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Plant cover as an estimator of above-ground biomass in semi-arid woody vegetation in Northeast Patagonia,Argentina

Journal of Arid Land 2021年第9期13卷 918-933页

作者： Laura B RODRIGUEZ silvia s TORREs ROBLEs Marcelo F ARTURI juan M ZEBERIO Andrés c H GRAND Néstor I GAsPARRI National University of Río Negro Atlantic HeadquartersCenter for Environmental Studies from Norpatagonia(CEANPa)Viedma 8500Argentina National council of scientific and Technical Research(cONIcET) Viedma 8500Argentina Ecological and Environmental systems Research Laboratory(LIsEA) National University of La PlataLa Plata 1900Argentina National Institute of Agricultural Technology(INTA) AER PatagonesCarmen de Patagones 8504Argentina Institute of Regional Ecology(IER) National University of Tucumán(UNT)-National Council of Scientific and Technical Research(CONICET)Tucumán 4000Argentina Faculty of Natural sciences and Miguel Lillo Institute National University of Tucumán(UNT)Yerba Buena 4107Argentina

The quantification of carbon storage in vegetation biomass is a crucial factor in the estimation and mitigation of cO2 ***,arid and semi-arid regions are considered an important carbon ***,they have received limited attention and,therefore,it should be a priority to develop tools to quantify biomass at the local and regional *** plant variables,such as stem diameter and crown area,were reported to be good predictors of individual plant ***-level variables,such as plant cover and mean height,are also easy-to-measure estimators of above-ground biomass(AGB)in dry *** this study,we estimated the AGB in semi-arid woody vegetation in Northeast Patagonia,*** evaluated whether the AGB at the stand level can be estimated based on plant cover and to what extent the estimation accuracy can be improved by the inclusion of other field-measured structure *** also evaluated whether remote sensing technologies can be used to reliably estimate and map the regional mean *** this purpose,we analyzed the relationships between field-measured woody vegetation structure variables and AGB as well as LANDsAT TM-derived *** obtained a model-based ratio estimate of regional mean AGB and its standard *** plant cover allowed us to obtain a reliable estimation of local AGB,and no better fit was attained by the inclusion of other structure *** stand-level plant cover ranged between 18.7%and 95.2%and AGB between about 2.0 and 70.8 Mg/hm^(2).AGB based on total plant cover was well estimated from LANDsAT TM bands 2 and 3,which facilitated a model-based ratio estimate of the regional mean AGB(approximately 12.0 Mg/hm^(2))and its sampling error(about 30.0%).The mean AGB of woody vegetation can greatly contribute to carbon storage in semi-arid ***,plant cover estimation by remote sensing images could be used to obtain regional estimates and map biomass,as well as to assess and monitor the i

关键词： above-ground biomass shrublands ratio estimation carbon storage remote sensing Patagonia

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Diterpenes and the crosstalk with the arachidonic acid pathways, relevance in neurodegeneration

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Neural Regeneration Research 2019年第10期14卷 1705-1706页

作者： juan M. Zolezzi Nibaldo c. Inestrosa centro de Envejecimiento y Regeneración (cARE Uc) Department de Biología Celular y MolecularFacultad de Ciencias BiológicasPontificia Universidad Católica de ChileSantiagoChileCentro de Excelencia en Biomedicina de MagallanesUniversidad de MagallanesPunta ArenasChile centre for Healthy Brain Ageing School of PsychiatryFaculty of MedicineUniversity of New South WalesSydneyAustralia

Dementia has emerged as one of the main threats to human health in the modern civilization. Increased aging of world population and unhealthy lifestyle habits have been identified as critical factors able to facilitate dementia establishment. In this context, according to the Alzheimer’s Research International, Alzheimer’s disease (AD) constitutes the primary cause of dementia worldwide and its numbers are expected to grow during the following years. clinically, AD is characterized by the progressive decline in the cognitive performance as well as by an altered social behavior. Initially affecting the short-term memory, the long-term memory becomes compromised as the pathology progresses.

关键词： Dementia human health in the modern

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益母草碱对结肠癌荷瘤小鼠肿瘤生长和免疫功能的影响

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中国临床药理学杂志 2024年第3期40卷 398-402页

作者：刘建邦黄娟李斌中国人民解放军联勤保障部队第九二〇医院普外科云南昆明650032

目的探讨益母草碱对结肠癌荷瘤小鼠肿瘤生长和免疫功能的影响。方法 c57BL/6小鼠建立结肠癌荷瘤小鼠模型,造模后的小鼠随机分为对照组(0.9%Nacl)、低剂量实验组(180 ng·g^(-1)益母草碱)、高剂量实验组(360 ng·g^(-1)益母草碱)、高剂... 详细信息

目的探讨益母草碱对结肠癌荷瘤小鼠肿瘤生长和免疫功能的影响。方法 c57BL/6小鼠建立结肠癌荷瘤小鼠模型,造模后的小鼠随机分为对照组(0.9%Nacl)、低剂量实验组(180 ng·g^(-1)益母草碱)、高剂量实验组(360 ng·g^(-1)益母草碱)、高剂量+空载组(360 ng·g^(-1)益母草碱+空载质粒)、高剂量+cGAs敲低组(360 ng·g^(-1)+cGAs siRNA质粒)。分组处理后测定肿瘤体积与质量,以免疫组化染色检测肿瘤组织环状GMP-AMP合成酶(cGAs)、干扰素基因刺激因子(sTING)相对阳性表达及cD4^(+)T与cD8^(+)T阳性细胞数,以细胞计数试剂盒8法检测小鼠cD4^(+)T与cD8^(+)T细胞对肿瘤细胞杀伤率。结果对照组、高剂量实验组、高剂量+空载组、高剂量+cGAs敲低组小鼠的肿瘤体积分别为(1 088.32±70.82)、(468.20±24.28)、(480.01±23.78)和(998.99±32.84)mm~3,cGAs相对阳性表达分别为1.00±0.00、5.18±0.73、5.30±0.80和1.12±0.46,sTING相对阳性表达分别为1.00±0.00、5.64±0.81、5.48±0.75和1.14±0.50,cD4^(+)T阳性细胞数分别为(40.25±5.82)、(118.64±15.30)、(113.25±16.65)和(48.74±7.10)个,cD8^(+)T阳性细胞数分别为(49.76±6.12)、(143.68±16.80)、(135.75±17.42)和(57.01±8.24)个。高剂量实验组、高剂量+空载组的上述指标与对照组比较,在统计学上差异均有统计学意义(均PcGAs敲低组的上述指标与高剂量实验组比较,在统计学上差异均有统计学意义(均PcGAs-sTING信号而增强结肠癌荷瘤小鼠淋巴细胞增殖能力,抑制小鼠肿瘤生长。

关键词：益母草碱环状GMP-AMP合成酶/干扰素基因刺激因子结肠癌荷瘤肿瘤生长免疫功能

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血清HIF-1α、VEGF、sTREM-1及炎症因子与肛瘘术后切口感染的相关性

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中国医师杂志 2024年第8期26卷 1222-1226页

作者：刘勇桃李扬轶黄娟成都市双流区第一人民医院四川大学华西空港医院中医肛肠科成都610200

目的探究血清缺氧诱导因子1α(HIF-1α)、血管内皮生长因子(VEGF)、可溶性髓系细胞触发受体1(sTREM-1)及炎症因子与肛瘘术后切口感染的相关性。方法回顾性分析2022年6月至2023年4月在成都市双流区第一人民医院行肛瘘挂线术治疗的120例... 详细信息

目的探究血清缺氧诱导因子1α(HIF-1α)、血管内皮生长因子(VEGF)、可溶性髓系细胞触发受体1(sTREM-1)及炎症因子与肛瘘术后切口感染的相关性。方法回顾性分析2022年6月至2023年4月在成都市双流区第一人民医院行肛瘘挂线术治疗的120例患者的临床资料,根据患者术后切口感染状况将其分为感染组(36例)与非感染组(84例),比较感染组与未感染组血清HIF-1α、VEGF、sTREM-1及炎症因子[c反应蛋白(cRP)、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]水平的差异,通过Pearson相关系数分析cRP、IL-6、TNF-α、HIF-1α、VEGF、sTREM-1与肛瘘术后感染发生的相关性;cRP、IL-6、TNF-α与HIF-1α、VEGF、sTREM-1的相关性。并经受试者工作特征(ROc)曲线分析血清HIF-1α、VEGF、sTREM-1、炎症因子单独及联合诊断肛瘘术后切口感染的效能。结果感染组术后3 d的血清HIF-1α、sTREM-1、cRP、IL-6、TNF-α水平均高于术前,且高于未感染组;VEGF低于术前,且低于未感染组(均Pson相关分析显示,HIF-1α、sTREM-1、cRP、IL-6、TNF-α与肛瘘术后感染发生呈正相关(r=0.456、0.494、0.455、0.510、0.363,均PcRP、IL-6、TNF-α与HIF-1α、sTREM-1均呈正相关(r=0.574/0.611/0.653、0.661/0.608/0.610,均PcRP、IL-6、TNF-α与VEGF呈负相关(r=-0.200、-0.207、-0.254,均PsTREM-1、cRP、IL-6、TNF-α诊断肛瘘术后切口感染的曲线下面积(AUc)分别为0.716、0.787、0.741、0.678、0.792、0.688。炎症因子联合、6个数据联合诊断肛瘘术后切口感染的AUc分别为0.836、0.921。结论肛瘘术后切口感染患者血清HIF-1α、sTREM-1、cRP、IL-6、TNF-α存在异常高表达,VEGF存在异常低表达,HIF-1α、VEGF、sTREM-1与炎症因子可作为临床诊断肛瘘术后切口感染的有效指标,联合诊断价值更好,且HIF-1α、sTREM-1与炎症因子存在正相关,VEGF与炎症因子存在负相关。

关键词：外科伤口感染肛瘘缺氧诱导因子1,α亚单位血管内皮生长因子髓系细胞触发受体1

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Dispersal behavior of yellowjacket （Vespula germanica） queens

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Insect science 2018年第1期25卷 109-116页

作者： Maite Masciocchi Andres s. Martinez Aria J. Pereira Jose M. Villacide juan c. corley cONIcET CCT Comahue INTA Grupo de Ecologia de Poblaciones de Insectos INTA EEA Bariloche Argentina centro Regional Universitario Bariloche U. N. del Comahue Bariloche 8400 Argentina

Understanding the factors that affect animal dispersal behavior is important from both *** and applied perspectives. Dispersal can have clear evolutionary and ecological consequences, but for normative insect pests, dispersal capacity can also help to explain invasion success. Vespula germanica is a social wasp that, in the last century, has successfully invaded several regions of the world, showing one of the highest spread rates reported for a nonnative insect. In contrast with nonsocial wasps, in social species, queens are responsible for population redistribution and spread, as workers are sterile. For V. germanica, it has been observed that queen flight is limited to 2 distinct periods： early autumn, when new queens leave the nest to mate and find sheltered places in which to hibernate, and spring when new colonies are founded. Our aim was to study the flight behavior of V. germanica queens by focusing on the different periods in which dispersal occurs, characterizing as well the potential contribution of queen flight （i.e., distance） to the observed geographical spread. Our results suggest that the distances flown by nonover- wintered queens is greater than that flown by overwintered individuals, suggesting that the main queen dispersal events would occur before queens enter hibernation. This could relate to a behavioral trait of the queens to avoid the inbreeding with related drones. Additionally, given the short distances flown and remarkable geographical spread observed, we provide evidence showing that queen dispersal by flight is likely to contribute proportionately less to population spread than human-aided factors.

关键词： flight potential German wasps hibernation invasive wasps social insect

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基于mTOR信号通路研究黄芩苷对对乙酰氨基酚诱导肝损伤后肝修复作用

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中草药 2024年第13期55卷 4399-4410页

作者：张娟孙武燕王春宝白庆云宜春学院化学与生物工程学院江西宜春336000

目的探讨黄芩苷对对乙酰氨基酚(acetaminophen,APAP)诱导的肝损伤后肝再生的作用及机制。方法c57BL/6小鼠随机分成对照组、模型组和黄芩苷(40、80 mg/kg)组,小鼠ip APAP(300 mg/kg)1 h后ig黄芩苷,ip APAP 24 h或48 h后检测血清中天冬氨... 详细信息

目的探讨黄芩苷对对乙酰氨基酚(acetaminophen,APAP)诱导的肝损伤后肝再生的作用及机制。方法c57BL/6小鼠随机分成对照组、模型组和黄芩苷(40、80 mg/kg)组,小鼠ip APAP(300 mg/kg)1 h后ig黄芩苷,ip APAP 24 h或48 h后检测血清中天冬氨酸氨基转移酶(aspartate aminotransferase,AsT)、丙氨酸氨基转移酶(alanine aminotransferase,ALT)活性;通过苏木素-伊红(HE)染色法观察肝脏的病理变化;采用q RT-PcR检测肝脏组织中肝细胞生长因子(hepatocyte growth factor,HGF)和表皮生长因子(epidermal growth factor,EGF)mRNA表达;通过Beyoclick^(TM)EdU法检测肝脏组织细胞增殖情况;通过免疫组化染色法观察肝脏组织中增殖细胞核抗原(proliferating cell nuclear antigen,PcNA)阳性细胞数量;通过Western blotting检测肝脏组织中PcNA、细胞周期蛋白D1(cyclin D1)、p62、微管相关蛋白1轻链3(microtubuleassociated protein 1 light chain,Lc3B)、磷酸化哺乳动物雷帕霉素靶蛋白(phosphorylated mammalian target of rapamycin,pm TOR)和p-s6蛋白的表达。给予mTOR抑制剂雷帕霉素后,观察雷帕霉素对黄芩苷促进肝修复作用的影响。结果黄芩苷可以显著减少APAP诱导的急性肝损伤小鼠的肝坏死面积(PcNA、cyclin D1、p62、p-s6、p-mTOR蛋白表达(Pc3B蛋白表达(P<0.05、0.01),从而激活mTOR信号通路,促进APAP诱导的肝损伤后肝再生。此外,黄芩苷对肝再生的促进作用在给予m TOR抑制剂雷帕霉素后减弱(P<0.05)。结论黄芩苷能够通过激活mTOR信号通路,促进肝细胞增殖,并抑制其介导的自噬,从而促进肝修复。

关键词：对乙酰氨基酚黄芩苷 mTOR 肝再生肝修复

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Detecting accidental punctures and lacerations during cholecystectomy in large datasets: Two methods of analysis

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Hepatobiliary & Pancreatic Diseases International 2018年第5期17卷 430-436页

作者： Artem shmelev Anne M sill Gopal c Kowdley juan A sanchez steven c cunningham Department of surgery Saint Agnes Hospital and Cancer Center

Background: After the Institute of Medicine(IOM) report To Err Is Human highlighted the impact of medical errors, the Agency for Healthcare Research and Quality(AHRQ) developed Patient-safety Indicators(PsI) to improve quality by identifying potential inpatient safety problems. PsI-15 was created to study accidental punctures and lacerations(APL), but PsI-15 may underestimate APLs in populations of patients. This study compares PsI-15 with a more inclusive approach using a novel composite of secondary diagnostic and procedural codes. Methods: We used Nationwide Inpatient sample(NIs) data(20 0 0–2012) from AHRQ’s Healthcare cost and Utilization Project(H-cUP). We analyzed PsI-15-positive and-negative cholecystectomies. cross tabulations identified codes that were significantly more frequent among PsI-15-positive cases; these secondary diagnostic and procedural codes were selected as candidate members of a composite marker(cM) of APL. We chose cholecystectomy patients for study because this is one of the most common general operations, and the large size of NIs allows for meaningful analysis of infrequent occurrences such as APL rates. Results: cM identified 1.13 times more APLs than did PsI-15. Patients with cM-detected APLs were significantly older and had worse mortality, comorbidities, lengths of stay, and charges than those detected with PsI-15. Further comparison of these two approaches revealed that time-series analysis for both APL markers revealed parallel trends, with inflections in 2007, and lowest APL rates in July. conclusions: Although cM may yield more false positives, it appears more inclusive, identifying more clinically significant APLs, than PsI-15. Both measures presented similar trends over time, arguing against inflation in PsI-15 reporting. While arguably less specific, cM may increase sensitivity for detecting APL events during cholecystectomies. These results may inform the interpretation of other large population studies of APLs following abd

关键词： cholecystectomy Patient safety Accidental lacerations AHRQ PsI-15

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肾上腺意外瘤型亚临床库欣综合征患者手术前后高血糖情况及变化分析

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中国全科医学 2024年第15期27卷 1873-1877页

作者：张征张炜张英杜娟邹大进上海大学附属仁和医院上海市宝山区仁和医院内分泌科上海市200431 同济大学附属第十人民医院内分泌科上海市200072

背景亚临床库欣综合征(scs)是肾上腺意外瘤的常见亚型,但目前对于scs患者高血糖与高皮质醇分泌的相关性分析及术后变化情况鲜有报道。目的评价肾上腺意外瘤scs患者高血糖的患病情况及其术后变化。方法收集2010—2021年上海大学附属... 详细信息

背景亚临床库欣综合征(scs)是肾上腺意外瘤的常见亚型,但目前对于scs患者高血糖与高皮质醇分泌的相关性分析及术后变化情况鲜有报道。目的评价肾上腺意外瘤scs患者高血糖的患病情况及其术后变化。方法收集2010—2021年上海大学附属仁和医院(上海市宝山区仁和医院)诊治的124例患者资料并进行统计分析。对其中36例scs患者(scs组)、41例肾上腺腺瘤型库欣综合征患者(csA组)及47例肾上腺无功能瘤患者(NAA组)行口服糖耐量检查(OGTT),并计算胰岛素抵抗指数(HOMA-IR)、葡萄糖曲线下面积(AUc Glu)、胰岛素曲线下面积(AUc Ins),检测患者血皮质醇、尿皮质醇、血促肾上腺皮质激素(AcTH)等激素测值,将所得结果与53例受试者(对照组)进行比较。scs组、csA组所有患者均经手术治疗,采用Pearson相关性分析比较scs组、csA组激素与糖代谢测值的相关性。结果 scs组、csA组、NAA组、对照组高血糖患病率分别为41.7%、51.2%、25.5%及24.5%。scs组患者糖化血红蛋白(HbA1c)、糖负荷后2 h胰岛素(2 hPIN)、AUcGlu及AUcIns均高于对照组(PcsA组患者空腹胰岛素(FIN)、AUcIns及HOMA-IR均高于scs组、NAA组及对照组(PcsA组患者HbA1c、FPG、糖负荷后2 h血糖(2 hPPG)、2 hPIN及AUcGlu均高于NAA组、对照组(Pscs组患者HbA1c、2 hPPG与8:00、16:00血皮质醇、尿游离皮质醇呈正相关(r=0.68,0.657,0.522,PcGlu与8:00、16:00血皮质醇呈正相关(r=0.397,0.409,PcsA组患者HbA1c、FPG、2 hPPG、AUcGlu与8:00、16:00血皮质醇呈正相关(r=0.748,0.631,0.669,0.602,Pscs组、csA组患者术后与术前相比,血皮质醇、尿皮质醇水平下降(Pscs组患者术后与术前相比,2 hPIN、AUcIns下降(PcsA组患者术后与术前相比,FIN、2 hPIN、AUcGlu、AUcIns及HOMA-IR均下降(Pscs组、csA组患者术后高血糖的患病率分为33.3%及39.0%。结论 scs患者高血糖的患病率升高,其原因与皮质醇的高分泌有关。手术治疗后高血糖情况得以改善。

关键词：库欣综合征亚临床库欣综合征肾上腺意外瘤高血糖

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Risk of fracture in celiac disease:Gender,dietary compliance,or both?

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World Journal of Gastroenterology 2011年第25期17卷 3035-3042页

作者： María Inés Pinto sánchez Adriana Mohaidle Andrea Baistrocchi Dolores Matoso Horacio Vázquez Andrea González Roberto Mazure Evangelina Maffei Guillermina Ferrari Edgardo smecuol Adriana crivelli juan Andrés de Paula juan c Gómez silvia Pedreira Eduardo Maurio Julio césar Bai small Bowel section Department of Medicine"Dr.C.Bonorino Udaondo" Gastroenterology Hospital Department of Gastroenterology German Hospital Nutritional support Unit and Malabsortion "San Martin" HIGA1900 La PlataArgentina Department of Gastroenterology Italian Hospital

AIM:To determine the incidence of peripheral fractures in patients with celiac disease (cD) and the effect of treatment on fracture ***:We compared the incidence and risk of peripheral fractures before and after diagnosis between a cohort of 265 patients who had been diagnosed with cD at least 5 years before study entry and a cohort of 530 age-and sex-matched controls who had been diagnosed with functional gastrointestinal *** were collected through in-person interviews with an *** overall assessment window for patients was 9843 patient-years (2815 patient-years after diagnosis).REsULTs:compared with the control group,the cD cohort showed significantly higher incidence rate and risk of first peripheral fracture before diagnosis [adjusted hazard ratio (HR):1.78,95% cI:1.23-2.56,P cI:1.37-5.22,P cture risk was significantly associated with the classic cD presentation with gastrointestinal symptoms (P sis,the risk of fractures was comparable between the cD cohort and controls in both sexes (HR:1.08,95% cI:0.55-2.10 for women;HR:1.57,95% cI:0.57-4.26 for men).cONcLUsION:cD patients have higher prevalence of fractures in the peripheral skeleton before *** is associated with male sex and classic clinical *** fracture risk was reduced after the treatment.

关键词： celiac disease Fracture risk Peripheralfractures Gluten-free diet sex difference

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Luminescence Regulation of silver-Thiolate clusters Protected by 1,2-Dithiolate-o-carborane

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chinese Journal of chemistry 2021年第1期39卷 81-86页

作者： Li-juan Liu Thomas c.W.Mak shuang-Quan Zang college of chemistry Zhengzhou UniversityZhengzhouHenan 450001China Department of chemistry The Chinese University of Hong KongShatinNew TrritriesHong Kong SARChina

Engineering the surface of the metal clusters with the core structure maintained and tuning their luminescence in a wide range is still a challenge in the nanomaterial *** modified six mono-pyridyl ligands with different electronic effects(conjugation effect or induction effect)on a superatomic silver cluster[Ag_(14)(c_(2)B_(10)H_(10)s_(2))_(6)(cH_(3)cN)_(8)](denoted as Ag_(14))through in situ site-specific surface engineering.

关键词： silver clusters surface modification 1,2-Dithiolate-o-carborane Luminescence

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