检索结果-南通市图书馆

Cable-Driven Parallel Robot Workspace Identification and Optimal Design Based on the Upper Limb Functional Rehabilitation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2022年第2期19卷 390-402页

作者： Ferdaws Ennaiem Abdelbadia Chaker juan sandoval Sami Bennour Abdelfattah Mlika Lotfi Romdhane Said Zeghloul Med Amine Laribi Department of GMSC Pprime Institute CNRSENSMAUniversity of PoitiersUPR 3346PoitiersFrance Mechanical Laboratory of Sousse(LMS) National Engineering School of SousseUniversity of Sousse4000 SousseTunisia American University of Sharjah PO Box 26666SharjahUnited Arab Emirates

An assessment of the human motion repeatability for three selected Activities of Daily Living(ADL)is performed in this *** exercises were prescribed by an occupational therapist for the upper limb *** movement patterns of five participants,recorded using a Qualisys motion capture system,are compared based on the Analysis of Variance(ANOVA)*** survey is motivated by the need to find the appropriate task workspace of a 6-degrees of freedom cable-driven parallel robot for upper limb rehabilitation,which is able to reproduce the three selected *** comparison is performed to justify,whether or not,there is enough similarity between the participants’gestures,and so a single reference trajectory can be adopted as the robot-prescribed *** the results of the comparative study,an optimization process of the sought robot design is carried out,where the structure size and the cable tensions simultaneously minimized.

关键词： Human motion repeatability Activities of Daily Living(ADL) Analysis of Variance(ANOVA) Task workspace Cable-driven parallel robot Upper limb rehabilitation Optimization

Protein phosphatases and chromatin modifying complexes in the inflammatory cascade in acute pancreatitis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Pharmacology and Therapeutics 2010年第3期1卷 75-80页

作者： Javier Escobar Javier Pereda Alessandro Arduini juan Sastre juan sandoval Luis Aparisi Gerardo López-Rodas Luis Sabater Department of Physiology University of Valencia 46100 Burjasot (Valencia) Spain Department of Biochemistry & Molecular Biology University of Valencia 46100 Burjasot (Valencia) Spain Laboratory of Pancreatic Function University Clinic Hospital 46010 Valencia Spain Department of Surgery University Clinic Hospital 46010 Valencia Spain

Acute pancreatitis is an inflammation of the pancreas that may lead to systemic inflammatory response syndrome and death due to multiple organ failure. Acinar cells, together with leukocytes, trigger the inflammatory cascade in response to local damage of the pancreas. Amplification of the inflammatory cascade requires up-regulation of proinflammatory cytokines and this process is mediated not only by nuclear factor κB but also by chromatinmodifying complexes and chromatin remodeling. Among the different families of histone acetyltransferases, the p300/CBP family seems to be particularly associated with the inflammatory process. cAMP activates gene expression via the cAMP-responsive element (CRE) and the transcription factor CRE-binding protein (CREB). CREB can be phosphorylated and activated by different kinases, such as protein kinase A and MAPK, and then it recruits the histone acetyltransferase co-activator CREB-binding protein (CBP) and its homologue p300. The recruitment of CBP/p300 and changes in the level of histone acetylation are required for transcription activation. Transcriptional repression is also a dynamic and essential mechanism of down-regulation of genes for resolution of inflammation, which seems to be mediated mainly by protein phosphatases (PP1, PP2A and MKP1) and histone deacetylases(HDACs) .Class HDACs are key transcriptional regulators whose activities are controlled via phosphorylationdependent nucleo/cytoplasmic shuttling. PP2A is responsible for dephosphorylation of class HDACs, triggeringnuclear localization and repression of target genes, whereas phosphorylation triggers cytoplasmic localization leading to activation of target genes. The potential benefit from treatment with phosphodiesterase inhibitors and histone deacetylase inhibitors is discussed.

关键词： Dual specificity protein phosphatases Acute pancreatitis Phosphodiesterase inhibitors Cytokines Histone acetylation Pentoxifylline PP2A Serine/threonine protein phosphatases

Eucalyptus grandis plantations:effects of management on soil carbon,nutrient contents and yields

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Forestry Research 2020年第2期31卷 601-611页

作者： Diego Martin sandoval Lopez Marcelo Fabian Arturi juan Francisco Goya Carolina Alejandra Perez Jorge Luis Frangi Laboratorio de Investigacion de Sistemas Ecologicos y Ambientales(LISEA) Universidad Nacional de La PlataDiagonal 113 N°4691900 La PlataBuenos AiresArgentina

The expansion of fast-growing tree plantations is a worldwide process,with consequences on soil fertility and soil carbon *** results were found on the effects of afforestation with Eucalyptus on soil carbon and other nutrient *** discrepancies are usually caused by differences in climate,land use history,soil texture as well as by management related factors such as plantation age,number of rotations,method of establishment(plantation or coppice),harvest residue management and soil *** studied the effect of plantation age,number of rotations,and method of establishment on soils and plant nutrient concentrations in Eucalyptus grandis plantations in NE Argentina on different textured *** also determined if yields changed with nutrient variations in soils,and compared soils under plantations to soils under grasslands they ***-one *** stands of different ages,number of rotations and method of establishment were evaluated as well as eight grassland *** of carbon,nitrogen,phosphorus,potassium,calcium and magnesium were determined for soils and *** carbon and nitrogen decreased over the number of rotations and were more pronounced in soils with 50-60%sand than soils with>75%*** stands showed higher soil carbon and nitrogen levels than plantations,suggesting a negative effect of site preparation before planting on soil nutrient conservation,especially in fine-textured *** nutrient concentrations did not follow the trends observed for soil nutrients nor did they reflect nutrient *** was no evidence of decreased yields over successive *** carbon and nitrogen contents decrease when grasslands are replaced by *** plantations,and therefore a yield limitation may occur in a medium to long-term frame,especially in stands re-established for short-rotation *** residue management and site preparation must be specifically designed for improving so

关键词： Soil texture Grasslands Foliar nutrient concentrations Successive harvest Coppice Eucalyptus grandis

Experimental determination and modeling of equilibrium moisture content from the sapwood of Mexican pine (Pinus pseudostrobus Lindl.)

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Forestry Studies in China 2011年第4期13卷 285-289页

作者： juan RODRIGUEZ-RAMIREZ Sadoth sandoval-TORRES Lilia MENDEZ-LAGUNAS Artemio Carrillo PARRA Centro Interdisciplinario de Investigación para el Desarrollo Integral Regional (CIIDIR) Oaxaca Instituto Politécnico Nacional Oaxaca 71230 Mexico Facultad de Ciencias Forestales Universidad Autónoma de Nuevo León Linares Nuevo León 67700 Mexico

A desorption isotherm is a very important basis in the understanding of drying process. In this study, the desorption isotherms from the sapwood of Mexican pine （Pinus pseudostrobus Lindl.） were determined by the gravimetric method （discontinuous control of sample weight） at 30℃ and 50℃. The salt method was used in the range of water activities from 0.11 to 0.89. The results show that the desorption ability of Mexican pine sapwood increased with temperature at a given relative humidity. The experimental data was further simulated with the models, i.e., BET, GAB, Oswin and Henderson models. The GAB, Oswin and Henderson models allow the representation of the entire desorption isotherms. The BET model showed a better fit for water activity lower than 0.35, with a mean relative deviation of 0.0286 at 30℃ and 0.0167 at 50℃. Simultaneously, the BET model gave a better representation of moisture content in the monolayer saturation region. Overall, the GAB model ensured the best simulation of the entire isotherm, while the Henderson model displayed the worst simulation.

关键词： modeling isotherms Mexican pine sapwood

Gingival enlargement induced by cyclosporine in Medullary aplasia:A case report

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第34期10卷 12750-12760页

作者： Giovanna Victory Rodríguez Alondra del Carmen Ruiz Gutiérrez juan Ramón Gómez sandoval Sarah Monserrat LomelíMartínez Periodontics Program Department of Integrated Dentistry ClinicsCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340JaliscoMexico Research Institute of Dentistry Department of Integrated Dentistry ClinicsCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340JaliscoMexico Department of Medical and Life Sciences Centro Universitario de la CiénegaUniversidad de GuadalajaraOcotlán 47810JaliscoMexico

BACKGROUND Cyclosporine is an immunosuppressive agent used effectively for treatment of a rare haematological disorder known as medullary *** drug prevents several side effects,including gingival enlargement(GE)which compromises aesthetics,phonetics and chewing,and also predisposes patients to *** SUMMARY This clinical case reports a 41-year-old woman who presented with cyclosporineinduced GE with underlying periodontitis and medullary *** management of the disease was approached through multidisciplinary strategy which allowed for accurate diagnosis and a strategic treatment based on the systemic condition and severity of oral *** diagnosis was confirmed through histopathological *** treatment was carried out in phases:Initial(oral hygiene motivation,mechanical supragingival plaque control,and non-surgical therapy);systemic treatment,corrective treatment,and *** Multidisciplinary management of cyclosporine-induced GE and medullary aplasia allows for correct diagnosis and effective treatment of this pathological expression through a phased therapeutic approach.

关键词： Cyclosporine Gingival enlargement Medullary aplasia Periodontal surgery Case report

Unusual clinical presentation of oral pyogenic granuloma with severe alveolar bone loss:A case report and review of literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第16期11卷 3907-3914页

作者： Sarah Monserrat LomelíMartínez Dennisse Bocanegra Morando Ana Esther Mercado González juan Ramón Gómez sandoval Department of Medical and Life Sciences Centro Universitario de la CiénegaUniversidad de GuadalajaraOcotlán 47810Mexico Master of Public Health Department of Wellbeing and Sustainable DevelopmentCentro Universitario del NorteUniversidad de GuadalajaraColotlán 46200Mexico Periodontics Program Department of Integrated Dentistry ClinicsCentro Universitario de Ciencias de la SaludGuadalajara 44340Mexico Antiguo Hospital Civil de Guadalajara“Fray Antonio Alcalde” Guadalajara 44280Mexico Research Institute of Dentistry Department of Integrated Dentistry ClinicsCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340Mexico

BACKGROUND Pyogenic granuloma(PG)is a localized,reddish and vascularized hyperplastic lesion of the connective tissue which occurs in the oral *** most cases,the presence of this lesion does not show alveolar bone *** pathology is diagnosed clinically with some ***,the diagnosis and treatment are usually corroborated with histopathological *** SUMMARY Three clinical cases of PG associated with bone loss were described in this *** three patients presented tumor-like growth which bled on touch,and were associated with local irritant *** showed bone *** cases were treated with conservative surgical *** scarring was satisfactory,and there was no case of *** diagnoses were based on clinical findings,and were confirmed *** The occurrence of oral PG with bone loss is ***,clinical and radiographic evaluations are important for the diagnosis.

关键词： Hyperplastic lesion Pyogenic granuloma Alveolar bone loss Case report

Spatial patterns of distribution and abundance of Harrisia portoricensis,an endangered Caribbean cactus

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Plant Ecology 2013年第6期6卷 489-498页

作者： Julissa Rojas-sandoval Elvia J.Meléndez-Ackerman Department of Biology University of Puerto RicoRío Piedras CampusPO Box 23360San JuanPuerto Rico 00931-3360USA Center for Applied Tropical Ecology and Conservation University of Puerto RicoPO Box 70377San JuanPuerto Rico 00936-8377USA Department of Environmental Sciences College of Natural SciencesUniversity of Puerto RicoPO Box 70377San JuanPuerto Rico 00936-8377USA

Aims The spatial distribution of biotic and abiotic factors may play a dominant role in determining the distribution and abundance of plants in arid and semiarid *** this study,we evaluated how spatial patterns of microhabitat variables and the degree of spatial dependence of these variables influence the distribution and abundance of the endangered cactus Harrisia *** We used geostatistical analyses of five microhabitat variables(*** cover,soil cover and light incidence)and recorded the abundance of *** in 50 permanent plots established across Mona Island,Puerto Rico,by the United States Department of Agriculture Forest Service as part of the Forest Inventory and Analysis(USDA–FIA).We also used partial Mantel tests to evaluate the relationships between microhabitat variables and abundance of ***,controlling for spatial *** findings Abundance of *** showed strong affinities with microhabitat variables related to canopy structure,soil cover and light *** distribution of this cactus species throughout the island was consistent with the spatial variation patterns of these *** general,landscape-level analyses suggested a predictive value of microhabitat traits for the distribution and abundance of this endangered *** sensitive cacti species,wherein abundance may be influenced by similar variables,these types of analyses may be helpful in developing management plans and identifying critical habitats for conservation.

关键词： abundance Caribbean cactus geostatistics Harrisia portoricensis Mona Island spatial correlation spatial distribution

Increased DNA binding activity of NF-κB,STAT-3,SMAD3 and AP-1 in acutely damaged liver

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第37期12卷 5995-6001页

作者： Adriana Salazar-Montes Luis Ruiz-Corro Ana sandoval-Rodriguez Alberto Lopez-Reyes juan Armendariz-Borunda Institute of Molecular Biology in Medicine and Gene Therapy CUCS University of Guadalajara Apdo. Postal 2-123 Guadalajara 44281 Jal Mexico Institute of Molecular Biology in Medicine and Gene Therapy CUCS University of Guadalajara Apdo.Postal 2-123 Guadalajara 44281 Jal Mexico OPD Hospital Civil de Guadalajara Guadalajara Jal Mexico

AIM: To investigate the role of genes and kinetics of specific transcription factors in liver regeneration, and to analyze the gene expression and the activity of some molecules crucially involved in hepatic regeneration. METHODS: USING gel-shift assay and RT-PCR, transcription factors, such as NF-κB, STAT-3, SMAD3 and AP-1, and gene expression of inducible nitric oxide synthase (iNOS), hepatocyte growth factor (HGF) and c-met were analyzed in an animal model of chemically induced hepatectomy. RESULTS: Gene expression of HGF and its receptor c-met peaked at 3 h and 24 h after acute CCl4 intoxi- cation. iNOS expression was only observed from 6 to 48 h. Transcriptional factor NF-κB had an early activation at 30 min after acute liver damage. STAT-3 peaked 3 h post- intoxication, while AP-1 displayed a peak of activation at 48 h. SMAD3 showed a high activity at all analyzed times. CONCLUSION: TNF-α and IL-6 play a central role in hepatic regeneration. These two molecules are responsible for triggering the cascade of events and switch-on of genes involved in cell proliferation, such as growth factors, kinases and cyclins which are direct participants of cell proliferation.

关键词： Hepatic regeneration Transcription factor Gene regulation

Recent trends and technical advancements in biosensors and their emerging applications in food and bioscience

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Bioscience 2022年第3期47卷 1023-1050页

作者： Oluwatosin E.Bankole Deepak Kumar Verma Mónica L.Chávez González juan Guzmán Ceferino Josésandoval-Cortés Cristóbal N.Aguilar Department of Chemical Sciences Faculty of Science and Science EducationAnchor UniversityLagos StateNigeria Agricultural and Food Engineering Department Indian Institute of Technology KharagpurKharagpur721302West BengalIndia Bioprocesses Research Group Food Research DepartmentSchool of ChemistryUniversidad Autonoma de CoahuilaUnidad Saltillo25280CoahuilaMexico Los Ríos Multidisciplinary Academic Division Universidad Juárez Autónoma de TabascoTabascoMexico Department of Analytical Chemistry School of ChemistryUniversidad Autonoma de CoahuilaUnidad Saltillo25280CoahuilaMexico

Biosensor development has recently advanced as a result of their strong and indisputable uses as analytical methods in a variety of sectors,including medicine,food industry,environmental monitoring,metabolism,agriculture,military,and *** popularity of biosensors as devices for a variety of applications may be ascribed to their distinct advantages of fast or rapid analysis,high sensitivity,minimal sample demand and preparation,and no need for the specific skill of operation that traditional analytical procedures *** attempted to update earlier studies in this study by incorporating other materials that have been in use but have received less attention,such as carbon nano-onions(CNOs),metal-organic frameworks(MOFs),and biopolymers for biosensor manufacturing and design based on their unique *** assessment also took into account applicable applications in many *** considerable progress has been made in the application of biosensors,there is still a need for research development and enhancement,particularly in transforming most of the laboratory experiments that have already been published into portable on-site and implementable in the public domains.

关键词： Biosensors Nanotechnology Nano-materials Food quality and safety Food snd biomedical industry Industrial application