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符号互动理论视域下幼儿园灾害教育的理论依据、问题及促进策略

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齐齐哈尔高等师范专科学校学报 2024年第4期 12-16页

作者：刘永春马文华王萌四川幼儿师范高等专科学校四川绵阳621000

依据符号互动理论的基本观点,幼儿园灾害教育的实质是赋予幼儿园灾害教育中的象征性事物以意义,幼儿通过这些被赋予意义的符号进行相互作用与联系,并在这个过程中去运用和修改灾害符号对他的意义。幼儿园利用符号进行灾害教育活动不仅... 详细信息

依据符号互动理论的基本观点,幼儿园灾害教育的实质是赋予幼儿园灾害教育中的象征性事物以意义,幼儿通过这些被赋予意义的符号进行相互作用与联系,并在这个过程中去运用和修改灾害符号对他的意义。幼儿园利用符号进行灾害教育活动不仅可以节约时间和经济成本,避免给幼儿带来不必要的灾害风险,而且可以培养幼儿应对灾害反应的灵活性和变通性。但是,在实际的幼儿园实践过程中却存在符号互动脱离真实灾害反应,缺乏对符号外延的理解以及忽视对灾害符号的回顾等不足。针对这些问题,本文主要提出了回归灾害符号的本真意义,重视灾害符号互动的体验性,构建“计划—活动—回顾”的符号互动模式等应对策略。

关键词：幼儿园符号互动理论灾害教育

系统性硬化患者间质性肺病发生及进展的影响因素分析

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浙江医学 2024年第17期46卷 1830-1834,1839页

作者：刘娟张瑾俞秋霞刘冰冰刘伟丽王晓东丁健宁波市医疗中心李惠利医院(宁波大学附属李惠利医院)风湿免疫科 315040

目的探讨系统性硬化(SSc)发生间质性肺病(ILD)以及出现进展性肺纤维化(PPF)的临床特点和影响因素。方法回顾性收集2017年1月至2021年12月宁波市医疗中心李惠利医院风湿科门诊收治的75例SSc患者为研究对象。根据是否合并ILD,将患者分为SS... 详细信息

目的探讨系统性硬化(SSc)发生间质性肺病(ILD)以及出现进展性肺纤维化(PPF)的临床特点和影响因素。方法回顾性收集2017年1月至2021年12月宁波市医疗中心李惠利医院风湿科门诊收治的75例SSc患者为研究对象。根据是否合并ILD,将患者分为SSc合并ILD(SSc-ILD)组41例和SSc未合并ILD(SSc-nILD)组34例。采用单因素和多因素logistic回归分析SSc患者发生ILD的影响因素。采用单因素logistic回归分析SSc-ILD进展为PPF的影响因素。以肺部高分辨率CT诊断ILD为观察起点,出现PPF为观察终点,绘制Kaplan-Meier生存曲线,采用log-rank检验比较抗Scl-70抗体(ATA)阳性组和ATA阴性组患者发生PPF的中位时间。结果SSc-ILD组患者病程长于SSc-nILD组,弥漫型SSc比例、指/趾端溃疡和(或)凹陷性瘢痕、胃食管反流、肺动脉高压发生率、修订Rodnan评分、ATA阳性率均高于SSc-nILD组,抗着丝点抗体(ACA)阳性率低于SScnILD组,差异均有统计学意义(均P<0.05)。多因素logistic回归分析发现,病程长是SSc患者发生ILD的独立危险因素(OR=1.017,95%CI:1.005~1.029,P=0.005),而ACA是SSc患者发生ILD的独立保护因素(OR=0.102,95%CI:0.017~0.621,P=0.013)。41例SSc-ILD患者中,进展为PPF(PPF组)11例,未进展为PPF(nPPF组)30例。PPF组和nPPF组患者ATA阳性率比较,差异有统计学意义(P<0.05)。单因素logistic回归分析发现ATA阳性是SSc-ILD进展为PPF的危险因素(OR=5.330,95%CI:1.156~24.598,P=0.032)。将PPF患者进一步分为ATA阳性组8例和ATA阴性组3例,进行生存分析,结果显示ATA阳性组患者发生PPF的中位时间为12.0(95%CI:6.8~17.2)个月,明显短于ATA阴性组的48.0(95%CI:37.5~58.5)个月,两组比较差异有统计学意义(P=0.033)。结论长病程可以作为SSc发生ILD的影响因素,而ATA阳性可以作为SSc-ILD患者出现PPF的影响因素。

关键词：系统性硬化间质性肺病进展性肺纤维化临床特点影响因素

Improving aircraft aerodynamic performance with bionic wing obtained by ice shape modulation

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Chinese Journal of Aeronautics 2023年第2期36卷 76-86页

作者： Like XIE hua LIANG Haohua ZONG Yun WU Yinghong LI Zhi SU Xuecheng liu Science and Technology on Plasma Dynamics Laboratory Air Force Engineering UniversityXi'an 710038China School of Mechanical Engineering Xi'an Jiaotong UniversityXi'an 710049China

For Unmanned Aerial Vehicles(UAVs)with limited electrical power to achieve effectively anti-/de-icing at the leading edge of the wing,a strategy of ice shape modulation was *** simulated ice shape pieces printed by 3D printing technology are mounted on a NACA0012 finite wing model,and its lift/drag coefficients and suction-side velocity fields are measured by the six-component force balance and the Particle Imaging Velocimetry(PIV),*** ratio of the spanwise length of a single ice shape piece to chord length and the spanwise length of the non-icing area between the two adjacent single ice shape pieces are defined as dimensionless ice shape length(w/c)and dimensionless modulation ratio(w/λ),*** results indicate that for a fixed w/λ,the wing lift coefficient first increases and then drops with increasing w/c,and a peak value exists when w/c is between 0.1 and *** lower the w/λis,the higher the wing lift coefficient will *** periodical variation of the flow separation area along the spanwise direction is attributed on the one hand to the acceleration effect of the flow field in the non-icing area which reduces the separation area,and on the other hand to the cross-flow caused by the streamwise vortices from the non-icing area to the icing area which promotes the mixing of the flow field(similar to vortex generators).The obtained modulation law is verified through flight tests and provides guidance for the use of ice shape modulation scheme for UAVs that cannot be completely anti-/deicing under severe weather conditions.

关键词： Dimensionless ice shape length Dimensionless modulation ratio Ice shape modulation NACA0012 finite wing Particle imaging velocimetry(PIV) Unmanned aerial vehicles(UAVs)

A Regularized LSTM Method for Predicting Remaining Useful Life of Rolling Bearings

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International Journal of Automation and computing 2021年第4期18卷 581-593页

作者： Zhao-hua liu Xu-Dong Meng hua-Liang Wei Liang Chen Bi-Liang Lu Zhen-Heng Wang Lei Chen School of Information and Electrical Engineering Hunan University of Science and TechnologyXiangtan 411201China Department of Automatic Control and Systems Engineering University of SheffieldSheffield SI 3JDUK

Rotating machinery is important to industrial production. Any failure of rotating machinery, especially the failure of rolling bearings, can lead to equipment shutdown and even more serious incidents. Therefore, accurate residual life prediction plays a crucial role in guaranteeing machine operation safety and reliability and reducing maintenance cost. In order to increase the forecasting precision of the remaining useful life(RUL) of the rolling bearing, an advanced approach combining elastic net with long short-time memory network(LSTM) is proposed, and the new approach is referred to as E-LSTM. The E-LSTM algorithm consists of an elastic mesh and LSTM, taking temporal-spatial correlation into consideration to forecast the RUL through the LSTM. To solve the over-fitting problem of the LSTM neural network during the training process, the elastic net based regularization term is introduced to the LSTM *** this way, the change of the output can be well characterized to express the bearing degradation mode. Experimental results from the real-world data demonstrate that the proposed E-LSTM method can obtain higher stability and relevant values that are useful for the RUL forecasting of bearing. Furthermore, these results also indicate that E-LSTM can achieve better performance.

关键词： Deep learning fault diagnosis fault prognosis long and short time memory network(LSTM) rolling bearing rotating machinery regularization remaining useful life prediction(RUL) recurrent neural network(RNN)

Anti-asthma effects of synthetic salidroside through regulation of Th1/Th2 balance

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Chinese Journal of Natural Medicines 2014年第7期12卷 500-504页

作者： WANG Jing JIN Rong-Guang XIAO Lu WANG Qiu-juan YAN Tian-hua Department of Physiology and Pharmacology China Pharmaceutical University

AIM: The aim of the study was to investigate the effect and mechanism of action of synthetic salidroside in an ovalbumin(OVA)-induced asthma model in mice. METHOD: BALB/c mice were sensitized with an intraperitoneal injection of ovalbumin(OVA) to induce a mouse model of asthma in paracmasis. The mice were treated with dexamethasone as the positive control. At the end of the study, respiratory reactivity was detected, the numbers of various kinds of white blood cells in the bronchoalveolar lavage fluid(BALF) were counted, and the levels of IL-4 and INF-γ in BALF were determined. Quantitative PCR was used to detect the mRNA contents of IL-4 and INF-γ in lung tissue. Histologic examination was performed to observe inflammatory cellular infiltration. RESULTS: Salidroside treatment virtually eliminated airway hyper-reactivity, markedly reduced the eosinophil percent, obviously reduced the levels of IL-4 and raised INF-γ in the bronchoalveolar lavage fluid(BALF) compared with the sham-treated group. Quantitative PCR on the mRNA content of IL-4 and INF-γ provided confirmation. Lung histologic observations showed that salidroside reduced inflammation and edema. These effects were equivalent to the effects of dexamethasone. CONCLUSION: Synthetic salidroside exhibits an anti-asthma effect which is related to the regulation of Th1/Th2 balance. This provides a new possibility for treatment of allergic asthma.

关键词： Synthetic salidroside Asthma Th1/Th2

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肥胖对肺功能影响的研究进展

中华肥胖与代谢病电子杂志 2024年第1期10卷 58-65页

作者：周泽恺刘宝胤聂云韬孟化首都医科大学第八临床医学院北京100038 中日友好医院普外科·代谢减重中心北京100029

肥胖的患病率不断增加，作为多种呼吸系统疾病的危险因素，肥胖患者呼吸系统的结构发生了显著改变，肺功能多项指标异常。本文综述了肥胖对呼吸系统正常结构以及对肺功能常用参数的影响，并讨论了其病理生理学机制。

关键词：肥胖肺功能呼吸系统减重手术支气管哮喘

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我国医院数据安全现状调查分析

医学信息学杂志 2024年第5期45卷 71-75页

作者：郑攀刘华琚文胜陈臣马扬北京市卫生健康大数据与政策研究中心北京100034 中国医院协会信息管理专业委员会北京100027 北京数字认证股份有限公司北京100080

目的/意义通过调研和分析了解全国医疗行业数据安全现状,为监管部门、医院信息化从业人员、医院信息化厂商提供数据安全建设建议。方法/过程面向全国医院信息技术部门负责人及数据安全建设、维护等相关管理人员开展医疗行业数据安全调... 详细信息

目的/意义通过调研和分析了解全国医疗行业数据安全现状,为监管部门、医院信息化从业人员、医院信息化厂商提供数据安全建设建议。方法/过程面向全国医院信息技术部门负责人及数据安全建设、维护等相关管理人员开展医疗行业数据安全调查研究,内容包括对法律法规的了解程度以及医院数据安全建设现状、存在问题、系统功能、分级评估等方面,进而分析全国医疗行业数据安全现状。结果/结论全国医院数据合规意识明显加强,绝大多数医院已具备一定的数据安全技术保障能力,但在数据安全与个人信息保护方面仍存在诸多不足。

关键词：医院信息化数据安全法律法规

Coordination Polymers with Bipyridyl Diene and Triene Ligands:Synthesis,Structures and Luminescent Properties

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Chemical Research in Chinese Universities 2022年第1期38卷 209-216页

作者： hua Chen YI Pin liu Wencong WANG Mengfan NIU Zheng LANG Jianping College of Chemistry Chemical Engineering and Materials ScienceSoochow UniversitySuzhou 215123P.R.China

Solvothermal reactions of cadmium salts with bipyridyl diene and triene ligands[1,3-bis((E)-2-(pyridin-4-yl)vinyl)benzene-(1,3-bpeb) and 1,6-bis(4-pyridyl)-1,3,5-hexatriene(bphte)] and one bipyridyl triene ligand[1,6-bis(4-pyridyl)-1,3,5-hexatriene-(bphte)] in the presence of auxiliary carboxylic acids including 2,6-dichlorobenzoic acid(2,6-HDCBA) and 2-naphthal-enecarboxylic acid(2-HNCA) gave rise to four coordination polymers[Cd(bphte)(2,6-DCBA)2]n(1), {[Cd(bphte)(2-NCA)2]·5.8H2O}n(2),[Cd2(1,3-bpeb)2(2,6-DCBA)4]n(3) and {[Cd4(1,3-bpeb)4(2-NCA)7(HCOO)]·2-HNCA·H2O}n(4), respectively. Compounds 1-4 were structurally characterized by elemental analysis, IR, 1H NMR, powder X-ray diffraction, thermogravimetric analysis and single-crystal X-ray diffraction. They possess one-dimensional linear(1, 2) and zigzag(3, 4) chain structures. Their luminescent properties were explored while the representative sample 4 exhibited good luminescent performance in sensing Fe(III) in water.

关键词： Coordination polymer Bipyridyl olefinic ligand Crystal structure Luminescent property

Acute pancreatitis-induced thrombotic thrombocytopenic purpura:A case report

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World Journal of Clinical Cases 2022年第12期10卷 3808-3813页

作者： Chun-hua Wang Hai-Feng Jin Wen-Ge liu Ying Guo Zhen liu Department of Gastroenterology The 980^(th) Hospital of the People's Liberation Army Joint Service(Bethune International Peace Hospital)Shijiazhuang 050082Hebei ProvinceChina

BACKGROUND Thrombotic thrombocytopenic purpura(TTP)is a life-threatening but treatable *** pancreatitis is a well-described consequence of TTP,but TTP as a consequence of acute pancreatitis is *** SUMMARY A 32-year-old male developed acute pancreatitis due to a fatty diet and suffered splenectomy 3 years ago due to *** day 4 of his onset of pain the blood examination showed the platelet extremely reduced,bilirubin elevated and creatinine *** clinical suspicion of TTP was made and prompt initiation of plasma exchange was given followed intravenous drip *** 7 sessions of plasm exchange and the laboratory parameters were back to normal and the patient was discharged from the hospital on the 13th day of *** Patients develop acute pancreatitis with no apparent causes for hemolytic anemia and thrombocytopenia,the possibility of TTP should be *** for TTP including plasm exchange should be evaluated as soon as a diagnosis is made.

关键词： Thrombotic thrombocytopenic purpura Acute pancreatitis Case report Plasm exchange Glucocorticoid