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Clinical outcomes of patterned laser trabeculoplasty as adjuvant therapy in open angle glaucoma and ocular hypertension

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International Journal of Ophthalmology(English edition) 2018年第4期11卷 635-640页

作者： Gustavo Espinoza Leonardo Castellanos Ignacio Rodriguez-Una Paul Anthony Camacho juan camilo parra Fundacion Oftalmologica de Santander FOSCAL FloridablancaSantanderColombia Instituto Oftalmologico Fernandez-Vega University of OviedoOviedoAsturias 33012Spain Facultad de Salud Universidad Autonoma de BucaramangaBucaramangaSantanderColombia

AIM： To assess the efficacy and safety of patterned laser trabeculoplasty（PLT） as an adjunctive treatment in open angle glaucoma（OAG） or ocular hypertension（OHT） patients who were under antiglaucoma medical ***： This study was a retrospective review of primary or secondary OAG patients and OHT patients with medically uncontrolled（≥18 mm Hg） intraocular pressure（IOP） who underwent 360o PLT from June 2016 to August 2016. Follow-up visits at week 1, and 1, 3 and 6 mo were performed. IOP, best corrected visual acuity（BCVA）, complications and eye drop glaucoma medication were recorded at each follow-up visit. Success was defined as IOP reduction ≥20% from baseline. RESULTS： Forty-one eyes of 25 patients were included in this study. Pre-treatment mean IOP was 20.2±1.6 mm Hg. After PLT, IOP was 19.3±5.2, 16.1±2.7, 17.1±3.7 and 16.3±3.5 mm Hg,at 1 wk, 1, 3 and 6 mo, respectively. IOP reduction from baseline was statistically significant from the first month, remaining stable at 6 mo（P〈0.001）. PLT success at 6 mo of follow-up was 48.78%. The number of glaucoma medication per eye（P=0.10） and the mean BCVA both remained constant（P=0.37）. Complications included transient IOP spikes in 4 eyes（9.8%） and peripheral anterior synechiae in 7 eyes（17.1%）. CONCLUSION： PLT is an effective and safe method for the management of patients with OHT or OAG as an adjunctive therapy. Additional larger studies should be designed to verify the long-term stability of IOP reduction with this laser technology.

关键词： glaucoma intraocular pressure laser ocular hypertension trabeculoplasty

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Mid-term results of patterned laser trabeculoplasty for uncontrolled ocular hypertension and primary open angle glaucoma

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International Journal of Ophthalmology(English edition) 2021年第8期14卷 1199-1204页

作者： Gustavo Espinoza Yuly Andrea Castellanos-Castellanos Angelica Pedraza-Concha Ignacio Rodriguez-Una Maria Fernanda Acuna juan camilo parra Centro Oftalmologico Virgilio Galvis BucaramangaSantander 681004Colombia Fundacion Oftalmologica de Santander BucaramangaSantander 681004Colombia Universidad Industrial de Santander BucaramangaSantander 680002Colombia Instituto Oftalmologico Fernandez-Vega Universidad de OviedoOviedo 33012Spain

AIM:To describe the safety and efficacy of patterned laser trabeculoplasty(PLT)as an adjunctive treatment in primary open angle glaucoma(POAG)and ocular hypertension(OHT)after 18-month follow-up in Hispanic ***:A single-center,retrospective study was *** patients with OHT or POAG undergoing PLT from June 2016 to August 2016 were included in the *** parameters were intraocular pressure(IOP),the number of IOP-lowering medications,best corrected visual acuity(BCVA),laser parameters and postoperative adverse *** efficacy outcome measures were the proportion of eyes achieving an IOP reduction≥20%at 18 mo versus baseline medicated IOP or a reduction in the number of medications while maintaining IOP ***:From 40 PLT-treated eyes(mean baseline IOP 20.3±1.7 mm Hg),24 patients were analyzed(age 63.4±7.3 y).The mean IOP reductions from baseline across visits(months 1,3,6,9,12,and 18)ranged from 14.1%to 20.8%.Success rate after 18-month follow-up was 61.7%with a mean IOP of 16±3.2 mm Hg(P<0.001).The number of glaucoma IOP-lowering medications per eye(preoperative 2.1±1.1 and postoperative 2.3±1.1,P=0.86)and the mean BCVA(preoperative 0.10±0.22 and postoperative 0.11±0.22 logMAR,P=0.42)remained *** events comprised transitory IOP spikes in 4 eyes(10%)and peripheral anterior synechiae in 7 eyes(17.5%).CONCLUSION:Mid-term results of PLT show that this procedure may be an efficacious and safe technique to approach medically uncontrolled OHT or POAG patients.

关键词： glaucoma intraocular pressure ocular hypertension patterned laser trabeculoplasty

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Experimental analysis of infragravity waves in two eroded microtidal beaches

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Acta Oceanologica Sinica 2017年第5期36卷 31-43页

作者： MARIO Conde-Frias LUIS Otero juan camilo Restrepo juan Carlos Ortiz Geosciences Research Group GE04 Department of PhysicsUniversidad del NorteBarranquilla 081007Colombia

This work aims to contribute to the characterization and understanding ofinfragravity waves on two beaches with erosion problems. For this reason, we have used an array of ADCP and a pressure sensor to measure wave parameters and pressure inside and outside of the surf zone during the dry and rainy period in the beaches of Galerazamba and Manzanillo del Mar （both dissipative and eroded beaches） located in the Colombian Caribbean coast. Based on these measurements, we have carried out a spectral analysis in order to identify the frequency components that characterize the wave and its energy; thus, we identified the characteristic frequencies of iufragravity waves to finally filter the infragravity signal on each beach in different seasonal periods. Among the results of the Welch spectrum applied to surface elevation time series, we found that, the frequencies＇ energy of the sea-swell band decreases due to bottom friction and wave breaking as the wave approaches the shore, while the frequencies＇ energy of the infragravity band increases significantly. In addition, for the wavelet analysis, we could observe how the energy of the infragravity band, especially the lowest frequencies gain energy as the waves approaches the coast. Furthermore, based on the infragravity wave obtained from the extreme wave event registered during the field campaign we can conclude that the contribution of this signal is important in the erosion problems presented in the beaches of Galerazamba and Manzanillo del Mar. Finally, these results show the need to realize other studies that allow us to understand deeply, the role of infragravity waves on the morphological changes that occurs in these beaches.

关键词： infragravity waves long waves experimental analysis fourier analysis wavelet transform

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Self-deception can evolve under appropriate costs

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Current Zoology 2015年第2期61卷 382-396页

作者： juan camilo RAMiREZ James A. R. MARSHALL Department of Computer Science University of Sheffield Sheffield S 1 4DP United Kingdom

Apparent biases in decision making by animals, including humans, seem to present an evolutionary puzzle, since one would expect decisions based on biased （unrealistic） information to be suboptimal. Although cognitive biases are hard to diag- nose in real animals （Marshall et al., 2013b）, we investigate Trivers＇ proposal that individuals should self-deceive first in order to better deceive others （Trivers, 2011）. Although this proposal has been scrutinized extensively （Bandura et al., 2011） it has not been formally modelled. We present the first model designed to investigate Trivers＇ proposal. We introduce an extension to a re- cent model of the evolution of self-deception （Johnson and Fowler, 2011）. In the extended model individuals make decisions by taking directly into account the benefits and costs of each outcome and by choosing the course of action that can be estimated as the best with the information available. It is shown that in certain circumstances self-deceiving decision-makers are the most evolutionarily successful, even when there is no deception between these. In a further extension of this model individuals addi- tionally exhibit deception biases and Trivers＇ premise （that effective deception is less physiologically costly with the aid of self-deception） is incorporated. It is shown that under Trivers＇ hypothesis natural selection favors individuals that self-deceive as they deceive others .

关键词： Self-deception Deception Overconfidence Cognitive biases Optimal decision-making Optimal behavior

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Suspended sediment transport in the Magdalena River(Colombia,South America):Hydrologic regime,rating parameters and effective discharge variability

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International Journal of Sediment Research 2016年第01期31卷 25-35页

作者： Aldemar Higgins juan camilo Restrepo juan Carlos Ortiz Jorge Pierini Luis Otero (UNS-CIC-CCT)

The Magdalena River has the greatest length（1612 km）and drainage area（257400 km2）of any river system in Colombia,and its watershed occupies 24%of the Colombian *** river originates in the Andean Cordillera at an elevation of 3685 m and flows to its mouth in the Caribbean Sea（Bocas de Cenizas）.For this study,information on daily flow discharge（Q）,suspended sediment transport(Qsand mean suspended sediment concentration（Cs）from 1990-2010 for the Magdalena River,based on measurements at the Caiamar gauging station（the closest station to the mouth）,was provided by the Institute of Hydrology,Meteorology and Environmental Studies of Colombia（IDEAM in Spanish）.The mean annual suspended sediment load was 169±73×10～6tyr-1for the period from 1990-1999 and145±47×10～6 t yr1for the period from 2000-2010,amounting to a 14%reduction in the suspended sediment transport rate between the two *** sediment rating curve（Qs=aQb）was also evaluated for these two periods（1990-1999 and 2000-2010）.An analysis of the regression coefficients（a.b）for the two periods showed a decrease in b and an increase in a after 1999,which coincides with a decrease in suspended sediment *** change might be attributed to natural factors,including the accumulation of sediment in the Depresion Momposina and variation in hydro-climatological patterns in the Caribbean *** in effective transport were confirmed using three methods（Log-Normal and Normal distribution,and magnitude-frequency histogram）for the study period.

关键词： Suspended sediment transport Magdalena River Transport regime Effective discharge Sediment rating curve

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Analysis of the role of diffraction in topographic site effects using boundary element techniques

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Earthquake Science 2013年第5期26卷 341-350页

作者： juan Gomez Doriam Restrepo juan Jaramillo camilo Valencia Departamento de Ingeniería Civil Universidad EAFITMedellín Colombia

The role played by the diffraction field on the problem of seismic site effects is studied. For that purpose we solve and analyze simple scattering problems under P and SV in-plane wave assumptions, using two well known direct boundary-element-based numerical methods. After establishing the difference between scattered and diffracted motions, and introducing the concept of artificious and physically based incoming fields, we obtain the amplitude of the Fourier spectra for the diffracted part of the response： this is achieved after establishing the connection between the spatial distribution of the transfer function over the studied simple topographies and the diffracted field. From the numerical simulations it is observed that this diffracted part of the response is responsible for the amplification of the surface ground motions due to the geometric effect. Furthermore, it is also found that the diffraction field sets in a fingerprint of the topographic effect in the total ground motions. These conclusions are further supported by observations in the time-domain in terms of snapshots of the propagation patterns over the complete computational model. In this sense the geometric singularities are clearly identified as sources of diffraction and for the considered range of dimensionless frequencies it is evident that larger amplifications are obtained for the geometries containing a larger number of diffraction sources thus resulting in a stronger topographic effect. The need for closed-form solutions of canonical problems to construct a robust analysis method based on the diffraction field is identified.

关键词： Seismic site effects Topographiceffects Elastic wave scattering Diffractionof in-plane waves

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Efficacy and safety of XEN 45 gel stent alone or in combination with phacoemulsification in advanced open angle glaucoma patients: 1-year retrospective study

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International Journal of Ophthalmology(English edition) 2020年第8期13卷 1250-1256页

作者： Teresa Laborda-Guirao juan M Cubero-parra Antonio Hidalgo-Torres Department of Glaucoma Hospital La ArruzafaCordoba 14012Spain

AIM:To assess the effectiveness of the XEN 45 gel stent,either alone or combined with cataract surgery,in advanced stage open angle glaucoma(OAG)***:Retrospective and single-center study conducted on consecutive OAG patients who underwent a XEN 45 gel stent implantation surgery,between July 2017 and September *** primary efficacy end-point was the mean intraocular pressure(IOP)reduction at the end of the follow-up *** was defined as an IOP reduction of at least 20%and an IOP value≤18 mm Hg without(complete)or with(qualified)hypotensive ***:Seventy-four patients(80 eyes)were included in the *** the overall study sample,XEN implant significantly reduced IOP from 21.0(19.8 to 22.1)mm Hg at baseline to 9.3(8.2 to 10.4),10.7(9.6 to 11.9),13.4(12.2 to 14.7),14.5(13.6 to 15.4),14.7(13.8 to 15.6),and 14.7(13.9 to 15.4)mm Hg at 1 d,1 wk,1,3,6,and 12 mo of follow-up,respectively(P<0.0001 each).In the overall study population,at the end of the study the mean IOP reduction was 27.4%(23.3%to 31.5%).Adjusted IOP reduction was similar in XEN and XEN+phacoemulsification groups[30.0(23.4 to 36.4)mm Hg vs 24.8(18.4 to 31.2)mm Hg,respectively,P=0.2939].At the last follow-up visit,52(65.0%)eyes were considered success,29(36.3%)eyes as complete success and 23(28.7%)as qualified *** number of hypotensive medications was significantly reduced from 2.8(2.7 to 3.0)at baseline to 1.1(0.8 to 1.3),P<***-Meier survival analysis did not find any difference in the success rate between XEN and XEN+PHACO,mean hazard ratio 0.56,95%CI 0.26 to 1.23;P=*** was performed in 7(8.8%)eyes at months 1(n=3);3(n=2);4(n=1)and 11(n=1).Eleven(13.8%)eyes presented adverse ***:XEN implant,either alone or in combination with phacoemulsification,significantly reduced the IOP and the number of hypotensive medications in patients with OAG in advanced stage.

关键词： open angle glaucoma advanced stage XEN implant intraocular pressure minimally-invasive glaucoma surgery

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Geographic-Scale Coffee Cherry Counting with Smartphones and Deep Learning

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Plant Phenomics 2024年第2期6卷 390-400页

作者： juan camilo Rivera-Palacio Christian Bunn Eric Rahn Daisy Little-Savage Paul Günter Schmidt Masahiro Ryo Leibniz Centre for Agricultural Landscape Research(ZALF) Müncheberg15374Germany Alliance of Bioversity International and CIAT Rome00153Italy Brandenburg University of Technology Cottbus-Senftenberg Cottbus03046Germany Producers Direct LondonE28EXUK

Deep learning and computer vision,using remote sensing and drones,are 2 promising nondestructive methods for plant monitoring and ***,their applications are infeasible for many crop systems under tree canopies,such as coffee crops,making it challenging to perform plant monitoring and phenotyping at a large spatial scale at a low *** study aims to develop a geographic-scale monitoring method for coffee cherry counting,supported by an artificial intelligence(AI)-powered citizen science *** approach uses basic smartphones to take a few pictures of coffee trees;2,968 trees were investigated with 8,904 pictures in Junin and Piura(Peru),Cauca,and Quindio(Colombia)in 2022,with the help of nearly 1,000 smallholder coffee ***,we trained and validated YOLO(You Only Look Once)v8 for detecting cherries in the dataset in *** average number of cherries per picture was multiplied by the number of branches to estimate the total number of cherries per *** model's performance in Peru showed an R^(2)of *** the model was tested in Colombia,where different varieties are grown in different biogeoclimatic conditions,the model showed an R^(2)of *** overall performance in both countries reached an R^(2)of *** results suggest that the method can be applied to much broader scales and is transferable to other varieties,countries,and *** our knowledge,this is the first AI-powered method for counting coffee cherries and has the potential for a geographic-scale,multiyear,photo-based phenotypic monitoring for coffee crops in low-income countries worldwide.

关键词： geographic learning scale coffee deep with cherry counting smartphones

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Tuberculous pericarditis-a silent and challenging disease:A case report

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World Journal of Clinical Cases 2022年第6期10卷 1869-1875页

作者： Oscar David Lucero Marlon Mauricio Bustos Darwin Jhoan Ariza Rodriguez juan camilo Perez Department of Internal Medicine Hospital Universitario San IgnacioBogota 110231Colombia Internal Medicine Resident Pontificia Universidad JaverianaBogota 110231Colombia

BACKGROUND Tuberculous pericarditis(TP)remains a challenge for endemic *** developing countries,one to two percent of patients with pulmonary tuberculosis develops *** SUMMARY A 49-year-old woman presented with dyspnea,chest pain and dry *** physical examination,veiled heart sounds were *** electrocardiogram showed low-voltage complexes and the transthoracic echocardiography revealed a large and free-looking pericardial *** patient was taken for an open *** pericardial fluid revealed high levels of adenosine deaminase and Ziehl-Neelsen stain showed acid-fast *** chain reaction study for Mycobacterium tuberculosis in pericardial fluid was *** patient received tetra conjugate management with adequate clinical response after the first week of treatment and resolution of fever and chest *** In cases of TP,obtaining pericardial fluid and/or pericardial biopsy is the most efficient strategy to confirm the *** diagnosis of this entity will allow physicians to initiate timely treatment,avoid complications and improve the patient's clinical outcome,so we consider the description of this case pertinent and its review in the literature.

关键词： Tuberculosis Pericardial disease Tuberculous pericarditis Pericardial effusion Mycobacterium tuberculosis Case report

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Blood Flow Simulation in the Femoral Artery

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Journal of Electronic Science and Technology 2018年第3期16卷 269-279页

作者： camilo A.Naranjo Andrés F.Villa juan C.Vélez Ricardo A.Prato Alberto J.Cadena juan P.Tello IPATEC Institute CONICETBariloche R8400 Integra IT Bogotá 602 the Electronic and Electric Engineering Department Universidad del NorteBarranquilla 1569 the Institute of Mathematics Universidad de AntioquiaMedellin 050010 the Cardiology Department Clínica de la CostaBarranquilla 080020

This paper presents the development of the blood flow simulation in two dimensions over the real geometry of the femoral artery. The Navier-Stokes equations are solved using the finite element method, to obtain the distributions of the blood pressure and flow velocity in multiple instants of time and different places of the femoral artery and thus determine the current condition of the blood vessels. The velocity field shows a laminar behavior,where, the velocity is higher in the center of the artery and decreases as the blood flow approaches artery walls. In spite of all artery and blood flow properties not being considered, the values of pressure and velocity obtained are within the normal ranges. Finally the model is used to verify if there exist irregularities in the blood flow in both healthy subjects and sick patients.

关键词： Blood flow femoral artery finite elements Navier-Stokes pressure velocity

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