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Helicobacter pylori recurrence after eradication in Latin America:Implications for gastric cancer prevention

World Journal of Gastrointestinal Oncology 2017年第4期9卷 184-193页

作者： juan e corral Robertino Mera Corey W Dye Douglas R Morgan Division of Gastroenterology and Hepatology Mayo Clinic Division of Gastroenterology Hepatologyand NutritionVanderbilt University Department of Medicine University of Miami Miller School of Medicine

To estimate Helicobacter pylori (H. pylori) recurrence rate in Latin America, a region with a significant H. pylori prevalence and gastric cancer burden. MeTHODSPubMed, LILACS, ScieLO, Cochrane databases and abstracts from relevant meetings were reviewed. Information collected included: Participants’ characteristics, recruitment strategy, diagnostic modality, treatment arms, follow-up and recurrence rates. Recurrence was calculated using 100-patients-year rates, and data were pooled using a random effects model. The I2 statistic assessed between study heterogeneity. Meta-regression analyses evaluated for effect modifying variables. ReSULTSLiterature search yielded 163 articles. Twelve studies involving 4848 patients from 9 countries met inclusion criteria. Four hundred and thirty-two reinfections were recorded in 5487 person-years of follow-up. Pooled analysis showed a recurrence rate of 7.9 cases per 100 person-years (95%CI: 5.3-10.5). Meta-regression revealed that neither the antibiotic schema, a second antibiotic course, nor the diagnostic modality had an impact on the observed risk of recurrence. The recurrence rate in the first year after treatment, predominantly recrudescence, was 11.2 (6.1-16.4) per 100 patient years. Recurrence in subsequent years, was only 6.2 (3.8-8.7). CONCLUSIONH. pylori recurrence rates in Latin America are significant, and with geographic variability, yet are acceptable based upon the current literature for consideration of large scale intervention trials. Further research in Latin America is warranted to evaluate the efficacy, cost-effectiveness, and potential adverse outcomes of proposed eradication programs.

关键词： Gastric cancer Reinfection Hispanic Helicobacter pylori Latin America

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COMPLeX CONCePT LATTICeS FOR SIMULATING HUMAN PReDICTION IN SPORT

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Journal of Systems Science & Complexity 2013年第1期26卷 117-136页

作者： ARANDA-corral Gonzalo A BORReGO-DíAZ Joaquín GALáN-PáeZ juan Universidad de Huelva.Department of Information Technology Crta.Palos de La Frontera s/n.21819 Palos de La Frontera Universidad de Sevilla.Department of Computer Science and Artificial Intelligence Avda.Reina Mercedes s/n.41012 Sevilla

In order to address the study of complex systems,the detection of patterns in their dynamics could play a key role in understanding their *** particular,global patterns are required to detect emergent concepts and trends,some of them of a qualitative *** concept analysis(FCA) is a theory whose goal is to discover and extract knowledge from qualitative data(organized in concept lattices).In complex environments,such as sport competitions,the large amount of information currently available turns concept lattices into complex *** authors analyze how to apply FCA reasoning in order to increase confidence in sports predictions by means of detecting regularities from data through the management of intuitive and natural attributes extracted from publicly available *** complexity of concept lattices-considered as networks with complex topological structure- is *** is applied to building a knowledge based system for confidence-based reasoning,which simulates how humans tend to avoid the complexity of concept networks by means of bounded reasoning skills.

关键词： Bounded rationality complex networks formal concept analysis sport forecasting.

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The USLe soil erodibility nomograph revisited

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International Soil and Water Conservation Research 2023年第1期11卷 1-13页

作者： eva corral-Pazos-de-Provens ígor Rapp-Arraras juan M.Domingo-Santos School of engineering University of HuelvaE-21007 HuelvaSpain

The nomograph by Wischmeier et al.(1971)for calculating the K-factor in the USLe was extremely useful when there was low access to ***,the generalised calculation of this factor requires the development of analytic *** paper presents a detailed analysis of the nomograph and its underlying equation,which is applicable only when the silt plus very find sand fraction does not exceed 70%.We also examined the quality of fit on the nomograph of the adaptations to the equation that have been proposed,as a means of dealing with those areas where the original equation is not *** models are shown to have areas where the fit is deficient or even ***,the family of curves on the nomograph for the various values taken by the organic matter are not coincident with the mathematical function from which they presumably *** study also identifies those areas of the textural triangle in which the soils originally used in developing the USLe are located,with a view to according a lower predictive value to the contrasting areas in which calculations of the K-factor will necessarily be ***,a new equation for calculating the K-factor is presented,which accurately reproduces the different sections of the nomograph,and allows the poorly functioning graph to be dispensed *** paper ends with a link to a tool in R for simplifying the procedure for calculating the K-factor,taking into account varying situations of data availability.

关键词： K-factor RUSLe Soil texture Organic matter Very find sand Soil loss prediction

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Local and generalized height-diameter models with random parameters for mixed,uneven-aged forests in Northwestern Durango,Mexico

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Forestry Studies in China 2014年第1期16卷 41-49页

作者： Sacramento corral-Rivas juan Gabriel lvarez-González Felipe Crecente-Campo José Javier corral-Rivas Instituto Tecnológico de eI Salto Mesa del Tecnologico s/n.Apdo.Postal No.2EI Salto P.N.34950DurangoMéxico Departamento de Ingenieria Agroforestal Universidad de Santiago de Compostela.Escuela Politécnica SuperiorCampus Universitario27002 LugoEspana lnstituto de Silvicultura e Industria de la Madera Universidad Jurez del Estado de DurangoBlvd.del Guadiana # 501.Cuidad Universitaria34160 DurangoMexico

Background:We used mixed models with random components to develop height-diameter(h-d) functions for mixed,uneven-aged stands in northwestern Durango(Mexico),considering the breast height diameter(d) and stand variables as ***:The data were obtained from 44 permanent plots used to monitor stand growth under forest management in the study ***:The generalized Bertalanffy-Richards model performed better than the other generalized models in predicting the total height of the species under *** the genera Pinus and Quercus,the models were successfully calibrated by measuring the height of a subsample of three randomly selected trees close to the mean d,whereas for species of the genera Cupressus,Arbutus and Alnus,three trees were also selected,but they are specifically the maximum,minimum and mean d ***:The presented equations represent a new tool for the evaluation and management of natural forest in the region.

关键词： Conifer and broadleaves forests h-d relationship Mixed models Calibration

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CONSeNSUS AND r-CONSeNSUS PROBLeMS FOR SINGULAR SYSTeMS

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Journal of Systems Science & Complexity 2014年第2期27卷 252-262页

作者： ZHANG Lequn FeNG Jun-e YAO juan School of Mathematics Shandong University

In this paper, the problem of consensus for continuous time singular systems of multi-agent networks is considered. The definition of r-consensus is introduced for singular systems of multi-agent networks. Firstly, linear systems with algebraic constraints are considered, and the corresponding results about consensus and average-consensus are derived. Then r-consensus and consensus problems of singular systems are investigated. Sufficient conditions of r-consensus and consensus are obtained,respectively. Finally, an illustrative example is given to show the effectiveness of the proposed method.

关键词： Balanced graphs consensus r-consensus singular systems strong connected graphs.

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A bibliometric review of cryptocurrencies:how have they grown?

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Financial Innovation 2022年第1期8卷 25-55页

作者： Francisco Javier García-corral JoséAntonio Cordero-García Jaime de Pablo-Valenciano juan Uribe-Toril Research Group:Almeria Group of Applied economy(SeJ 147) University of AlmeriaCarretera Sacramento s/n04120La Cañada de San UrbanoAlmeríaSpain Department of Law Financial and Tax LawUniversity of AlmeriaCarretera Sacramento s/n04120La Cañada de San UrbanoAlmeríaSpain Department of Business and economics Applied Economic AreaUniversity of AlmeríaCarretera Sacramento s/n04120La Cañada de San UrbanoAlmeríaSpain

With the development of new technologies,some concepts become relevant in the economic area,as is the case with cryptocurrencies,in general,or Bitcoin and ethereum,in *** to the impact of these tools,a detailed bibliometric study that allows us to obtain all information about cryptocurrencies must be *** study will help scientific production by specifying the development and lines of related research that have been followed and are currently being *** have used Tableau,R(Bibliometrix R Package),and VOSviewer software to analyze the *** have been combined to create and review unified metadata from the Web of Science(WoS)and Scopus *** bibliometric analysis shows 771 articles on the WoS database and 648 articles on Scopus published between 2010 and early *** present the most relevant articles,research areas,countries,institu-tions,authors,journals,and trends during the last few *** conclusion,the number of publications has grown in the last 3 *** analysis shows the evolution of block-chain technology used in this type of *** review of this period marks a possible end to the historical part of cryptocurrencies,thereby opening the current topic to its multiple applications.

关键词： Cryptocurrency Bitcoin ethereum Bibliometric analysis Business and economics

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Real-time hybrid simulation for structural control performance assessment

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earthquake engineering and engineering Vibration 2009年第4期8卷 481-492页

作者： juan e Carrion BF Spencer Jr Brian M Phillips Skidmore Owings & Merrill LLP Civil and environmental engineering Department University of Illinois

Real-time hybrid simulation is an attractive method to evaluate the response of structures under earthquake loads. The method is a variation of the pseudodynamic testing technique in which the experiment is executed in real time, thus allowing investigation of structural systems with rate-dependent components. Real-time hybrid simulation is challenging because it requires performance of all calculations, application of displacements, and acquisition of measured forces, within a very small increment of time. Furthermore, unless appropriate compensation for actuator dynamics is implemented, stability problems are likely to occur during the experiment. This paper presents an approach for real-time hybrid simulation in which compensation for actuator dynamics is implemented using a model-based feedforward compensator. The method is used to evaluate the response of a semi-active control of a structure employing an MR damper. experimental results show good agreement with the predicted responses, demonstrating the effectiveness of the method for structural control performance assessment.

关键词： real-time hybrid simulation MR damper semi-active control actuator dynamics

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Outcomes of abdominal surgery in patients with liver cirrhosis

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World Journal of Gastroenterology 2016年第9期22卷 2657-2667页

作者： juan C Lopez-Delgado Josep Ballus Francisco esteve Nelson L Betancur-Zambrano Vicente corral-Velez Rafael Manez Antoni J Betbese Joan A Roncal Casimiro Javierre Hospital Universitari de Bellvitge Intensive Care Department L'Hospitalet de Llobregat 08907 Barcelona Spain IDIBeLL (Institut d'Investigacio Biomedica Bellvitge Biomedical Investigation Institute of Bellvitge) Research Team of Area of Innate Immunity and Pathology of the Critical Patient L'Hospitalet de Llobregat 08908 Barcelona Spain Hospital de la Santa Creu i Sant Pau Intensive Care Department 08041 Barcelona Spain Physiological Sciences II Department Universitat de Barcelona Campus Bellvitge 08907 Barcelona Spain

Patients suffering from liver cirrhosis(LC) frequently require non-hepatic abdominal surgery,even before liver *** is an important risk factor itself for surgery,due to the higher than average associated morbidity and *** high surgical risk occurs because of the pathophysiology of liver disease itself and to the presence of contributing factors,such as coagulopathy,poor nutritional status,adaptive immune dysfunction,cirrhotic cardiomyopathy,and renal and pulmonary dysfunction,which all lead to poor *** evaluation of these factors and the degree of liver disease can help to reduce the development of complications both during and after abdominal *** the emergency setting,with the presence of decompensated LC,alcoholic hepatitis,severe/advanced LC,and significant extrahepatic organ dysfunction conservative management is preferred.A multidisciplinary,individualized,and specialized approach can improve outcomes;preoperative optimization after risk stratification and careful management are mandatory before *** techniques can also improve *** review the impact of LC on surgical outcome in non-hepatic abdominal surgeries required in this cirrhotic population before,during,and after surgery.

关键词： Liver cirrhosis Outcomes Coagulopathy Nutritional status Abdominal surgery Adaptive immune dysfunction Cirrhotic cardiomyopathy

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Consequences of early life stress on the structure and function of the adult mouse retina

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Neural Regeneration Research 2024年第1期19卷 150-151页

作者： juan S.Calanni Ruth e.Rosenstein Laboratory of Retinal Neurochemistry and experimental Ophthalmology Department of Human BiochemistrySchool of Medicine/CEFyBOUniversity of Buenos Aires/CONICETBuenos AiresArgentina

early-life stress(eLS)refers to a period of environmental/social deprivation,physica l,sexual or emotional abuse,neglect,severe and/or chronic trauma in the prenatal/early postnatal stage,which is closely related to many adverse psychiatric disorders later in life,such as depressive disorder,substance abuse,dysthymia,panic,anxiety,and suicidal behavior in adulthood(Waters and Gould,2022).

关键词： stress life Gould

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Molecular targets and mechanisms of Jiawei Jiaotai Pill on diabetic cardiomyopathy based on network pharmacology

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World Journal of Diabetes 2023年第11期14卷 1659-1671页

作者： Yu-juan Wang Yan-Li Wang Xiao-Fan Jiang juan-e Li Department of Otolaryngology Shaanxi Provincial People’s HospitalXi’an 710068Shaaxi ProvinceChina Department of Pediatrics Affiliated Hospital of Traditional Chinese MedicineXinjiang Medical UniversityUrumqi 830000Xinjiang Uygur Autonomous RegionChina Department of Chinese Medicine Shaanxi Provincial People’s HospitalXi’an 710068Shaaxi ProvinceChina

BACKGROUND Jiawei Jiaotai Pill is commonly used in clinical practice to reduce apoptosis,increase insulin secretion,and improve blood glucose ***,its mechanism of action in the treatment of diabetic cardiomyopathy(DCM)remains unclear,hindering research efforts aimed at developing drugs specifically for the treatment of *** To explore the pharmacodynamic basis and molecular mechanism of Jiawei Jiaotai Pill in DCM *** We explored various databases and software,including the Traditional Chinese Medicine Systems Pharmacology Database,Uniport,PubChem,GenCards,String,and Cytoscape,to identify the active components and targets of Jiawei Jiaotai Pill,and the disease targets in ***-protein interaction network,gene ontology,and Kyoto encyclopedia of Genes and Genomes analyses were used to determine the mechanism of action of Jiawei Jiaotai Pill in treating *** docking of key active components and core targets was verified using AutoDock *** Total 42 active ingredients and 142 potential targets of Jiawei Jiaotai Pill were *** were 100 common targets between the DCM and Jiawei Jiaotai *** this screening process,TNF,IL6,TP53,eGFR,INS,and other important targets were *** targets are mainly involved in the positive regulation of the mitogen-activated protein kinase(MAPK)MAPK cascade,response to xenobiotic stimuli,response to hypoxia,positive regulation of gene expression,positive regulation of cell proliferation,negative regulation of the apoptotic process,and other biological *** was mainly enriched in the AGe-RAGe signaling pathway in diabetic complications,DCM,PI3K-Akt,interleukin-17,and MAPK signaling *** docking results showed that Jiawei Jiaotai Pill's active ingredients had good docking activity with DCM's core *** The active components of Jiawei Jiaotai Pill may play a role in the treatment of DCM by reducing oxidative stress,cardiomyocyt

关键词： Jiawei Jiaotai pill Diabetic cardiomyopathy Mechanism of action enrichment analysis Network pharmacology Molecular docking

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