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Pleistocene history of Iberomys,an endangered endemic rodent from southwestern Europe

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Integrative Zoology 2014年第4期9卷 481-497页

作者： Gloria CUENCA-BESCÓS juan Manuel LÓPEZ-GARCÍA María Angeles GALINDO-PELLICENA Rosa GARCÍA-PEREA Julio GISBERT juan ROFES Jacint VENTURA Research Group Aragosaurus-IUCA PaleontologyEarth Sciences DepartmentUniversity of ZaragozaZaragozaSpain Research Group of Paleobiology and Prehistory Human Studies DepartmentUniversity of FerraraFerraraItaly Research Institute of Evolution and Human Behavior UCM-ISCIIIMadridSpain GALEMIA Conservation and Study of Forgotten VertebratesMadridSpain Department of Stratigraphy and Paleontology Faculty of Sciences and TechnologyUniversity of the Basque CountryGipuzkoaGuipúzcoaSpain Department of Animal Biology Plant Biology and EcologyFaculty of BiosciencesUniversity Autonoma de BarcelonaBarcelonaSpain

The extant cabrera’s vole,Microtus cabrerae,differs in morphology and evolutionary history from the other species of *** arvicoline has unique derived features in the cranium,mandible and ***bly its most conspicuous features are its large size,the high skull in lateral view,the long and distally broad nasals,and the triangle shape of the anteroconid complex,with a marked labio-lingual asymmetry of the occlusal surface of the first lower *** this study,we propose a phylogenetic lineage that includes cabrera’s vole in what until now has been the Microtus subgenus *** information and several life history traits support the elevation of Iberomys to the rank of *** Iberomys comprises species that have appeared in succession during the Quaternary:in the Early Pleistocene,the extinct *** in the Middle Pleistocene,the extinct *** and in the Late Pleistocene,the extant ***,the extant species shows several biological singularities,such as multiple polymorphic copies of the SRY male-specific gene in both males and females,and the lowest basal metabolic rate in relation to weight among arvicoline ***,its habitat requirement is unique among the Iberian ***,the biological and paleontological data that we present in this work support the elevation of its taxonomic rank to that of ge*** study also suggests a modification of nomenclature:Microtus(Iberomys)brecciensis is replaced with *** and the common name of the extant M.(I.)cabrerae changed from‘topillo’to‘iberon’to improve conservation and protection actions.

关键词： cabrera’s vole conservation Iberoccitanian endemism Iberomys origin

Parameters Influencing the Optimization Process in Airborne Particles PM10 Using a Neuro-Fuzzy Algorithm Optimized with Bacteria Foraging (BFOA)

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International Journal of Intelligence Science 2019年第3期9卷 67-91页

作者： Maria del Carmen cabrera-Hernandez Marco Antonio Aceves-Fernandez juan Manuel Ramos-Arreguin Jose Emilio Vargas-Soto Efren Gorrostieta-Hurtado Faculty of Engineering Universidad Autónoma de Querétaro Cerro de las Campanas S/N Querétaro Mexico

The airborne pollutants monitoring is an overriding task for humanity given that poor quality of air is a matter of public health, causing issues mainly in the respiratory and cardiovascular systems, specifically the PM10 particle. In this contribution is generated a base model with an Adaptive Neuro Fuzzy Inference System (ANFIS) which is later optimized, using a swarm intelligence technique, named Bacteria Foraging Optimization Algorithm (BFOA). Several experiments were carried with BFOA parameters, tuning them to achieve the best configuration of said parameters that produce an optimized model, demonstrating that way, how the optimization process is influenced by choice of the parameters.

关键词： Air Pollution Bacterial Foraging Optimization Algorithm (BFOA) Swarm Intelligence ANFIS

Population Dynamics of Colonizing Fauna and Its Effect on Growth Rates of the Farmed Red Alga Alsidium triquetrum (S. G. Gmelin) Trevisan

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Natural Science 2022年第2期14卷 42-55页

作者： Ruben cabrera Arsenio J. Areces Jhoana Díaz-Larrea Sunil Kumar Sahu juan Ricardo Cruz-Aviña Laura G. Nuñez García Gabinete de Arqueología Oficina del Historiador de la Ciudad Habana Vieja Cuba Instituto de Geografía Tropical Ministerio de Ciencia Tecnología y Medio Ambiente Municipio Playa Ciudad Habana Cuba Departamento de Hidrobiología Universidad Autónoma Metropolitana Unidad Iztapalapa CBS Cd de México México State Key Laboratory of Biocontrol Guangdong Key Laboratory of Plant Resources School of Life Science Sun Yat-Sen University Guangzhou China Facultad de Medicina Veterinaria y Zootecnia BUAP Laboratorio de Medicina de la Conservación Licenciatura en Medicina Veterinaria y Fauna Silvestre Km. 7.5 Carretera Ca&ntilde ada Morelos El Salado Tecamachalco Puebla Mexico

Herbivores can drastically alter the morphology of macroalgae by directly consuming tissue and by inflicting structural wounds. Macroalgae host abundant and diverse epibiont communities, the dynamics of which tend to be mostly unknown in space and time. As the cultivation of macroalgae gains momentum worldwide, it is key to measure how epibionts could affect algal performance. We examined the epibiont community associated with farmed Alsidium triquetrum, a red macroalga with growing pharmacological interest. Measurements were conducted over two independent 60-day periods, one in summer and one in winter. Epibionts showed different patterns of succession in both seasons. Crustaceans, mainly amphipods, showed the highest overall density, with deleterious effects on daily growth rates of A. triquetrum in winter. Adverse effects as a function of epibionts were not detected in summer. A. triquetrum is a perennial alga. However, its performance as a crop in the nearshore can be significantly affected by the epibiont community structure that persists in winter. Amphipods and ascoglossan molluscs were risk factors in the mariculture of this agarophyte. In winter, they can destroy plants when they reach more than five individuals per gram of fresh biomass. Results highlight that commercial farming of A. triquetrum would be successful if grown throughout the summer.

关键词： Cultivation Epifauna Macroalgae Macroinvertebrates Seaweed Mariculture

Reconstruction of lateral root formation through single-cell RNA sequencing reveals order of tissue in itiation

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Molecular Plant 2021年第8期14卷 1362-1378页

作者： Laura Serrano-Ron Pablo Perez-Garcia Alvaro Sanchez-Corrionero Inmaculada Gude Javier cabrera Pui-Leng Ip Kenneth D.Birnbaum Miguel A.Moreno-Risueno Centro de Biotecnologia y Genomica de Plantas Universidad Politecnica de Madrid(UPM)-lnstituto Naci on al de Investigacion y Tec no logia Agraria y Alimentaria(INIA)Pozuelo de Alarcon28223 MadridSpain Departamento de Biotecnologia-Biologia Vegetal Escuela Tecnica Superior de Ingenieria AgronomicaAlimentaria y de BiosistemasUniversidad Politecnica de Madrid(UPM)28040 MadridSpain Center for Genomics and Systems Biology Department of BiologyNew York UniversityNew YorkNYUSA

Postembryonic organogenesis is critical for plant ***,lateral roots(LRs)form the bulk of mature root systems,yet the ontogeny of the LR primordium(LRP)is not *** this study,we performed the single-cell RNA sequencing through the first four stages of LR formation in *** analysis led to a model in which a single group of precursor cells,with a cell identity different from their pericycle origins,rapidly reprograms and splits into a mixed ground tissue/stem cell niche fate and a vascular precursor *** ground tissue and stem cell niche fates soon separate and a subset of more specialized vascular cells form sucrose transporting phloem cells that appear to connect to the primary *** did not detect cells resembling epidermis or root cap,suggesting that outer tissues may form later,preceding LR *** this stage,some remaining initial precursor cells form the primordium flanks,while the rest create a reservoir of pluripotent cells that are able to replace the LR if *** ablation of the central and lateral LRP regions showed that remaining cells restart the sequence of tissue initiation to form a ***,our study reveals an ontological hierarchy for LR formation with an early and sequential split of main root tissues and stem cells.

关键词： organogenesis patterning stem cells single-cell RNA-seq cell fate regeneration

Effect of Chitosaccharides in Nodulation and Growth in Vitro of Inoculated Soybean

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American Journal of Plant Sciences 2016年第9期7卷 1380-1391页

作者： Daimy Costales Alejandro Bernardo Falcón María Caridad Nápoles Julien de Winter Pascal Gerbaux Robertus Cornelis Adrianus Onderwater Ruddy Wattiez juan Carlos cabrera Grupo de Productos Bioactivos Departamento de Fisiología y Bioquímica Vegetal Instituto Nacional de Ciencias Agrícolas (INCA) San José de las Lajas Cuba Interdisciplinary Center for Mass Spectrometry Organic Synthesis and Mass Spectrometry Laboratory University of Mons Unité Biotechnologie Ghislenghiem Belgium Unité Biotechnologie Materia Nova ASBL Ghislenghien Belgium Biosciences Research Institute Department of Proteomics and Microbiology University of Mons—UMONS Mons Belgium

The influence of chitosaccharides on the symbiotic interaction between Bradyrhizobium and soybean was examined. The results show that chitosaccharides either positively or negatively affect soybean nodulation or plant growth depending on their molecular weight, concentration and the application methods. When directly added to the in vitro culture media, chitosan of high molecular weight inhibit Bradyrhizobium viability in a dose dependent manner while chitooligosaccharides reduce slightly the bacteria viability only at concentration equal or higher than 50 mg·L-1. Chitooligosaccharides significantly enhance nodule formation and dry mass in soybean roots at doses between 10 and 100 mg·L-1. Both types of chitosaccharides, at the highest doses (>500 mg·L-1), negatively affect plant height and root size, whereas medium doses (50 to 100 mg·L-1) increase slightly leave number. Under field conditions, foliar application of both chitosaccharides enhances growth and nodulation of soybean plants. Nevertheless, using this application method, chitosan remains more effective than chitooligosaccharides.

关键词： Chitosan Glycine max Bradyrhizobium Antimicrobial

Recombinant streptokinase vs phenylephrine-based suppositories in acute hemorrhoids, randomized, controlled trial(THERESA-3)

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World Journal of Gastroenterology 2014年第6期20卷 1594-1601页

作者： Francisco Hernández-Bernal Georgina Castellanos-Sierra Carmen M Valenzuela-Silva Karem M Catasús-lvarez Roselin Valle-cabrera Ana Aguilera-Barreto Pedro A López-Saura Center for Genetic Engineering and Biotechnology "juan B. Zayas" Hospital National Center for the Coordination of Clinical Trials

AIM: To compare the efficacy and safety of recombinant streptokinase (rSK) and phenylephrine-based suppositories in acute hemorrhoidal disease.

关键词： Streptokinase Suppository Phenylephrine Thrombolysis Hemorrhoids Randomized clinical trial

The Iberian Roma Population Variant Server(IRPVS)

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Journal of Genetics and Genomics 2024年第7期51卷 769-773页

作者： Fabiola Mavillard Javier Perez-Florido Francisco M.Ortuño Amador Valladares Miren L.Álvarez-Villegas Gema Roldán Rosario Carmona Manuel Soriano Santiago Susarte Pilar Fuentes Daniel López-López Ana María Nuñez-Negrillo Alejandra Carvajal Yolanda Morgado Daniel Arteaga Rosa Ufano Pablo Mir juan F.Gamella Joaquín Dopazo Carmen Paradas Macarena.cabrera-Serrano Instituto de Biomedicina de Sevilla(IBiS) Hospital Universitario Virgen del Rocío/CSIC/Universidad de SevillaSevillaSpain Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas(CIBERNED) Instituto de Salud CarlosⅢSevillaSpain Plataforma Andaluza de Medicina Computacional Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevillaSpain Grupo de medicina computacional de sistemas Instituto de Biomedicina de Sevilla(IBiS)Hospital Virgen del RocíoSevillaSpain Nodo de Genómica Funcional (INB-ELIXIR-es)Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevilla 41013Spain Bioinformática en Enfermedades raras(BiER) Centro de Investigación Biomédica en Red de Enfermedades Raras(CIBERER)Instituto de salud CarlosⅢSevillaSpain Departamento de Ingeniería de Computadores Automática y RobóticaUniversidad de GranadaGranadaSpain Servicio de Urgencias de Atención Primaria Distrito SevillaSevillaSpain Centro de Servicios Sociales Negociado de Servicios EspecializadosAyuntamiento de SevillaSevillaSpain Departamento de Enfermería Facultad de Ciencias de la SaludUniversidad de GranadaGranadaSpain Departamento de Neurología Hospital Virgen de las NievesGranadaSpain Departamento de Neurología Hospital Virgen de ValmeSevillaSpain Centro de Salud Utrera Sur SevillaSpain Centro de Salud Polígono Sur SevillaSpain Unidad de Trastornos del Movimiento Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain Departamento de Medicina Facultad de MedicinaUniversidad de SevillaSevilleSpain Departamento de Antropología Social Universidad de GranadaSpain Unidad Enfermedades Neuromusculares Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain

In recent years,the number of known disease genes has exponentially grown due to the widespread adoption of cost-effective massive parallel *** identify new disease variants,especially in monogenic disorders,a frequen... 详细信息

关键词： Server filtering massive

Response of rice cultivation to biofertilizers in Campeche, Mexico

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Agricultural Sciences 2013年第12期4卷 715-720页

作者： Fermín Orona-Castro Mónica Guadalupe Lozano-Contreras Martín Tucuch-Cauich Oscar A. Grageda.cabrera juan Medina-Mendez Arturo Díaz-Franco Esaú Ruiz-Sánchez Jesús Soto-Rocha Campo Experimental Bajío (INIFAP) Celaya México Campo Experimental Río Bravo (INIFAP) Rio Bravo México Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias (INIFAP) Campo Experimental Edzna Campeche México Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias (INIFAP) Campo Experimental Mococha Yucatán México Instituto Tecnológico de Conkal Conkal México

The activity of various biofertilizers on rice production (Sabanero A95) was evaluated in Palizada, Campeche, Mexico, in the wet season of 2009 (year one) and 2011 (year two). On year one, arbuscular mycorrhiza INIFAP? (Rhizophagus intraradices), Azospirillum brasilense plus arbuscular micorrhiza Rhizophagus sp., and chemical fertilizer (92, -92, -60 kg·ha-1) were evaluated, while on year two marine algae extracts, a consortium of growth promoting bacteria (Pseudomonas spp.) and a control (not fertilized) were evaluated. The results showed that there were no significant differences on grain yield among treatments during the year one. The average grain yield was 2,800 kg·ha-1. As for the year two, the highest grain yield was observed on plots fertilized with chemical fertilizer (3333 kg·ha-1), followed by plots treated with mycorrhiza INIFAP? (3000 kg·ha-1). The economic analysis for rice production in both years showed that the use of arbuscular mycorrhiza decreases the cost of production by 18.5% and 16.3%, which suggests that microbial inoculants might be good substitutes of chemical fertilizers in rice production.

关键词： Rice Wet Season Validation Biofertilizers

Prognostic performance of an index based on lactic dehydrogenase and transaminases for patients with liver steatosis and COVID-19

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World Journal of Gastroenterology 2022年第37期28卷 5444-5456页

作者： Ricardo Ulises Macías-Rodríguez Alberto Adrián Solís-Ortega Victoria J Ornelas-Arroyo Astrid Ruiz-Margáin Maria Sarai González-Huezo Nestor A Urdiales-Morán Berenice M Román-Calleja juan M Mayorquín-Aguilar JoséA González-Regueiro Alejandro Campos-Murguía Israel Vicente Toledo-Coronado Mónica Chapa-Ibargüengoitia Bernardo Valencia-Peña Carlos Fernando Martínez-cabrera Nayelli C Flores-García Department of Gastroenterology Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico City 14080Mexico Department of Gastroenterology Centro Médico ISSEMYMToluca 52140Mexico Department of Radiology Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico City 14080Mexico

BACKGROUND Metabolic associated fatty liver disease(MAFLD)is associated with complications and mortality in patients with coronavirus disease 2019(COVID-19).However,there are no prognostic scores aimed to evaluate the risk of severe disease specifically in patients with MAFLD,despite its high *** dehydrogenase,aspartate aminotransferase and alanine aminotransferase have been used as markers of liver ***,we propose an index based on lactate dehydrogenase,aspartate aminotransferase and alanine aminotransferase for the prediction of complications and mortality in patients with MAFLD and *** To evaluate the prognostic performance of an index based on lactate dehydrogenase and transaminases(aspartate aminotransferase/alanine aminotransferase)in patients with COVID-19 and MAFLD[liver fibrosis and nutrition(LNF)-COVID-19 index].METHODS In this retrospective cohort study,two cohorts from two different tertiary centers were *** first was the derivation cohort to obtain the score cutoffs,and the second was the validation *** included hospitalized patients with severe COVID-19 and *** steatosis was evaluated by computed tomography *** under the receiver operating characteristic(ROC)curve analysis and survival analysis were *** In the derivation cohort,44.6%had MAFLD;ROC curve analysis yielded a LFN-COVID-19 index>1.67 as the best cutoff,with a sensitivity of 78%,specificity of 63%,negative predictive value of 91%and an area under the ROC curve of *** the multivariate analysis,the LFN-COVID-19 index>1.67 was independently associated with the development of acute kidney injury(odds ratio:1.8,95%confidence interval:1.3-2.5,P<0.001),orotracheal intubation(odds ratio:1.9,95%confidence interval:1.4-2.4,P<0.001),and death(odds ratio:2.86,95%confidence interval:1.6-4.5,P<0.001)in both *** LFN-COVID-19 index has a good performance to predict prognosis in patients with MAFLD and COVID-19,which

关键词： COVID-19 Metabolic associated fatty liver disease Lactate dehydrogenase Transaminases Prognosis Nonalcoholic fatty liver disease