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Asian Pacific Journal of Tropical Biomedicine 2015年第12期5卷 996-1004页

作者： De-Hu Chen Rui-Qi Lu Xiao-Chun Ni ju-gang wu Shou-Lian Wang Bo-Jian Jiang Ji-Wei Yu Department of General Surgery Third People's Hospital Shanghai Jiao Tong University School of Medicine

Objective:To investigate the influence of CD133+expression on patients'survival and resistance of CD133+cells to anti-tumor agents in gastric cancer(GC).Methods:Influence of CD133 expression on prognosis was analyzed employing samples from patients with *** cell lines were utilized to separate CD133+and CD133-subpopulations by immunomagnetic separation and to analyze the biological features of two subpopulations in vitro and in vivo,especially in resistant to anti-tumor reagents and its apoptotic ***:The lower CD133+group showed a significantly better survival compared with the higher CD133+*** highest content of CD133+subpopulations for KATO-III cells had stronger proliferative ability than CD133-subpopulations.A single CD133+cell was capable of generating new cell colony and the tumorigenicity rate in nude mice was100%for CD133+clonal spheres or for CD133+cells,but 0%for ***,the higher expression levels of Oct-4,Sox-2,Musashi-1 and ABCG2 in CD133+clonal spheres were identified compared with CD133+cells or *** the treatment of anti-tumor reagents,CD133+cells had lower suppression rates compared with CD133-cells while lower level of Bcl-2 and higher level of Bax were found in CD133+cells compared with ***:The patients with lower CD133+expression had a better *** CD133+cells in clonal sphere shared the ability to be self-renewable,proliferative,tumorigenic and resistant to anti-tumor agents as probably regulated by Bcl-2 and Bax.

关键词： Stomach Cancer CD133 Tumor initiating cells

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan Huang Yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang ju-Yun Ma Peng-Peng Li Hai-Wei Pu Xin-Yian Guo Jian-gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

Leader-follower: Human-centered intention-guided controller for novel SuperLimb with application to load-carrying scenarios

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Science China Technological Sciences 2025年第1期 325-338页

作者： Qinghua ZHANG Xianglong LI Hongwei JING Kerui SUN Yuancheng LI Sikai ZHAO Lele LI Haotian ju Ziqi WANG Rui wu Tianjiao ZHENG Jie ZHAO Yanhe ZHU The State Key Laboratory of Robotics and System Harbin Institute of Technology The Learning Algorithms and Systems Laboratory School of Engineeringécole Polytechnique Fédérale de Lausanne

Supernumerary robotic arms(SuperLimb) are a new type of wearable robot that works closely with humans as a third hand to augment human operation capability. Accurate conveyance of wearers' intentions, allocation of roles, and humancentered interaction considerations are the key points in the process of human–SuperLimb collaboration. This paper proposes a human-centered intention-guided leader–follower controller that relies on the dynamic modeling of SuperLimb with application to load-carrying scenarios. The proposed leader–follower controller takes the human as the leader and the SuperLimb as the follower, achieving effective information communication, autonomous coordination, and good force compliance between SuperLimb, humans, and the environment under human safety assurance. First, the human–SuperLimb dynamic system is modeled to achieve force interaction with the environment and wearer. Second, to achieve the precise intention extraction of humans, pose data from five visual odometry sensors are fused to capture the human state, the generalized position, the velocity of hands, and the surface electromyography signals from two myoelectric bracelets sensors are processed to recognize the natural hand gestures during load-carrying scenarios by a designed Swin transformer network. Then, based on the real-time distance detection between human and mechanical limbs, the security assurance and force-compliant interaction of the human–SuperLimb system are realized. Finally, the human hand muscle intention recognition, human–robot safety strategy verification,and comparative load-carrying experiments with and without the proposed method are conducted on the SuperLimb *** showed that the task parameters are well estimated to produce more reasonable planning trajectories, and SuperLimb could well understand the wearer's intentions to switch different SuperLimb actions. The proposed sensor-based human–robot communication framework motivates future studies of o

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人口流动对我国高等教育资源配置的影响及对策研究

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黑龙江高教研究 2025年第1期43卷 31-37页

作者：陈茂建吴刚龙福建教育学院福建福州350001 黎明职业大学福建泉州362000

基于2013一2022年31个省份面板数据,使用固定效应模型实证检验人口流动对我国高等教育资源配置的影响。结果发现:第一,人口流动对高等教育资源配置具有显著影响作用,人口净流入地区和净流出地区分别对高等教育资源配置产生负向影响和正... 详细信息

基于2013一2022年31个省份面板数据,使用固定效应模型实证检验人口流动对我国高等教育资源配置的影响。结果发现:第一,人口流动对高等教育资源配置具有显著影响作用,人口净流入地区和净流出地区分别对高等教育资源配置产生负向影响和正向影响;第二,人口流动对高等教育资源配置的影响因地区经济发展水平、城镇化水平以及人口结构的不同而存在差异,东部地区、城镇化水平为中等的地区、中等文化水平程度在人口流动对高等教育资源配置的影响方面均最显著。基于研究结果一,提出以下对策:一是加强人口流入地区的高等教育资源配置;二是优化人口流出地区的高等教育资源配置。基于研究结果二,提出以下对策:一是加强东部地区的高等教育资源配置;二是注重城镇化水平中等地区的高等教育资源配置;三是加强教育普及程度相对均衡地区的高等教育资源配置。

关键词：人口流动高等教育资源配置对策

Current challenge and perspective of PGM-free cathode catalysts for PEM fuel cells

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Frontiers in Energy 2017年第3期11卷 286-298页

作者： gang wu Department of Chemical and Biological Engineering University at Buffalo The State University of New York Buffalo New York 14260 USA

To significantly reduce the cost of proton exchange membrane fuel cells, platinum-group metal （PGM）-free cathode catalysts are highly desirable. Current M-N-C （M： Fe, Co or Mn） catalysts are considered the most promising due to their encouraging performance. The challenge thus has been their stability under acidic conditions, which has hindered their use for any practical applications. In this review, based on the author＇s research experience in the field for more than 10 years, current challenges and possible solutions to overcome these problems were discussed. The current Edisonian approach （i.e., trial and error） to developing PGM-free catalysts has been ineffective in achieving revolutionary breakthroughs. Novel synthesis techniques based on a more methodolo- gical approach will enable atomic control and allow us to achieve optimal electronic and geometric structures for active sites uniformly dispersed within the 3D architec- tures. Structural and chemical controlled precursors such as metal-organic frameworks are highly desirable for making catalysts with an increased density of active sites and strengthening local bonding structures among N, C and metals. Advanced electrochemical and physical characterization, such as electron microscopy and X-ray absorption spectroscopy should be combined with first principle density functional theory （DFT） calculations to fully elucidate the active site structures.

关键词： oxygen reduction fuel cells cathode non- precious metal catalysts carbon nanocomposites

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圈层化网络社群对青少年的伦理挑战及其应对

教学与管理 2025年第1期 34-38页

作者：刘昊琛冯永刚山东师范大学教育学部济南250014

青少年在网络空间构筑了基于共同兴趣和偏好的“新社群”。网络社群内部的圈层化趋势加强了青少年之间的联系与共鸣,在一定程度上重塑了他们的社会认知和伦理判断。然而,这种圈层化也带来了新型场域对伦理空间的冲击、圈层区隔对伦理关... 详细信息

青少年在网络空间构筑了基于共同兴趣和偏好的“新社群”。网络社群内部的圈层化趋势加强了青少年之间的联系与共鸣,在一定程度上重塑了他们的社会认知和伦理判断。然而,这种圈层化也带来了新型场域对伦理空间的冲击、圈层区隔对伦理关系的界分、特定惯习对伦理实践的影响和微观规训对伦理意识的裹挟等问题,将他们置于伦理挑战的情境中进行考量。鉴于此,创构主流舆论传播新格局、释放网络圈层整合共振力、激活多元话语互促生命力、注重外部治理和内部自律的统一性,对于网络社会治理和构建网络空间命运共同体具有重要意义。

关键词：圈层化网络社群青少年伦理挑战

屈原《离骚》在英语世界的译介特征与传播影响

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三峡大学学报（人文社会科学版） 2025年第1期47卷 24-28页

作者：伍钢北京外国语大学英语学院北京100089 三峡大学外国语学院湖北宜昌443002

屈原《离骚》是我国古代乃至世界诗歌史上最伟大的诗篇之一。自《离骚》1879年首次被汉学家帕克尔(庄延龄)翻译成英语以来,先后有近20位中外学者参与和从事了《离骚》的英译,因此《离骚》也形成了不少风格各异的英语译本。本文采用历时... 详细信息

屈原《离骚》是我国古代乃至世界诗歌史上最伟大的诗篇之一。自《离骚》1879年首次被汉学家帕克尔(庄延龄)翻译成英语以来,先后有近20位中外学者参与和从事了《离骚》的英译,因此《离骚》也形成了不少风格各异的英语译本。本文采用历时分析法对屈原《离骚》在英语世界的译介特征和传播影响展开梳理和总结,发现《离骚》目前在英语世界的译介特征具备以下特点:译者身份呈现多重性、译者风格呈现多元化、译介模式呈现复合性。其传播影响具备以下特点:传播媒介呈现多样性、译本影响呈现深远性。

关键词：屈原离骚英语世界译介特征传播影响

Comprehensive comparison of small-scale natural gas liquefaction processes using brazed plate heat exchangers

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Frontiers in Energy 2020年第4期14卷 683-698页

作者： Jitan wu Yonglin ju Institute of Refrigeration and Cryogenics Shanghai Jiao Tong UniversityShanghai 200240China

The brazed plate heat exchanger(BPHE)has some advantages over the plate-fin heat exchanger(PFHE)when used in natural gas liquefaction processes,such as the convenient installation and transportation,as well as the high tolerance of carbon dioxide(CO2)***,the BPHEs with only two channels cannot be applied directly in the conventional liquefaction processes which are designed for multi-stream heat ***,the liquefaction processes using BPHEs are different from the conventional PFHE *** this paper,four different liquefaction processes using BPHEs are optimized and comprehensively compared under respective optimal *** processes are compared with respect to energy consumption,economic performance,and *** genetic algorithm(GA)is applied as the optimization method and the total revenue requirement(TRR)method is adopted in the economic *** results show that the modified single mixed refrigerant(MSMR)process with part of the refrigerant flowing back to the compressor at low temperatures has the lowest specific energy consumption but the worst robustness of the four *** MSMR with fully utilization of cold capacity of the refrigerant shows a satisfying robustness and the best economic *** research in this paper is helpful for the application of BPHEs in natural gas liquefaction processes.

关键词： liquefied natural gas brazed plate heat exchanger energy consumption economic performance robustness

Characteristics of carbonatites from the northern part of the Korean Peninsula: A perspective from distribution, geology and geochemistry

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Geoscience Frontiers 2021年第1期12卷 173-181页

作者： Jinkon ju Yunsong Kim Mansik gang School of Resource and Exploration Engineering Kim Chaek University of TechnologyPyongyangNorth Korea Central Survey Group of Mineral Resources PyongsongNorth Korea

The present study introduces the carbonatite in the northern part of the Korean Peninsula for the first *** exploration and development of the phosphorus-bearing carbonate rocks in the area have accumulated new geological data which gave us an opportunity to study origin of the carbonate *** conducted geological survey,geochemical analyses of trace elements and rare earth elements,and carbon and oxygen isotope analyses for the carbonatites from Ssangryong,Pungnyon,Yongyu and Puhung districts of the northern part of the Korean *** research confirms that the phosphorus-bearing carbonate rocks are carbonatite originating from the *** studied carbonatites are distributed at the junctions of ring and linear structures or around their margins and contain a greater amount of REEs,Y,and Sr than carbonate *** carbonatites in Yongyu and Puhung area show evidence that they were formed from mantle plume generated at the lower mantle and display similar fractionation characteristics to carbonatites in Barrado Itapirapua in Brazil and Kalkfeld and Ondurakorume in *** patterns of the carbonatites are typical of carbonatites and the carbon and oxygen isotope analyses demonstrate that the carbonatites were originated from *** carbonatites from the northern part of the Korean Peninsula have a great potential for sources of REE,Y,PGE(platinum group elements),copper,and gold.

关键词： Carbonatite Rare-earth elements Stable isotope composition Phoscorite Platinum group elements Korean Peninsula

Anisotropy in tensile properties and fracture behaviour of 316L stainless steel parts manufactured by fused deposition modelling and sintering

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Advances in Manufacturing 2022年第3期10卷 345-355页

作者： Lin-ju Wen Xiao-gang Hu Zhong Li Zhan-Hua Wang Ji-Kai wu Qiang Zhu Department of Mechanical and Energy Engineering Southern University of Science and TechnologyShenzhen 518055GuangdongPeople's Republic of China Department of Mechanical Engineering Polytechnic University of Milan20156 MilanItaly SUSTechAcademy for Advanced Interdisciplinary Studies Shenzhen 518055GuangdongPeople's Republic of China Shenzhen Key Laboratory for Additive Manufacturing of High-performance Materials Shenzhen 518055GuangdongPeople's Republic of China Elementplus Material Technology Co.Ltd. Shenzhen 518055GuangdongPeople's Republic of China

Fused deposition modelling and sintering(FDMS)is a potential metal additive manufacturing technology due to its low cost and high *** mixture of metal powder and binder goes through heating,extrusion,debinding and sintering processes to produce the compact finished ***,it is generally believed that parts produced by FDMS possess poor and anisotropic tensile properties,which always attributes to the weak interlayer *** current work aimed to enhance tensile properties and better understand the anisotropic fracture behavior of the 316L stainless steel prepared by *** process optimization,the yield strength and ultimate tensile strength obtained in this work are increased by 26.1%and 15.2%,based on the highest performance reported in previous *** to the ultimate tensile strength,the performance difference between the horizontal and vertical directions has been reduced to 27%.Furthermore,the experimental results indicated that the clustered irregular shape holes evolved from primitive voids prefer to distribute in the build direction,resulting in anisotropic tensile *** is suggested that the mechanical properties could be improved by applying a smaller extrusion diameter and rolling-assisted *** addition,the current FDMS parts show qualified performance for producing the customized and small batch components.

关键词： Fused deposition modelling 316L stainless steel Anisotropy Mechanical properties Fracture behaviour