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Mortality and health care burden of Budd Chiari syndrome in the United States:A nationwide analysis(1998-2017)

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World Journal of Hepatology 2021年第6期13卷 686-698页

作者： joseph J Alukal Talan Zhang Paul joseph Thuluvath Institute of Digestive Health and Liver Diseases Mercy Medical CenterBaltimoreMD 21202United States Department of Medicine University of Maryland School of MedicineBaltimoreMD 21202United States

The Budd Chiari syndrome(BCS)is a rare and potentially fatal disease,but there is a paucity of data on the in-hospital mortality as well its economic burden on the health care *** To evaluate trends in mortality,length of hospital stays and resource utilization among inpatients with *** Data on all adult patients with a diagnosis of BCS were extracted from the National Inpatient Sample(NIS)from 1998 to *** make inferences regarding the national estimates for the total number of BCS discharges across the study period,sample weights were applied to each admission per recommendations from the *** During the study period,there were 3591(8.73%)in-patient *** overall inhospital mortality rates among BCS patients decreased from 18%in 1998 to 8%in 2017;the mortality decreased by 4.41%(P<0.0001)every *** multivariate analysis,older age,higher comorbidity score,acute liver failure,acute kidney injury,acute respiratory failure,hepatic encephalopathy,hepatorenal syndrome,inferior vena cava thrombosis,intestinal infarct,sepsis/septic shock and cancer were associated increased risk of *** average of length of stay was 8.8 d and it consistently decreased by 2.04%(95%CI:-2.67%,-1.41%,P<0.001)from 12.7 d in 1998 to 7.6 d in *** average total charges after adjusted for Medical Care Consumers Price Index to 2017 dollars during the time period was$94440 and the annual percentage change increased by 1.15%(95%CI:0.35%,1.96%,P=0.005)from$95515 in 1998 to$103850 in *** The in-hospital mortality rate for patients admitted with BCS in the United States has reduced between 1998 and 2017 and this may a reflection of better management of these patients.

关键词： National Inpatient Sample Budd Chiari syndrome Mortality Length of stay Total charges

Commentary regarding “on-orbit sleep problems of astronauts and countermeasures”

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Military Medical Research 2019年第2期6卷 178-182页

作者： joseph John Bevelacqua Seyed Mohammad Javad Mortazavi Bevelacqua Resources 343Adair DriveRichland WA99352USA Department of Electrical Engineering Biophotonics LabUniversityof Wisconsin Milwaukee3200N Cramer StMilwaukee WI53211USA Doss Lab(R-432) Fox Chase Cancer Center333Cottman AvenuePhiladelphia PA19111USA

This commentary addresses the article by Wu et al. entitled 'On-orbit sleep problems of astronauts and countermeasures'. In this article, the authors discussed the sleep problems of astronauts. Despite its challenging topic, the paper authored by Wu et al. has at least one major shortcoming. This issue is related to the observation that the sleep pattern of astronauts can be disturbed by light flash phenomenon. Since the first report by astronaut E.E. Aldrin in 1969, many astronauts have reported light flashes. These visually perceived flashes of light occurred in different shapes but they apparently moved across the visual field of astronauts and possibly caused, at least to some extent, sleep problems. Moreover, the countermeasures proposed by the authors may improve astronauts’ sleep pattern, but they do not address the root cause of the light flashes(i.e., heavy ion interactions outside the shielding provided by the Earth’s magnetosphere). A possible approach to reducing light flashes is available using the fact that much of the galactic cosmic radiation(GCR) spectrum is composed of ions that can be diverted from the spacecraft using electromagnetic fields. Possible design parameters and the requisite electric and magnetic field strengths to successfully deflect GCR radiation are outlined.

关键词： Space radiation Astronauts Sleep problems Light flashes Phosphenes

The second brain in Parkinson’s disease: fact or fantasy?

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Neural Regeneration Research 2022年第8期17卷 1737-1738页

作者： Nehal Yemula Paul Njoku joseph Takyi James Paget University Hospital Lowestoft Road Gorleston-on-SeaGreat YarmouthUK Norfolk and Norwich University Hospital Colney LaneNorwichUK Pinderfields Hospital Aberford WayWakefieldUK

Parkinson’s disease(PD)is a movement disorder characterized by reduced dopamine levels due to degeneration of the substantia *** clinical presentation is underlined by bradykinesia,postural instability,and *** is the second most common neurodegenerative disease worldwide,with a huge monetary *** the United States alone,it is estimated that in 2017,the total economic cost was$51.9 billion,and projected to surpass$79 billion by *** research has been conducted into the pathophysiology and clinical implications of the *** neurodegenerative disorder itself,the entity involving the brain-gut axis has been a fundamental model in understanding the disease *** so than ever in PD,the association between gut health and neurological disease is gaining momentum,with the fascinating idea of influencing neurological health by treating the gut.

关键词： degeneration clinical dopamine

The Special Issue on Hot Dry Rock Resource Exploration and Enhanced Geothermal Engineering Preface

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Acta Geologica Sinica(English Edition) 2021年第6期95卷 I0001-I0004页

作者： XU Tianfu joseph MOORE JIANG Zhenjiao Key Laboratory of Groundwater Resources and Environment Ministry of EducationJilin UniversityChangchun 130021China Civil&Environmental Engineering University of UtahDOE-GTO FORGE ProjectUnited States

Geothermal energy is used worldwide primarily for generating electricity, space heating and spas. The geothermal resources that have been developed, however, produce only a small fraction of the available energy stored in the upper few kilometers of the earth’s crust(Tester et al., 2006). Although heat is present, rocks throughout most of the shallow crust lack the interconnected permeability necessary to form geothermal reservoirs.

关键词： crust shallow reservoirs

Wan-Yee joseph Lau:the promoter of modernization and internationalization of Chinese surgery

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Oncology and Translational Medicine 2024年第1期10卷 1-3页

作者： Wan-Yee joseph Lau Faculty of Medicine The Chinese University of Hong KongHong KongChina

To my knowledge,there have been 3 books[1–3]and 2 book chapters written about me.[4–5]For those who are interested in the details of my life,please refer to these books/book *** title of this article is an English translation of the title of the book I refer to as reference 1,which I find appropriate to describe the role that I play in China.

关键词： please details translation

A novel trajectory-based online controller design approach to fault accommodation in NREL’s 5MW wind turbine systems

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Control Theory and Technology 2014年第2期12卷 122-131页

作者： Tushar JAIN joseph J.YAME Dominique SAUTER Aalto University School of Chemical Technology P. O. Box 16100 F1-00076 Aalto Finland Centre de Recherche en Automatique de Nancy Universite de Lorraine 54506 Vandoeuvre-les-Nancy France

This paper presents a real-time mechanism to tolerate faults occurring in a wind turbine （WT） system. This system is composed of a FAST coded simulator designed by the U.S. National Renewable Energy Laboratory. The demonstrated mechanism lies under the taxonomy of active fault-tolerant control （FTC） systems, namely online redesign based approach. In the proposed approach, we do not use any a priori information about the model of the turbine in real-time. In fact, we use online measurements generated by the WT. Based on the given control specifications, and the observed measurement an occurred fault is accommodated by reconfiguring the online controller such that the WT generates rated power even under faulty conditions. Second, no explicit fault diagnosis （FD） module is used in this approach. As a result, issues of model uncertainty, false alarms, etc. associated with an integrated FD and controller reconfiguration approach to FTC systems are not experienced here.

关键词： Fault-tolerant control Behavioral theory Wind turbines Online controller redesign

A high-throughput framework for determining adsorption energies on solid surfaces

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npj Computational Materials 2017年第1期3卷 357-360页

作者： joseph H.Montoya Kristin A.Persson Lawrence Berkeley National Laboratory 1 Cyclotron RoadBerkeleyCA 94720USA Department of Materials Science and Engineering University of CaliforniaBerkeleyCA 94720USA

In this work,we present a high-throughput workflow for calculation of adsorption energies on solid surfaces using density functional *** open-source computational tools from the Materials Project infrastructure,we automate the procedure of constructing symmetrically distinct adsorbate configurations for arbitrary *** algorithms are further used to construct and run workflows in a standard,automated way such that user intervention in the simulation procedure is *** validate our approach,we compare results from our workflow to previous experimental and theoretical benchmarks from the CE27 database of chemisorption energies on solid *** benchmarks also illustrate how the task of performing and managing over 200 individual density functional theory calculations may be reduced to a single submission procedure and subsequent *** enabling more efficient high-throughput computations of adsorption energies,these tools will accelerate theory-guided discovery of advanced materials for applications in catalysis and surface science.

关键词： theory. adsorption determining

Forage breeding and cultivar development:A 50-year perspective

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Grassland Research 2023年第2期2卷 97-105页

作者： joseph Henry Bouton Institute of Plant Breeding Geneticsand GenomicsUniversity of GeorgiaAthensGeorgiaUSA Bouton Consulting Group LLCAthensGeorgiaUSA

This article represents the perspective of one retired,academic forage breeder and cultivar developer after 50 years of working *** cultivars that help farmers within pastoral agriculture is the main goal,a system where livestock is the *** Grassland Congress proceedings,as well as the general literature,are historical guides for the state of forage *** was achieved through technologies;better equipment for planting and harvesting;and advances in computer computation and *** achievements were fitful and continue to *** performance mean-reversion,cost to the program,and what the farmer seed buyer was willing to pay are important considerations for applying any technology,especially *** promises were too *** was due,in part,to a lack of understanding that traditional phenotypic/genotypic field selection programs operate in a complex way with multiple species and several traits screened simultaneously at a modest *** majority of current forage cultivars are from field-based *** participation at scientific conferences declined over time,with less sharing of information the *** developers will continue using basic field selection methods but should explore applying any technology;just be clever on when,how,and with whom to use *** advice and experiences are also presented and discussed.

关键词： biotechnologies breeding cultivars farmers forages genetics livestock pastures

Assessing farmers' contribution to greenhouse gas emission and the impact of adopting climate-smart agriculture on mitigation

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Ecological Processes 2020年第1期9卷 592-601页

作者： Michael Ayeah Israel joseph Amikuzuno Gideon Danso-Abbeam Department of Agricultural and Resource Economics University for Development StudiesTamaleGhana

Background:The adoption of climate-smart agricultural(CSA)practices is expected to improve farmers’adaptation to climate change and also increase yields while simultaneously curbing greenhouse gas(GHG)*** paper explores the determinants of smallholder farmers’participation in GHG-emitting *** also estimates the impact of CSA activities on reducing GHG ***:The findings are based on survey data obtained from 350 smallholder farmers in the East Gonja district of Northern *** adopted the generalized Poisson regression model in identifying factors influencing farmers’participation in the GHG emission practices and inverse-probability-weighted regression adjustment(IPWRA)to estimate the impact of CSA adoption on GHG ***:Most farming households engaged in at least one emission *** findings of the generalized Poisson model found that wealthier households,higher education,and households with access to extension services were less likely to participate in GHG emission *** was also evidence that CSA adoption significantly reduces GHG ***:Advocacy in CSA adoption could be a necessary condition for environmental protection through the reduction of GHG emissions.

关键词： Climate-smart agriculture Emission Mitigation Adoption Under-dispersion Count models Treatment effect