检索结果-南通市图书馆

Origin of high particle number concentrations reaching the St. Louis, Midwest Supersite

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2015年第8期27卷 219-231页

作者： benjamin de Foy James J.Schauer Department of Earth and Atmospheric Sciences Saint Louis University Civil and Environmental Engineering University of Wisconsin

Ultrafine particles are associated with adverse health effects. Total Particle Number Concentration（TNC） of fine particles were measured during 2002 at the St. Louis — Midwest supersite. The time series showed overall low level with frequent large peaks. The time series was analyzed alongside criteria pollutant measurements and meteorological observations. Multiple regression analysis was used to identify further contributing factors and to determine the association of different pollutants with TNC levels. This showed the strong contribution of sulfur dioxide（SO2） and nitrogen oxides（NO x） to high TNC levels. The analysis also suggested that increased dispersion resulting from faster winds and higher mixing heights led to higher TNC levels. Overall, the results show that there were intense particle nucleation events in a SO2 rich plume reaching the site which contributed around 29% of TNC. A further 40% was associated with primary emissions from mobile sources. By separating the remaining TNC by time of day and clear sky conditions,we suggest that most likely 8% of TNC are due to regional nucleation events and 23% are associated with the general urban background.

关键词： Atmospheric aerosols Particle number concentrations Fine particles Sulfur dioxide plumes Mobile source emissions

An investigation of the formulation and nutritional composition of modern meat analogue products

在线全文

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2019年第4期8卷 320-329页

作者： benjamin M.Bohrer Department of Food Science University of Guelph50 Stone Road East GuelphOntarioN1G 2W1Canada

Meat analogues,or plant-based products that simulate the properties of traditional meat products,have secured a position in the conversation of protein *** growth of the meat analogue industry is occurring in the global food marketplace in both the retail and food service *** purpose of this review was to investigate the ingredients used in the formulation of modern meat analogues,evaluate the nutrient specifications of modern meat analogue products,and then form a comparison with traditional meat *** on this investigation,it was determined–firstly,the ingredients used in the formulation of modern meat analogue products make these products fit under the classification of ultra-processed foods;and secondly,the nutrient specifications of popular meat analogue products can effectively simulate the nutrient specifications of the meat products they are attempting to ***,based on these findings,modern meat analogue products can offer roughly the same composition of nutrients as traditional meat products,albeit with many different ingredients and a high level of further processing.

关键词： Plant-based meat Simulated meat Meat alternatives Processed foods Protein foods

Ensuring federated learning reliability for infrastructure-enhanced autonomous driving

在线全文

学校读者我要写书评

暂无评论

Journal of Intelligent and Connected Vehicles

Journal of Intelligent and Connected Vehicles 2023年第3期6卷 125-135页

作者： benjamin Acar Marius Sterling Technical University of Berlin Berlin10623Germany

The application of machine learning techniques,particularly in the context of autonomous driving solutions,has grown exponentially in recent *** such,the collection of high-quality datasets has become a prerequisite for training new ***,concerns about privacy and data usage have led to a growing demand for decentralized methods that can be learned without the need for pre-collected *** learning(FL)offers a potential solution to this problem by enabling individual clients to contribute to the learning process by sending model updates rather than training *** Federated Learning has proven successful in many cases,new challenges have emerged,especially in terms of network availability during *** a global instance is responsible for collecting updates from local clients,there is a risk of network downtime if the global server *** this study,we propose a novel and crucial concept that addresses this issue by adding redundancy to our *** than deploying a single global model,we deploy a multitude of global models and utilize consensus algorithms to synchronize and keep these replicas *** utilizing these replicas,even if the global instance fails,the network remains *** a result,our solution enables the development of reliable Federated Learning systems,particularly in system architectures suitable for infrastructure-enhanced autonomous ***,our findings enable the more effective realization of use cases in the context of cooperative,connected,and automated mobility.

关键词： federated learning(FL) Kubernetes autonomous driving

Fluorine-thiol displacement probes for acetaminophen's hepatotoxicity

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2023年第1期13卷 204-212页

作者： benjamin L.Prather Shuyue Ji Yue Zhao Femil joseph Shajan Mi Zhao Zakey Yusuf Buuh Robert Maloney Rui Zhang Carson Cohen Rongsheng E.Wang Department of Chemistry Temple UniversityPhiladelphiaPA 19122USA

Chemicals possessing reactive electrophiles can denature innate proteins leading to undesired toxicity,and the overdose-induced liver injury by drugs containing electrophiles has been one of the major causes of non-approval and withdraw by the US Food and Drug Administration(FDA).Elucidating the associated proteins could guide the future development of therapeutics to circumvent these drugs’toxicities,but was largely limited by the current probing tools due to the steric hindrance of chemical tags including the common“click chemistry”*** the widely used non-steroidal anti-inflammatory drug acetaminophen(APAP)as an example,we hereby designed and synthesized an APAP analogue using fluorine as a steric-free *** toxicity studies indicated our analogue has similar activity to the parent *** analogue was applied to the mouse hepatocellular proteome together with the corresponding desthiobiotinSH probe for subsequent fluorine-thiol displacement reactions(FTDRs).This set of probes has enabled the labeling and pull-down of hepatocellular target proteins of the APAP metabolite as validated by Western *** preliminary validation results supported the interaction of APAP with the thioredoxin protein,which is an important redox protein for normal liver *** results demonstrated that our probes confer minimal steric perturbation and mimic the compounds of interest,allowing for global profiling of interacting *** fluorine-thiol displacement probing system could emerge as a powerful tool to enable the investigation of drug-protein interactions in complex biological environments.

关键词： Acetaminophen(APAP) Liver Hepatotoxicity Bioorthogonal Click chemistry Fluorinedisplacement Fluorinethiol displacementreaction FTDR

在线全文

学校读者我要写书评

暂无评论

数据物理学家的兴起

世界科学 2024年第8期 53-54页

作者：思羽本杰明·纳赫曼劳伦斯伯克利国家实验室

数据规模进一步扩大，科学教育需要反映这种变化。传统来说，许多物理学家将自己分作两个相互斗争的阵营：理论物理学家和实验物理学家。阿尔伯特·爱因斯坦建立广义相对论，而亚瑟·爱丁顿（Arthur Eddington）观测到广义相对论“弯曲...

数据规模进一步扩大，科学教育需要反映这种变化。传统来说，许多物理学家将自己分作两个相互斗争的阵营：理论物理学家和实验物理学家。阿尔伯特·爱因斯坦建立广义相对论，而亚瑟·爱丁顿（Arthur Eddington）观测到广义相对论“弯曲”星光；默里·盖尔曼（Murray Gell-Mann）和乔治·茨威格（George Zweig）构思出夸克概念，而亨利·肯德尔（Henry Kendall）、理查德·泰勒（Richard Taylor）、杰尔姆·弗里德曼（Jerome Freidman）及他们的团队探测到夸克。

关键词：

Efficacy and tolerability of chitin-glucan combined with simethicone(GASTRAP^(■)DIRECT)in irritable bowel syndrome:A prospective,open-label,multicenter study

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Pharmacology and Therapeutics 2024年第3期15卷 10-22页

作者： Nathalie Talbodec Pauline Le Roy Peggy Fournier Benoit Lesage Elodie Lepoutre François Castex Jean Michel Godchaux Lionel Vandeville benjamin Bismuth Xavier Lesage Pauline Bayart Michael Genin Christel Rousseaux Veronique Maquet Salvatore Modica Pierre Desreumaux Caroline Valibouze Department of Gastroenterology Hôpital privéLe BoisLille 59000France Department of Gastroenterology Hôpital privéde Villeneuve d’AscqVilleneuve d’Ascq 59650France Univ.Lille CHU LilleULR 2694–METRICSÉvaluation des Technologies de Santéet des Pratiques MédicalesLille 59000France Development of Intestinal Biotech 1 Avenue Oscar LambretLille 59045France KitoZyme SA Parc Industriel des hauts Sarts Zone 2Rue de MilmortHerstal 4040Belgium BiOkuris A Parc Industriel des hauts Sarts Zone 2Rue de MilmortHerstal 4040Belgium Department of Hepato-Gastroenterology Lille University HospitalLille 59000France U1286-INFINITE Institute for Translational Research in InflammationUniv.LilleInsermCHU LilleLille 59000France Department of Digestive Surgery and Transplantation Lille University HospitalLille 59037France

BACKGROUND Irritable bowel syndrome(IBS),defined according to the Rome IV diagnostic criteria,is a chronic functional gastrointestinal disorder characterized by recurrent abdominal pain related to altered bowel ***-line recommended treatments are limited to combining drugs targeting predominant symptoms,particularly pain(antispasmodics),constipation(laxatives),and diarrhea(loperamide),yielding only a limited therapeutic ***^(■)DIRECT is a class IIa medical formulation composed of a combination of chitin-glucan and simethicone indicated for the symptomatic treatment of gas-related gastrointestinal disorders by combining different mechanisms of *** To evaluate the efficacy,tolerability,and safety of 4-week GASTRAP^(■)DIRECT treatment in patients with *** In this prospective,multicenter,open-label trial,120 patients with IBS received three sticks of GASTRAP^(■)DIRECT(1.5 g/d of chitin-glucan and 0.75 mg/d of simethicone)per day for 4 *** primary endpoint was the responder rate,defined as the number of patients whose abdominal pain score decreased by≥30%from baseline to week(W)*** analysis was performed using the per-protocol *** symptoms,impact of global symptoms on daily life,change in stool consistency,and improvement in defecatory disorders were *** Overall,100 patients were *** W4,67%(95%CI:57-75)showed improvement in abdominal pain(score:5.8±2.4 vs 2.9±2.0,P<0.0001).Similar improvements were observed for bloating[8.0±1.7 vs 4.7±2.9,P<0.0001;60%(95%CI:50-70)responders],abdominal distension[7.2±2.1 vs 4.4±3.1,P<0.0001;53%(95%CI:43-63)responders],and impact of global symptoms on daily life[7.1±2.0 vs 4.6±2.9,P<0.0001;54%(95%CI:44-64)responders].Stool consistency improved in most patients(90%and 57%for patients with liquid and hard stools,respectively).Overall,42%of patients with defecatory disorders reported very much/considerable improvements by *** severe adverse event occurred,and tolerabil

关键词： Chitin-glucan Irritable bowel syndrome Abdominal pain Flatulence Defecatory disorders Stool consistency Natural non-pharmacological treatment

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

质疑上司要讲究技巧

Once upon a time biomass burning in the western Alps: Nesting effects of climate and local drivers on long-term subalpine fires

商业评论 2024年第5期 170-173页

作者：本杰明·莱克彭建辉雷丁大学亨利商学院

质疑上司不是提高调门这么简单,因为上下有别,涉及权势地位、人际交往和彼此间的尊重.就如同跳一段微妙且复杂的交谊舞,当事人要懂得审时度势,掌握进退分寸和交流技巧.毕竟面对职场环境里的上级领导,讲究的是平衡,需要彼此之间的深入了...

质疑上司不是提高调门这么简单,因为上下有别,涉及权势地位、人际交往和彼此间的尊重.就如同跳一段微妙且复杂的交谊舞,当事人要懂得审时度势,掌握进退分寸和交流技巧.毕竟面对职场环境里的上级领导,讲究的是平衡,需要彼此之间的深入了解和对情势的准确把握.

关键词：

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

Forest Ecosystems 2022年第2期9卷 257-266页

作者： Christopher Carcaillet benjamin Boulley Frederique Carcaillet Univ Lyon Universite Claude Bernard Lyon 1CNRSENTPE(UMR LEHNA)F-69622VilleurbanneFrance Paris Sciences&Lettres University(PSL) Ecole Pratique des Hautes Etudes(EPHE)F-75014ParisFrance NaturCom Chair Universite de MontpellierF-34000MontpellierFrance MARBEC(Universite de Montpellier CNRSIfremerIRD)F-34000MontpellierFrance

Background:The present article questions the relative importance of local-and large-scale processes on the long-term dynamics of fire in the subalpine belt in the western *** study is based on soil charcoal dating and identification,several study sites in contrasting environmental conditions,and sampling of soil charcoal along the elevation gradient of each *** on local differences in biomass combustion,we hypothesize that local-scale or landscape-scale processes have driven the fire history,while combustion homogeneity supports the hypothesis of the importance of large-scale or macro-ecological processes,especially ***:Biomass burning during the Holocene resulted from the nesting effects of climate,land use,and altitude,but was little influenced by slope exposure(north versus south),soil(dryness,pH,depth),and *** mid-Holocene(6500–2700 cal BP)was an important period for climate-driven biomass burning in the subalpine ecosystems of the western Alps,while fires over the last 2500 years appear much more episodic,prompting us to speculate that human activity has played a vital role in their ***:Our working hypothesis that the strength of local drivers should offset the effects of regional climate is not *** homogeneity of the fire regime between sites thus underscores that climate was the main driver during the Holocene of the western ***-term subalpine fires are controlled by climate at the millennial *** conditions matter for little in determining variability at the century *** mid-Holocene was a chief period for climatic biomass burning in the subalpine zone,while fires during the late Holocene appear much more episodic,suggesting that social drivers has exercised key function on their control.

关键词： Biomass burning Subalpine forest Climate Landscape Pedoanthracology Radiocarbon dating Pyrogenic carbon

Sources of dissolved inorganic carbon in rivers from the Changbaishan area, an active volcanic zone in North Eastern China

在线全文

学校读者我要写书评

暂无评论

Acta Geochimica 2017年第3期36卷 410-415页

作者： Xue Bai benjamin Chetelat Yilong Song Institute of Surface-Earth System Science Tianjin University 92 Weijin Road Tianjin 300072 China School of Environmental Engineering Tianjin University 92 Weijin Road Tianjin 300072 China

Major elements and carbon isotopes of dissolved inorganic carbon(DIC)have been measured in the waters of Changbaishan mountain,a volcanic area in northeastern China,between June and September 2016 to decipher the origin of the CO_2 involved in chemical weathering *** variations of major elements ratios measured in water samples can be explained by a change of the chemical composition of the volcanic rocks between the volcanic cone(trachytes)and the basaltic shield as evidenced by the variations in the composition of these ***,DIC results from the neutralization of CO_2 by silicate *** concentrations vary from 0.3 to 2.5 mmol/L and carbon isotopic compositions of DIC measured in rivers vary from-14.2‰to 3.5‰.At a first order,the DIC transported by rivers is derived from the chemical weathering’s consumption of CO_2 with a magmatic origin,enriched in^(13)C(-5%)and biogenic soil CO_2 with lower isotopic *** highest δ^(13)C values likely result from C isotopes fractionation during CO_2 degassing in rivers.A mass balance based on carbon isotopes suggest that the contribution of magmatic CO_2 varied from less than 20%to more than 70%.Uncertainties in this calculation associated with CO_2 degassing in rivers are difficult to quantify,and the consequence of CO_2 degassing would be an overestimation of the contribution of DIC derived from the neutralization of magmatic CO_2 by silicate rocks.

关键词： Carbon isotopes Dissolved inorganic carbon Rivers Chemical weathering Changbaishan Active volcanic zone