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In‑depth proteome characterization of endometrium and extraembryonic membranes during implantation in pig

Journal of Animal Science and Biotechnology 2024年第3期15卷 1027-1055页

作者： maria A.Gil josep m.cambra Heriberto Rodriguez‑martinez Cristina Cuello Inmaculada Parrilla Emilio A.martinez Department of medicine and Animal Surgery International Excellence Campus for Higher Education and Research“Campus Mare Nostrum”University of MurciaMurciaSpain Institute for Biomedical Research of murcia(ImIB-Pascual Parrilla) MurciaSpain Technical University of munich MunichGermany Department of Biomedical&Clinical Sciences(BKV) BKH/Obstetrics&GynaecologyLinkoping UniversityLinkopingSweden

Background Proteome characterization of the porcine endometrium and extraembryonic membranes is important to understand mother-embryo *** this study,the proteome of the endometrium and cho-rioallantoic membrane was characterized in pregnant sows(PS)during early gestation(d 18 and 24 of gestation)and in the endometrium of non-pregnant sows(NPS)during the same days using LC-mS/mS *** UniProtKB database and ClueGO were used to obtain functional Gene Ontology annotations and biological and functional networks,*** Our analysis yielded 3,254 and 3,457 proteins identified in the endometrium of PS and NPS,respectively;of these,1,753 being common while 1,501 and 1,704 were exclusive to PS and NPS,*** addition,we iden-tified 3,968 proteins in the extraembryonic membranes of *** analyses of function revealed some proteins had relevance for the immune system process and biological adhesion in endometrium while the embryonic chorion displayed abundance of proteins related to cell adhesion and cytoskeletal organization,suggesting they dominated the moment of endometrial remodeling,implantation and adhesion of the lining *** are available via Pro-teomeXchange with identifier *** This is the first in-depth proteomic characterization of the endometrium and extraembryonic mem-branes during weeks 3 to 4 of gestation;data that contribute to the molecular understanding of the dynamic environ-ment during this critical period,associated with the majority of pregnancy losses.

关键词： Endometrium Extraembryonic membranes Implantation Pig Proteome

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Dynamic Equivalent modeling for Black-box microgrids Under multi-operating-point by Using LSTm

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 639-648页

作者： Yunlu Li josep m.Guerrero Junyou Yang Yajuan Guan Guiqing ma Jiawei Feng School of Electrical Engineering Shenyang University of TechnologyShenyang 110819China Department of Energy Technology Center for Research on Microgrids(CROM)Aalborg University9220 Aalborg EastDenmark

Since the high penetration of distributed energy sources complicates the dynamics of electrical power systems,accurate dynamic models are indispensable for study on the transient behavior of the microgrid(mG).In some practices,the lack of full detailed information results in failure of dif-ferential equation based dynamic modeling,which leads to a demand for a black-box mG modeling *** is a critical challenge to maintain the effectiveness of the black-box model under a wide operating range and various fault *** this paper,inspired by the mathematical equivalence between the recurrent neural network(RNN)and differential-algebraic equations(DAEs),a dynamic equivalent modeling method,using long short-term memory(LSTm),is presented to tackle this *** first,the modeling equivalence and advantages of our basic idea are ***,modeling procedures,including data preparation and design guidelines,are ***,the proposed method is applied to a multi-microgrid testing system for performance *** results,under various scenarios,reveal that the proposed modeling method has an adequate capability for representing the dynamic behaviors of a black-box mG under grid fault and operating point changing *** Terms-Deep learning,dynamic behavior,dynamic equivalent model,microgrid,neural network.

关键词： Deep learning dynamic behavior dynamic equivalent model microgrid neural network

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Review of Networked microgrid Protection:Architectures,Challenges,Solutions,and Future Trends

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 448-467页

作者： Jorge de la Cruz Ying Wu John E.Candelo-Becerra Juan C.Vasquez josep m.Guerrero Center for Research on microgrids(CROm) Department of Energy TechnologyAalborg University9220 AalborgDenmark Facultad de minas Departamento de Energia Eléctrica y AutomaticaUniversidad Nacional de ColombiaSede MedellinCarrera 80 No.65-223RobledoMedellin 050041Colombia. Center for Research on microgrids at UPC(UPC CROm) Department of Electronic EngineeringTechnical University of Catalonia(UPC)08019 Barcelona Spain ICREA Pg.Lluis Companys 2308010 BarcelonaSpain Center for Research on microgrids at AAU(AAU CROm) AAU EnergyAalborg University(AAU)9220 Aalborg EastDenmark

Design and selection of advanced protection schemes have become essential for reliable and secure operation of networked *** protection schemes that allow correct operation of microgrids have been proposed for individual systems in different topologies and ***,protection schemes for networked microgrids are still in devel-opment,and further research is required to design and operate advanced protection in interconnected *** of these microgrids in different nodes with various intercon-nection technologies increases fault occurrence and complicates protection *** paper aims to point out challenges in developing protection for networked microgrids,potential solutions,and research areas that need to be addressed for their ***,this article presents a systematic analysis of different microgrid clusters proposed since 2016,including several architectures of networked microgrids,operation modes,components,and utilization of renewable sources,which have not been widely explored in previous review ***,the paper presents a discussion on protection systems currently available for microgrid clusters,current challenges,and solutions that have been proposed for these ***,it discusses the trend of protection schemes in networked microgrids and presents some conclusions related to ***—Adaptive eprotection,microgrid cluster,microgrid,multiple microgrid,networked microgrid,real-time simulation,smart grid.

关键词： Adaptive eprotection microgrid cluster microgrid multiple microgrid networked microgrid real-time simulation smart grid

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Improved multiple Feature-electrochemical Thermal Coupling modeling of Lithium-ion Batteries at Low-temperature with Real-time Coefficient Correction

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Protection and Control of modern Power Systems 2024年第3期9卷 157-173页

作者： Shunli Wang Haiying Gao Paul Takyi-Aninakwa josep m.Guerrero Carlos Fernandez Qi Huang IET the School of Electric Power Inner Mongolia University of TechnologyInner Mongolia 010051China the School of Information Engineering Southwest University of Science and TechnologyMianyang 621010China Southwest University of Science and Technology(SWUST) the Smart Energy Storage Institute the Department of Energy Technology Aalborg UniversityDenmark Robert Gordon University IEEE Southwest University of Science and Technology

monitoring various internal parameters plays a core role in ensuring the safety of lithium-ion batteries in power supply *** also influences the sustainability effect and online state of charge *** improved multiple feature-electrochemical thermal coupling modeling method is proposed considering low-temperature performance degradation for the complete characteristic expression of multi-dimensional *** is to obtain the parameter influence mechanism with a multi-variable coupling *** optimized decoupled deviation strategy is constructed for accurate state of charge prediction with real-time correction of time-varying current and temperature *** innovative decoupling method is combined with the functional relationships of state of charge and open-circuit voltage to capture energy management ***,an adaptive equivalent-prediction model is constructed using the state-space equation and iterative feedback correction,making the proposed model adaptive to fractional *** maximum state of charge estimation errors of the proposed method are 4.57% and 0.223% under the Beijing bus dynamic stress test and dynamic stress test conditions,*** improved multiple feature-electrochemical thermal coupling modeling realizes the effective correction of the current and temperature variations with noise influencing coefficient,and provides an efficient state of charge prediction method adaptive to complex conditions.

关键词： Adaptive inner state characterization lithium-ion batteries low-temperature automatic-guided-vehicle multiple feature-electrochemical thermal coupling modeling real-time coefficient correction

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male genitourinary schistosomiasis-related symptoms among long-term Western African migrants in Spain: a prospective population-based screening study

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贫困所致传染病(英文) 2024年第2期13卷 29-38页

作者： Roure Sílvia Vallès Xavier Pérez-Quílez Olga López-mu?oz Israel Chamorro Anna Abad Elena Valerio Lluís Soldevila Laura Espa?a Sergio Hegazy Alaa H. A. Fernández-Rivas Gema Gorriz Ester Herena Dolores Oliveira mário miralles maria Carme Conde Carmen montero-Alia Juan José Fernández-Pedregal Elia miranda-Sánchez Jose Llibre josep m. Isnard mar Bonet josep maria Estrada Oriol Prat Núria Clotet Bonaventura The Schisto-Stop study group Primary Health Care Unit mataró-(Rocafonda-Palau) Barcelona North Metropolitan Health Directorate Catalan Institute for Health Camí Ral el Ravalet Mataró Barcelona Spain Barcelona North metropolitan Primary Care Directorate Catalan Institute for Health Ctra. de Barcelona Sabadell Barcelona Spain Directorate for Innovation and Interdisciplinary Cooperation Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Can Ruti S/N Badalona Spain IrsiCaixa-AIDS Research Institute Hospital Universitari Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Infectious Diseases Directorate Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Can Ruti S/N Badalona Spain International Health Program (PROSICS) Barcelona North Metropolitan Territorial Directorate for Infectious Diseases Catalan Institute for Health CAP La Salut Passatge dels Encants S/N Badalona Spain Fundació Lluita contra les Infeccions c/Can Ruti s/n Badalona Spain Infectious Diseases Department Hospital Universitari Germans Trias i Pujol c/Can Ruti s/n Badalona Spain Germans Trias i Pujol Research Institute c/Can Ruti s/n Badalona Spain microbiology Department Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Department of Genetics and microbiology Universitat Autònoma de Barcelona c/Can Ruti s/n Badalona Spain Faculty of medicine University of Asyut El Fateh Assiut Governorate Egypt Department of Urology Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Canovelles Primary Health Care Unit Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Indústria Canovelles Spain

Background Schistosomiasis is highly endemic in sub-Saharan Africa and frequently imported to Europe. male urogenital manifestations are often neglected. We aimed to ascertain the prevalence of genitourinary clinical signs and symptoms among long-term African migrants in a non-endemic European country using a serology *** We carried out a prospective, community-based cross-sectional study of adult male migrants from sub-Saharan Africa living in *** serology tests and microscopic urine examinations were carried out, and clinical data were obtained from an electronic medical record search and a structured *** We included 388 adult males, mean age 43.5 years [Standard Deviation (SD) = 12.0, range: 18–76]. The median time since migration to the European Union was 17 [Interquartile range (IQR): 11–21] years. The most frequent country of origin was Senegal (N = 179, 46.1%). Of the 338, 147 (37.6%) tested positive forSchistosoma. Parasite eggs were present in the urine of only 1.3%. Nine genitourinary clinical items were significantly associated with positiveSchistosoma serology results: pelvic pain (45.2%;OR = 1.57, 95%CI: 1.0–2.4), pain on ejaculation (14.5%;OR = 1.85, 95%CI: 1.0–3.5), dyspareunia (12.4%;OR = 2.45, 95%CI: 1.2–5.2), erectile dysfunction (9.5%;OR = 3.10, 95%CI: 1.3–7.6), self-reported episodes of infertility (32.1%;OR = 1.69, 95%CI: 1.0–2.8), haematuria (55.2%;OR = 2.37, 95%CI: 1.5–3.6), dysuria (52.1%;OR = 2.01, 95%CI: 1.3–3.1), undiagnosed syndromic STIs (5.4%), and orchitis (20.7%;OR = 1.81, 95%CI: 1.0–3.1). Clinical signs tended to *** Urogenital clinical signs and symptoms are prevalent among male African long-term migrants with a positiveSchistosoma serology results. Genital involvement can be frequent even among those with long periods of non-residence in their sub-Saharan African countries of origin. Further research is needed to develop diagnostic tools and validate therapeutic approaches to

关键词： Schistosomiasis Chronic schistosomiasis Urogenital schistosomiasis male genital schistosomiasis Longterm migrant

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Brain-derived neurotrophic factor signaling in the neuromuscular junction during developmental axonal competition and synapse elimination

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Neural Regeneration Research 2025年第2期20卷 394-401页

作者： josep Tomàs Víctor Cilleros-mañé Laia Just-Borràs marta Balanyà-Segura Aleksandra Polishchuk Laura Nadal marta Tomàs Carolina Silvera-Simón manel m.Santafé maria A.Lanuza Unitat d’Histologia i Neurobiologia(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the development of the nervous system,there is an overproduction of neurons and *** competition between neighboring nerve endings and synapses performing different activity levels leads to their elimination or *** have extensively studied the involvement of the brain-derived neurotrophic factor-Tropomyosin-related kinase B receptor neurotrophic retrograde pathway,at the neuromuscular junction,in the axonal development and synapse elimination process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developmental synapse elimination,in relation to other molecular pathways that we and others have found to regulate this *** particular,we summarize our published results based on transmitter release analysis and axonal counts to show the different involvement of the presynaptic acetylcholine muscarinic autoreceptors,coupled to downstream serine-threonine protein kinases A and C(PKA and PKC)and voltage-gated calcium channels,at different nerve endings in developmental *** dynamic changes that occur simultaneously in several nerve terminals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the mechanisms of specific *** describe an activity-dependent balance(related to the extent of transmitter release)between the presynaptic muscarinic subtypes and the neurotrophin-mediated TrkB/p75NTR pathways that can influence the timing and fate of the competitive interactions between the different axon *** downstream displacement of the PKA/PKC activity ratio to lower values,both in competing nerve terminals and at postsynaptic sites,plays a relevant role in controlling the elimination of supernumerary ***,calcium entry through L-and P/Q-subtypes of voltage-gated calcium channels(both channels are present,together with the N-type channel in developing nerve terminals)contributes to red

关键词： acetylcholine release adenosine receptors axonal competition brain-derived neurotrophic factor calcium channels motor end-plate muscarinic acetylcholine receptors postnatal synapse elimination serine kinases tropomyosin-related kinase receptorB

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Permafrost carbon cycle and its dynamics on the Tibetan Plateau

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Science China Life Sciences 2024年第09期 1833-1848页

作者： Leiyi Chen Guibiao Yang Yuxuan Bai Jinfeng Chang Shuqi Qin Futing Liu mei He Yutong Song Fan Zhang josep Pe?uelas Biao Zhu Guoying Zhou Yuanhe Yang Key Laboratory of Tibetan medicine Research Chinese Academy of Sciences State Key Laboratory of Vegetation and Environmental Change Institute of Botany Chinese Academy of Sciences China National Botanical Garden College of Environmental and Resource Sciences Zhejiang University Key Laboratory of Forest Ecology and Environment of National Forestry and Grassland Administration Ecology and Nature Conservation Institute Chinese Academy of Forestry University of Chinese Academy of Sciences Consejo Superior de Investigaciones Científicas (CSIC) Global Ecology Unit CREAF-CSIC-UAB (Universitat Autònoma de Barcelona) Centre for Ecological Research and Forestry (CREAF) Institute of Ecology College of Urban and Environmental Sciences and Key Laboratory for Earth Surface Processes of the Ministry of Education Peking University Northwest Institute of Plateau Biology Chinese Academy of Sciences

Our knowledge on permafrost carbon(C) cycle is crucial for understanding its feedback to climate warming and developing nature-based solutions for mitigating climate change. To understand the characteristics of permafrost C cycle on the Tibetan Plateau, the largest alpine permafrost region around the world, we summarized recent advances including the stocks and fluxes of permafrost C and their responses to thawing, and depicted permafrost C dynamics within this century. We find that this alpine permafrost region stores approximately 14.1 Pg(1 Pg=1015g) of soil organic C(SOC) in the top 3 m. Both substantial gaseous emissions and lateral C transport occur across this permafrost region. moreover, the mobilization of frozen C is expedited by permafrost thaw, especially by the formation of thermokarst landscapes,which could release significant amounts of C into the atmosphere and surrounding water bodies. This alpine permafrost region nevertheless remains an important C sink, and its capacity to sequester C will continue to increase by 2100. For future perspectives, we would suggest developing long-term in situ observation networks of C stocks and fluxes with improved temporal and spatial coverage, and exploring the mechanisms underlying the response of ecosystem C cycle to permafrost thaw. In addition, it is essential to improve the projection of permafrost C dynamics through in-depth model-data fusion on the Tibetan Plateau.

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喜马拉雅山不同森林群落主要树种叶片元素性状与生物量之间的关系

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中国科学：地球科学 2024年第5期54卷 1544-1555页

作者： Nita DYOLA 梁尔源 josep PEÑUELAS JJulio CAmARERO Shalik Ram SIGDEL Sugam ARYAL 林文涛刘向刘永稳徐兴良 Sergio ROSSI 中国科学院青藏高原研究所青藏高原地球系统与资源环境全国重点实验室北京100101 中国科学院大学北京100049 Laboratoire sur lesécosystèmes terrestres boréaux Département des Sciences FondamentalesUniversitédu QuébecàChicoutimi555Boulevard de l′UniversitéChicoutimi(QC)G7H2B1Canada CSIC Global Ecology Unit CREAF-CSIC-UABBellaterraE-08193 CataloniaSpain CREAF Cerdanyola del VallèsE-08193 CataloniaSpain Instituto Pirenaico de Ecología(IPE-CSIC) Avenida Montañana 1005Zaragoza 50059Spain Friedrich-Alexander-Universität Erlangen-Nürnberg Institut für GeographieErlangen 91058Germany 兰州大学生态学院草种创新与草地农业生态系统全国重点实验室兰州730000 中国科学院地理科学与资源研究所生态系统网络观测与模拟重点实验室北京100101

植物需要多种基本元素调节并保持其特定比例以维持生长发育,叶片元素含量反映了植物的功能及其对环境的适应性.然而,在森林海拔梯度上,我们对于资源获取、光合作用和生长相关的叶片元素如何调节森林生物量仍知之甚少.本研究在喜马拉雅... 详细信息

植物需要多种基本元素调节并保持其特定比例以维持生长发育,叶片元素含量反映了植物的功能及其对环境的适应性.然而,在森林海拔梯度上,我们对于资源获取、光合作用和生长相关的叶片元素如何调节森林生物量仍知之甚少.本研究在喜马拉雅山干城章嘉峰地区沿热带森林(海拔80m)至高山树线(海拔4200m)设置海拔梯度样带,每间隔海拔100m设置一个样点,对116个树种的1859个个体测定了叶片中10种元素(C、N、P、K、Ca、mg、Zn、Fe、Cu和mn)的含量,通过计算叶片元素含量的群落加权平均值(反映优势物种的性状优势度,表征质量比效应)和功能离散度(反映物种在生态位空间内的聚集或者离散程度,表征互补效应),探究叶片元素含量及其离散程度沿海拔梯度分异特征,解析其对森林群落生物量的影响.研究结果表明,较强的叶片元素质量比效应和较弱的互补效应有利于森林群落生物量的积累.叶片元素性状多样性与海拔的共同作用对生物量的解释量(解释方差:52.2%)高于元素性状多样性的解释量(解释方差:0.05%~21%).海拔调节了树种性状多样性在生物量积累中的作用,互补效应在低海拔和高海拔地区对生物量的影响分别体现为积极和消极作用,这表明海拔和互补效应之间也存在交互作用.此外,海拔和质量比效应的交互作用对海拔梯度上生物量的影响也存在异质性.本研究表明,不同森林群落生物量的积累可能受到由海拔调控的性状多样性的影响.尽管较高的性状分异不利于生物量的积累,但能增强高海拔地区树种对胁迫环境的适应性.

关键词：生态系统功能海拔梯度功能多样性功能性状叶片元素生态位互补

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Attack-resilient control for converter-based DC microgrids

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Global Energy Interconnection 2023年第6期6卷 751-757页

作者： Sen Tan Juan C.Vasquez josep m.Guerrero Aalborg University Fredrik Bajers Vej 7KAalborg9220Denmark

In light of the growing integration of renewable energy sources in power systems,the adoption of DC microgrids has become increasingly popular,due to its simple structure,having no frequency,power factor ***,the dependence of DC microgrids on cyber-networks also makes them susceptible to *** cyberattacks can disrupt power system facilities and result in significant economic and loss of *** address this concern,this paper presents an attack-resilient control strategy for microgrids to ensure voltage regulation and power sharing with stable operation under cyber-attack on the *** paper first formulates the cyber-security problem considering a distributed generation based microgrid using the converter model,after which an attack-resilient control is proposed to eliminate the actuator attack impact on the *** state analysis and root locus validation illustrate the feasibility of the proposed *** effectiveness of the proposed control scheme is demonstrated through simulation results.

关键词： Cyber-attacks DC microgrids Resilient control

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Square cavity flow driven by two mutually facing sliding walls

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2023年第7期24卷 612-624页

作者： Bo AN josep m.BERGADà Weimin SANG Dong LI F.mELLIBOVSKY School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China National Key Laboratory of Science and Technology on Aerodynamic Design and Research Xi'an 710072China Key Laboratory of Icing and Anti/De-icing China Aerodynamics Research and Development CenterMianyang 621000China Department of Fluid mechanics Universitat Politécnica de CatalunyaBarcelona 08034Spain Department of Physics Aerospace Engineering DivisionUniversitat Politécnica de CatalunyaBarcelona 08034Spain

We investigate the flow inside a 2D square cavity driven by the motion of two mutually facing walls independently sliding at different *** exploration,which employs the lattice Boltzmann method(LBm),extends on previous studies that had the two lids moving with the exact same speed in opposite *** there,here the flow is governed by two Reynolds numbers(Re_(T),Re_(B))associated to the velocities of the two moving *** convenience,we define a bulk Reynolds number Re and quantify the driving velocity asymmetry by a parameterα.Parameterαhas been defined in the rangeα∈[-π4,0]and a systematic sweep in Reynolds numbers has been undertaken to unfold the transitional dynamics path of the two-sided wall-driven cavity *** particular,the critical Reynolds numbers for Hopf and NeimarkSacker bifurcations have been determined as a function ofα.The eventual advent of chaotic dynamics and the symmetry properties of the intervening solutions are also analyzed and *** study unfolds for the first time the full bifurcation scenario as a function of the two Reynolds numbers,and reveals the different flow topologies found along the transitional path.

关键词： Two-sided wall-driven cavity Velocity ratios Transitions Flow topology Energy cascade

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