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Bruch's membrane opening-minimum rim width and visual field loss in glaucoma:a broken stick analysis

international Journal of Ophthalmology(English edition) 2018年第5期11卷 828-834页

作者： Keun-Heung Park ji-Woong Lee jin-Mi kim Kouros Nouri-Mahdavi joseph Caprioli Department of Ophthalmology Pusan National University College of Medicine Biomedical Research institute Pusan National University Hospital Department of Biostatistics Clinical Trial CenterBiomedical Research InstitutePusan National University Hospital Stein Eye institute David Geffen School of Medicine at UCLA

AiM：To determine the Bruch＇s membrane opening-minimum rim width（BMO-MRW） tipping point where corresponding visual field（VF） damages become ***：A total of 85 normal subjects and 83 glaucoma patients（one eye per participant） were recruited for the *** of the patients had VF examinations and spectral-domain optical coherence tomography to measure the *** deviation values for 52 VF points were allocated to the corresponding sector according to the Garway-Heath distribution *** evaluate the relationship between VF loss and BMOMRW measurements,a ＂broken-stick＂ statistical model was *** tipping point where the VF values started to sharply decrease as a function of BMO-MRW measurements was estimated and the slopes above and below this tipping point were ***：A 25.9% global BMO-MRW loss from normative value was required for the VF loss to be ***,substantial BMO-MRW thinning in inferotemporal sector（33.1%） and relatively less BMO-MRW thinning in the superotemporal sector（8.9%） were necessary for the detection of the VF *** the tipping point,the slopes were close to zero throughout all of the sectors and the VF loss was unrelated to the BMO-MRW *** VF loss was related to the BMO-MRW loss below the tipping *** difference between the two slopes was statistically significant（P≤0.002）.CONCLUSiON：Substantial BMO-MRW loss appears to be necessary for VF loss to be detectable in patients with open angle glaucoma with standard achromatic perimetry.

关键词： Bruch's membrane opening-minimum rim width visual field loss structure function relationship broken stick model optical coherence tomography

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运动不耐受诊断标准:Bárány协会分类委员会共识文件

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神经损伤与功能重建 2022年第12期17卷 687-695页

作者：宋宁(译) 邢玥(译) 李康之(译) 金占国(审校) 杨旭(审校) Yoon-Hee Cha John F.Golding Behrang Keshavarz joseph Furman ji-Soo kim Jose A.Lopez-Escamez Måns Magnusson Bill J.Yates Ben D.Lawson Jeffrey P.Staab(顾问) Alexandre Bisdorff(顾问) 航天中心医院(北京大学航天临床医学院)神经内科北京大学首钢医院神经内科中国人民解放军空军特色医学中心眩晕中心明尼苏达大学神经病学系美国明尼苏达州明尼阿波里斯市威斯敏斯特大学社会科学学院心理学英国伦敦多伦多康复研究所-多伦多综合医院加拿大安大略省多伦多市瑞尔森大学心理学系加拿大安大略省多伦多市匹兹堡大学耳鼻咽喉科美国宾夕法尼亚州匹兹堡首尔大学神经病学系韩国首尔格拉纳达大学耳鼻咽喉科外科西班牙格拉纳达辉瑞公司/格拉纳达大学/安达卢西亚(GENyO)基因组与肿瘤研究中心基因组医学系耳科和神经科小组CTS495 PTS西班牙格拉纳达涅维斯圣女医院生物卫生研究所耳鼻喉科西班牙格拉纳达隆德大学耳鼻喉科瑞典隆德匹兹堡大学耳鼻喉科美国宾夕法尼亚州匹兹堡新伦敦海军潜艇基地海军潜艇医学研究实验室美国康涅狄格州格罗顿梅奥诊所精神心理学系美国明尼苏达州罗彻斯特 EmileMayrisch医疗中心神经内科卢森堡阿尔泽特河畔埃施

我们提出了运动不耐受(motion sickness,MS),视觉诱发运动不耐受(visually induced motion sickness,ViMS),运动病(motion sickness disorder,MSD)和视觉诱发运动病(visually induced motion sickness disorder,ViMSD)的诊断标准,这些标准将被纳入国际前庭疾病分类。MS和ViMS是一种正常生理反应,几乎所有人都可能出现,但在某些情况下,个体对这种反应的易感性和严重性过高则被认为是一种疾病。本文提供了对由躯体运动或视觉运动引起的症状和体征的评价标准及个体反应严重程度是否可构成疾病诊断的指南。MS和ViMS的诊断标准包括由于暴露于躯体运动或视觉运动所引发的不良反应,通常导致在以下方面出现严重程度大于最低限度的症状或体征:恶心和/或胃肠道功能紊乱、体温调节功能紊乱、觉醒水平改变、头晕和/或眩晕、头痛和/或眼疲劳。这些症状/体征在暴露于运动状态时出现,随着暴露时间延长而加重,最终随运动结束而消失。当相同或相似的刺激反复诱发MS或ViMS发作,其严重程度在反复暴露后没有明显减轻,且因症状/体征而调整活动状态、避免参与诱发不耐受的运动刺激或负性情绪反应时,即可诊断为MSD和ViMSD。MS/MSD和ViMS/ViMSD可以单独出现,也可同时出现。由躯体运动或视觉运动刺激诱发的症状严重程度个体差异较大,并且同一个体也会因年龄、适应能力及合并疾病的变化而发生改变。本文探讨了评估MS症状的主要方法,易出现MS和ViMS相关情境以及导致易感性增加相关的个体特征。对上述环境和个人因素特征的准确评估及理解,将有助于MSD和ViMSD的诊断优化。

关键词：躯体运动诊断标准胃肠道功能紊乱活动状态运动病眼疲劳疾病诊断 MS/MS

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拍卖行化身多元艺术空间——嘉德艺术中心

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设计家 2018年第1期 102-106页

作者： Marcel Holmberg Sun Ke Emily Liang Cecilia Lei Yingda Ahrens Mark Biemans kim Bjarke Catarina Canas Alicia Casals Michael Cavander Jeffrey Cheng Patrick Conway Dyno Du Nicolaz Frez Brian Fung Daniel Hawkins Xinran ji Philipp Kramer Emeline Laurencon Yuyang Lin Mavis Liu Wymen Lo Max Ma Rafael Merino John Murphey Marcin Olszowski Kevin Ou Kevin Park Yanyadech Phornphong Aaron Powers Klementina Savickaite jim Shi Chiara Storino joseph Tang Yang Tao Elena Yang Quentin Yiu Francis Young Lei Yu Danny Zhang Bruno Zhao Weiwei Zhang Yi Zhu Catarina Canas Brian Fung Paloma Hernaiz Marcel Holmberg Tait Kaplan Jaime Oliver joseph Tang Beijing institute of Architectural Design (BiAD) Beijing Buro Ole Scheeren MQ-Studio Shanghai(Hotel)

嘉德艺术中心紧邻紫禁城,作为一座全新的综合文化机构,将北京的古城韵味与现代大都会的蓬勃生机以及多元艺术融为一体.嘉德艺术中心是世界上第一个量身定制的拍卖行总部,在北京的中心创建了一个全新的多元艺术机构类型.建筑提供博物馆... 详细信息

嘉德艺术中心紧邻紫禁城,作为一座全新的综合文化机构,将北京的古城韵味与现代大都会的蓬勃生机以及多元艺术融为一体.嘉德艺术中心是世界上第一个量身定制的拍卖行总部,在北京的中心创建了一个全新的多元艺术机构类型.建筑提供博物馆硬件质量的展示空间和最先进的艺术品保护设施,同时也是一个灵活丰富的文化空间,与餐馆、酒店、公共交通基础设施结合在一起.

关键词：艺术中心拍卖行艺术空间化身交通基础设施机构类型文化空间量身定制

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CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi igor Boyko ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen jinhui Chen ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research institute Co. LtdBeijing Beijing institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China institute of Atomic Energy Beijing China jiliang University HangzhouZhejiang China Nuclear instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft institute Daresbury Cornell University IthacaNY CPPM(AMU/iPhU&CNRS/iNP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint institute for Nuclear Research(DLNP jiNR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(iP),resulting in an integrated luminosity of 13 ab^(-1)for two iPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

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