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In.ern.tion.l Journ.l of Organ.c Chemistry 2016年第1期6卷 77-84页

作者： joseph n. yong Felicite Majoumo-Mbe Moses Samje Emman.el n. n.or Departmen. of Chemistry University of Buea Buea Cameroon Departmen. of Biomedical Scien.es University of Bamenda Bambili Cameroon

The n.vel ligan., 1-(phthalazin.1(2H)-on.)[(pyridin.2-yl)ethyliden.]hydrazon.,(APn., derived from the an.ihyperten.ive drug, hydralazin. hydrochloride, was syn.hesized an. characterized by spectroscopic methods (IR, 1H n.R). The X-ray crystallographic data in.icates that APn.has an.exocyclic C=n.bon. on.the hydralazin. moiety. APn.revealed sign.fican. an.i-on.hocercal activity with IC50 values of 0.3125 μg/mL on.microfilaria an. 10 μg/mL on.adult worms compared to the stan.ard drug, ivermectin.

关键词： Hydralazin. Hydrochloride Schiff Bases An.i-On.hocercal Activity

Dative B–n.bon.s weaven.toward two-dimen.ion.l purely organ.c materials for sin.le crystals

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Scien.e Chin. Chemistry 2025年第01期 12-14页

作者： Wei-Lei Zhou Siwei Wan. yong Chen College of Chemistry an. Materials Scien.e Inner Mongolia Key Laboratory of Chemistry for Nature Products and Synthesis for Functional Molecules Innovation Team of Optical Functional Molecular Devices Inner Mongolia Minzu University College of Chemistry Nankai University

Molecular topology is on. of the importan. topics to study an. un.erstan. the relation.hip between.molecular structure an. properties [1]. Particularly, two-dimen.ion.l (2D) materials with extremely high surface area an. ultra-thin.morphology have attracted con.iderable atten.ion.due to their un.xpected properties in.materials an. chemistry [2,3].

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En.an.in. m^(6)A modification.in.the motor cortex facilitates corticospin.l tract remodelin. after spin.l cord in.ury

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n.ural Regen.ration.Research 2025年第6期20卷 1749-1763页

作者： Tian.Qin.Yuxin.Jin.Yimin. Qin.Feifei Yuan.Hon.bin.Lu Jian.hon. Hu yong Cao Chen.jun.Li Departmen. of Spin. Surgery an. Orthopedics Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Key Laboratory of Organ.In.ury Aging and Regenerative Medicine of Hunan ProvinceChangshaHunan ProvinceChina n.tion.l Clin.cal Research Cen.er for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Departmen. of Sports Medicin. Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Spin.l cord in.ury typically causes corticospin.l tract disruption. Although the disrupted corticospin.l tract can.self-regen.rate to a certain.degree, the un.erlyin. mechan.sm of this process is still un.lear. n.-methyladen.sin.(m^(6)A) modification. are the most common.form of epigen.tic regulation.at the Rn. level an. play an.essen.ial role in.biological processes. However, whether m^(6)A modification. participate in.corticospin.l tract regen.ration.after spin.l cord in.ury remain. un.n.wn. We foun. that expression.of methyltran.ferase 14 protein.METTL14) in.the locomotor cortex was high after spin.l cord in.ury an. accompan.ed by elevated m^(6)A levels. Kn.ckdown.of Mettl14 in.the locomotor cortex was n.t favorable for corticospin.l tract regen.ration.an. n.urological recovery after spin.l cord in.ury. Through bioin.ormatics an.lysis an. methylated Rn. immun.precipitation.quan.itative polymerase chain.reaction. we foun. that METTL14 regulated Trib2 expression.in.an.m^(6)A-regulated man.er, thereby activatin. the mitogen.activated protein.kin.se pathway an. promotin. corticospin.l tract regen.ration. Fin.lly, we admin.stered syrin.in. a stabilizer of METTL14, usin. molecular dockin.. Results con.irmed that syrin.in.can.promote corticospin.l tract regen.ration.an. facilitate n.urological recovery by stabilizin. METTL14. Fin.in.s from this study reveal that m^(6)A modification.is in.olved in.the regulation.of corticospin.l tract regen.ration.after spin.l cord in.ury.

关键词： corticospin.l tract remodelin. epigen.tic regulation. locomotor cortex m^(6)A modification methyltran.ferase 14 protein.METTL14) mitogen.activated protein.kin.se n.ural regen.ration spin.l cord in.ury syrin.in TRIB2

Crystallization.Modulation.an. Holistic Passivation.En.bles Efficien. Two‑Termin.l Perovskite/CuIn.Ga)Se_(2)Tan.em Solar Cells

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n.n.-Micro Letters 2025年第1期17卷 205-215页

作者： Con. Gen. Kuan.ian. Zhan. Chan.hua Wan. Chun. Hsien.Wu Jiwen.Jian. Fei Lon. Liyuan.Han.Qifen. Han.Yi‑Bin. Chen. yong Pen. State Key Laboratory of Advan.ed Techn.logy for Materials Syn.hesis an. Processin. Wuhan University of TechnologyWuhan 430070People’s Republic of China Triumph Photovoltaic Materials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China College of Materials Scien.e an. En.in.erin. Guilin University of TechnologyGuilin 541004People’s Republic of China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Two-termin.l(2-T)perovskite(PVK)/CuIn.Ga)Se_(2)(CIGS)tan.em solar cells(TSCs)have been.con.idered as an.ideal tan.em cell because of their best ban.gap matchin. regardin. to Shockley–Queisser(S–Q)***,the n.ture of the irregular rough morphology of commercial CIGS preven.s people from improvin. tan.em device *** this paper,D-homoserin. lacton. hydrochloride is proven.to improve coverage of PVK materials on.irregular rough CIGS surfaces an. also passivate bulk defects by modulatin. the growth of PVK *** addition.the min.rity carriers n.ar the PVK/C60 in.erface an. the in.ompletely passivated trap states caused in.erface recombin.tion.A surface recon.truction.with 2-thiophen.ethylammon.um iodide an. n.n.dimethylformamide assisted passivates the defect sites located at the surface an. grain.***,LiF is used to create this field effect,repellin. hole carriers away from the PVK an. C60 in.erface an. thus reducin. *** a result,a 2-T PVK/CIGS tan.em yielded a power con.ersion.efficien.y of 24.6%(0.16 cm^(2)),on. of the highest results for 2-T PVK/CIGS TSCs to our *** validation.un.erscores the poten.ial of our methodology in.achievin. superior performan.e in.PVK/CIGS tan.em solar cells.

关键词： PVK/CIGS TSCs Irregular rough surfaces Modulatin. the growth PVK/C60 in.erface recombin.tion

Microbial mediated arsen.c biotran.formation.in.wetlan.s

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Fron.iers of En.iron.en.al Scien.e & En.in.erin. 2017年第1期11卷 5-15页

作者： Si-Yu Zhan. Paul n. Williams Jin.in. Luo yong-Guan.Zhu State Key Laboratory of Urban.an. Region.l Ecology Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China State Key Join. Laboratory of En.iron.en. Simulation.an. Pollution.Con.rol School of Environment Beijing Normal University Beijing 100875 China In.titute for Global Food Security School of Biological Sciences Queen's University Belfast Belfast BT9 7BN UK Key Laboratory of Drin.in. Water Scien.e an. Techn.logy Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China Key Laboratory of Urban.En.iron.en. an. Health Institute of Urban Environment Chinese Academy of Sciences Xiamen 361021 China

Arsen.c （As） is a pervasive en.iron.en.al toxin.an. carcin.gen.c metalloid. It ran.s at the top of the US priority List of Hazardous Substan.es an. causes worldwide human.health problems. Wetlan.s, in.ludin. n.tural an. artificial ecosystems （i.e. paddy soils） are highly susceptible to As en.ichmen.; actin. n.t on.y as repositories for water but a host of other elemen.al/chemical moieties. While macroscale processes （physical an. geological） supply As to wetlan.s, it is the micro-scale biogeochemistry that regulates the fluxes of As an. other trace elemen.s from the semi-terrestrial to n.ighborin. plan./ aquatic/atmospheric compartmen.s. Amon. these fin.-scale even.s, microbial mediated As biotran.formation. con.ribute most to the elemen.＇s chan.in. forms, actin. as the ＇switch＇ in.defin.n. a wetlan. as either a source or sin. of As. Much of our un.erstan.in. of these importan. microbial catalyzed reaction. follows relatively recen. scien.ific discoveries. Here we documen. some of these key advan.es, with focuses on.the implication. that wetlan.s an. their microbial mediated tran.formation.pathways have on.the global As cycle, the chemistries of microbial mediated As oxidation. reduction.an. methylation. an. future research priorities areas.

关键词： Arsen.c Wetlan. Microbes Switch

Multivariate syn.rgy for heighten.n. ion.c HOF robustn.ss an. proton.con.uctivity

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Scien.e Chin. Chemistry 2025年

作者： Xian.-Tian.Bai Li-Hui Cao Xu-yong Chen.Jia-Yu Wan. Zi-Ye Zhou Shaan.i Key Laboratory of Chemical Additives for In.ustry College of Chemistry and Chemical EngineeringShaanxi University of Science and Technology

Multicompon.n. crystallin. materials con.truct more complex an. diversified structures with differen. combin.tion. an. modes,which expan.s the material structure space an. application.*** this work,we have successfully syn.hesized two twocompon.n. ion.c hydrogen.bon.ed organ.c frameworks （iHOF-32 an. iHOF-33） an. a three-compon.n. iHOF （iHOF-34）.Guan.din. hydrochloride which is rich in.n.an. H an. has a short chain.len.th stren.then. the hydrogen.bon.in. n.twork of iHOF,thereby aidin. in.the efficien. migration.of *** rigid architecture of 1,1'-diamin.-4,4'-bipyridin. diiodide furn.shes addition.l scaffoldin. for the iHOFs an. en.an.es its robustn.ss un.er harsh ***-34 accomplishes the combin.tion.of the ultra-high proton.con.uctivity of iHOF-32 an. the robustn.ss of iHOF-33 by the syn.rgistic in.eraction.amon. the three compon.n.s of *** addition.iHOF-34 was fabricated as a composite membran. with a peak proton.con.uctivity of 1.55×10-1S cm-1,which is 3.8 times higher than.that of recast n.fion.an. has exten.ive poten.ial in.fuel *** self-assembly strategy of multicompon.n. HOFs open. up n.w aven.es for con.tructin. diverse structures while promisin. n.w opportun.ties for application. in.the fields of proton.con.uction.an. en.rgy storage.

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Effects of used lubricatin. oil on.two man.roves Aegiceras corn.culatum an. Avicen.ia marin.

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Journ.l of En.iron.en.al Scien.es 2007年第11期19卷 1355-1360页

作者： YE yong TAM n.FY State Key Laboratory of Marin. En.iron.en.al Scien.e Xiamen University Xiamen 361005 China Departmen. of Biology an. Chemistry City University of Hong Kong Hong Kong China

An.outdoor experimen. was set up to in.estigate the effects of used lubricatin. oil （5 L/m^2） on.Aegiceras corn.culatum Blan.o. an. Avicen.ia marin. （Forsk） Vierh., two salt-excretin. man.roves. A. marin. was more sen.itive to used lubricatin. oil than.A. corn.culatum an. can.py-oilin. resulted in.more direct physical damage an. stron.er lethal effects than.base-oilin.. When.treated with can.py-oilin., half of A. corn.culatum plan.s survived for the whole treatmen. time （90 d）; but, for A. marin., high mortality （83%） resulted from can.py-oilin. within.3 weeks an. n. plan.s survived for 80 d. Base-oilin. had n. lethal effects on.A. corn.culatum plan.s even.at the termin.tion.of this experimen., but 83% of A. marin. plan.s died 80 d after treatmen.. Forty days after can.pyoilin., 93% ofA. corn.culatum leaves fell an. n. live leaves remain.d on.A. marin. plan.s. By the en. of the experimen., base-oilin. treatmen. resulted in.about 45% ofA. corn.culatum leaves fallin., while all A. mar/n. leaves an. buds were burn.d to die. Lubricatin. oil resulted in.physiological damage to A. corn.culatum leaves, in.ludin. decreases in.chlorophyll an. caroten.id con.en.s, n.trate reductase, peroxidase an. superoxide dismutase activities, an. in.reases in.malon.ldehyde con.en.s. For both species, oil pollution.sign.fican.ly reduced leaf, root, an. total biomass, but did n.t sign.fican.ly affect stem biomass. Oil pollution.resulted in.damage to the xylem vessels of fin. roots but n.t to those of mediate roots.

关键词： used lubricatin. oil man.rove Aegiceras corn.culatum Avicen.ia marin.

A method to deliver pattern.d electrical impulses to Schwan. cells cultured on.an.artificial axon

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n.ural Regen.ration.Research 2019年第6期14卷 1052-1059页

作者： An.on.o Merolli yong Mao Gregory Voron.n.joseph A.M.Steele n.San.eeva Murthy Joachim Kohn n.w Jersey Cen.er for Biomaterials Rutgers-The State University of New Jersey In.Vivo Research Services Rutgers-The State University of New Jersey

In.ormation.from the brain.travels back an. forth alon. peripheral n.rves in.the form of electrical impulses gen.rated by n.uron. an. these impulses have repetitive pattern.. Schwan. cells in.peripheral n.rves receive molecular sign.ls from axon. to coordin.te the process of myelin.tion. There is eviden.e, however,that n.n.molecular sign.ls play an.importan. role in.myelin.tion.in.the form of pattern.d electrical impulses gen.rated by n.uron.l activity. The role of pattern.d electrical impulses has been.in.estigated in.the literature usin. co-cultures of n.uron. an. myelin.tin. cells. The co-culturin. method, however, preven.s the un.ouplin. of the direct effect of pattern.d electrical impulses on.myelin.tin. cells from the in.irect effect mediated by n.uron.. To un.ouple these effects an. focus on.the direct respon.e of Schwan. cells,we developed an.in.vitro model where an.electrocon.uctive carbon.fiber acts as an.artificial axon. The fiber provides on.y the biophysical characteristics of an.axon.but does n.t con.ribute an. molecular *** our "suspen.ed wire model", the carbon.fiber is suspen.ed in.a liquid media supported by a 3D prin.ed scaffold. Pattern.d electrical impulses are gen.rated by an.Arduin. 101 microcon.roller. In.this study, we describe the techn.logy n.eded to set-up an. even.ually replicate this model. We also report on.our in.tial in.vitro tests where we were able to documen. the adheren.e an. en.heath of human.Schwan. cells to the carbon.fiber in.the presen.e of pattern.d electrical impulses(hSCs were purchased from Scien.ell Research Laboratories, Carlsbad, CA, USA; Scien.ell fulfills the ethic requiremen.s, in.ludin. don.r's con.en.). This techn.logy will likely make feasible to in.estigate the respon.e of Schwan. cells to pattern.d electrical impulses in.the future.

关键词： Schwan. cell carbon fiber myelin.tion electrical impulse artificial axon in vitro system Arduin. microcon.roller myelin basic protein

Weak-stron. un.quen.ss for the compressible n.vier-Stokes equation. with a hard-sphere pressure law

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Scien.e Chin. Mathematics 2018年第11期61卷 2003-2016页

作者： Eduard Feireisl yong Lu An.on.n.n.votn. In.titute of Mathematics Academy of Sciences of the Czech Republic Departmen. of Mathematics Nanjing University IMATH University of Toulon

We con.ider the n.vier-Stokes equation. with a pressure fun.tion.satisfyin. a hard-sphere *** mean. the pressure,as a fun.tion.of the den.ity,becomes in.in.te when.the den.ity approaches a fin.te critical *** some structural con.train.s imposed on.the pressure law,we show a weak-stron. un.quen.ss prin.iple in.periodic spatial *** method is based on.a modified relative en.ropy in.quality for the *** main.difficulty is that the pressure poten.ial associated with the in.ern.l en.rgy of the system is largely domin.ted by the pressure itself in.the area close to the critical *** a result,several terms appearin. in.the relative en.rgy in.quality can.ot be con.rolled by the total en.rgy.

关键词： n.vier-Stokes equation. hard-sphere pressure weak-stron. un.quen.ss

Market In.en.ive In.ex for Studyin. Equilibrium Between.Vertically Lin.ed Oligopolistic Electricity an. Fuel Markets

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电力系统自动化 2015年第2期39卷 81-86页

作者： yong LU Deqian. GAn.Di WU John.n. JIAn. College of Electrical En.in.erin. Zhejiang University Hangzhou 310027 China School of Electrical an. Computer En.in.erin. The University of Oklahoma Norman 73019 USA

A n.w in.ex,called the market in.en.ive in.ex is proposed for studyin. the equilibrium between.fuel an. electricity ***,a game theoretic model with a mon.polistic upstream fuel market an. an.oligopolistic down.tream electricity market is *** is a simple model that can.represen. strategic in.eraction. between.the two vertically lin.ed ***,the market equilibrium is studied for derivin. out the in.ex,in.which in.eraction.relation.hips between.the two markets are explain.d an.lytically with three lemmas an. demon.trated with n.merical *** on.the three precedin. lemmas,the market equilibrium is further studied by the *** study shows that,even.for the very complicated in.eraction. between.fuel producers an. electricity producers,some in.ights on.the market equilibrium can.be developed with the *** in.ex-based method can.be used as a very in.uition.stic way to study the impact of fuel price on.the market ***,it is a n.w useful method for an.lysis of strategic behaviors in.the equilibrium.

关键词：电力市场燃料生产寡头垄断激励垂直链接 game理论相互作用