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Rituximab as a treatment for human immunodeficiency virusassociated nemaline myopathy:What does the literature have to tell us?

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World journal of Clinical Cases 2022年第4期10卷 1454-1456页

作者： jucier gonçalves júnior Samuel Katsuyuki Shinjo Division of Rheumatology São Paulo UniversitySão Paulo 01246-903Brazil

We presented a letter about a case of a 37-year-old Black female with a history of human immunodeficiency virus and an undetectable viral *** was evaluated with weakness in the scapular(grade III)and pelvic girdles(grade II),elevation of creatine phosphokinase levels and muscle biopsy compatible with nemaline *** was treated with rituximab showing improvement of the condition.

关键词： Case report Human immunodeficiency virus Nemaline myopathy Rituximab Rheumatology Therapy

Reflections on the prevalence of human leukocyte antigen-B27 and human leukocyte antigen-B51 co-occurrence in patients with spondylarthritis

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World journal of Clinical Cases 2022年第23期10卷 8422-8424页

作者： jucier gonçalves júnior Percival Degrava Sampaio-Barros Samuel Katsuyuki Shinjo Division of Rheumatology São Paulo UniversitySão Paulo 01246-903São PauloBrazil

We performed a literature mini-review of the clinical profile of patients with spondylarthritis who are also human leukocyte antigen(HLA)-*** seems to us that patients with HLA-B27 and HLA-B51 are more common in men,Asians and between the third and ninth decades of *** are more likely to develop peripheral joint conditions,with cutaneous manifestations(e.g.,oral ulcers)and ***,more robust epidemiological studies with more accurate methodology and multicenter locations are needed to better map the role of the interaction between HLA-B51 in patients with spondylarthritis.

关键词： HLA-B27 HLA-B51 Ankylosing spondylitis Spondylarthritis Human leukocyte antigen

COVID-19,mental health and Indigenous populations in Brazil:The epidemic beyond the pandemic

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World journal of Psychiatry 2022年第5期12卷 766-769页

作者： jucier gonçalves júnior jucycler Ferreira Freitas Estelita Lima Cândido Internal Medicine-Division of Rheumatology São Paulo UniversitySão Paulo 01246-903Brazil Post Graduate Program in Sustainable Regional Development Federal University of CaririJuazeiro do Norte 63048-080CearaBrazil

The aim of this paper was to report on factors contributing to the deterioration of the mental health of Indigenous populations(IP)in *** factors seem to have a direct impact on the mental health of IP in Brazil:(1)The absence of public policies;(2)Intellectual production;(3)Psychiatric medical care for remote areas(e.g.,telemedicine)aimed at promoting the mental health of Brazil’s IP,which causes a huge gap in the process of assistance and social,psychological,economic and cultural valorization of native peoples;(4)The dissemination of fake news,which exposed,above all,older IP to risk behaviors in the pandemic,such as refusal of vaccination;and(5)The violence carried out on IP lands due to economic interests with mining/agribusiness.

关键词： Brazil COVID-19 Indigenous population Mental health Public health

Impacts of COVID-19 on children and adolescents:A systematic review analyzing its psychiatric effects

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World journal of Psychiatry 2022年第11期12卷 1313-1322页

作者： Italo Wanderson de Moura Gabriel Danielly gonçalves Sombra Lima jeully Pereira Pires Nélio Barreto Vieira Aloisio Antonio Gomes de Matos Brasil Yara Talita Gomes Pereira Erika Galvao de Oliveira HildsonLeandro de Menezes Nadia Nara Rolim Lima Alberto Olavo Advíncula Reis Ruan Neto Pereira alves Uanderson Pereira da Silva jucier gonçalves junior Modesto Leite Rolim-Neto School of Medicine Faculty of Medicine of Juazeiro do Norte-FMJ/IDOMEDJuazeiro do Norte 63040-360CearaBrazil School of Medicine Federal University of CaririBarbalha 63048-080CearaBrazil Mais Médicos Program Federal Government of Brazil-Ministry of HealthIguatu 63048-080CearaBrazil julio alves de Lira Hospital and Maternity Hospital HALHMBelo Jardim 55157-290PernambucoBrazil Nursing Department Doctor Leão Sampaio University Center-UNILEAOJuazeiro do Norte 63.041-140CearaBrazil julio alves de Lira Hospital and Maternity Hospital JALHMBelo Jardim 55157-290PernambucoBrazil Graduate Program(Post-Doctoral)in Neuro-Psychiatry UFPERecife 50670-901PernambucoBrazil Postgraduate Program(Master’s and Doctorate)in Public Health University of São Paulo-USPSão Paulo 01246-904São PauloBrazil School of Education USPSão Paulo 05508-040São PauloBrazil Internal Medicine-Division of Rheumathology at Hospital das Clínicas São Paulo UniversitySão Paulo 01246-903São PauloBrazil

OBjECTIVE To summarize the most relevant data from a systematic review on the impact of COVID-19 on children and adolescents,particularly analyzing its psychiatric *** This review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses(PRISMA)guidelines and included experimental studies(randomized-individually or pooled-and non-randomized controlled trials),observational studies with a group for internal comparison(cohort studies-prospective and retrospective-and case-control)and qualitative studies in the period from 2021 to *** The search identified 325 articles;we removed 125 *** selected 200 manuscripts,chosen by title and selected *** excluded 50 records after screening titles and abstracts,as they did not meet the inclusion *** retrieved 150 records selected for a full *** excluded 90 text articles and we selected 25 records for the(n)***:Due to the short period of data collection,from 2021 to 2022,there is a possibility of lack of relevant studies related to the mental health care of children and *** addition,there is the possibility of publication bias,such as only significant findings being *** The impact of COVID-19 on the mental health of children and adolescents is of great concern to child and youth *** such as fear,anxiety,panic,depression,sleep and appetite disorders,as well as impairment in social interactions caused by psychic stress,are punctual markers of pain and psychic suffering,which have increasing impacts on the mental health panorama of children and adolescents globally,particularly in vulnerable and socially at-risk populations.

关键词： Child psychiatry Adolescent psychiatry Mental health COVID-19 Kids Teens

Suicide among Physicians and Methodological Similarities of MEDLINE/PubMED and BVS/BIREME Open Access Bibliographic Databases: A Systematic Review with Metanalysis

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Health 2017年第2期9卷 352-375页

作者： Ké cia Silva Damasceno élcio de Sousa Barbosa joã o Vitor Candido Pimentel Antonio Gilvan Teixeira jú nior Airton Cé sar Pinheiro de Meneses jucier gonç alves jú nior Danilo Ferreira de Sousa Paulo Sé rgio da Costa Lima Iara Bezerra Sales Antonio Souto Gouveia Elisabethe Peres Biruel Modesto Leite Rolim Neto Vania Barbosa do Nascimento Health Sciences Posgraduation Program Faculdade de Medicina do ABC-FMABC Santo Andr&eacute SP Brazil Medicine Course School of Medicine Universidade Federal do Cariri-UFCA Barbalha CE Brazil Library Science Degree Course Universidade Federal do Cariri-UFCA Juazeiro do Norte CE Brazil Nursing Course Faculdade de Juazeiro do Norte-FJN Juazeiro do Norte CE Brazil Information Systems Course Faculdade de Juazeiro do Norte-FJN Juazeiro do Norte CE Brazil Latin American and Caribbean Center on Health Sciences Information-BIREME S&atilde o Paulo SP Brazil

Background: Suicide among physicians is a serious public health issue, with an extremely complex and multifactorial behavior. Aim: The aim of this study was to use the theme “Suicide among Physicians” to exemplify the analysis of methodological similarities between the scientific content available at MEDLINE and BVS databases, as scientific research tools. Methods: This is a systematic review with metanalysis. The following combinations of keywords were used for data search in the referred databases: “suicide” AND “physicians” AND “public heath”. Results: Three hundred and thirteen publications were identified, but only 16 studies were chosen. Great association was found between MEDLINE and BVS databases and the Odds Ratio regarding the theme: “Suicide among physicians”. Conclusions: Considering the similarities found in the utilization of the two analyzed databases, it was possible to identify that suicide among physicians is associated with the exercise of an important professional role in the society and in the workplace. With regard to scientific information, the p-value-obtained value (<0.05) seems to be statistically significant for the association between the suggested theme and the methodological similarities of the scientific information available in the analyzed databases. Thus, these open-access research tools are considered scientific reliable tools.

关键词： Suicide Physicians Public Health Databases Scientific Communication and Disclosure

SC Hemoglobinopathy(HbSC) with Osteoarticular Complications:Case Report

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Health 2017年第7期9卷 1075-1080页

作者： Filipe Bezerra Macedo jucier goncalves júnior Fabiana Gouveia Guimaraes Raphael Cisne Tomaz Débora Valentim Monte Alto Paula Pessoa Pinheiro jácia Maria Neves Coelho Department of Pediatric Hospital Maternidade Sao Vicente de Paulo(HMSVP)BarbalhaBrazil School of Medicine Federal University of Cariri(UFCA)BarbalhaBrazil Residence in Pediatrics Federal University of Cariri(UFCA)BarbalhaBrazil

Background: Among hemoglobinopathies, the most prevalent in our population are hemoglobins S and C, which are capable of producing disease when homozygous. In cases of double heterozygotes with sickle hemoglobin C (SC), the disease is less expressive in its clinical condition and rarer. Case report: Patient has a previous hospitalization with pain in the joints in knee and hip and several febrile peaks. Upon physical examination, the patient had difficulty in walking, without edema, pedal and tibial posterior pulses present, with no signs of compartment syndrome. Complementary exams revealed anemia, leukocytosis and lymphopenia. The hemoglobin electrophoresis showed the SC Hemoglobinopathy. The treatment with antibiotic therapy according to the protocol (Oxacillin and Ceftriaxone) was restarted and submitted to joint drainage in affected limb. Conclusion: Osteomyelitis and septic arthritis in patients in the pediatric age group should be considered as serious infections that deserve hospitalization and more expressive treatment.

关键词： SC Hemoglobinopathy Paediatrics Case Report

Cryptococcal Meningitis in Patient with Chronic Myeloid Leukemia

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Health 2018年第10期10卷 1349-1356页

作者： Ricardo Parente Garcia Vieira jucier goncalves júnior Acácio Vieira Machado Leite Viviane Chaves Pereira Nélio Barreto Vieira Modesto Leite Rolim-Neto School of Medicine Universidade Federal do CaririBarbalhaBrazil Medical Residency Program in Internal Medicine Santa Casa de Misericórdia de FortalezaFortalezaBrazil

Objective: This study aimed to report the case of a female patient with chronic myeloid leukemia affected by cryptococcal meningitis. Case report: ML, white, 48 years old, female sex, previously diagnosed with chronic myeloid leukemia that has been refractive to the use of imatinib and who has recently begun using nilotinib, was admitted complaining of sudden and disabling migraine in the last 1 month associated with asthenia, adinamia, anorexia, disinterest for daily activities, dizziness, nausea, and vomiting. She evolved with ataxia, and started to stroll with help and showed decrease of muscular strength in her upper limbs. She also presented episodes of decrease of consciousness, with look fixation, no respond to sound stimulation, and short-term hearing loss. The cerebrospinal fluid showed presence of Cryptococcus sp. and, therefore, we began treatment with intravenous liposomal amphotericin B in the dose of 3 mg/kg/day, for 6 weeks. A new cerebrospinal fluid analysis, at the end of treatment, also showed rare structures that are compatible with Cryptococcus sp. As sequelae, she continued with hearing loss in her right ear and enhancement in her right auditory canal, seen in the magnetic resonance imaging. After stabilization and clinical improvement, she was discharged. After 3 weeks, she was hospitalized again with degeneration of the condition, and died due to intracranial hypertension secondary to cryptococcal infection. Final Considerations: This report reinforces the need of reflecting on fungi pathologies, especially in immunosuppressant patients, as well as the importance of early diagnosing and making a fast intervention, with the aims of providing quality of life and comfort to the patient and of minimizing neurological sequelae to the patient.

关键词： Meningitis Cryptococcal Leukemia Myelogenous Chronic Case Reports