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Chinese Journal of Aeronautics 2021年第4期34卷 375-386页

作者： Xin XUE Xinyong WU juan liao School of Mechanical Engineering and Automation Fuzhou UniversityFuzhou 350116China Fujian Nebula Electronics Co. Ltd.Fuzhou 350015China

Laser welding of dissimilar titanium/aluminum alloys has been employed at an increasing rate,particularly in the aerospace industry,owing to its advantages in terms of current design flexibility and fuel/cost *** major problem with dissimilar Ti/Al welds arises from the difference in the thermal expansion and contraction of the two metals,which leads to hot-cracking susceptibility and the mitigation of the mechanical property after *** the present study,pulsed Nd:YAG laser welding of Ti6 Al4 V and AA6060 has been ***-cracking susceptibility in the heat affected zone and the shear fracture behavior of the lap joints were investigated through microstructural characterization and mechanical *** results indicate that the hot cracking tendency can be reduced by increasing the pulse peak power(7.5–8.5 kW)and the laser point diameter(0.8–1.0 mm)with specific pulse duration and *** alternative control strategy for less hot cracks in the Ti/Al lap joint can be to increase the weld width and decrease the cooling rate during *** shear fracture of the Ti/Al lap joint is likely to occur along the lower side path of the weld interface with decreasing weld surface collapsed amount and increasing aluminum base metal melt depth.

关键词： Aluminum alloy Hot-cracking susceptibility Pulsed Nd:YAG laser welding Shear fracture behavior Titanium alloy

Thermodynamic property of sandwich cylindrical shell structure with metallic wire mesh:Numerical modeling and experimental analysis

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Chinese Journal of Aeronautics 2024年第1期37卷 138-152页

作者： Xin XUE Guojian SHEN juan liao Institute of Metal Rubber&Vibration Noise School of Mechanical Engineering and AutomationFuzhou UniversityFuzhou 350116China Fujian Shuikou Power Generation Group Co. LTDFuzhou 350000China

As a new addition to lightweight composite structures,the sandwich cylindrical shell with a metallic wire mesh core has emerged as a promising solution for thermodynamic performance analysis at elevated *** intricate interwoven cellular formations within the metallic wire mesh pose difficulties for thermo-mechanical modeling and property ***,the constitutive models employed to characterize hysteresis phenomena were presented,comprising isotropic elasticity,Bergstrom-Boyce model,Ogden hyper-elasticity,and parameter identification through mechanical examinations at varying ***,the finite element modeling of cylindrical shell structures was determined for modal and steady-state dynamic ***,the experimental procedures were carried out,including the preparation of the sandwich cylindrical shell and the dynamic testing *** first-order natural frequency of the cylindrical shell structure is close to the resonance frequency of the dynamic test results,with a maximum error of 6.5%,demonstrating the accuracy of the simulation *** compared to the solid-core cylindrical shell,the average insertion loss of the sandwich cylindrical shell structure within the frequency range of 10–1000 Hz at room temperature is up to 11.09 ***,at elevated temperatures,the average insertion loss of the sandwich cylindrical shell decreases but fluctuates as the temperature changes.

关键词： Energy dissipation Metallic matrix composites Numerical analysis Sandwich structure Thermodynamic properties

Interface property of dissimilar Ti-6Al-4V/AA1050 composite laminate made by non-equal channel lateral co-extrusion and heat treatment

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Defence Technology（防务技术） 2024年第3期33卷 197-208页

作者： juan liao Mengmeng Tian Xin Xue School of Mechanical Engineering and Automation Fuzhou UniversityFuzhou 350116China

The purpose of this paper is to examine the effect of processing parameters and subsequent heat treatments on the microstructures and bonding strengths of Ti-6Al-4V/AA1050 laminations formed via a non-equal channel lateral co-extrusion *** microstructural evolution and growth mechanism in the diffusion layer were discussed further to optimize the bonding quality by appropriately adjusting process *** electron microscopes(SEM),energy dispersive spectrometer(EDS),and X-ray diffraction(XRD)were used to characterize interfacial diffusion *** shear test was used to determine the mechanical properties of the interfacial diffusion *** experimental results indicate that it is possible to co-extrusion Ti-6Al-4V/AA1050 compound profiles using non-equal channel lateral *** heat treatment processes affect the thickness of the diffusion *** the temperature and time of heat treatment increase,the thickness of the reaction layers increases ***,the shear strength of the Ti-6Al-4V/AA1050 composite interface is proportional to the diffusion layer *** is observed that a medium interface thickness results in superior mechanical performance when compared to neither a greater nor a lesser interface *** characterization of all heat treatments reveals that the only intermetallic compound observed in the diffusion layers is TiAl_(3).Due to the inter-diffusion of Ti and Al atoms,the TiAl_(3) layer grows primarily at AA1050/TiAl_(3) interfaces.

关键词： Shear strength Co-extrusion Heat treatment Microstructure Intermetallic compounds

Ribosomal proteins:functions beyond the ribosome

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Journal of Molecular Cell Biology 2015年第2期7卷 92-104页

作者： Xiang Zhou Wen-juan liao Jun-Ming liao Peng liao Hua Lu Department of Biochemistry&Molecular Biology and Tulane Cancer Center Tulane University School of MedicineNew OrleansLA 70112USA

Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation,their ribosomeindependent functions have also been greatly *** the past decade,more than a dozen of ribosomal proteins have been found to activate the tumor suppressor p53 pathway in response to ribosomal *** addition,these ribosomal proteins are involved in various physiological and pathological *** review is composed to overview the current understanding of how ribosomal stress provokes the accumulation of ribosome-free ribosomal proteins,as well as the ribosome-independent functions of ribosomal proteins in tumorigenesis,immune signaling,and *** propose the potential of applying these pieces of knowledge to the development of ribosomal stress-based cancer therapeutics.

关键词： ribosomal protein ribosomal stress p53 MDM2 cancer immunity ribosomopathy

A hybrid hydrogel based on clay nanoplatelets and host–guest inclusion complexes

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Chinese Chemical Letters 2016年第4期27卷 583-587页

作者： Xiao-juan liao Guo-Song Chen School of Chemistry and Molecular Engineering East China Normal University Shanghai 200241 China State Key Laboratory of Molecular Engineering of Polymers Fudan University Shanghai 200433 China

In this work,a monomer with double bond was introduced to the surface of clay nanosheets via inclusion complexation between cyclodextrin（CD）host and azobenzene（Azo）guest,as well as electrostatic interaction between clay nanoplatelets and cations of azobenzene *** obtained suprastructure acts as a supramolecular cross-linker in its copolymerization with macromonomer PEG resulting in a hybrid supramolecular *** viscous liquid was obtained in the absence of clay nanoplatelets,revealing the supramolecular cross-linker played an important role in the hydrogel *** hybrid supramolecular hydrogel exhibited good stability and shear thinning property.

关键词： Host–guest chemistry Clay Supramolecular hydrogel Cyclodextrin Electrostatic interaction

Convergence and Stability of an Explicit Method for Autonomous Time-Changed Stochastic Differential Equations with Super-Linear Coefficients

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Advances in Applied Mathematics and Mechanics 2023年第3期15卷 651-683页

作者： Xiaotong Li juan liao Wei Liu Zhuo Xing Department of Mathematics Shanghai Normal UniversityShanghai 200234China Lab for Educational Big Data and Policymaking Shanghai Normal UniversityShanghai 200234China

In this paper,numerical methods for the time-changed stochastic differential equations of the form dY(t)=a(Y(t))dt+b(Y(t))dE(t)+s(Y(t))dB(E(t))are investigated,where all the coefficients a(·),b(·)and s(·)are allowed to contain some super-linearly growing *** explicit method is proposed by using the idea of truncating terms that grow too *** convergence in the finite time of the proposed method is proved and the convergence rate is *** proposed method is also proved to be able to reproduce the asymptotic stability of the underlying equation in the almost sure *** are provided to demonstrate the theoretical results.

关键词： Time-changed stochastic differential equations explicit method super-linear coefficients strong convergence asymptotic stability

A Nonparametric Approach to Foreground Detection in Dynamic Backgrounds

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China Communications 2015年第2期12卷 32-39页

作者： liao juan JIANG Dengbiao LI Bo RUAN Yaduan CHEN Qimei Institute of Electronic Science and Engineering Nanjing

Foreground detection is a fundamental step in visual ***,accurate foreground detection is still a challenging task especially in dynamic *** this paper,we present a nonparametric approach to foreground detection in dynamic *** uses a history of recently pixel values to estimate background ***,the adaptive threshold and spatial coherence are introduced to enhance robustness against false *** results indicate that our approach achieves better performance in dynamic backgrounds compared with several approaches.

关键词： foreground detection dynamic background the decision threshold spatial coherence

High-yield synthesis of a novel water-soluble macrocycle for selective recognition of naphthalene

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Chinese Chemical Letters 2021年第5期32卷 1665-1668页

作者： Man-Hua Ding juan liao Lin-Li Tang Guang-Chuan Ou Fei Zeng Department of Biology and Chemistry Hunan University of Science and EngineeringKey Laboratory Comprehensive Utilization of Dominant Plants Resources in South HunanYongzhou 425199China

A novel good water-soluble macrocycle containing two pyridinium moieties was synthesized in high *** could form 1:1 complexes with neutral guests containing naphthalene or phenyl units in *** water-soluble macrocycle ... 详细信息

关键词： Water-soluble Macrocycle Naphthalene Supramolecular chemistry Recog ration

Lodging Resistance Related to Root Traits for Mechanized Wet-Seeding of Two Super Rice Cultivars

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Rice science 2021年第2期28卷 200-208,I0002-I0007页

作者： ZHANG Minghua MO Zhaowen liao juan PAN Shenggang CHEN Xiongfei ZHENG Le LUO Xiwen WANG Zaiman Key Laboratory of Key Technology on Agricultural Machine and Equipment/College of Engineering South China Agricultural UniversityGuangzhou 510642China College of Agriculture South China Agricultural UniversityGuangzhou 510642China School of Engineering Jiangxi Agricultural UniversityNanchang 330045China

Mechanical hill wet-seeded rice machine is beneficial for establishing and growing uniform rows of ***,there is limited knowledge regarding the effects of the establishment of furrows on growth,lodging and yield,and their relationships with root *** this study,field experiments were conducted during 2012 and 2013 using two super rice varieties(hybrid rice Peizataifeng and inbred rice Yuxiangyouzhan)under three furrow establishment treatments(T1,both water and seed furrows were established by the machine;T2,only seed furrows were established by the machine;and T3,neither water nor seed furrows were established by the machine).Lodging index,lodging-related traits,grain yield,above-ground dry weight and root traits were *** results showed that the lodging index was significantly affected by the treatments with furrows(T1 and T2).The strongest lodging resistance was detected in the mechanical hill wet-seeded rice with furrow treatment(T1)in both 2012 and *** resistance was strongly related to the breaking *** significant difference was found in grain yield or dry weight of the mechanical hill wet-seeded ***,the mechanical hill wet-seeded rice with furrow treatment increased rice lodging resistance,which was related to root traits.

关键词： seed furrow grain yield lodging resistance root trait mechanical wet-seeded rice

Silencing Huwe1 reduces apoptosis of cortical neurons exposed to oxygen-glucose deprivation and reperfusion

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Neural Regeneration Research 2019年第11期14卷 1977-1985页

作者： Guo-Qian He Wen-Ming Xu Hui-juan liao Chuan Jiang Chang-Qing Li Wei Zhang Department of Pediatrics Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University)Ministry of EducationWest China Second University HospitalSichuan UniversityChengduSichuan ProvinceChina Joint Laboratory of Reproductive Medicine Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University)Ministry of EducationWest China Second University HospitalSichuan UniversityChengduSichuan ProvinceChina Department of Neurology The Second Affiliated Hospital of Chongqing Medical UniversityChongqingChina Department of Medical Oncology Sichuan Cancer Hospital & InstituteSichuan Cancer CenterCancer Hospital Affiliated to School of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina

HECT, UBA and WWE domain-containing 1(Huwe1), an E3 ubiquitin ligase involved in the ubiquitin-proteasome system, is widely expressed in brain tissue. Huwe1 is involved in the turnover of numerous substrates, including p53, Mcl-1, Cdc6 and N-myc, thereby playing a critical role in apoptosis and neurogenesis. However, the role of Huwe1 in brain ischemia and reperfusion injury remains unclear. Therefore, in this study, we investigated the role of Huwe1 in an in vitro model of ischemia and reperfusion injury. At 3 days in vitro, primary cortical neurons were transduced with a control or shRNA-Huwe1 lentiviral vector to silence expression of Huwe1. At 7 days in vitro, the cells were exposed to oxygen-glucose deprivation for 3 hours and reperfusion for 24 hours. To examine the role of the c-Jun N-terminal kinase(JNK)/p38 pathway, cortical neurons were pretreated with a JNK inhibitor(SP600125) or a p38 MAPK inhibitor(SB203508) for 30 minutes at 7 days in vitro, followed by ischemia and reperfusion. Neuronal apoptosis was assessed by TUNEL assay. Protein expression levels of JNK and p38 MAPK and of apoptosis-related proteins(p53, Gadd45 a, cleaved caspase-3, Bax and Bcl-2) were measured by western blot assay. Immunofluorescence labeling for cleaved caspase-3 was performed. We observed a significant increase in neuronal apoptosis and Huwe1 expression after ischemia and reperfusion. Treatment with the shRNA-Huwe1 lentiviral vector markedly decreased Huwe1 levels, and significantly decreased the number of TUNEL-positive cells after ischemia and reperfusion. The silencing vector also downregulated the pro-apoptotic proteins Bax and cleaved caspase-3, and upregulated the anti-apoptotic proteins Gadd45 a and Bcl-2. Silencing Huwe1 also significantly reduced p-JNK levels and increased p-p38 levels. Our findings show that downregulating Huwe1 affects the JNK and p38 MAPK signaling pathways as well as the expression of apoptosis-related genes to provide neuroprotection during ische

关键词： nerve regeneration ischemic stroke oxygen-glucose deprivation and reperfusion ischemia/reperfusion cortical neuron ubiquitin proteasome system Huwe1 apoptosis therapeutic targets cell culture cell death neural regeneration