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Ecological Processes 2024年第1期13卷 188-205页

作者： Michael A.Eggleton cody J.Salzmann joseph E.Kaiser Shannon c.F.Smith Department of Aquaculture and Fisheries University of Arkansas at Pine Bluff Arkansas Game and Fish commission Virginia Institute of Marine Science

Background Since the late 1990s, bigheaded carps(largely silver carp [Hypophthalmichthys molitrix] but also bighead carp [H. nobilis]) have established throughout the lower Mississippi River basin. Using previously studied oxbow lakes in the lower White River basin, Arkansas, we compared current(2017, “post-carp” establishment) fish assemblages to historical(2002, “pre-carp” establishment) fish assemblages. Fish assemblages were comprehensively assessed using multiple gears, including boat electrofishing, mini-fyke nets, and experimental small-mesh gill *** T-tests suggested that fish assemblage indices of richness, diversity, evenness, and dominance were often greater(P carp period as reflected by boat electrofishing and experimental gill nets. However, all indices were generally similar(P > 0.05) between the pre-carp and post-carp period with fish assemblages depicted using mini-fyke nets. Nonmetric multidimensional scaling analyses indicated that fish assemblages differed structurally between pre-carp and post-carp periods. Assemblage differences were linked to both small and large abundance changes for more than 20 species. Abundances of gizzard shad(Dorosoma cepedianum), emerald shiner(Notropis atherinoides), pugnose minnow(Opsopoeodus emiliae), crappies(Pomoxis spp.), bluegill(Lepomis macrochirus), orangespotted sunfish(L. humilis), and yellow bass(Morone mississippiensis) declined between the pre-carp and postcarp periods. conversely, abundances of weed shiner(N. texanus), pallid shiner(Hybopsis amnis), longear sunfish(L. megalotis), buffalofishes(Ictiobus spp.), and gars(Lepisosteus spp.) generally increased during the same *** Although not possible to conclude assemblage shifts were entirely related to bigheaded carps due to the absence of an appropriate reference system where carps did not establish, the wide establishment of these carps is one of the most pervasive changes to have occurred in the lower White

关键词： Bigheaded carp Silver carp Aquatic nuisance species Fish assemblage Oxbow lake Large river

Deformable microlaser force sensing

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Light(Science & Applications) 2024年第6期13卷 1196-1209页

作者： Eleni Dalaka joseph SHill Jonathan H.H.Booth Anna Popczyk Stefan R.Pulver Malte c.Gather Marcel Schubert centre of Biophotonics SUPASchool of Physics and AstronomyUniversity of St AndrewsNorth HaughSt AndrewsUK Humboldt centre for Nano-and Biophotonics Department of ChemistryUniversity of CologneKölnGermany School of Psychology and Neuroscience University of St AndrewsSt Mary’s QuadSouth StreetSt AndrewsUK Institute for Bioengineering of catalonia BarcelonaSpain

Mechanical forces are key regulators of cellular behavior and function,affecting many fundamental biological processes such as cell migration,embryogenesis,immunological responses,and pathological *** force sensors and imaging techniques have been developed to quantify these otherwise invisible forces in single cells and in ***,current techniques rely heavily on high-resolution microscopy and do not allow interrogation of optically dense tissue,reducing their application to 2D cell cultures and highly transparent biological ***,we introduce DEFORM,deformable microlaser force sensing,a spectroscopic technique that detects sub-nanonewton forces with unprecedented spatio-temporal *** is based on the spectral analysis of laser emission from dye-doped oil microdroplets and uses the force-induced lifting of laser mode degeneracy in these droplets to detect nanometer *** validation by atomic force microscopy and development of a model that links changes in laser spectrum to applied force,DEFORM is used to measure forces in 3D and at depths of hundreds of microns within tumor spheroids and late-stage Drosophila *** furthermore show continuous force sensing with single-cell spatial and millisecond temporal resolution,thus paving the way for non-invasive studies of biomechanical forces in advanced stages of embryogenesis,tissue remodeling,and tumor invasion.

关键词： invasion otherwise hundreds

EVOLUTION AND INTERAcTION OFδ-WAVES IN THE ZERO-PRESSURE GAS DYNAMIcS SYSTEM

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Acta Mathematica Scientia 2024年第5期44卷 1801-1836页

作者： Abhishek DAS K.T.joseph centre for Data Science Institute of Technical Education and Research(ITER)Siksha‘O’Anusandhan(Deemed to be University)BhubaneswarOdisha751030India centre for Applicable Mathematics Tata Institute of Fundamental ResearchSharada NagarBangalore560065KarnatakaIndia

Evolution and interaction of plane waves of the multidimensional zero-pressure gas dynamics system leads to the study of the corresponding one dimensional *** this paper,we study the initial value problem for one dimensional zero-pressure gas dynamics *** the first equation is the Burgers equation and the second one is the continuity *** consider the solution with initial data in the space of bounded Borel *** we prove a general existence result in the algebra of generalized functions of *** we study in detail special solutions withδ-measures as initial *** study interaction of waves originating from initial data concentrated on two point sources and interaction with classical shock/rarefaction *** gives an understanding of plane-wave interactions in the multidimensional *** use the vanishing viscosity method in our analysis as this gives the physical solution.

关键词： zero-pressure gas dynamics delta-waves interaction of waves

Treatment of Helicobacter pylori with potassium competitive acid blockers:A systematic review and meta-analysis

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World Journal of Gastroenterology 2024年第9期30卷 1213-1223页

作者： joseph Edwin Kanu Jonathan Soldera Post Graduate Program at Acute Medicine and Gastroenterology University of South WalesCardiff CF371DLUnited Kingdom

BAcKGROUND Helicobacter pylori(***)infects over half the global population,causing gastrointestinal diseases like dyspepsia,gastritis,duodenitis,peptic ulcers,GMALT lymphoma,and gastric *** *** is crucial for treating and preventing these *** conventional proton pump inhibitor(PPI)-based triple therapy is effective,there’s growing interest in longer acid suppression *** competitive acid blocker(P-cAB)triple and dual therapy are new regimens for *** *** used in Asian populations,vonoprazan(VPZ)has been recently Food and Drug Administration-approved for *** *** To assess the efficacy of regimens containing P-cABs in eradicating *** *** This study,following PRISMA 2020 guidelines,conducted a systematic review and meta-analysis by searching MEDLINE and Scopus libraries for randomized clinical trials(RcTs)or observational studies with the following command:[("Helicobacter pylori"OR"H pylori")AND("Treatment"OR"Therapy"OR"Eradication")AND("Vonaprazan"OR"Potassium-competitive Acid Blocker"OR"P-cAB"OR"PcAB"OR"Revaprazan"OR"Linaprazan"OR"Soraprazan"OR"Tegoprazan")].Studies comparing the efficacy of P-cABs-based treatment to classical PPIs in eradicating *** were *** criteria included case reports,case series,unpublished trials,or conference *** variables encompassed age,diagnosis method,sample sizes,study duration,intervention and control,and *** eradication method were gathered by two independent ***-analysis was performed in R software,and forest plots were *** A total of 256 references were initially retrieved through the search ***,fifteen studies(7 RcTs,7 retrospective observational studies,and 1 comparative unique study)were included,comparing P-cAB triple therapy to PPI triple *** intention-to-treat analysis involved 8049 patients,with 4471 in the P-cAB intervention g

关键词： Helicobacter pylori infection Potassium competitive acid blockers Proton pump inhibitors Vonoprazan Amoxicillin

Stability and Time-Step constraints of Implicit-Explicit Runge-Kutta Methods for the Linearized Korteweg-de Vries Equation

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communications on Applied Mathematics and computation 2024年第1期6卷 658-687页

作者： joseph Hunter Zheng Sun Yulong Xing Department of Mathematics The Ohio State UniversityColumbusOH43210USA Department of Mathematics The University of AlabamaTuscaloosaAL35487USA

This paper provides a study on the stability and time-step constraints of solving the linearized Korteweg-de Vries(KdV)equation,using implicit-explicit(IMEX)Runge-Kutta(RK)time integration methods combined with either finite difference(FD)or local discontinuous Galerkin(DG)spatial *** analyze the stability of the fully discrete scheme,on a uniform mesh with periodic boundary conditions,using the Fourier *** the linearized KdV equation,the IMEX schemes are stable under the standard courant-Friedrichs-Lewy(cFL)conditionτ≤λ***,λis the cFL number,τis the time-step size,and h is the spatial mesh *** study several IMEX schemes and characterize their cFL number as a function ofθ=d/h^(2)with d being the dispersion coefficient,which leads to several interesting *** also investigate the asymptotic behaviors of the cFL number for sufficiently refined meshes and derive the necessary conditions for the asymptotic stability of the IMEX-RK *** numerical experiments are provided in the paper to illustrate the performance of IMEX methods under different time-step constraints.

关键词： Linearized Korteweg-de Vries(KdV)equation Implicit-explicit(IMEX)Runge-Kutta(RK)method Stability courant-Friedrichs-Lewy(cFL)condition Finite difference(FD)method Local discontinuous Galerkin(DG)method

Wan-Yee joseph Lau:the promoter of modernization and internationalization of chinese surgery

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Oncology and Translational Medicine 2024年第1期10卷 1-3页

作者： Wan-Yee joseph Lau Faculty of Medicine The Chinese University of Hong KongHong KongChina

To my knowledge,there have been 3 books[1–3]and 2 book chapters written about me.[4–5]For those who are interested in the details of my life,please refer to these books/book *** title of this article is an English translation of the title of the book I refer to as reference 1,which I find appropriate to describe the role that I play in china.

关键词： please details translation

Monogenic diabetes in children:An underdiagnosed and poorly managed clinical dilemma

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World Journal of Diabetes 2024年第6期15卷 1051-1059页

作者： Saptarshi Bhattacharya joseph M Pappachan Department of Endocrinology Indraprastha Apollo HospitalsDelhi 110076India Department of Endocrinology and Metabolism Lancashire Teaching Hospitals NHS TrustPreston PR29HTUnited Kingdom Faculty of Science Manchester Metropolitan UniversityManchester M156BHUnited Kingdom Faculty of Biology Medicine and HealthThe University of ManchesterManchester M139PLUnited Kingdom

Monogenic diabetes,constituting 1%-2%of global diabetes cases,arises from single gene defects with distinctive inheritance *** over 50 associated genetic disorders,accurate diagnoses and management of monogenic diabetes remain inadequate,underscoring insufficient clinician *** disease spectrum encompasses maturity-onset diabetes of the young(MODY),characterized by distinct genetic mutations affecting insulin secretion,and neonatal diabetes mellitus(NDM)-a heterogeneous group of severe hyperglycemic disorders in *** diabetes,autoimmune monogenic diabetes,genetic insulin resistance and lipodystrophy syndromes further diversify the monogenic diabetes landscape.A tailored approach based on phenotypic and biochemical factors to identify candidates for genetic screening is recommended for suspected cases of *** diagnosis warrants immediate molecular genetic testing for infants under six *** these genetic defects presents a unique opportunity for precision *** research aimed to develop cost-effective genetic testing methods and gene-based therapy can facilitate appropriate identification and optimize clinical *** and study of new genes offer a valuable opportunity to gain deeper insights into pancreatic cell biology and the pathogenic mechanisms underlying common forms of *** clinical review published in the recent issue of World Journal of Diabetes is such an attempt to fill-in our knowledge gap about this enigmatic disease.

关键词： Monogenic diabetes Maturity-onset diabetes of the young Neonatal diabetes Mitochondrial diabetes Insulin resistance syndromes Genetic testing Next generation sequencing

Periodontitis:An often-neglected complication of diabetes

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World Journal of Diabetes 2024年第3期15卷 318-325页

作者： Marina G Kudiyirickal joseph M Pappachan Primary care Dental Practice The Smile ClinicPreston PR16PZUnited Kingdom Department of Endocrinology and Metabolism Lancashire Teaching Hospitals NHS TrustPreston PR29HTUnited Kingdom Faculty of Science Manchester Metropolitan UniversityManchester M156BHUnited Kingdom Faculty of Biology Medicine and HealthThe University of ManchesterManchester M139PLUnited Kingdom

The bidirectional association between type 2 diabetes mellitus(T2DM)and periodontitis is now well established,resulting in periodontal disease being considered as the 6th major complication of diabetes mellitus(DM)after cardiovascular disease,eye disease,neuropathy,nephropathy,and peripheral vascular *** can worsen the virulence and invasiveness of pathogenic oral microbial flora aggravating the local inflammation and infection in those with periodontal *** the other hand,the chemical and immunological mediators released into the circulation as part of periodontal inflammation worsen the systemic insulin resistance with worsening of *** if undiagnosed or left untreated can also result in eventual tooth loss.A study by Xu et al in the World Journal of Diabetes examined the predictive factors associated with periodontitis in chinese patients with *** prevalence of periodontitis was found to be 75.7%in this *** on logistic regression analysis,the predictive factors for higher risk were low tooth brushing frequency[odds ratio(OR)=4.3],high triglycerides(TG;OR=3.31),high total cholesterol(Tc;OR=2.87),higher glycated hemoglobin(HbA1c;OR=2.55),and higher age(OR=1.05)while higher education level was protective(OR=0.53).However,the most influential variables were HbA1c followed by age,Tc,TG,low education level,brushing frequency,and sex on the random forest model(this model showed higher sensitivity for predicting the risk).A good understanding of the predictors for periodontitis in T2DM patients is important in prevention,early detection of susceptible patients,and intervention to improve periodontal health and enable long-term glycaemic control as observed by Xu et al.

关键词： Diabetes mellitus Periodontitis Predictive factors cardiovascular disease Glycaemic control

Hemodynamic management of congenital diaphragmatic hernia:the role of targeted neonatal echocardiography

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World Journal of Pediatric Surgery 2024年第2期7卷 81-89页

作者： Aimann Surak Linda Mahgoub joseph Y Ting Department of Pediatrics University of AlbertaEdmontonAlbertaCanada

congenital diaphragmatic hernia(cDH)is a major congenital anomaly,resulting from the herniation of abdominal contents into the thoracic cavity,thereby impeding the proper development of the lungs and pulmonary *** severity correlates with a spectrum of pulmonary hypoplasia,pulmonary hypertension(PHT),and cardiac dysfunction,constituting the pathophysiological triad of this complex *** accurate diagnosis and effective management of PHT and cardiac dysfunction is pivotal to optimizing patient *** neonatal echocardiography is instrumental in delivering real-time data crucial for the bespoke,pathophysiology-targeted hemodynamic management of cDH-associated PHT.

关键词： congenital targeted neonatal