检索结果-南通市图书馆

Collaborative learning via social computing

在线全文

学校读者我要写书评

暂无评论

Frontiers of Information Technology & Electronic Engineering 2019年第2期20卷 265-282页

作者： Ricardo S.ALONSO Javier PRIETO óscar GARCíA juan m.corchado BISITE Research Group University of Salamanca

Educational innovation is a field that has been greatly enriched by using technology in its processes, resulting in a learning model where information comes from numerous sources and collaboration takes place among multiple students. One attractive challenge within educational innovation is the design of collaborative learning activities from the social computing point of view, where collaboration is not limited to student-to-student relationships, but includes student-to-machine interactions. At the same time, there is a great lack of tools that give support to the whole learning process and are not restricted to specific aspects of the educational task. In this paper, we present and evaluate context-aware framework for collaborative learning applications(CAFCLA) as a solution to these problems. CAFCLA is a flexible framework that covers the entire process of developing collaborative learning activities, taking advantage of contextual information and social interactions. Its application in the experimental case study of a collaborative WebQuest within a museum has shown that, among other benefits, the use of social computing improves the learning process, fosters collaboration, enhances relationships, and increases engagement.

关键词： Context-awareness Collaborative learning Social computing Virtual organizations Wireless sensor networks Real time location system

Approximate Gaussian conjugacy： parametric recursive filtering under nonlinearity, multimodality, uncertainty, and constraint, and beyond

在线全文

学校读者我要写书评

暂无评论

Frontiers of Information Technology & Electronic Engineering 2017年第12期18卷 1913-1939页

作者： Tian-cheng LI Jin-ya SU Wei LIU juan m.corchado School of Sciences University of Salamanca Department of Aeronautical and Automotive Engineering Loughborough University Department of Electronic and Electrical Engineering University of Sheffield

自上世纪60年代作为现代估计开山之作的卡尔曼滤波器(Kalman filter)的诞生,时间序列状态空间模型应用于各类动态估计问题吸引了大量的研究关注。特别是,寻求实现闭环马尔科夫-贝叶斯递归(比如,从一个高斯先验到一个高斯后验,本文称之... 详细信息

自上世纪60年代作为现代估计开山之作的卡尔曼滤波器(Kalman filter)的诞生,时间序列状态空间模型应用于各类动态估计问题吸引了大量的研究关注。特别是,寻求实现闭环马尔科夫-贝叶斯递归(比如,从一个高斯先验到一个高斯后验,本文称之为高斯共轭)的解析解成为一般时间序列滤波器设计的主流思路。其面临的主要挑战包括:系统的非线性、多模态(包括机动模型)、复杂不确定性(比如未知的系统输入,非高斯噪声等)和系统约束(包括循环随机变量)等。这些挑战不断触生新的理论、算法与滤波技术,以实现所期望的参数共轭递归。本文对最新研究进行分类、系统回顾,强调了一些容易被忽略的要点。着重介绍了高精观测非线性系统、高斯后验和机动多模态、以及复杂未知系统输入与约束,以弥补当前文献介绍的不足。同时,本文提出一些新的思考:一是一阶马尔科夫转移模型的替代模型,二是有关计算复杂度的滤波器评价。

关键词：卡尔曼滤波高斯滤波时间序列估计贝叶斯滤波非线性滤波约束滤波高斯混合机动未知输入

Editorial:Special issue on distributed computing and artificial intelligence

在线全文

学校读者我要写书评

暂无评论

Frontiers of Information Technology & Electronic Engineering 2016年第4期17卷 281-282页

作者： juan m.corchado Li WEIGANG Javier BAJO Fei WU Tian-cheng LI University of Salamanca Spain University of Brasilia Brazil Polytechnic University of madrid Spain Zhejiang University China

4:1!Google’s artificial intelligence(AI)program,Alpha Go,has won Go master Lee Sedol in a best-of-five competition held in Korean march 9-15,2016.Seen by many as a landmark moment for AI,the outcome did not come as a... 详细信息

关键词：人工智能分布式计算编辑计算机科学分布式环境智能算法优良组合蒙特卡洛

Single-neuron neurodegeneration as a degenerative model for Parkinson’s disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第3期19卷 529-535页

作者： Sandro Huenchuguala juan Segura-Aguilar Escuela de Tecnología médica Facultad de SaludUniversidad Santo TomásLos CarrerasOsornoChile molecular&Clinical Pharmacology Instituto de Ciencias Biomedicas(ICBM)Faculty of medicineUniversity of ChileIndependenciaSantiagoChile

The positive effect of levodopa in the treatment of Parkinson’s disease,although it is limited in time and has severe side effects,has encouraged the scientific community to look for new drugs that can stop the neurodegenerative process or even regenerate the neuromelanin-containing dopaminergic nigrostriatal neurons.Successful preclinical studies with coenzyme Q10,mitoquinone,isradipine,nilotinib,TCH346,neurturin,zonisamide,deferiprone,prasinezumab,and cinpanemab prompted clinical trials.However,these failed and after more than 50 years levodopa continues to be the key drug in the treatment of the disease,despite its severe side effects after 4–6 years of chronic treatment.The lack of translated successful results obtained in preclinical investigations based on the use of neurotoxins that do not exist in the human body as new drugs for Parkinson’s disease treatment is a big problem.In our opinion,the cause of these failures lies in the experimental animal models involving neurotoxins that do not exist in the human body,such as 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 6-hydroxydopamine,that induce a very fast,massive and expansive neurodegenerative process,which contrasts with the extremely slow one of neuromelanin-containing dopaminergic neurons.The exceedingly slow progress of the neurodegenerative process of the nigrostriatal neurons in idiopathic Parkinson’s patients is due to(i)a degenerative model in which the neurotoxic effect of an endogenous neurotoxin affects a single neuron,(ii)a neurotoxic event that is not expansive and(iii)the fact that the neurotoxin that triggers the neurodegenerative process is produced inside the neuromelanin-containing dopaminergic neurons.The endogenous neurotoxin that fits this degenerative model involving one single neuron at a time is aminochrome,since it(i)is generated within neuromelanin-containing dopaminergic neurons,(ii)does not cause an expansive neurotoxic effect and(iii)triggers all the mechanisms involved in the neurodegenerative process of the nigrostriata

关键词： 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 6-hydroxydopamine aminochrome dopaminergic neurons DT-diaphorase exogenous neurotoxins glutathione transferase m2-2

粒子滤波重采样:同分布原则、一种新方法以及综合对比(英文)

在线全文

学校读者我要写书评

暂无评论

Frontiers of Information Technology & Electronic Engineering 2015年第11期16卷 969-984页

作者： Tian-cheng LI Gabriel VILLARRUBIA Shu-dong SUN juan m.corchado Javier BAJO BISITE Group Faculty of Science University of Salamanca School of mechanical Engineering Northwestern Polytechnical University Osaka Institute of Technology Department of Artificial Intelligence Technical University of Madrid

目的:重采样方法是粒子滤波设计的重要环节,也是避免或克服"权值退化"和"多样性匮乏"这一对粒子滤波难点问题的关键。当前研究领域已有几十余种重采样方法,然而尚缺乏一个基础性的重采样设计原则以及对这些方法的综合性能对比。针对于此... 详细信息

目的:重采样方法是粒子滤波设计的重要环节,也是避免或克服"权值退化"和"多样性匮乏"这一对粒子滤波难点问题的关键。当前研究领域已有几十余种重采样方法,然而尚缺乏一个基础性的重采样设计原则以及对这些方法的综合性能对比。针对于此,本文提出重采样"同分布"设计原则,并在此基础上,提出一种能够最大程度满足同分布原则的最优重采样方法。本文希望所提出的重采样同分布原则以及新方法有利于进一步的新方法设计或已有方法的工程选用。创新点:理论上严格定义了同分布原则作为重采样方法设计的普遍性原则,给出三种同分布测度方法;提出了一种最小采样方差(mSV:minimum sampling variance)最优重采样方法,在满足渐近无偏性的前提下获得最小采样方差。方法:给出三种"重采样同分布"测度方法:Kullback-Leibler偏差,Kolmogorov-Smirnov统计和采样方差(sampling variance)。所提出的最小采样方差重采样放宽了无偏性条件,仅满足渐近无偏,但获得了最小采样方差(参见定理2-4论证以及仿真性能对比)。结论:重采样前后粒子的概率分布应该统计上一致(即"同分布")是重采样方法设计的一个重要原则。明确这一基本原则有利于规范化重采样新方法的设计与工程选用。所提出的mSV重采样新方法渐近无偏,并具有最小采样方差的优异理论特性,即最优地满足同分布原则。算法性能分析表明:大多数无偏或者渐近无偏重采样方法在滤波精度上差异较小,但是在采样方差、计算效率方面差异较大。另一方面,基于一些特殊规则或者问题模型设计的重采样方法可能具有特别优势。

关键词：粒子滤波重采样统计同分布采样方差

Attractor for the Extensible Beam Equation with Nonlocal Weak Damping on Time–Dependent Space

在线全文

学校读者我要写书评

暂无评论

Acta mathematica Sinica,English Series 2024年第4期40卷 1115-1126页

作者： Chun Xiang ZHAO Feng juan mENG Institute of Applied System Analysis Jiangsu UniversityZhenjiang 212013P.R.China School of mathematics and Physics Jiangsu University of TechnologyChangzhou 213001P.R.China

In this article,we consider the long-time behavior of extensible beams with nonlocal weak damping:ε(t)u_(tt)+Δ^(2)u-m(‖▽u‖^(2))Δu+‖u_(t)‖^(p_(u_(t)))+f(u)=h,whereε(t)is a decreasing function vanishing at infinity.Within the theory of process on time-dependent spaces,we investigate the existence of the time-dependent attractor by using the Condition(C_(t))method and more detailed estimates.The results obtained essentially improve and complete some previous works.

关键词： Time-dependent attractor extensible beams equation nonlocal weak damping

Application of Global Leadership Initiative on malnutrition criteria in patients with liver cirrhosis

在线全文

学校读者我要写书评

暂无评论

Chinese medical Journal 2024年第1期137卷 97-104页

作者： minjie Jiang juan Chen muchen Wu Jing Wu Xiaotong Xu juan Li Can Liu Yaping Zhao Xin Hua Qinghua meng Department of Hepatology Beijing You-An HospitalCapital Medical UniversityBeijing 100069China Beijing Institute of Hepatology Beijing 100069China Department of medical Oncology Beijing You-An HospitalCapital Medical UniversityBeijing 100069China Department of Nutrition Beijing You-An HospitalCapital Medical UniversityBeijing 100069China

Background:The Global Leadership Initiative on malnutrition(GLIm)criteria were published to build a global consensus on nutritional diagnosis.Reduced muscle mass is a phenotypic criterion with strong evidence to support its inclusion in the GLIm consensus criteria.However,there is no consensus regarding how to accurately measure and define reduced muscle mass in clinical settings.This study aimed to investigate the optimal reference values of skeletal muscle mass index for diagnosing sarcopenia and GLIm-defined malnutrition,as well as the prevalence of GLIm-defined malnutrition in hospitalized cirrhotic patients.methods:This retrospective study was conducted on 1002 adult patients with liver cirrhosis between January 1,2018,and February 28,2022,at Beijing You-An Hospital,Capital medical University.Adult patients with a clinical diagnosis of liver cirrhosis and who underwent an abdominal computed tomography(CT)examination during hospitalization were included in the study.These patients were randomly divided into a modeling group(cohort 1,667 patients)and a validation group(cohort 2,335 patients).In cohort 1,optimal cut-off values of skeletal muscle index at the third lumbar skeletal muscle index(L3-SmI)were determined using receiver operating characteristic analyses against in-hospital mortality in different gender groups.Next,patients in cohort 2 were screened for nutritional risk using the Nutritional Risk Screening 2002(NRS-2002),and malnutrition was diagnosed by GLIm criteria.Additionally,the reference values of reduced muscle mass in GLIm criteria were derived from the L3-SmI values from cohort 1.multivariate logistic regression analysis was used to analyze the association between GLIm-defined malnutrition and clinical outcomes.Results:The optimal cut-off values of L3-SmI were 39.50 cm 2/m 2 for male patients and 33.06 cm 2/m 2 for female patients.Based on the cut-off values,31.63%(68/215)of the male patients and 23.3%(28/120)of the female patients had CT-determined sarcopenia in cohort 2.The prevalence of GL

关键词： malnutrition Liver cirrhosis Sarcopenia Clinical outcomes GLIm criteria

Review of Networked microgrid Protection:Architectures,Challenges,Solutions,and Future Trends

在线全文

学校读者我要写书评

暂无评论

CSEE Journal of Power and Energy Systems 2024年第2期10卷 448-467页

作者： Jorge de la Cruz Ying Wu John E.Candelo-Becerra juan C.Vasquez Josep m.Guerrero Center for Research on microgrids(CROm) Department of Energy TechnologyAalborg University9220 AalborgDenmark Facultad de minas Departamento de Energia Eléctrica y AutomaticaUniversidad Nacional de ColombiaSede MedellinCarrera 80 No.65-223RobledoMedellin 050041Colombia. Center for Research on microgrids at UPC(UPC CROm) Department of Electronic EngineeringTechnical University of Catalonia(UPC)08019 Barcelona Spain ICREA Pg.Lluis Companys 2308010 BarcelonaSpain Center for Research on microgrids at AAU(AAU CROm) AAU EnergyAalborg University(AAU)9220 Aalborg EastDenmark

Design and selection of advanced protection schemes have become essential for reliable and secure operation of networked microgrids.Various protection schemes that allow correct operation of microgrids have been proposed for individual systems in different topologies and connections.Nevertheless,protection schemes for networked microgrids are still in devel-opment,and further research is required to design and operate advanced protection in interconnected systems.Interconnection of these microgrids in different nodes with various intercon-nection technologies increases fault occurrence and complicates protection operation.This paper aims to point out challenges in developing protection for networked microgrids,potential solutions,and research areas that need to be addressed for their development.First,this article presents a systematic analysis of different microgrid clusters proposed since 2016,including several architectures of networked microgrids,operation modes,components,and utilization of renewable sources,which have not been widely explored in previous review papers.Second,the paper presents a discussion on protection systems currently available for microgrid clusters,current challenges,and solutions that have been proposed for these systems.Finally,it discusses the trend of protection schemes in networked microgrids and presents some conclusions related to implementation.IndexTerms—Adaptive eprotection,microgrid cluster,microgrid,multiple microgrid,networked microgrid,real-time simulation,smart grid.

关键词： Adaptive eprotection microgrid cluster microgrid multiple microgrid networked microgrid real-time simulation smart grid

Novel insights into D-Pinitol based therapies:a link between tau hyperphosphorylation and insulin resistance

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第2期19卷 289-295页

作者： Dina medina-Vera Antonio Jesús López-Gambero juan Antonio Navarro Carlos Sanjuan Elena Baixeras juan Decara Fernando Rodríguez de Fonseca Instituto de Investigación Biomédica de málaga y Plataforma en Nanomedicina-IBImA Plataforma BIONAND UGC Salud MentalMálagaSpain Facultad de Ciencias Universidad de MálagaMálagaSpain CIBER Enfermedades Cardiovasculares(CIBERCV) Hospital Universitario Virgen de la VictoriaUGC del CorazónMálagaSpain University of Bordeaux INSERMNeurocentre MagendieBordeauxFrance Euronutra S.L.Calle Johannes Kepler MálagaSpain Departamento de Bioquímica y Biología molecular Facultad de MedicinaUniversidad de MálagaMálagaSpain

Alzheimer’s disease is a neurodegenerative disorder characterized by the amyloid accumulation in the brains of patients with Alzheimer’s disease.The pathogenesis of Alzheimer’s disease is mainly mediated by the phosphorylation and aggregation of tau protein.Among the multiple causes of tau hyperphosphorylation,brain insulin resistance has generated much attention,and inositols as insulin sensitizers,are currently considered candidates for drug development.The present narrative review revises the interactions between these three elements:Alzheimer’s disease-tau-inositols,which can eventually identify targets for new disease modifiers capable of bringing hope to the millions of people affected by this devastating disease.

关键词： Alzheimer’s disease cyclin-dependent kinase 5 diabetes D-Pinitol inositols insulin resistance kinases phosphorylation PI3K/Akt tau