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Collaborative learning via social computing

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Frontiers of Information Technology & Electronic Engineering 2019年第2期20卷 265-282页

作者： Ricardo S.ALONSO Javier PRIETO óscar GARCíA juan m.CORCHADO BISITE Research Group University of Salamanca

Educational innovation is a field that has been greatly enriched by using technology in its processes, resulting in a learning model where information comes from numerous sources and collaboration takes place among multiple students. One attractive challenge within educational innovation is the design of collaborative learning activities from the social computing point of view, where collaboration is not limited to student-to-student relationships, but includes student-to-machine interactions. At the same time, there is a great lack of tools that give support to the whole learning process and are not restricted to specific aspects of the educational task. In this paper, we present and evaluate context-aware framework for collaborative learning applications(CAFCLA) as a solution to these problems. CAFCLA is a flexible framework that covers the entire process of developing collaborative learning activities, taking advantage of contextual information and social interactions. Its application in the experimental case study of a collaborative WebQuest within a museum has shown that, among other benefits, the use of social computing improves the learning process, fosters collaboration, enhances relationships, and increases engagement.

关键词： Context-awareness Collaborative learning Social computing Virtual organizations Wireless sensor networks Real time location system

Cholangiocyte anion exchange and biliary bicarbonate excretion

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World Journal of Gastroenterology 2006年第22期12卷 3496-3511页

作者： Jesús m Banales Jesús Prieto juan F medina Laboratory of molecular Genetics Division of Gene Therapy and Hepatology University of Navarra School of MedicineClinica Universitaria and CIMAPamplonaSpain

Primary canalicular bile undergoes a process of fluidization and alkalinization along the biliary tract that is influenced by several factors including hormones, innervation/neuropeptides, and biliary constituents. The excretion of bicarbonate at both the canaliculi and the bile ducts is an important contributor to the generation of the so-called bile-salt independent flow. Bicarbonate is secreted from hepatocytes and cholangiocytes through parallel mechanisms which involve chloride efflux through activation of Cl- channels, and further bicarbonate secretion via AE2/SLC4A2-mediated Cl-/HCO3- exchange. Glucagon and secretin are two relevant hormones which seem to act very similarly in their target cells （hepatocytes for the former and cholangiocytes for the latter）. These hormones interact with their specific G protein-coupled receptors, causing increases in intracellular levels of cAmP and activation of cAmP-dependent Cl- and HCO3- secretory mechanisms. Both hepatocytes and cholangiocytes appear to have cAmP-responsive intracellular vesicles in which AE2/SLC4A2 colocalizes with cell specific Cl- channels （CFTR in cholangiocytes and not yet determined in hepatocytes） and aquaporins （AQP8 in hepatocytes and AQP1 in cholangiocytes）, cAmP-induced coordinated trafficking of these vesicles to either canalicular or cholangiocyte lumenal membranes and further exocytosis results in increased osmotic forces and passive movement of water with net bicarbonate-rich hydrocholeresis.

关键词： AE2 anion exchanger Bile salt-independent flow Biliary bicarbonate excretion Regulation of intracellular pH Hydroionic fluxes in cholangiocytes

A NETWORK ANALYSIS OF THE 2010 FIFA WORLD CUP CHAmPION TEAm PLAY

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Journal of Systems Science & Complexity 2013年第1期26卷 21-42页

作者： COTTA Carlos mORA Antonio m mERELO juan Julin mERELO-mOLINA Cecilia Department of Computer Science University of Mlaga Department of Architecture and Computer Technology University of Granada

This paper analyzes the network of passes among the players of the Spanish team during the last FIFA World Cup 2010,where they emerged as the champion,with the objective of explaining the results obtained from the behavior at the complex network *** team is considered a network with players as nodes and passes as(directed) edges.A temporal analysis of the resulting passes network is also done,looking at the number of passes,length of the chain of passes,and to network measures such as player centrality and clustering *** of the last three matches(the decisive ones) indicate that the clustering coefficient of the pass network remains high,indicating the elaborate style of the Spanish *** effectiveness of the opposing team in negating the Spanish game is reflected in the change of several network measures over time,most importantly in drops of the clustering coefficient and passing length/speed,as well as in their being able in removing the most talented players from the central positions of the ***'s ability to restore their combinative game and move the focus of the game to offensive positions and talented players is shown to tilt the balance in favor of the Spanish team.

关键词： Complex network complex systems FIFA World Cup football La Roja network analysis soccer Spanish team sports.

Plateau archives of lithosphere dynamics,cryosphere and paleoclimate:The formation of Cretaceous desert basins in east Asia

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Geoscience Frontiers 2022年第6期13卷 170-181页

作者： Chihua Wu juan Pedro Rodríguez-López m.Santosh State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of TechnologyChengdu 610059China PAGODA Research Group(Plateau&Global Desert Basins Research Group) Institute of Sedimentary GeologyChengdu University of TechnologyChengdu 610059China Permafrost Laboratory Department of GeographyUniversity of SussexFalmerBrighton BN19SJUnited Kingdom School of Earth Science and Resources China University of Geosciences29 Xueyuan RoadBeijing 100083China Department of Earth Sciences University of AdelaideSA 5005Australia

Southeastern Eurasia is a global window to the Cretaceous paleoclimate and lithosphere *** contains one of the most complete and complex sedimentary records of mesozoic desert basins on planet *** this study,we perform the spatio-temporal tracking of 96 Cretaceous palaeoclimate indicators during 79 myr which reveal that the plateau paleoclimate archives from East Asia resulted from an Early to mid-Cretaceous ocean–atmosphere coupling and a shift to a preponderant role of Late Cretaceous lithosphere dynamics and tectonic forcing on high-altitude depositional systems linked to the subduction margins of the Tethys and Paleo-Pacific realms beneath the Eurasian *** crustal response to tectonic processes linked with the spatio-temporal evolution of the Tethyan and Paleo-Pacific margins defined the configuration of major sedimentary basins on this *** significant increase and decrease in the number of active sedimentary basins that occur during the Cretaceous,from 16 in the Early Cretaceous,to 28 in the mid-Cretaceous,and a decreasing to 20 sedimentary basins in the Late Cretaceous,is a direct response of lithospheric dynamics associated with the two main subduction zones(Tethys and Pacific domains).A shift in subduction style from an Early Cretaceous Paleo-Pacific Plate slab roll back to a Late Cretaceous flat-slab mode might have triggered regional plateau uplift,blocked intraplate volcanism,thus enhancing the denudation and sediment availability,and created wind corridors that led to the construction and accumulation of extensive Late Cretaceous aeolian sandy deserts(ergs)that covered mid-Cretaceous plateau *** the same time,plateau uplift associated with crustal thickening following terrane assembly in the Tethyan margin triggered altitudinal cryospheric processes in sandy desert *** of an active Cretaceous cryosphere in China include ValanginianHauterivian glacial debris flows,Early Aptian geochemical signature of melt w

关键词： Cretaceous Cryosphere Aeolian Plateau Subduction Asia

Canine Herpesvirus Seroprevalence and Associated Factors in Dogs of mexico

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Open Journal of Veterinary medicine 2016年第10期6卷 149-162页

作者： Edgar Guillermo valdivia Lara Jesica Ileana Ángeles Solis Cesar Cuenca Verde juan Antonio montaraz Crespo Laura Cobos marín juan Carlos Del Río García Guillermo valdivia Anda Laboratorio de Patogenicidad microbiana Unidad de Investigación Multidisciplinaria Facultad de Estudios Superiores Cuautitlán Universidad Nacional Autónoma de México Cuautitlan Izcalli México Laboratorio de Inmunología Facultad de Estudios Superiores Cuautitlán Universidad Nacional Autónoma de México Ciudad de México México Facultad de medicina Veterinaria Universidad Nacional Autónoma de México Ciudad Universitaria Ciudad de México México Laboratorio de micotoxinas Unidad de Investigación Multidisciplinaria Facultad de Estudios Superiores Cuautitlán Universidad Nacional Autónoma de México Ciudad de México México

Canine herpesvirus (CHV-1) causes disease associated with high mortality in infect-ed puppies, which represents large financial losses for dog breeders. Since CHV-1 at the time of the study he had not been reported in mexico, the main objective of this study was to determine the prevalence of antibodies against CHV-1 in canine kennels in the metropolitan area of mexico City. A commercial enzyme-linked immuno-sorbent assay (ELISA) was used, and the results were compared to those of a viral neutralization test. The ELISA kit uses the complete viral particle as the antigen. The plaque reduction neutralization test was combined with the immunoperoxidase technique because of the low cytopathic effect of CHV-1. Neutralizing antibodies were also detected in 20 randomly selected samples. The prevalence of CHV-1 with ELISA was 87%. The concordance between ELISA and serum neutralization (SN) was 0.1129, the sensitivity of the ELISA against SN was 1.0 (100%), the positive predic-tive value was 0.39 (39%), and the negative predictive value was 1 (100%). These results show that ELISA is useful for monitoring the dog population for CHV-1;a positive test result requires confirmation with an SN test, and a negative ELISA result indicates a high probability of being SN-negative. The only variables that were sta-tistically associated with CHV-1 prevalence were breed and kennel. A statistically significant relationship between the degree of ELISA and SN titer was obtained, with a confidence level of 95%. None of the clinical presentation factors was statistically significant. These results suggest that most of the canine population studied in mex-ico is in a herpesvirus latency state.

关键词： Canine Herpesvirus Seroprevalence Enzyme-Linked Immunosorbent Assay Serum Neutralization Test

Time for a paradigm shift in the classification of muscle injuries

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Journal of Sport and Health Science 2017年第3期6卷 255-261页

作者： Bruce Hamilton juan-manuel Alonso Thomas m.Best High Performance Sport New Zealand Millennium Institute of Sport and HealthMairangi BayAuckland 0110New Zealand Sports medicine Department Qatar Orthopaedic and Sports Medicine HospitalDoha 22922Qatar UHealth Sports medicine Institute University of Miami Miller School of MedicineMiamiFL 33136USA

muscle injuries remain one of the most common injuries in sport,yet despite this,there is little consensus on how to either effectively describe or determine the prognosis of a specific muscle *** approaches to muscle classification and grading of medicine have been applied over the last century,but over the last decade the limitations of historic approaches have been *** a consequence,in the past 10 years,clinical research groups have begun to question the historic approaches and reconsider the way muscle injuries are classified and *** a narrative approach,this manuscript describes several of the most recent attempts to classify and grade muscle injuries and highlights the relative strengths and weaknesses of each *** each of the new classification and grading systems have strengths,there remains little consensus on a system that is both comprehensive and evidence *** of the currently identified features within the grading systems have relevance to accurately determining prognosis.

关键词： Classification Grading magnetic resonance imaging muscle injury Return to play Ultrasound

Patency and agile capsules

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World Journal of Gastroenterology 2008年第34期14卷 5269-5273页

作者： ngel Caunedo-lvarez Javier Romero-Vazquez juan m Herrerias-Gutierrez Gastroenterology Service "Virgen Macarena" University Hospital

Small bowel strictures can be missed by current diagnostic methods. The Patency capsule is a new non-endoscopic dissolvable capsule which has as an objective of checking the patency of digestive tract, in a non-invasive manner. The available clinical trials have demonstrated that the Patency capsule is a good tool for assessment of the functional patency of the small bowel, and it allows identification of those patients who can safely undergo a capsule endoscopy, despite clinical and radiographic evidence of small-bowel obstruction. Some cases of intestinal occlusion have been reported with the Patency capsule, four of them needed surgery. So, a new capsule with two timer plugs (Agile capsule) has been recently developed in order to minimize the risk of occlusion. This new device stars its dissolution process earlier (30 h after ingestion) and its two timer plugs have been designed to begin the disintegration even when the device is blocked in a tight stricture.

关键词： Capsule endoscopy Patency capsule Agile capsule Small bowel strictures

Charged quark stars in f(R,T)gravity

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Chinese Physics C 2022年第11期46卷 308-317页

作者： juan m.Z.Pretel Takol Tangphati Ayan Banerjee Anirudh Pradhan Centro Brasileiro de Pesquisas Físicas Rua Dr.Xavier Sigaud150 URCARio de Janeiro CEP 22290-180RJBrazil Theoretical and Computational Physics Group Theoretical and Computational Science Center(TaCS)Faculty of ScienceKing Mongkut’s University of Technology Thonburi126 Prachauthid Rd.Bangkok 10140Thailand Astrophysics and Cosmology Research Unit School of MathematicsStatistics and Computer ScienceUniversity of KwaZulu-NatalPrivate Bag X54001Durban 4000South Africa Centre for Cosmology Astrophysics and Space ScienceGLA UniversityMathura-281406Uttar PradeshIndia

Recent advances in nuclear theory and new astrophysical observations have led to the need for specific theoretical models applicable to dense-matter physics *** chromodynamics(QCD)predicts the existence of non-nucleonic degrees of freedom at high densities in neutron-star matter,such as quark *** a confining quark matter model,which consists of homogeneous,neutral 3-flavor interacting quark matter with O(m_(s)^(4))corrections,we examine the structure of compact stars composed of a charged perfect fluid in the context of f(R,T)*** system of differential equations describing the structure of charged compact stars has been derived and numerically solved for a gravity model with f(R,T)=R+2β*** simplicity,we assumed that the charge density is proportional to the energy density,namely,ρ_(ch)=αρ.It is demonstrated that the matter-geometry coupling constant β and charge parameter α affect the total gravitational mass and the radius of the star.

关键词： charged stars f(R T)gravity

Loss of largest and oldest individuals of the montpellier snake correlates with recent warming in the southeastern Iberian Peninsula

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Current Zoology 2017年第6期63卷 607-613页

作者： Cosme LOPEZ-CALDERON monica FERICHE Esmeralda ALAmINOS juan m. PLEGUEZUELOS Department of Zoology Faculty of Biology University of Seville C/Reina Mercedes Seville E-41012 Spain Department of Zoology Faculty of Sciences University of Granada Granada E-18071 Spain

The effects of climate change on organisms are now being extensively studied in many different taxa. However, the variation in body size, usually shrinkage in response to increasing temperature, has received little attention regarding to reptiles. During past periods of global warming, many organisms shrank in size, and current evidence and experiments manipulating temperature have shown a biomass decrease in some organisms with increasing temperatures. Here we test whether the body size of the montpellier snake malpolon rnonspessulanus from the southeastern Iberian Peninsula is changing and correlated with the increasing temperature in this region during a 39- year period （1976-2014）. We measured the snout-vent length （SVL） of vouchers in scientific collections to check for trends in adult body size at the population level in relation with temperature, while controlling for the age of the individuals （estimated by skeletochronology, n =141）. Given the great ontogenetic variation in body size of the study species, we categorized age in 3 classes：＂young adults＂（under 5 years old）, ＂intermediate adults＂（from 5 to 7 years old）, and ＂old adults＂（from 8 to 14 years old）. By means of linear mixed models, we found a negative relationship between SVL of ＂old adults＂ and average annual temperature in the region during the lifetime of each individual. Our results indicate that largest and oldest individuals of the montpellier Snake, that is, males because of strong sexual size dimorphism in this species, disappeared from the study population, and suggest that it occurred in response to rising environmental temperature.

关键词： body shrinkage climate warming differential mortality malpolon monspessulanus skeletochronology snakes Spain.