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Trend of glaucoma internal filtration surgeries in a tertiary hospital in China

International Journal of Ophthalmology(English edition) 2023年第2期16卷 251-259页

作者： Yang Cao Hai-Shuang Lin Hui-Yan Mao Yin Zhao Yan-Qian Xie Shao-Dan Zhang Qi Zhang pei-juan Wang Guo-Xing Li Ai-Wu Fang Yuan-Bo Liang The Eye Hospital School of Ophthalmology and OptometryWenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina Glaucoma Research Institute Wenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Wenzhou 325027Zhejiang ProvinceChina

AIM:To evaluate the trend of glaucoma internal filtration surgeries for inpatients between 2015 and 2021 at the Eye Hospital of Wenzhou Medical ***:A review of the medical records of inpatients who had been diagnosed with glaucoma and received antiglaucoma surgery between January 1,2015 and December 31,2021 was *** glaucoma diagnosis in this study included primary open angle glaucoma,primary angleclosure glaucoma,secondary glaucoma,and paediatric *** types of surgeries were categorised as internal filtration,external filtration,and cyclodestruction surgery based on the pathway of aqueous humor *** trend of these glaucoma surgeries in the sample of patients with different types of glaucoma was then ***:The number of patients hospitalised for glaucoma surgery increased yearly,from 752 in 2015 to 1373 in 2021,at the Eye Hospital of Wenzhou Medical *** the patients diagnosed with primary open angle glaucoma,internal filtration surgery increased from 27.40%of the sample to 54.40%of the sample,while external filtration surgery decreased from 71.50%to 44.20%between 2015 and *** paediatric glaucoma,internal filtration surgery increased from 37.50%in 2015 to 88.20%in *** different types of surgeries were performed on the sample of patients with secondary glaucoma,the proportion of internal filtration surgery also showed an increase from 18.20%in 2015 to 40.90%in ***,internal filtration surgery in the patient sample with primary angle-closure glaucoma already accounted for over 70.00%in 2015,and showed a small increase by ***:As surgical technology and surgical experience continue to elevate and improve,the range of glaucoma surgeries are correspondingly *** study find that internal filtration surgeries accounted for an increasing proportion of treatments in the surgical management of glaucoma between 2015 and 2021.

关键词： glaucoma internal filtration surgery inpatient trend

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Relationship between expression of chemokine receptors CCR3, CCR5 and CXCR3 on CD4^＋ T cells and spontaneous abortion in mice

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Chinese Medical Journal 2009年第4期122卷 390-395页

作者： JIANG pei-juan LIN Qi-de BAO Shi-min ZHAO Ai-min ZHANG Yu XIAO Shi-jin Department of Obstetrics and Gynecology Renji Hospital Schoolof Medicine Shanghai Jiao Tong University Shanghai 200127China Laboratory Animal Center of Shanghai Chinese Academy ofScience Shanghai 201615 China

Background Previous studies have shown that local immune cells in the feto-maternal interface are recruited from peripheral blood, and that chemokines and their receptors play an initial and key role in this recruitment process. In this study, we aimed to determine whether spontaneous abortion is associated with the expression of chemokine receptors CCR3, CCR5, and CXCR3 on CD4^＋ T cells. Methods Peripheral blood, spleen, and thymus were collected from the spontaneous abortion mouse model CBA/JxDBA/2 （SA group, n=14）, the normal pregnant mouse model CBA/JxBALB/c （NP group, n=13）, and normal non-pregnant CBA/J mice （NNP group, n=11）. The number of chemokine receptors CCR3, CCR5, and CXCR3 expressed on CD4^＋ T cells was measured by double-label flow cytometry （FCM） method. Results In peripheral blood, the SA group had significantly lower CCR3 expression （P 〈0.01） and higher CCR5 and CXCR3 expression （P 〈0.01） on CD4^＋ T cells than did the NP group. But comparing these chemokines between the SA and NNP groups, there was no significant difference （P 〉0.05）. In spleen, the SA group expressed significantly lower CCR3 expression （P 〈0.01） and higher CCR5 and CXCR3 expression （P 〈0.05） on CD4^＋ T cells than did the NP group. When compared with the NNP group, the SA group had significantly higher CCR3 expression （P 〈0.01）, but was not statistically different with regards to the other two chemokines （P 〉0.05）. In thymus, the SA group had significantly lower CCR3 expression （P 〈0.05） and higher CXCR3 expression （P 〈0.05） on CD4^＋ T cells than the NP group, with no significant difference in CCR5 expression （P 〉0.05）. Compared with the NNP group, the SA group had higher CCR3 expression （P 〈0.01）, but there was no statistical difference in CXCR3 and CCR5 expression （P 〉0.05） between the two groups. Conclusion The abnormal expression of CCR3, CCR5 and CXCR3 on CD4^＋ T cells may play an important role in the pathogenesis of spontaneous abortion.

关键词： receptors, CCR3, CCR5, CXCR3 CD4-positive T-lymphocytes abortion, spontaneous

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水稻转基因研究的竞争态势分析

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中国生物工程杂志 2015年第6期35卷 116-123页

作者：迟培娟吴鸣中国科学院文献情报中心北京100190

以科学引文索引SCIE数据库为数据源,下载水稻转基因研究领域的文献记录,利用TDA软件、Histcite软件和可视化工具Citespace,重点对1988年到2013年间的文献数据进行统计与分析。通过分析该领域的发文数量、发文期刊、主要研究机构、发文... 详细信息

以科学引文索引SCIE数据库为数据源,下载水稻转基因研究领域的文献记录,利用TDA软件、Histcite软件和可视化工具Citespace,重点对1988年到2013年间的文献数据进行统计与分析。通过分析该领域的发文数量、发文期刊、主要研究机构、发文作者和主题词,绘制可视化图谱,揭示水稻转基因研究领域的研究趋势、国家、机构、研究者以及研究热点和前沿,并以此帮助科研人员快速把握该研究领域的脉络和概貌。

关键词：水稻转基因态势分析 TDA Histcite Citespace JCR

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Grey Relational Analysis on the Effects of Rainfall Factors on Runoff and Sediment in the Sloping Farmland with Different Plants in the Central South of Shandong Province

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Meteorological and Environmental Research 2011年第8期2卷 52-55,81页

作者： LIU pei-juan ZHAO Zeng-li XING Yan YANG Ji-hua Zhucheng Water Resources and Aquatic Bureau Zhucheng 262200China Comprehensive Agricultural Service Center of Baichihe Town Zhucheng 262200China Zhucheng River Authority Zhucheng 262200China Soil and Water Conservation Department of Forestry College Shandong Agricultural UniversityTaian 271018China

[Objective] The aim was to study the main rainfall factors influencing runoff and sediment in the sloping farmland with different plants in the central south of Shandong Province.[Method] Through grey relational analysis,the effects of different rainfall factors on runoff and sediment with different plants in the central south of Shandong were studied.[Result] In the sloping farmland with different plants,the effects of rainfall factors on runoff and sediment weren’t *** was the dominant influencing factor of runoff,but PI30 had the greatest influence on runoff in natural ***,rainfall intensity was the main influencing factor of sediment,but PI had the greatest influence on sediment in Astragalus adsurgens *** compound factor had the minimal influence on runoff and sediment in Arachis hypogaea plot and natural *** *** ***,rainfall intensity had the minimal impact on runoff,but the compound factor had the least effect on sediment.[Conclusion] The study could provide theoretical references for the comprehensive control of slope soil erosion,the optimum utilization and sustainable development of land.

关键词： Rainfall factor Runoff Sediment Grey relation analysis China

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Histone deacetylase 3 promotes innate antiviral immunity through deacetylation of TBK1

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Protein & Cell 2021年第4期12卷 261-278页

作者： Jie-lin Tang Qi Yang Chong-hui Xu He Zhao Ya-ling Liu Can-yu Liu Yuan Zhou Dong-wei Gai Rong-juan pei Yun Wang Xue Hu Bo Zhong Yan-yi Wang Xin-wen Chen Ji-zheng Chen State Key Laboratory of Virology Wuhan Institute of VirologyCenter for Biosafety Mega-ScienceChinese Academy of SciencesWuhan 430071China University of Chinese Academy of Sciences Beijing 100049China Medical Research Institute School of MedicineWuhan UniversityWuhan 430071China Guangzhou Institutes of Biomedicine and Health Chinese Academy of SciencesGuangzhou 510530China

TANK-binding kinase 1(TBK1),a core kinase of antiviral pathways,activates the production of interferons(IFNs).It has been reported that deacetylation activates TBK1;however,the precise mechanism still remains to be *** show here that during the early stage of viral infection,the acetylation of TBK1 was increased,and the acetylation of TBK1 at Lys241 enhanced the recruitment of IRF3 to ***3 directly deacety-lated TBK1 at Lys241 and Lys692,which resulted in the activation of *** at Lys241 and Lys692 was critical for the kinase activity and dimerization of TBK1 *** knockout cell lines and transgenic mice,we confirmed that a HDAC3 null mutant exhibited enhanced susceptibility to viral challenge via impaired production of type I ***,activated TBK1 phosphorylated HDAC3,which promoted the deacetylation activity of HDAC3 and formed a feedback *** this study,we illustrated the roles the acetylated and deacetylated forms of TBK1 play in antiviral innate responses and clarified the post-trans-lational modulations involved in the interaction between TBK1 and HDAC3.

关键词： TBK1 HDAC3 deacetylation IRF3 innate immune

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氪激光联合Nd：YAG激光行激光虹膜切除术后一过性眼压升高发病机制

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国际眼科杂志 2017年第12期17卷 2222-2225页

作者：裴志娟新华医疗集团新华医院眼科中国安徽省淮南市232052

目的:研究氪激光联合Q-开关Nd∶YAG激光行激光虹膜切除术后一过性眼压升高的发病机制。方法:选取由本院动物实验中心提供的健康家兔42只84眼,其中雌兔18只,雄兔24只;平均质量2.24±0.31kg;随机分为6组,每组7只14眼,其中A、B、C、D、E组... 详细信息

目的:研究氪激光联合Q-开关Nd∶YAG激光行激光虹膜切除术后一过性眼压升高的发病机制。方法:选取由本院动物实验中心提供的健康家兔42只84眼,其中雌兔18只,雄兔24只;平均质量2.24±0.31kg;随机分为6组,每组7只14眼,其中A、B、C、D、E组分别为激光虹膜切除术后20min,2、6、18、24h组;F组为正常对照组。观察各组术前及术后眼压和房水内丙二醛(malondialdehyde,MDA)、一氧化氮(nitric oxide,NO)、超氧化物歧化酶(superoxide dismutase,SOD)、6-酮-前列腺素F_(1α)(6-酮-PGF1α)和一氧化氮合酶(nitric oxide synthase,NOS)含量的变化。结果:手术前各组眼压、房水内NO、NOS、SOD、MDA、6-酮-PGF1α含量对比差异均无统计学意义(P>0.05)。术后6h内眼压升高,A、B、C组分别与F组比较,差异均有统计学意义(P0.05)。术后房水内NO、NOS、SOD含量呈下降趋势,A、B、C组分别与F组比较,差异均有统计学意义(P0.05)。术后房水内MDA和6-酮-PGF1α含量呈上升趋势,A、B、C组分别与F组比较,差异均有统计学意义(P0.05)。结论:激光虹膜切除术后一过性眼压升高与术后房水内MDA、6-酮-PGF1α含量升高和SOD、NO降低相关。

关键词：氪激光激光虹膜切除术眼压升高房水

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长沙市商业街区单向交通组织的适应性评价

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湖南师范大学自然科学学报 2009年第4期32卷 108-113页

作者：朱佩娟湖南师范大学资源环境科学学院中国长沙410081

城市单向交通作为缓解城市交通拥堵问题的有效途径,在各大城市得到了广泛的应用,但是商业街区单行线的设置也产生了诸多负面影响.在分析城市商业街区交通组织中存在的主要问题的基础上,运用模糊综合评价法,对长沙市商业街区单向交通组... 详细信息

城市单向交通作为缓解城市交通拥堵问题的有效途径,在各大城市得到了广泛的应用,但是商业街区单行线的设置也产生了诸多负面影响.在分析城市商业街区交通组织中存在的主要问题的基础上,运用模糊综合评价法,对长沙市商业街区单向交通组织的商业适应性进行评价.认为城市交通管理部门应该从全局把握,慎重考虑单行线设置的必要性和可行性,使单行线设置的正面效应高于负面影响.对于商业利益的主体来说,应积极主动采取一定的措施来降低单行线的负面影响,适应商业新格局.

关键词：单向交通组织商业街区适应性长沙市

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APPLICATION OF FUZZY COMPREHENSIVE EVALUATION METHOD FOR EQUIPMENT MAINTENANCE SERVICE SELECTION OF MANUFACTURING ENTERPRISE

APPLICATION OF FUZZY COMPREHENSIVE EVALUATION METHOD FOR EQU...

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2005年中国机械工程学会年会

作者： pei juan, CHEN Xiaohui, LIANG Shukai (College of Mechanical Engineering, Chongqing University, Chongqing, 400030)

＜正＞Equipment maintenance outsourcing is one of the most important forms of enterprise resource outsourcing. The evaluation and selection of equipment maintenance service is one of the important problems that enterprises are faced with while wrapping up the equipment maintenance outside. The characteristics of equipment maintenance service are often portrayed by a lot of factors. It is a multi-objective decision problem essentially. This text constructed evaluation index system of equipment maintenance service, used Fuzzy Comprehensive Evaluation Method to queue and select the superior. The result can be regarded as important basis when the policymakers select the equipment maintenance service.

关键词： fuzzy comprehensive evaluation method maintenance service outsourcing

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含双吸电子基团的三苯胺染料在太阳电池中的应用

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物理化学学报 2008年第11期24卷 1950-1956页

作者：裴娟梁茂陈军陶占良许炜南开大学新能源材料化学研究所天津市能源材料化学重点实验室天津300071

合成了两种具有不同共轭链长度的双吸电子基团的三苯胺类染料TPAR3和TPAR6,研究了它们的光物理与光电化学性质,并将它们用作TiO2纳米晶电极的光敏化剂引入太阳电池.结果表明,与含有乙烯基共轭桥的染料TPAR3相比,含有丁二烯基共轭桥的染... 详细信息

合成了两种具有不同共轭链长度的双吸电子基团的三苯胺类染料TPAR3和TPAR6,研究了它们的光物理与光电化学性质,并将它们用作TiO2纳米晶电极的光敏化剂引入太阳电池.结果表明,与含有乙烯基共轭桥的染料TPAR3相比,含有丁二烯基共轭桥的染料TPAR6在甲醇溶液和TiO2膜上的最大吸收均发生一定程度的红移和宽化;但TPAR6表现出比TPAR3差的光电性能,主要是因为前者更易发生顺反异构化,电子不能够顺利地从染料激发态注入到TiO2导带中,光电流的产生得到抑制.考察了基于TPAR3的太阳电池在电解液中加入不同浓度的硫氰酸胍(GT)对光电性能的影响,发现在GT浓度为0.100mol·L-1时效率达到最大(4.02%).

关键词：三苯胺类染料胍盐太阳电池光电转化

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GIS在青岛市高层建筑空间布局专项规划中的应用

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测绘通报 2008年第4期 31-34页

作者：夏青马培娟青岛市城市规划设计研究院山东青岛266071

主要阐述用GIS的分析技术为高层建筑空间布局专项规划服务的过程,介绍GIS在管理决策及规划设计中的应用。

关键词： GIS 高层建筑数据库

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