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2007年ACC／AHA非心脏手术围手术期心血管评估与管理指南：实施概要

丛书名： Contemporary Cardiology

2005年

作者： joseph p. ornato Mary Ann peberdy

来源：畅想之星图书光盘版（南... 评论

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麻醉与镇痛 2010年第6期6卷 1-28页

作者： Lee A Fleisher Joshua A Beckman Kenneth A Brown Hugh Calkins Elliott Chaikof Kirsten E Fleischmann William K Freeman James B Froehlich Edward K Kasper Judy R Kersten Barbara Riegel John F Robb Sidney C Smith Alice K Jacobs Cynthia D Adams Jeffrey L Anderson Elliott M Antman Christopher E Buller Mark A Creager Steven M Ettinger David p Faxon Valentin Fuster Jonathan L Halperin Loren F Hiratzka Sharon A Hunt Bruce W Lytle Rick Nishimura joseph p ornato Richard L page Lynn G Tarkington Clyde W Yancy

美国心脏病学院镁国心脏协会工作组有关实践指南的一份报告（编写委员会对2002年非心脏手术围手术期心血管评估指南的修改）

关键词：非心脏手术管理指南血管评估围手术期 ACC/AHA 美国心脏病学院实践指南心脏协会

Calculation of First Sound Speed in Liquid Helium

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Chinese physics Letters 1999年第4期16卷 276-278页

作者： pAO Lu joseph p.Foy Department of physics and Astronomy Arizona State UniversityTempeArizona 85287USA

The speed of first sound in liquid helium II is calculated quantum *** calculation is made by using a modified version of Brueckner and Sawada’s method[***.106(1959)1128]and is based on the postulate that the hard co... 详细信息

关键词： quantum Sound sound

Strategies to enhance monoclonal antibody uptake and distribution in solid tumors

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Cancer Biology & Medicine 2021年第3期18卷 649-664页

作者： Brandon M.Bordeau joseph p.Balthasar Department of pharmaceutical Science University at BuffaloBuffaloNY 14214USA

Despite the significant resources dedicated to the development of monoclonal antibody(m Ab)therapies for solid tumors,the clinical success,thus far,has been *** efficacy of m Ab in solid tumors likely relates to unique aspects of tumor *** tumors have an aberrant vasculature and a dense extracellular matrix that slow both the convective and diffusive transport of m Abs into and within *** m Abs that are directed against cellular antigens,high antigen expression and rapid antigen turnover can result in perivascular cells binding to and eliminating a significant amount of extravasated m Ab,limiting m Ab distribution to portions of the tumor that are distant from functional *** preclinical investigations have reported strategies to improve m Ab uptake and distribution;however,to our knowledge,none have translated into the ***,we provide an overview of several barriers in solid tumors that limit m Ab uptake and distribution and discuss approaches that have been utilized to overcome these barriers in preclinical studies.

关键词： Solid tumors antibody uptake and distribution monoclonal antibody antibody-drug conjugate

Comparative study of mechanical, corrosion and erosion-corrosion properties of cast hyper-duplex and super-duplex stainless steels

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International Journal of Minerals,Metallurgy and Materials 2020年第7期27卷 954-961页

作者： p.Nithin Raj p.K.Navaneethkrishnan K.Sekar M.A.joseph Department of Mechanical Engineering National Institute of TechnologyCalicutIndia

Duplex stainless steels(DSSs)used in subsea structures and desalination industries require high corrosion and erosion resistance as well as excellent mechanical *** newly introduced cast duplex grade ASTM A8907 A has a unique composition and is expected to have a much better resistance to corrosion and erosion compared with the super-duplex grades 5 A and 6 *** work is a comparative study of the mechanical properties,corrosion,and erosion-corrosion resistance of super-duplex grades 5 A and 6 A and the hyper-duplex grade 7 *** three DSSs exhibited equiaxial austenite islands in the ferrite matrix and balanced phase *** hardness of the grade 7 A was nearly 15%higher than those of the super-duplex grades,which is attributed to the effect of the higher contents of W and Mn in 7 *** impact toughness of grade 7 A was found to be lower than those of the super-duplex grades due to the carbide precipitation resulting from the partial substitution of Mo with *** oxide layer strengthening effect of rare earth elements and the higher pitting resistance equivalent number(pREN)of grade7 A resulted in higher corrosion *** harder and more passive grade 7 A showed a 35%lower material loss during erosion-corrosion.

关键词： hyper-duplex stainless steels erosion−corrosion electrochemical corrosion marine environment super-duplex stainless steels

Morphometric aspects of a small tropical mountain river system,the southern Western Ghats,India

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International Journal of Digital Earth 2010年第2期3卷 135-156页

作者： Jobin Thomas Sabu joseph K.p.Thrivikramaji Department of Environmental Sciences University of KeralaThiruvananthapuram 695581KeralaIndia Department of Geology University of KeralaThiruvananthapuram 695581KeralaIndia

The Muthirapuzha watershed(MW)is one among the major tributaries of periyarthe longest west flowing river in Kerala,India.A morphometric analysis was carried out to determine the spatial variations in the drainage characteristics of MW and its 14 fourth order sub-watersheds(SW1SW14)using Survey of India topographic maps and Landsat ETM*** study revealed that the watershed includes a sixth order stream and lower order streams dominate the *** did indicate that rainfall has a significant role in the drainage development whereas structure and relief of rocks dictate the drainage *** asymmetry in the drainage distribution is correlated with the tectonic history of the Munnar plateau in the late paleocene *** watershed is moderate to well-drained and exhibited a geomorphic maturity in its physiographic *** shape parameters revealed the elongated nature of MW and drainage network development in the ***,the analysis provided significant insight into the terrain *** study strongly brings to light,(a)the tendency of the watershed to soil loss and(b)the hydrological makeup of the subwatersheds,which combined helped to formulate a comprehensive watershed management plan.

关键词： morphometry digital earth Muthirapuzha watershed Western Ghats India

Assessment of soil erosion in a tropical mountain river basin of the southern Western Ghats,India using RUSLE and GIS

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Geoscience Frontiers 2018年第3期9卷 893-906页

作者： Jobin Thomas Sabu joseph K.p.Thrivikramji EWRE Department of Civil EngineeringIndian Institute of Technology MadrasChennai600036Tamil NaduIndia Department of Environmental Sciences University of KeralaThiruvananthapuram695581KeralaIndia Center for Environment and Development Thiruvananthapuram695013KeralaIndia

Revised Universal Soil Loss Equation(RUSLE) model coupled with transport limited sediment delivery(TLSD) function was used to predict the longtime average annual soil loss, and to identify the critical erosion-/deposition-prone areas in a tropical mountain river basin, viz., Muthirapuzha River Basin(MRB; area=271.75 km^2), in the southern Western Ghats, India. Mean gross soil erosion in MRB is 14.36 t ha^(-1) yr^(-1), whereas mean net soil erosion(i.e., gross erosion-deposition) is only 3.60 t ha^(-1) yr^(-1)(i.e., roughly 25% of the gross erosion). Majority of the basin area(~86%) experiences only slight erosion(positional environment for the eroded sediments(e.g., the terraces of stream reaches, the gentle plains as well as the foot slopes of the plateau scarps and the terrain with concordant summits). Although mean gross soil erosion rates in the natural vegetation belts are relatively higher, compared to agriculture, settlement/built-up areas and tea plantation, the sediment transport efficiency in agricultural areas and tea plantation is significantly high,reflecting the role of human activities on accelerated soil erosion. In MRB, on a mean basis, 0.42 t of soil organic carbon(SOC) content is being eroded per hectare annually, and SOC loss from the 4th order subbasins shows considerable differences, mainly due to the spatial variability in the gross soil erosion rates among the sub-basins. The quantitative results, on soil erosion and deposition, modelled using RUSLE and TLSD, are expected to be beneficial while formulating comprehensive land management strategies for reducing the extent of soil degradation in tropical mountain river basins.

关键词： Soil erosion RUSLE Transport limited sediment delivery Muthirapuzha river basin Western Ghats Kerala

Calreticulin surface presentation: a signal for natural killer cells to attack

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Signal Transduction and Targeted Therapy 2023年第9期8卷 3883-3884页

作者： Jasmine p.Castellanos joseph C.Genereux Microbiology Graduate program University of CaliforniaRiversideCA 92521USA Department of Chemistry University of CaliforniaRiversideCA 92521USA

In a recent article published in Nature,Sen Santara et *** a general mechanism that allows endoplasmic reticulum(ER)stress,a common response to many cellular dysfunctions,to signal to natural killer(NK)cells to destroy the stressed cell(Fig.1).1 This mechanism suggests that targeting this signaling pathway might serve as a common therapeutic approach to treat disparate diseases,including cancers and *** innate immune system recognizes molecular signa-tures that indicate threats to the organism,and transduces these signatures into an immune response to counter these *** part of the innate immune system,NK cells constitute a lymphoid immune cell type that kills infected or cancerous cells on the basis of their presentation of specific ligands or markers on the surface of abnormal cells.

关键词： killer surface

Sources, distribution, and risk assessment of organochlorine pesticides in Nairobi City, Kenya

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Journal of Environmental Sciences 2020年第10期32卷 178-185页

作者： Fred Ayodi Lisouza p.Okinda Owuor joseph O.Lalah Department of pure and Applied Chemistry Masinde Muliro UniversityP.O.Box 190Kakamega 50100Kenya Department of Chemistry Maseno UniversityP.O.Box 333Maseno 40105Kenya Department of Geochemistry&Enuironmental Chemistry Technical Uniuersity of KenyaP.O.Box 52428-00200NairobiKerya

The distribution and sources of organochlorine pesticides (OCps) in air and surface waters were monitored in Nairobi City using triolein-filled semipermeable membrane devices (Sp-MDs).The SpMDs were extracted by dialysis using n-hexane,followed by cleanup by adsorption chromatography on silica gel *** analysis was done by GC-ECD and confirmed by GC–*** of means was achieved by analysis of variance,followed by pair-wise comparison using the t-test (p≤0.05).The total OCps ranged between 0.018–1.277 ng/m^3 in the air andKibera>Industrial Area>City Square>Ngong’***,these were lower than the USEpA acceptable risks,10^(-6)–10^(-4).This study concluded that atmospheric OCps did not pose significant cancer risks to the residents.

关键词： Organochlorine pesticides(OCps) passive sampling Water-air fugacity ratio Sources and distribution Risk assessment

A cost-effective method to enhance adenoviral transduction of primary murine osteoblasts and bone marrow stromal cells

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Bone Research 2016年第2期4卷 91-100页

作者： Atum M Buo Mark S Williams Jaclyn p Kerr joseph p Stains Department of Orthopaedics University of Maryland School of Medicine Department of Microbiology and Immunology University of Maryland School of Medicine

We report here a method for the use of poly-L-lysine （pLL） to markedly improve the adenoviral transduction efficiency of primary murine osteoblasts and bone marrow stromal cells （BMSCs） in culture and in situ, which are typically difficult to transduce. We show by fluorescence microscopy and flow cytometry that the addition of pLL to the viral-containing medium significantly increases the number of green fluorescence protein （GFp）-positive osteoblasts and BMSCs transduced with an enhanced GFp-expressing adenovirus. We also demonstrate that pLL can greatly enhance the adenoviral transduction of osteoblasts and osteocytes in situ in ex vivo tibia and calvaria, as well as in long bone fragments. In addition, we validate that pLL can improve routine adenoviral transduction studies by permitting the use of low multiplicities of infection to obtain the desired biologic effect. Ultimately, the use of pLL to facilitate adenoviral gene transfer in osteogenic cells can provide a cost-effective means of performing efficient gene transfer studies in the context of bone research.

关键词： A cost-effective method to enhance adenoviral transduction of primary murine osteoblasts and bone marrow stromal cells pLL bone