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柴达木盆地北缘大柴旦地区古生代花岗岩锆石SHRIMP定年

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岩石学报 2007年第8期23卷 1861-1875页

作者：吴才来郜源红吴锁平陈其龙 joseph l.wooden Frank K.MAZADAB Chris MATTINSON 中国地质科学院地质研究所火成岩研究室北京100037 美国斯坦福大学斯坦福加里佛尼亚94305

大柴旦地区是柴北缘古生代超高压带的重要组成部分,与超高压岩石相伴的花岗岩十分发育。这些花岗岩具有两类不同的岩石地球化学特征,Ⅰ类以 Na_2O/K_2O 比值小于1、明显的负 Eu 异常和低 Sr、高 Y 为特征,具有 S-型花岗岩的属性,Ⅱ类以 ... 详细信息

大柴旦地区是柴北缘古生代超高压带的重要组成部分,与超高压岩石相伴的花岗岩十分发育。这些花岗岩具有两类不同的岩石地球化学特征,Ⅰ类以 Na_2O/K_2O 比值小于1、明显的负 Eu 异常和低 Sr、高 Y 为特征,具有 S-型花岗岩的属性,Ⅱ类以 Na_2O/K_2O 比值大于1、弱负 Eu 异常到正 Eu 异常和高 Sr、低 Y 为特征,具有Ⅰ-型花岗岩的属性,反映了它们的源岩及成因上的差异。锆石 SHRIMP U—Ph 定年结果表明,大柴旦地区花岗岩的年龄可分为三组,第一组年龄为446.3±3.9Ma,第二组年龄分别为408.6±4.4Ma、403.3±3.8Ma、401.8±3Ma,第三组年龄分别为374.5±1.6Ma、372±2.1Ma。结合区域地质特征,我们认为,第一组年龄可能反映了柴达木陆块与中南祁连板块碰撞的时代,第二组年龄可能反映了深俯冲地下的板块由于拆沉而折返的时代,第三组年龄可能反映了碰撞隆起后造山带上不同块体之间的伸展、滑塌的时代。

关键词：花岗岩锆石SHRIMP U-Pb定年大柴旦柴北缘

北阿尔金巴什考供-斯米尔布拉克花岗杂岩特征及锆石SHRIMPU-Pb定年

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中国科学（D辑） 2007年第1期37卷 10-26页

作者：吴才来姚尚志曾令森杨经绥 joseph l.wooden 陈松永 Frank K.Mazadab 中国地质科学院地质研究所安徽地质调查院 Stanford University CA94305USA

北阿尔金巴什考供-斯米尔布拉克杂岩体位于巴什考供盆地北缘,呈东西向展布,宽约2～6km,长约30km,出露面积约140km2.主要由灰黑色石英闪长岩、灰白色花岗岩、粉红色花岗岩和花岗伟晶岩组成.围岩为前寒武系片岩、变质泥岩及变质凝灰岩.岩... 详细信息

北阿尔金巴什考供-斯米尔布拉克杂岩体位于巴什考供盆地北缘,呈东西向展布,宽约2～6km,长约30km,出露面积约140km2.主要由灰黑色石英闪长岩、灰白色花岗岩、粉红色花岗岩和花岗伟晶岩组成.围岩为前寒武系片岩、变质泥岩及变质凝灰岩.岩石地球化学特征表明,石英闪长岩属钙碱性系列,具有Ⅰ型花岗岩的属性;而粉红色和灰白色花岗岩属高钾钙碱性系列,具有S型花岗岩的属性.锆石SHRIMP定年结果表明,石英闪长岩的年龄为(481.6±5.6)Ma,而灰白色花岗岩和粉红色花岗岩的年龄在误差范围内基本一致,分别为(437.0±3.0)～(433.1±3.4)Ma和(443±11)～(434.6±1.6)Ma.结合区域地质特征,认为石英闪长岩可能形成于洋壳俯冲环境,而灰白色和粉红色花岗岩可能形成于碰撞后环境.

关键词：石英闪长岩花岗岩锆石SHRIMP U-Pb定年巴什考供-斯米尔布拉克

柴达木盆地北缘古生代超高压带中花岗质岩浆作用

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地质学报 2004年第5期78卷 658-674页

作者：吴才来杨经绥许志琴 joseph l.wooden Trevor IRElAND 李海兵史仁灯孟繁聪陈松永 Harold PERSING Anders MEIBOM 中国地质科学院地质研究所大陆动力学实验室北京100037 美国斯坦福大学斯坦福加里佛尼亚94305

祁连南缘古生代超高压变质带 (榴辉岩年龄为 4 6 6～ 4 95 Ma)上一套中高级变质岩系 (达肯大坂片麻岩 )中存在三类花岗岩组合 : 类 :石英二长闪长岩 -花岗闪长岩 -二长花岗岩 , 类 :二长花岗岩 -二云母花岗岩-含白云母花岗岩 -正长花岗... 详细信息

祁连南缘古生代超高压变质带 (榴辉岩年龄为 4 6 6～ 4 95 Ma)上一套中高级变质岩系 (达肯大坂片麻岩 )中存在三类花岗岩组合 : 类 :石英二长闪长岩 -花岗闪长岩 -二长花岗岩 , 类 :二长花岗岩 -二云母花岗岩-含白云母花岗岩 -正长花岗岩 , 类 :花岗闪长岩 -二长花岗岩 -黑云母花岗岩。类岩石组合中的二长花岗岩锆石SHRIMP年龄为 4 73Ma, 类岩石组合中的正长花岗岩锆石 SHRIMP年龄为 4 4 6 Ma, 类岩石组合中的二长花岗岩锆石 SHRIMP年龄为 397Ma。从三类花岗岩组合的组成矿物来看 , 类和类的矿物组合主要为斜长石、角闪石、石英、碱性长石、黑云母 , 类的矿物组合为钾长石、石英、白云母、黑云母、斜长石 ;从岩石地球化学特征上看 , 类和类花岗岩为型花岗岩 ,岩石的 Si O2 =6 1%～ 6 9% ,Na2 O/ K2 O>1,ANK1,δEu=0 .1～ 0 .3;从构造环境上看 , 类花岗岩形成于岛弧环境或活动大陆边缘 , 类花岗岩形成于同碰撞 , 类花岗岩形成于碰撞后。结合区域地质特征 ,我们认为 ,早奥陶世 ,南祁连洋板块向北俯冲于祁连陆块之下 ,规模不大的南祁连洋很快闭合 ,但俯冲下去的大洋板块仍拖动柴达木陆块继续俯冲 ,俯冲?

关键词：花岗岩俯冲 SHRIMP 岩石组合锆石岩组榴辉岩块体上浮底部

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北祁连洋早古生代双向俯冲的花岗岩证据

中国地质 2006年第6期33卷 1197-1208页

作者：吴才来姚尚志杨经绥曾令森陈松永李海兵戚学祥 joseph l. wooden Frank K.Mazdab 中国地质科学院地质研究所北京100037 安徽省地质调查院安徽合肥230001 斯坦福大学

笔者主要对北祁连山中段的牛心山岩体、民乐窑沟岩体进行了锆石SHRIMP定年研究。结果表明:牛心山花岗岩的年龄为476 Ma,民乐窑沟花岗闪长岩的年龄为463 Ma。岩石地球化学显示,两岩体均具有大陆活动边缘的岩浆作用特征,结合岩体产出的区... 详细信息

笔者主要对北祁连山中段的牛心山岩体、民乐窑沟岩体进行了锆石SHRIMP定年研究。结果表明:牛心山花岗岩的年龄为476 Ma,民乐窑沟花岗闪长岩的年龄为463 Ma。岩石地球化学显示,两岩体均具有大陆活动边缘的岩浆作用特征,结合岩体产出的区域构造位置及区域地质资料,笔者认为早古生代北祁连洋板块分别发生了向南、向北俯冲,其中向南俯冲形成牛心山花岗岩(476 Ma),向北俯冲,形成了民乐窑沟花岗岩侵入体(463 Ma)。

关键词：花岗岩锆石SHRIMP U-Pb定年双向俯冲北祁连

北阿尔金斯米尔布拉克凹陷南带花岗杂岩特征及锆石SHRIMP定年

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北阿尔金斯米尔布拉克凹陷南带花岗杂岩特征及锆石SHRIMP定年

Disparate outcomes in Hispanic patients with metabolic dysfunctionassociated steatotic liver disease/steatohepatitis and type 2 diabetes: large cohort study

2004年全国岩石学与地球动力学研讨会

作者：吴才来 joseph l.wooden 杨经绥陈松永李海兵戚学祥中国地质科学院地质研究所大陆动力学实验室美国斯坦福大学

北阿尔金红柳沟地区出露一套早古生代俯冲碰撞杂岩,其中分布着不同类型的花岗岩类。其中,斯米尔布拉克凹陷南带花岗杂岩体呈近东西向断续分布,长约49公里,出露面积约90平方公里,与围岩之间为明显的侵入接触关系,接触界线为不规则的波状... 详细信息

北阿尔金红柳沟地区出露一套早古生代俯冲碰撞杂岩,其中分布着不同类型的花岗岩类。其中,斯米尔布拉克凹陷南带花岗杂岩体呈近东西向断续分布,长约49公里,出露面积约90平方公里,与围岩之间为明显的侵入接触关系,接触界线为不规则的波状、锯齿状。围岩为前寒武系砂岩、片岩、泥岩及凝灰质砂岩。该杂岩体主要由巨斑花岗岩、中粗粒杂色花岗岩和中细粒红色花岗岩组成。杂岩体的主元素含量变化不大,SiO为65.14%—75.66%,全碱含量为7.49-8.96%,其中的NaO的含量低于KO的含量,KO/NaO比值大于1,为1.12-2.68,岩石的里特曼指数为1.83-2.81(平均为2.34),CIPW标准矿物计算均出现刚玉(AC),含量为0.77—3.93(平均为1.78),大多数大于1,说明岩石铝过饱和;杂岩体的稀土总量变化较大,变化于89.44×10—335.28×10之间,不同岩石类型均有负铕异常,且从巨斑花岗岩→中粗粒杂色花岗岩→红色花岗岩,负铕异常越来越明显,表现在Eu/Eu值由0.65→0.49→0.35。在微量元素蛛网图上,所有样品的微量元素丰度均高于原始地幔值1—1000倍,并具有相似的配分模式,即在Ba、Nb、Sr、P、Ti处呈明显的低谷,显示出S型花岗岩的特征。由巨斑花岗岩→杂色花岗岩→红色花岗岩,微量元素的丰度逐渐变小,Ba、Nb、Sr、P、Ti负异常也越来越明显。野外观察表明,巨斑花岗岩与杂色花岗岩之间为逐渐过渡,而红色花岗岩明显地侵入到杂色花岗岩之中。因此,选择该杂岩体中的巨斑花岗岩和中细粒红色花岗岩做了锆石的SHRIMP U-Pb定年研究。对巨斑花岗岩共测定了17颗锆石,除含有继承性锆石核的锆石年龄较大外(分别为720.3±7.3Ma、1032.8±8.9Ma、1597.8±14.3Ma),其余的锆石年龄变化于445.6±4.5Ma—497.7±4.1Ma,平均为470±12Ma,Pb/U—Pb/U谐和年龄上交点年龄为1561±36Ma,可能反映了花岗岩的源岩时代,下交点年龄为459±17Ma,可能反映了花岗岩的结晶年龄,考虑下交点的年龄误差范围,仍取470±12Ma作为岩体侵位结晶年龄。红色花岗岩的大多数锆石年龄变化于416.1±4.6Ma—471.8±6.1Ma,平均为442.1±6.7Ma,少数锆石年龄较老,如7号锆石年龄最大,为2717.4±24.2Ma,10号锆石为1905.5±20.2Ma,28号锆石为792.2±7.7Ma。7号和10号锆石为粒状,28号锆石为短柱状。尽管这些锆石的年龄不同,但Th/U比值均较大,为0.43—1.78,除10号和28号锆石的Th/U比分别为0.43和0.45外,其余锆石均大于0.5。结合区域地质特征,我们认为,该杂岩体形成于陆陆碰撞的构造环境。

关键词：花岗岩锆石SHRIMP定年斯米尔布拉克北阿尔金

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World Journal of Diabetes 2024年第5期15卷 886-897页

作者： joseph Matthew Gosnell George Golovko Esteban Arroyave Akshata Moghe Michael l Kueht Omar AbdulSaldarriaga Kevin H McKinney Heather l Stevenson Monique R Ferguson Department of Pathology University of Texas Medical BranchGalvestonTX 77555United States Department of Pharmacology&Toxicology University of Texas Medical BranchGalvestonTX 77555United States Department of Medicine University of Texas Health Science Center at HoustonHoustonTX 77030United States Department of Surgery University of Texas Medical BranchGalvestonTX 77555United States Center for Tropical Diseases Department of Internal MedicineUniversity of Texas Medical BranchGalvestonTX 77555United States Department of Internal Medicine University of Texas Medical BranchGalvestonTX 77555United States

BACKGROUND Metabolic dysfunction-associated steatotic liver disease(MASlD)and metabolic dysfunction-associated steatohepatitis(MASH)are a growing health burden across a significant portion of the global patient ***,these conditions seem to have disparate rates and outcomes between different ethnic *** combination of MASlD/MASH and type 2 diabetes increases the risk of hepatocellular carcinoma(HCC),and Hispanic patients experience the greatest burden,particularly those in South *** To compare outcomes between Hispanic and non-Hispanic patients in the United States,while further focusing on the Hispanic population within Southeast Texas to determine whether the documented disparity in outcomes is a function of geographical circumstance or if there is a more widespread reason that all clinicians must account for in prognostic *** This cohort analysis was conducted with data obtained from TriNetX,llC(“TriNetX”),a global federated health research network that provides access to deidentified medical records from healthcare organizations *** cohort networks were used:University of Texas Medical Branch(UTMB)hospital and the United States national database collective to determine whether disparities were related to geographic regions,like Southeast *** This study findings revealed Hispanics/latinos have a statistically significant higher occurrence of HCC,type 2 diabetes mellitus,and liver fibrosis/cirrhosis in both the United States and the UTMB Hispanic/latino *** mortality in Hispanics/latinos was lower within the United States group and not statistically elevated in the UTMB *** This would appear to support that Hispanic patients in Southeast Texas are not uniquely affected compared to the national Hispanic population.

关键词： Metabolic dysfunction-associated steatotic liver disease Metabolic dysfunction-associated steatohepatitis Hispanic Diabetes mellitus TriNetX Non-alcoholic fatty liver disease Non-alcoholic steatohepatitis Steatotic liver disease Hepatocellular carcinoma

Serum ferritin and the risk of early-onset colorectal cancer

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3496-3506页

作者： Adam l Urback Kylee Martens Hannah Stowe McMurry Emerson Y Chen Caitlin Citti Anil Sharma Adel Kardosh joseph J Shatzel Division of Internal Medicine Oregon Health&Science UniversityPortlandOR 97239United States Division of Hematology and Medical Oncology Knight Cancer InstituteOregon Health&Science UniversityPortlandOR 97239United States Division of Gastroenterology&Hepatology Oregon Health&Science UniversityPortlandOR 97239United States

BACKGROUND The incidence of early-onset colorectal cancer(EO-CRC)is rising in the United States,and is often diagnosed at advanced *** serum ferritin is often incidentally discovered in young adults,however,the indication for endoscopy in EO-CRC is *** To compare serum ferritin between patients with EO-CRC and healthy controls(HCs),and examine the association of serum ferritin in EO-CRC with patient-and disease-specific *** A retrospective study of patientsly-diagnosed EO-CRC was conducted from 1/2013-12/*** were included if serum ferritin was measured within 2 years prior to 1 year following CRC histologic *** supplement the analysis,a cohort of HCs meeting similar inclusion and exclusion criteria were identified for comparison.A sensitivity analysis including only patients with serum ferritin obtained at or before diagnosis was separately performed to minimize risk of *** Among 85 patients identified with EO-CRC(48 females),the median serum ferritin level was 26 ng/ml(rangel).Compared to HCs(n=80211),there were a higher proportion of individuals with EO-CRC with serum ferritinl(female 65%,male 40%)versus HCs(female 32.1%,male 7.2%)age 29-39 years(P=0.002 and Ply).Stage IV disease was associated with significantly higher serum ferritin compared to less advanced stages(Plower than levels obtained after *** findings were confirmed in the sensitivity *** Severe iron deficiency may indicate an increased risk of EO-CRC,particularly at earlier *** studies defining the optimal serum ferritin threshold and routine incorporation of serum ferritin in screening algorithms is essential to develop more effective screening strategies for EO-CRC.

关键词： Early-onset Young-onset Colorectal cancer Age Ferritin Iron deficiency

Bashikaogong-Shimierbulake granitic complex, north Altun, NW China:Geochemistry and zircon SHRIMP ages

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Science China Earth Sciences 2006年第12期49卷 1233-1251页

作者： joseph l. wooden Frank K. Mazdab Stanford University

The Bashikaogong-Shimierbulake granitoid complex is about 30 km long and 2―6 km wide, with an area of 140 km2, located at the north margin of the Bashikaogong Basin in the north Altun terrain. It intruded into schist, metapelite and metatuff of Precambrian ages. This granitoid complex consists of darkish quartz diorite, grey granite, pink granite and pegmatite. Geochemically, the quartz diorite has I-type granite affinity and belongs to Calc-alkaline sereies, and the other gran- ites have S-type affinity and to high-K calc-alkaline series. Zircon SHRIMP U-Pb dating shows that the quartz diorite has a bigger age than those of other granites, which is 481.6±5.6 Ma for quartz diorite, 437.0±3.0 Ma―433.1±3.4 Ma for grey granite and 443±11 Ma―434.6±1.6 Ma for pink granite, re- spectively. Combined with regional geology, we think that the quartz diorite formed in tectonic envi- ronment related to oceanic crust subduction and the granites in post-collision.

关键词： quartz diorite,granite,zircon SHRIMP U-Pb dating,Bashikaogong-Shimierbulake.

Machine-learning-Assisted Design of Deep Eutectic Solvents Based on Uncovered Hydrogen Bond Patterns

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Engineering 2024年第8期39卷 74-83页

作者： Usman l.Abbas Yuxuan Zhang joseph Tapia Selim Md Jin Chen Jian Shi Qing Shao Department of Chemical and Materials Engineering University of KentuckyLexingtonKY 40506USA Department of Biosystems and Agricultural Engineering University of KentuckyLexingtonKY 40506USA Institute for Biomedical Informatics Department of Computer ScienceUniversity of KentuckyLexingtonKY 40506USA

Non-ionic deep eutectic solvents(DESs)are non-ionic designer solvents with various applications in catalysis,extraction,carbon capture,and ***,discovering new DES candidates is challenging due to a lack of efficient tools that accurately predict DES *** search for DES relies heavily on intuition or trial-and-error processes,leading to low success rates or missed *** that hydrogen bonds(HBs)play a central role in DES formation,we aim to identify HB features that distinguish DES from non-DES systems and use them to develop machine learning(Ml)models to discover new DES *** first analyze the HB properties of 38 known DES and 111 known non-DES systems using their molecular dynamics(MD)simulation *** analysis reveals that DES systems have two unique features compared to non-DES systems:The DESs have①more imbalance between the numbers of the two intra-component HBs and②more and stronger inter-component *** on these results,we develop 30 Ml models using ten algorithms and three types of HB-based *** model performance is first benchmarked using the average and minimal receiver operating characteristic(ROC)-area under the curve(AUC)*** also analyze the importance of individual features in the models,and the results are consistent with the simulation-based statistical ***,we validate the models using the experimental data of 34 *** extra trees forest model outperforms the other models in the validation,with an ROC-AUC of *** work illustrates the importance of HBs in DES formation and shows the potential of Ml in discovering new DESs.

关键词： Machine learning Deep eutectic solvents Molecular dynamics simulations Hydrogen bond Molecular design