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URBAN PHOTOVOLTAIC POTENTIAL OF INCLINED ROOFING FOR BUILDINGS IN HERITAGE CENTERS IN EQUATORIAL AREAS

Journal of Green Building 2018年第3期13卷 45-69页

作者： Esteban Zalamea-León juan Mena-Campos antonio Barragán-Escandón Diego Parra-González Pablo Méndez-Santos Facultad de Arquitectura y Urbanismo Universidad de Cuenca(School of Architecture and UrbanismUniversity of Cuenca) Departamento de Ingeniería Gráfica Diseño and ProyectosUniversidad de Jaén(Department of Graphic EngineeringDesign and ProjectsUniversity of Jaén)JaénSpain.Department of Electrical EngineeringUniversidad Politécnica SalesianaCuencaEcuador Facultad de Ingeniería Universidad de Cuenca(Faculty of EngineeringUniversity of Cuenca) Departamento de Ingeniería Eléctrica Universidad Politécnica Salesiana(Department of Electrical EngineeringSalesiana Polytechnic University)

In situ renewable energy production is a favourable alternative for reducing pollu-tion and combating climate *** research area,Cuenca,Ecuador,is located in the Andes near the equator with optimal conditions for energy self-supply due to its low energy demands and low levels of irradiation *** this study,tem-porary fluctuations in consumption based on 2016 electricity consumption data are *** GIS,available roofing polygons are obtained,and the amount of usable solar radiation is estimated based on these *** available surface,orientation,and inclination information,electricity generation based on photovoltaic performance is estimated and compared for monocrystalline silica panels and pho-tovoltaic solar roof tiles,which are architectural alternatives.A potential net supply of 148%is found for monocrystalline silica photovoltaic panels in a typical format,whereas that of photovoltaic tiles is only 61%.In addition,production-demand imbalances are predicted in extreme months and average months and on extreme days due to variations in irradiation and demands.

关键词： solar energy photovoltaic on buildings photovoltaic architectural integration heritage centres energy efficiency

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Colorectal peritoneal metastases:Optimal management review

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World Journal of Gastroenterology 2019年第27期25卷 3484-3502页

作者： juan Manuel Sánchez-Hidalgo Lidia Rodríguez-Ortiz Alvaro Arjona-Sánchez Sebastián Rufián-Pena Angela Casado-Adam antonio Cosano-Alvarez Javier Briceno-Delgado Department of General and Digestive Surgery Reina Sofia University HospitalCordoba 14004Spain

The peritoneum is a common site of dissemination for colorrectal cancer, with a poorer prognosis than other sites of metastases. In the last two decades, it has been considered as a locoregional disease progression and treated as such with curative intention treatments. Cytoreductive surgery(CRS) and hyperthermic intraperitoneal chemotherapy(HIPEC) is the actual reference treatment for these patients as better survival results have been reached as compared to systemic chemotherapy alone, but its therapeutic efficacy is still under debate. Actual guidelines recommend that the management of colorectal cancer with peritoneal metastases should be led by a multidisciplinary team carried out in experienced centers and consider CRS + HIPEC for selected patients. Accumulative evidence in the last three years suggests that this is a curative treatment that may improve patients disease-free survival, decrease the risk of recurrence, and does not increase the risk of treatment-related mortality. In this review we aim to gather the latest results from referral centers and opinions from experts about the effectiveness and feasibility of CRS + HIPEC for treating peritoneal disease from colorectal malignancies.

关键词： Peritoneal metastases Colorectal cancer Cytoreductive surgery Hyperthermic intraperitoneal chemotherapy Peritoneal carcinomatosis

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Surgical Excision of Ischiorectal Fossa Tumors

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Surgical Science 2016年第10期7卷 461-465页

作者： Javier Die Trill juan Carlos García Irene Moreno juan Diego Pina Estela Tobaruela Jose Barquin juan Ocaña antonio Rey Department of Surgery Hospital Ramón y Cajal Madrid Spain

Background: Ischiorectal Fossa Tumors are rare and their management has not been protocolized. Patients: We retrospectively review four consecutive cases treated in our department, from January 2015 to July 2015. All of them were discussed in a multidisciplinary team meeting. None of them were secondary to an inflammatory process. Results: A Magnetic Resonance Imaging was performed in all the four patients, and as it was not a malignant diagnosis made in any of them, we proceeded to resecate the lesions. None biopsies were performed and the benign diagnoses were confirmed by the pathologist. All the patients underwent a local posterior or perineal approach, because all the lesions (epidermoid cyst, hamartoma, lipoma and an aggressive angiomyxoma) were localized purely in the ischiorectal fossa, under the levator ani muscle and not invading any adjacent structures. In all of them, an R0 resection was performed. Conclusions: Ischiorectal fossa tumors are rare and there are few cases already published. Non-inflammatory lesions located in the ischiorectal fossa, with none invasion of rectum or levator ani muscle, are mainly benign lesions prone to their complete excision by a posterior approach. Biopsy is not always necessary unless there’s a suspicion of a malignancy or invasion of adjacent structures, and only in that case a biopsy should be made, because in some of them, a neo-adjuvant treatment can be useful to reduce the tumor and to perform an R0 resection.

关键词： Ischiorectal Fossa Tumors Aggressive Angiomyxoma

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Temperature Field on Structural Carbon Steel under Fire Conditions

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材料科学与工程（中英文B版） 2011年第6期1卷 725-735页

作者： juan antonio Trilleros Villaverde Sonia Mato Diaz Irene Huertas Gonzalez Department of Materials Science and Metallurgical Engineering Universitas Complutensis of Madrid Ciudad Universitaria s/nMadrid 28040 Spain

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Corneal collagen cross‑linking epithelium‑on ***‑off:a systematic review and meta‑analysis

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Eye and Vision 2021年第6期8卷 338-352页

作者： Francesco D’Oria antonio Palazón Jorge L.Alio Vissum Innovation c/Cabañal103016 AlicanteSpain Division of Ophthalmology Universidad Miguel HernándezAlicanteSpain Section of Ophthalmology Department of Basic Medical ScienceNeuroscience and Sense OrgansUniversity of BariBariItaly Department of Clinical Medicine Miguel Hernández UniversitySan Juan de AlicanteSpain

Background:The purpose of the study was to determine the advantages and disadvantages of epi-on corneal crosslinking(CXL)techniques compared with standard epi-off ***:We searched MEDLINE and EMBASE for randomized controlled trials(RCTs)and non-randomized studies of interventions(NRSIs)and we evaluated the selected papers according to the Cochrane risk of bias *** considered,as primary outcomes,average Kmax flattening,changes in uncorrected and corrected distance visual acuity(UDVA and CDVA);as secondary outcomes,we considered changes in pachymetry values and endothelial cell density(ECD).We also investigated adverse events related to the treatments and treatment ***-analysis was conducted with a fixed or random-effects model using weighted mean difference(MD)with 95%confidence interval(CI)as the effect ***:A total of 15 studies were included and among these 15 trials,9 were RCTs and 6 were NRSIs,but only 4 studies showed no high risk of bias and were included in this *** analysis revealed significant postoperative differences in CDVA(MD=0.07;95%CI 0.04 to 0.10;P0.05).Epi-on CXL protocol was found to be significantly less prompt to have risks of delay in epithelial healing(P=0.035)and persistent stromal haze(P=0.026).Conclusion:Epi-on CXL is as effective as epi-off *** for a higher significant improvement in CDVA with current epi-on protocols,our meta-analysis demonstrates that epi-on and epi-off CXL have comparable effects on visual,topographic,pachymetric,and endothelial ***-on CXL has clinical advantages in terms of comfort and avoidance of complications as it reduces the risk of developing delay in epithelial healing and persistent stromal haze.

关键词： Corneal collagen cross-linking Keratoconus Transepithelial CXL Epithelium-off CXL Epithelium-on CXL Iontophoresis

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High prevalence of hepatic steatosis and vascular thrombosis in COVID-19:A systematic review and meta-analysis of autopsy data

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World Journal of Gastroenterology 2020年第48期26卷 7693-7706页

作者： Luis antonio Díaz Francisco Idalsoaga Macarena Cannistra Roberto Candia Daniel Cabrera Francisco Barrera Alejandro Soza Rondell Graham Arnoldo Riquelme Marco Arrese Michael D Leise juan Pablo Arab Department of Gastroenterology Escuela de MedicinaPontificia Universidad Católica de ChileSantiago 8320000Chile Department of Internal Medicine Pontificia Universidad Católica de ChileSantiago 8320000Chile School of Medicine Pontificia Universidad Católica de ChileSantiago 8320000Chile Facultad de Ciencias Médicas Universidad Bernardo O'HigginsSantiago 8320000Chile Department of Laboratory Medicine and Pathology Mayo Clinic RochesterMinnesotaMN 55902United States Católica de Chile Santiago 8320000Chile Division of Gastroenterology and Hepatology Mayo Clinic RochesterMinnesotaMN 55905United States

BACKGROUND Coronavirus disease 2019(COVID-19)disease can frequently affect the *** on hepatic histopathological findings in COVID-19 is *** To characterize hepatic pathological findings in patients with *** We conducted a systematic review with meta-analysis registered on PROSPERO(CRD42020192813),following PRISMA *** trials were those including patients of any age and COVID-19 diagnosis based on a molecular *** reports from deceased COVID-19 patients undergoing autopsy or liver biopsy were *** including less than ten patients were *** were pooled using random-effects models.Q statistic and I2 were used to assess heterogeneity and levels of evidence,*** We identified 18 studies from 7 countries;all were case reports and case series from *** the patients were over 15 years old,and 67.2%were *** performed a meta-analysis of 5 studies,including 116 *** prevalence estimates of liver histopathological findings were hepatic steatosis 55.1%[95%confidence interval(CI):46.2-63.8],congestion of hepatic sinuses 34.7%(95%CI:7.9-68.4),vascular thrombosis 29.4%(95%CI:0.4-87.2),fibrosis 20.5%(95%CI:0.6-57.9),Kupffer cell hyperplasia 13.5%(95%CI:0.6-54.3),portal inflammation 13.2%(95%CI:0.1-48.8),and lobular inflammation 11.6%(95%CI:0.3-35.7).We also identified the presence of venous outflow obstruction,phlebosclerosis of the portal vein,herniated portal vein,periportal abnormal vessels,hemophagocytosis,and *** We found a high prevalence of hepatic steatosis and vascular thrombosis as major histological liver *** frequent findings included portal and lobular inflammation and Kupffer cell hyperplasia or *** studies are needed to establish the mechanisms and implications of these findings.

关键词： Pathology SARS-CoV-2 COVID-19 Autopsies Liver Liver biopsies

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Numerous unreported glacial lake outburst floods in the Third Pole revealed by high-resolution satellite data and geomorphological evidence

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Science Bulletin 2021年第13期66卷 1270-1273,M0003页

作者： Guoxiong Zheng Anming Bao Simon Allen juan antonio Ballesteros-Cánovas Ye Yuan Guli Jiapaer Markus Stoffel State Key Laboratory of Desert and Oasis Ecology Xinjiang Institute of Ecology and GeographyChinese Academy of SciencesUrumqi 830011China Climatic Change Impacts and Risks in the Anthropocene Institute for Environmental SciencesUniversity of GenevaGeneva 1205Switzerland University of Chinese Academy of Sciences Beijing 100049China Department of Geography University of ZurichZurich 8057Switzerland Dendrolab.ch Department of Earth SciencesUniversity of GenevaGeneva 1205Switzerland Department of F.A.Forel for Environmental and Aquatic Sciences University of GenevaGeneva 1205Switzerland

The“Third Pole”usually refers to the Tibetan Plateau and surroundings as it is the largest glaciated zone on Earth after the Antarctic and Arctic[1].It is also one of the major hotspots in the world suffering from w... 详细信息

关键词：念青唐古拉山第三极高分辨率卫星影像热点地区 F事件无人区天山地区

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Number of Calving and Its Relationship with Productive Indicators in Nelore Cows

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Journal of Agricultural Science and Technology(A) 2020年第3期10卷 151-158页

作者： Atsuko Ikeda Fernando Guzman Vaca juan antonio Pereira Pablo Roberto Marini Faculty of Veterinary Sciences National University of RosarioS2170HGArgentina Faculty of Veterinary and Zootectist Autonomy University of GarielRene MorenoAve.26 de FebreroSanta CruzBolivia

The objective of this study was to evaluate the relationship of the calving number with productive indicators in Nelore cows in a grazing system in the Bolivian *** data,corresponding to the period between 1991 and 2019 referred to 1,566 primiparous and multiparous Nelore breed cows were used.A decrease in the total number of animals was observed from the first to the fifth calving,it was also observed that the age of the first calving was similar in all cows without significant differences,showing that longevity is not associated with the age at the first *** weight presented significant differences(p≤0.05),according to the number of calvings;the fourth and fifth calving cows are the *** of calf at birth did not show a relationship with the number of calvings ***,it does so in the weight of calf at weaning,which increases from the first to the fifth calving with significant differences(p≤0.05).There were significant differences(p≤0.05)for the interval between calvings,decreasing as the calvings *** is concluded that there is a relationship between the number of calving with productive indicators in Nelore cows in a grazing system in the Bolivian tropics,fundamentally those efficiency variables where longevity is important.

关键词： Zootechnic efficiency interval between calvings calf weight at weaning accumulative production grazing system

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Myelin lipid deficiency:a new key driver of Alzheimer’s disease

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Neural Regeneration Research 2023年第1期18卷 121-122页

作者： Shulan Qiu juan Pablo Palavicini Xianlin Han Barshop Institute for Longevity and Aging Studies Division of DiabetesDepartment of MedicineUniversity of Texas Health Science Center at San AntonioSan AntonioTXUSA

Lipids play essential biological functions that include acting as components of biological membranes,energy storage,signaling,nutrients,transporters,enzyme activators,among *** with the multiple research methods to assess DNA,RNA,and protein content,location,and function in cells,there are relatively fewer methods to study ***,lipid-oriented mechanistic studies remain rare and challenging.

关键词： Alzheimer rare challenging

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Natural and Semi-Synthetic Pseudoguaianolides as Inhibitors of NF-κB

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Journal of Biomedical Science and Engineering 2014年第10期7卷 833-847页

作者： Rodrigo Villagomez juan antonio Collado Eduardo Munoz Giovanna Almanza Olov Sterner Center for Analysis and Synthesis Lund UniversityLundSweden Laboratorio de Bioorganica Instituto de Investigaciones QuímicasUniversidad Mayor de San AndrésLa PazBolivia Instituto Maimónides de Investigación Biomédica de Córdoba(IMIBIC) Departamento de Biología CelularFisiología e InmunologíaUniversidad de CórdobaCórdobaSpain

Damsin (1) is a natural pseudoguaianolide sesquiterpene that inhibits NF-κB, a protein complex that controls the transcription of DNA in mammalian cells, and has a potential for standing model for the development of new anti-cancer lead structures. In order to do a preliminary structure-activity study and improve the anti-cancer activity, fourteen derivatives and analogs were prepared and evaluated. These were chosen to represent both structural diversity and structural novelty. The importance of α methylene-γ-lactone moiety for the anti-cancer activity was confirmed, even though other features in the scaffold were shown to be important for the activity. In some cases a new substitution negatively affected the initial activity, however, two analogues, indolo [3,2-c]-4-desoxydamsin (5) and ambrosin (6), were found to be more potent.

关键词： Damsin α Methylene-γ-Lactone Sesquiterpenoids Anti-Cancer Activity

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