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Chinese Journal of Traumatology 2016年第6期19卷 371-372页

作者： Hu-Sai ma ju-hua ma Feng-Lai Xue Xiang-Ning Fu Ni Zhang Department of Thoracic Surgery Qinghai Provincial People's Hospital Xining 810007 Qinghai Province China Department of Thoracic Surgery Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China

From January 2013 to January 2015, 19 patients of traumatic hemothorax with hemorrhagic shock were treated in our department by thoracoscopic surgery combined with autologous blood transfusion. This study retrospectively analyzed the therapeutic effect and shared our experience. The average amount of blood transfused back was 662.41 ml ± 269.15 ml. None of the patients developed transfusion reaction and were all discharged uneventfully. Thoracoscopic surgery combined with autologous blood transfusion is effective in the rescue of patients with progressive hemothorax and hemorrhagic shock. When corresponding indications are well managed, treatment for these patients is quicker, safer, and more effective.

关键词： Thoracoscopic surgeryAutologous blood transfusionTraumatic hemothoraxHemorrhagic shock

Local magnetic moment oscillation around an Anderson impurity on graphene

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 192-201页

作者： Shuai Li Zhen ma Jin-hua Gao School of Science Hebei University of Science and Technology School of Electronics and Information Zhengzhou University of Light Industry School of Physics and Wuhan National High magnetic Field Center Huazhong University of Science and Technology

We theoretically investigate the spin resolved Friedel oscillation （FO） and quasiparticle interference （QPI） in graphene induced by an Anderson *** the impurity becomes magnetic,the resulted FO becomes spin dependent,which gives rise to a local magnetic moment oscillation with an envelop decaying as r-2in real space in the doping ***,at half filling,the electron density and local magnetic moment will not oscillate but decay as *** spin resolved FO has both sublattice and spin ***,the local magnetic moment decay at half filling only occurs at one sublattice of graphene,which is quite like the phenomenon observed in the STM experiment (***ález-Herrero et al.,Science 352,437 （2016）).We further give an analytic formula about such spin dependent FO based on the stationary phase ***,we study the interference of quasiparticles around the magnetic impurity by calculating the spin dependent Fourier-transformed local density of states （FT-LDOS）.Our work gives a comprehensive understanding about the local magnetic moment oscillation around an Anderson impurity on graphene.

关键词： Friedel oscillation local magnetic moment graphene Anderson impurity

maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan huang Yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang ju-Yun ma Peng-Peng Li Hai-Wei Pu Xin-Yian Guo Jian-Gang Shen Su-hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury

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Neural Regeneration Research 2025年第2期20卷 587-597页

作者： Tong Li Hui-Min Xing Hai-Dong Qian Qiao Gao Sheng-Lan Xu hua ma Zai-Long Chi State Key Laboratory of Ophthalmology Optometry and Visual ScienceEye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina

Several studies have found that transplantation of neural progenitor cells(NPCs)promotes the survival of injured ***,a poor integration rate and high risk of tumorigenicity after cell transplantation limits their clinical *** extracellular vesicles(sEVs)contain bioactive molecules for neuronal protection and *** studies have shown that stem/progenitor cell-derived sEVs can promote neuronal survival and recovery of neurological function in neurodegenerative eye diseases and other eye *** this study,we intravitreally transplanted sEVs derived from human induced pluripotent stem cells(hiPSCs)and hiPSCs-differentiated NPCs(hiPSC-NPC)in a mouse model of optic nerve *** results show that these intravitreally injected sEVs were ingested by retinal cells,especially those localized in the ganglion cell *** with hiPSC-NPC-derived sEVs mitigated optic nerve crush-induced retinal ganglion cell degeneration,and regulated the retinal microenvironment by inhibiting excessive activation of *** analysis further revealed that hiPSC-NPC derived sEVs transported neuroprotective and anti-inflammatory miRNA cargos to target cells,which had protective effects on RGCs after optic nerve *** findings suggest that sEVs derived from hiPSC-NPC are a promising cell-free therapeutic strategy for optic neuropathy.

关键词： exosome miRNA neural progenitor cell neurodegeneration neuroinflammation neuroprotection optic nerve crush optic neuropathy retinal ganglion cell small extracellular vesicles

Expression of Notch signaling in transitional cell carcinoma of bladder and its clinical implication

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Expression of Notch signaling in transitional cell carcinoma...

Study on the expressions of MMP-2,MMP-9 and TIMP-3 in human transitional cell carcinoma of bladder and discuss their clinical significance

第十三届全国泌尿外科学术会议暨第八届全球华人泌尿外科学术会议

作者： Shi Tao-Ping, Zhu Hong-Gang, Chen jun, Zhang jun, Lang Bin, Fu Bin, Xu Kai,Wu Zhen-Qi, Ai Xing, Hu Jian-Ting, Wang Bao-jun, ju Zheng-hua, ma Xin, Li Hong-Zhao, Zheng Tao and Zhang Xu* From the Department of Urology, Tongji Hospital, Tongji Medical College, huazhong University of Science and Technology, Wuhan 430030, People’s Republic of China

Objective To study the expression of Notch receptors and ligands in transitional cell carcinoma of bladder, and to investigate its clinical and pathological implications. Methods We detected the expression of Notch-1,... 详细信息

关键词： Bladder neoplasms Transitional cell carcinoma Immunohistochemistry Notch-1 Jagged-1 Delta-like-1

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Study on the expressions of MMP-2,MMP-9 and TIMP-3 in human ...

Microstructure and mechanical property of Mg-10Gd-2Y-1.5Zn-0.5Zr alloy processed by eight-pass equal-channel angular pressing

第十三届全国泌尿外科学术会议暨第八届全球华人泌尿外科学术会议

作者： Zhu Hong-Gang, Shi Tao-Ping, Chen jun, Zhang jun, Lang Bin, Fu Bin, Xu Kai, Wu Zhen-Qi, Ai Xing, Hu Jian-Ting, Wang Bao-jun, ju Zheng-hua, ma Xin, Li Hong-Zhao, Zheng Tao and Zhang Xu Department of Urology, Tongji Hospital, Tongji Medical College, huazhong University of Science and Technology, Wuhan 430030, People’s Republic of China

Objective To investigate the expressions of MMP-2, MMP-9 and TIMP-3 in human transitional cell carcinoma of bladder and discuss their clinical significance. Methods Using a method of immunohistochemical stains and a HMIAS-2000 analysis system, the expressions of MMP-2, MMP-9 and TIMP-3 were analyzed in human samples from 35 cases of bladder carcinoma (tumor group), 10 cases of

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Rare Metals 2023年第4期42卷 1371-1377页

作者： huan Liu Jia ju Xiao-Wei Yang Yu-hua Li Jing-hua Jiang Ai-Bin ma College of Mechanics and materials Hohai UniversityNanjing211100China Suqian Research Institute of Hohai University Suqian223800China College of materials Engineering Nanjing Institute of TechnologyNanjing211167China

In this work,a high-strength Mg-10Gd-2Y-1.5Zn-0.5Zr(wt%)alloy was prepared via eight passes of equal-channel angular pressing(ECAP).The microstructures and mechanical properties of as-cast and ECAP alloys were systematically investigated by X-ray diffraction(XRD),optical microscopy(OM),scanning electron microscopy(SEM),transmission electron microscopy(TEM)and electronic universal testing *** obtained results indicate that the microstructure of as-cast alloy consists ofα-Mg dendrite,network Mg3(Gd,Y,Zn)phase and lamellar 14H long-period stacking ordered(LPSO)phase which is precipitated near the boundary of Mg3(Gd,Y,Zn)*** eight-pass ECAP,the network Mg3(Gd,Y,Zn)phase is deformed and ***,the refined Mg_3(Gd,Y,Zn)particles are not distributed uniformly in the matrix,but still aggregated at the interdendritic ***,the content of 14H lamellas increases obviously,and they become bent and kinked during severe *** is activated in the region between Mg3(Gd,Y,Zn)particles and 14H *** test at room temperature indicates that the ECAP alloy exhibits excellent mechanical property with compressive strength of 518 MPa and fracture strain of 21.6%.The comprehensive high strength and toughness could be ascribed to the refined Mg_3(Gd,Y,Zn)particles,DRX grains and kinked 14H LPSO phase.

关键词： Mg-Gd-Y-Zn-Zr Long-period stacking ordered phase Equal-channel angular pressing Compression strength Fracture strain

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低氧暴露后大鼠外周血及骨髓红系的变化

中国组织工程研究 2025年第25期29卷 5390-5395页

作者：熊华李金杰王璐马婕青海大学附属医院(临床医学院) 青海省西宁市810001

背景:低氧暴露下大鼠外周血红细胞变化与骨髓有核红细胞增殖变化相关。低氧诱导因子、促红细胞生成素等相关调控因素参与其中。目的:探讨大鼠低氧暴露后外周血红细胞及骨髓有核红细胞的变化特点及相关因素。方法:模拟海拔5000 m的低压... 详细信息

背景:低氧暴露下大鼠外周血红细胞变化与骨髓有核红细胞增殖变化相关。低氧诱导因子、促红细胞生成素等相关调控因素参与其中。目的:探讨大鼠低氧暴露后外周血红细胞及骨髓有核红细胞的变化特点及相关因素。方法:模拟海拔5000 m的低压低氧环境建立实验大鼠模型,对照组大鼠饲养在海拔2260 m的实验室内,对比低氧暴露前后大鼠血常规、骨髓有核红细胞比例及低氧诱导因子、促红细胞生成素等相关指标。结果与结论:①实验组大鼠外周血红细胞计数、血红蛋白、红细胞压积等指标较对照组升高(P<0.05);②实验组大鼠骨髓CD71^(+)有核红细胞比例较对照组升高(P<0.05);③实验组大鼠骨髓CD71^(+)有核红细胞中低氧诱导因子2α表达水平较对照组升高(P<0.05);④实验组大鼠骨髓上清液促红细胞生成素水平较对照组升高(P<0.05)。结果表明,低氧暴露后大鼠外周血红细胞及骨髓有核红细胞比例增高,可能与骨髓有核红细胞中低氧诱导因子2α及骨髓上清液中促红细胞生成素水平增高有关。

关键词：低氧大鼠外周血红细胞骨髓有核红细胞

Abnormal nonlinear optical responses on the surface of topological materials

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npj Computational materials 2022年第1期8卷 1045-1052页

作者： Haowei Xu hua Wang ju Li Department of Nuclear Science and Engineering Massachusetts Institute of TechnologyCambridgeMA02139USA Department of materials Science and Engineering Massachusetts Institute of TechnologyCambridgeMA02139USA

The nonlinear optical(NLO)responses of topological materials are under active *** previous works studied the surface and bulk NLO responses *** we develop a generic Green’s function framework to investigate the surface and bulk NLO responses *** reveal that the topological surface can behave disparately from the bulk under light ***,the photocurrents on the surface can flow in opposite directions to those in the bulk interior,and the light-induced spin current on the surface can be orders of magnitude stronger than its bulk counterpart on a per-volume *** also study the responses under inhomogeneous field and higher-order NLO effect,which are all distinct on the *** anomalous surface responses suggest that light can be a valuable tool for probing the surface states of topological ***,the surface effects should be prudently considered when investigating the optical properties of topological materials.

关键词： materials. surface. topological

Recommend trustworthy services using interval numbers of four parameters via cloud model for potential users

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Frontiers of Computer Science 2015年第6期9卷 887-903页

作者： hua ma Zhigang HU School of Software Central South University Changsha 410075 China School of Information Science and Engineering Hunan International Economics University Changsha 410205 China

How to discover the trustworthy services is a challenge for potential users because of the deficiency of us- age experiences and the information overload of QoE （qual- ity of experience） evaluations from consumers. Aiming to the limitations of traditional interval numbers in measuring the trustworthiness of service, this paper proposed a novel ser- vice recommendation approach using the interval numbers of four parameters （INF） for potential users. In this approach, a trustworthiness cloud model was established to identify the eigenvalue of INF via backward cloud generator, and a new formula of INF possibility degree based on geometrical anal- ysis was presented to ensure the high calculation precision. In order to select the highly valuable QoE evaluations, the similarity of client-side feature between potential user and consumers was calculated, and the multi-attributes trustwor- thiness values were aggregated into INF by the fuzzy ana- lytic hierarchy process method. On the basis of ranking INF, the sort values of trustworthiness of candidate services were obtained, and the trustworthy services were chosen to recommend to potential user. The experiments based on a real-world dataset showed that it can improve the recommendation accuracy of trustworthy services compared to other approaches, which contributes to solving cold start and information overload problem in service recommendation.

关键词： service recommendation trustworthiness interval numbers of four parameters cloud model potential users