers from Holy Spirit hospital and Loreto clinic, two health care facilities in Makeni district. Serological markers of HBV (HBs Ag, anti-HBs Ab and anti-HBc Ab) and anti-HCV antibodies detection were done using ELISA techniques. The positive detection rates for HBs Ag, anti-HBs Ab and anti-HBc antibodies in Ebola survivors were 23.53% (16/68), 32.35% (22/68) and 88.89% (16/18) respectively. Survivors with a current HBV infection had a positive rate of 38.89% (7/18) and 16.66% (3/18) of them were considered immune due to past HBV infection. HCV prevalence was 26.47% (18/68) and about 10.29% (7/68) were HBV/HCV co-infected. The positive detection rates of HBsAg, anti-HBs Ab and anti-HBc Ab were 37.07% (30/81), 33.33% (27/81) and 30.86% (25/81) respectively in health care workers. We observed that 4.94% (4/81) of the HCWs were currently infected with HBV. Participants considered as immune due to past infection represented 23.47% (19/81) and those immune due to vaccination represented 2.47% (2/81). The prevalence of HCV infection among health staff was 2.47% (2/81) with 1.23% (1/81) being HBV/HCV co-infection. Our findings showed that viral hepatitis infection is a burden for Sierra Leone government. There is an urgent need to develop and implement strategies that could improve population immunization against HBV and vulgarization of HCV treatment programs.

关键词： Viral Hepatitis B and C Ebola Survivors Health Care Workers

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