检索结果-南通市图书馆

maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

引用

Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan Huang Yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang ju.Yun ma Peng-Peng Li Hai-Wei Pu Xin-Yian Guo Jian-Gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion inju.y chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

De novo synthesis of atropisomeric benzofurans via Cu/SPDO complex catalyzed asymmetric formal [3 + 2] annulation

引用

Science China Chemistry 2025年第1期 174-180页

作者： Fan-Xiao Meng Xing-Yu Wang Ka Lu ju.Song Yang Fu-Min Zhang Ai-ju. ma Bao Du Yong-Qiang Tu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Lanzhou University School of Chemistry and Chemical Engineering Shanghai Jiao Tong University School of Biotechnology and Health Sciences Wuyi University

Herein, the de novo synthesis of atropisomeric benzofurans through the Cu/spirocyclic-pyrrolidine-oxazoline(SPDO) complex catalyze asymmetric formal [3 + 2] cycloaddition between quinones and ynamides is explored, producing a range of structurally diverse axially chiral benzofurans in satisfactory yields with good to excellent enantioselectivities. Furthermore, density functional theory calculations were applied to explain the possible reaction mechanism.

关键词：

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

State-of-the-art of 3D printing technology of cementitious material—An emerging technique for construction

引用

Science China(Technological Sciences) 2018年第4期61卷 475-495页

作者： ma GuoWei WANG Li ju.Yang College of Architecture and Civil Engineering Beijing University of Technology School of Civil Environmental and Mining Engineering The University of Western Australia School of Mechanics and Civil Engineering China University of Mining & Technology at Beijing State Key Laboratory of Coal Resources and Safe Mining China University of Mining & Technology at Beijing

In recent few years, significant improvement has been made in developing largescale 3 D printer to accommodate the need of industrial-scale 3 D printing. Cementitious materials that are compatible with 3 D printing promote rapid application of this innovative technique in the construction field with advantages of cost effective, high efficiency, design flexibility and environmental friendly. This paper firstly reviews existing 3 D printing techniques that are currently being used in commercial3 D printers. It then summarizes three latest development of largescale 3 D printing systems and identifies their relationships and limiting factors. Thereafter, critical factors that are used to evaluate the workability and printable performance of cementitious materials are specified. Easy-extrusive, easy-flowing, well-buildable, and proper setting time are significant for cementitious material to meet the critical requirements of a freeform construction process. Finally, main advantages, potential applications and the prospects of future research of 3 D printing in construction technology are suggested. The objective of this work is to review current design methodologies and operational constraints of largescale 3 D printing system and provide references for optimizing the performance of cementitious material and promote its responsible use with largescale 3 D printing technology.

关键词： 3D printing cementitious material construction automation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Study on concentration and turbulence of solid-liquid FAE in dispersal process

引用

Defence Technology（防务技术） 2018年第6期14卷 657-660页

作者： Jia-chen Chen Xin ma Qiu-ju.ma China Zhongyuan Engineering Corporation Beijing 100191China China Ordnance Society Beijing 100089China College of Resources&Safety Engineering China University of Mining&Technology(Beijing)Beijing 100083China

This paper describes numerical simulation on dispersion of the solid-liquid mixed fuel driven by explosion load. A model used in numerical calculation for dispersion of solid-liquid mixed fuel was established in this study. The concentration and turbulent intensity in the multiphase cloud of the solidliquid mixed fuel were obtained by numerical simulation. It was found that the fuel concentration tended to be 0.15 kg/m^3, the turbulence intensity tended to be 7 in 90 ms. The numerical results agree with those measured in the experiment.

关键词： Solid-liquid mixed fuel Concentration Turbulence intensity Numerical simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Minor and Minimum Cycle Bases of a 3-connected Planar Graph

引用

Acta mathematica Sinica,English Series 2009年第4期25卷 649-656页

作者： Deng ju.ma Han REN Department of mathematics East China Normal University Shanghai 200241 P.R. China School of Science Nantong University Jiangsu Province Nantong 226007 P. R. China Department of mathematics East China Normal University Shanghai 200241 P. R. China

In this paper, we prove that if any set of ｜E（G）｜- ｜V（G）｜＋ 1 facial cycles of a 3-connected planar graph G embedded in the plane doesn＇t form a minimum cycle base of G, then any minimum cycle base of G contains a separating cycle, and G has a minor isomorphic to T6, where T6 is the graph obtained from the complete graph K6 by deleting a path with four edges.

关键词： cycle space minimum cycle base 3-connected planar graph

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Superfluid Fermi Gases in a Rotating Anharmonic Trap

引用

Communications in Theoretical Physics 2011年第3期55卷 434-440页

作者： ma ju.n XUE ju.Kui College of Physics and Electronics Engineering Northwest Normal University Lanzhou 730070 China

The quadrupole mode frequency, the monopole mode frequency, and the critical rotational frequency for stirring a single vortex nucleation along the BEC-BCS crossover are obtained. The results show that, in a rotating anisotropic anharmonic trap, the quadrupole mode frequency and the critical rotational frequency for stirring a single vortex nucleation are modified significantly when the system crosses from the BEC side to the BCS side： the anisotropy of the trap induces a downshiff of the quadrupole mode frequency and the critical rotational frequency and helps the vortex formation in the system, while an anharmonic trap induces an upshift of the quadrupole mode frequency and the critical rotational frequency and suppresses the vortex formation in the system.

关键词： superfluid Fermi gases anisotropic anharmonic trap vortex

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Nonorientable Genus of the Join of Two Cycles

引用

Acta mathematica Sinica,English Series 2013年第12期29卷 2305-2320页

作者： Deng ju.ma Han REN School of Sciences Nantong University Department of mathematics East China Normal University

In this paper, we show that the nonorientable genus of Cm ＋ Cn, the join of two cycles Cm and Cn, is equal to [（（m-2）（n-2））/2] if m = 3, n ≡ 1 （mod 2）, or m ≥ 4, n ≥ 4, （m, n）（4, 4）. We determine that the nonorientable genus of C4 ＋C4 is 3, and that the nonorientable genus of C3 ＋Cn is n/2 if n ≡ 0 （mod 2）. Our results show that a minimum nonorientable genus embedding of the complete bipartite graph Km,n cannot be extended to an embedding of the join of two cycles without increasing the genus of the surface.

关键词： Surface nonorientable genus of a graph the join of two graphs

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Quantitative Investigation of Tomographic Effects in Abnormal Regions of Complex Structures

引用

Engineering 2021年第7期7卷 1011-1022页

作者： Longju. Dong Xiaojie Tong ju.ma School of Resources and Safety Engineering Central South UniversityChangsha 410083China

The detection of abnormal regions in complex structures is one of the most challenging targets for underground space *** or artificial geologic variations reduce the effectiveness of conventional exploration *** the emergence of real-time monitoring,seismic wave velocity tomography allows the detection and imaging of abnormal regions to be accurate,intuitive,and *** tomographic results are affected by multiple factors in practical small-scale applications,it is necessary to quantitatively investigate those *** adopted an improved three-dimensional(3D)tomography method combining passive acoustic emission acquisition and active ultrasonic *** varying individual parameters(i.e.,prior model,sensor configuration,ray coverage,event distributions,and event location errors),37 comparative tests were *** quantitative impact of different factors was *** experiments showed that the method could effectively adapt to complex *** optimal input parameters based on quantization results can significantly improve the detection reliability in abnormal regions.

关键词： Detection of abnormal regions Tomographic effects Wave velocity Ray path

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Target localization method of non-cooperative spacecraft on on-orbit service

引用

Chinese Journal of Aeronautics 2022年第11期35卷 336-348页

作者： Yingxiao LI ju.HUO Ping ma Ruiye JIANG Control and Simulation Center Harbin Institute of TechnologyHarbin 150001 China

With the explosion of the number of meteoroid/orbital debris in terrestrial space in recent years, the detection environment of spacecraft becomes more complex. This phenomenon causes most current detection methods based on machine learning intractable to break through the two difficulties of solving scale transformation problem of the targets in image and accelerating detection rate of high-resolution images. To overcome the two challenges, we propose a novel noncooperative target detection method using the framework of deep convolutional neural ***, a specific spacecraft simulation dataset using over one thousand images to train and test our detection model is built. The deep separable convolution structure is applied and combined with the residual network module to improve the network’s backbone. To count the different shapes of the spacecrafts in the dataset, a particular prior-box generation method based on K-means cluster algorithm is designed for each detection head with different scales. Finally, a comprehensive loss function is presented considering category confidence, box parameters, as well as box confidence. The experimental results verify that the proposed method has strong robustness against varying degrees of luminance change, and can suppress the interference caused by Gaussian noise and background complexity. The mean accuracy precision of our proposed method reaches 93.28%, and the global loss value is 13.252. The comparative experiment results show that under the same epoch and batchsize, the speed of our method is compressed by about 20% in comparison of YOLOv3, the detection accuracy is increased by about 12%, and the size of the model is reduced by nearly 50%.

关键词： Spacecraft service High resolution image Object detection Complex environment Lightweight model

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Energy Spectrum of La3Lu2Ga3O12：Cr^3＋ and Its Pressure-Induced R-Line-Shift Reversal

引用

Communications in Theoretical Physics 2005年第6X期44卷 1103-1114页

作者： ma Dong-Ping CHEN ju.Rong Department of Applied Physics Sichuan University Chengdu 610065 Chinat International Centre for materials Physics the Chinese Academy of Sciences Shenyang 110015 China

By means of both the theory for pressure-induced Shifts （PS） of energy spectra and the theory for shifts of energy spectra due to electron-phonon interaction （EPI）, the normal-pressure energy spectra of α and β centers of Cr^3＋ ions for LLGG：Cr^3＋ and the PS＇s of R1 lines and U band of these centers have been calculated at 10 K, respectively. The total calculated results are in very good agreement with the experimental data. For LLGG：Cr^3＋, the pressureinduced low-high crystal-field transition and the reversal of R1-line PS take place. The pressure-dependent variation of Rmix^ei （2E - 4T2） [mixing-degree of （t2^2 （^3T1）e^4T2） and （t2^3 E） base-wavefunctions in the wavefunction of R1 state without EPI] plays a key role for the reversal of R1-line PS. The behavior of the pure electronic PS of R1 line is quite different from that of the PS of R1 line due to EPI. It is the combined effect of them that gives rise to the total PS of R1 line. The comparison between R1-line PS＇s of GSGG：Cr^3＋ and LLGG：Cr^3＋ has been made. It is found that a peak of R1-line PS appears at Rmix^ei （^2E - ^4T2） ≈ 0.08.

关键词： pressure-induced reversal of Rl-line shift low high crystal-field transition electron-phonon interaction mixing of base-wavefunctions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：