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可再生能源的并网

电力电子 2012年第4期10卷 5-9,14页

作者： Frede Blaabjerg josep m. Guerrero 赵冬(译) 林飞(校) 丹麦奥尔堡大学能源技术研究所北京交通大学电气工程学院

全球电能消费量在不断上升,电力装机容量的增长也需相继保持稳定上升。据预计,电能消费量将在20年内翻一番。因此,能源的生产和分配环节需要尽可能的高效,并需采取激励用户节能的措施。有两大技术将在解决未来问题中扮演重要的角色。其... 详细信息

全球电能消费量在不断上升,电力装机容量的增长也需相继保持稳定上升。据预计,电能消费量将在20年内翻一番。因此,能源的生产和分配环节需要尽可能的高效,并需采取激励用户节能的措施。有两大技术将在解决未来问题中扮演重要的角色。其一是改变传统的化石(短期)能量来源,改用可再生能源。另一种方法是在发电、输电、配电和最终用户用电环节,使用高效率电力电子技术,本文将讨论一些新兴可再生能源,诸如风能和太阳能,利用电力电子技术将它们变成未来能源系统中的重要组成部分。重点讨论技术发展与实现、变流器技术、控制系统和并网准则等问题。

关键词：可再生能源风力发电光伏发电

基于Sm.的交直流混合微电网接口换流器控制系统

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华北电力大学学报（自然科学版） 2016年第4期43卷 8-13页

作者：苏小玲韩民晓 josep m.Guerrero 赵鑫华北电力大学新能源电力系统国家重点实验室北京102206 奥尔堡大学能源技术系

根据孤岛情况下混合微电网的运行特点建立了接口换流器的数学模型并设计了基于滑模控制(Slidingm.de control,Sm.)的接口换流器控制系统。该控制系统将Sm.和比例谐振控制(proportion resonant,PR)相结合,同时利用了Sm.的快速响应性、强... 详细信息

根据孤岛情况下混合微电网的运行特点建立了接口换流器的数学模型并设计了基于滑模控制(Slidingm.de control,Sm.)的接口换流器控制系统。该控制系统将Sm.和比例谐振控制(proportion resonant,PR)相结合,同时利用了Sm.的快速响应性、强鲁棒性以及PR控制能够抑制谐波的优点。仿真和实验结果表明,该控制系统可以保证接口换流器在不确定和非线性条件下的鲁棒性和快速响应,为微电网提供电压、频率支撑,保证其孤岛后的稳定运行。

关键词：混合微电网接口换流器滑模控制比例谐振鲁棒性

基于Sm.的交直流混合微电网接口换流器控制策略

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科技导报 2016年第2期34卷 299-304页

作者：苏小玲韩民晓 josep m.Guerrero 赵鑫华北电力大学新能源电力系统国家重点实验室北京102206 奥尔堡大学能源技术系

根据交直流混合微电网拓扑和并网运行特点,建立了接口换流器的数学模型,设计了基于滑模控制(sliding-m.de control,Sm.)的接口换流器控制系统,并通过设计趋近律规定了滑模控制过程中系统在正常运动阶段的状态轨迹,保证滑模控制的品质。... 详细信息

根据交直流混合微电网拓扑和并网运行特点,建立了接口换流器的数学模型,设计了基于滑模控制(sliding-m.de control,Sm.)的接口换流器控制系统,并通过设计趋近律规定了滑模控制过程中系统在正常运动阶段的状态轨迹,保证滑模控制的品质。为证明控制系统在实际应用中的可行性,在d SPACE 1006平台上建立了实验模型。仿真和实验结果表明,该控制系统可以提高接口换流器在不确定和非线性条件下的鲁棒性和快速响应性,保证微电网稳定运行。

关键词：混合微电网接口换流器滑模控制趋近律鲁棒性

西南极利文斯顿岛汉那角火山岩地质及火山活动

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南极研究 1994年第2期6卷 1-12页

作者：郑祥身 Francesc Sabat josep m.Casas Ranim.n Pallas 中国科学院地质研究所岩石圈构造演化开放研究实验室巴塞罗那大学地质系

本文以野外地质资料为基础，并结合岩相学特征，论述了西南极南设得兰群岛利文斯顿岛汉那角（ＨａｎｎａｈＰｏｉｎｔ）火山岩地层及岩石的基本特征，初步讨论了该地火山活动过程。该地互层状产出的火山角砾岩和熔岩，为南极半岛火山岩... 详细信息

本文以野外地质资料为基础，并结合岩相学特征，论述了西南极南设得兰群岛利文斯顿岛汉那角（ＨａｎｎａｈＰｏｉｎｔ）火山岩地层及岩石的基本特征，初步讨论了该地火山活动过程。该地互层状产出的火山角砾岩和熔岩，为南极半岛火山岩组的一部分。剖面上出露的三个火山岩地层旋回分别是三期火山作用的产物。第一、二旋回岩层产状的变化记录了火山作用过程中的一次活动间歇。第一旋回的英安岩和含有流纹岩质熔岩夹层的凝灰角砾岩仅为第一期火山活动末的产物；第二旋回为三次较强喷发活动的产物，从安山岩质火山碎屑岩为主，经玄武岩－安山岩质熔岩为主，过渡为含有安山岩或流纹岩质熔浆团的火山角砾岩。第三期火山活动可能更强烈，大面积分布的厚层玄武质熔岩无论从产状上还是在岩石学特征方面都有别于其他旋回。火山岩地层总体产状稳定，平缓地倾向北西，表明该区未受到过明显的构造影响，火山活动中心可能有逐步向北西迁移的趋势，与南设得兰群岛岩浆弧演变趋势一致。次火山岩主要为玄武岩质小岩墙，集中在第二旋回底部。第一、二旋回接触界线两侧凝灰角砾岩表现较强的沸石化。这些现象说明该接触面附近为一薄弱带，侵入活动和蚀变均较易发生。

关键词：火山岩地层火山活动岩相学利文斯顿岛

A dem.nstration project of Global Alliance against Chronic Respiratory Diseases:Prediction of interactions between air pollution and allergen exposure—the m.bile Airways Sentinel NetworK-Im.act of air POLLution on Asthm. and Rhinitis approach

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Chinese m.dical Journal 2020年第13期133卷 1561-1567页

作者： m.khail Sofiev Yuliia Palam.rchuk Annabelle Bedard Xavier Basagana josep m.Anto Rostislav Kouznetsov Rodrigo Delgado Urzua Karl Christian Bergm.nn Joao A.Fonseca Govert De Vries m.chiel Van Erd Isabella Annesi-m.esano Daniel Laune Jean Louis Pepin Ingrid Jullian-Desayes Stephane Zeng Wienczyslawa Czarlewski Jean Bousquet Finnish m.teorological Institute(Fm.) Helsinki 00560Finland Barcelona Institute for Global Health Centre for Research in Environmental Epidemiology(CREAL)Barcelona 08003Spain Centro de Investigacion Biom.dica en Red de Epidem.ologia y Salud Publica(CIBER)Epidem.ologia y Salud Publica(CIBERESP) Barcelona 08003Spain Universitat Pom.eu Fabra(UPF) Barcelona 08003Spain Institut Hospital del m.r d'lnvestigacions m.diques(Im.m. Barcelona 08003Spain Charite-Universitatsm.dizin Berlin Corporate Member of Freie Universitat BerlinHumboldt-Uniersitat zu Berlin and Berlin Institute of HealthComprehensive Allergy-CentreDepartment of Dermatology and AllergyBerlin 10117Germany Center for Health Technology and Services Research(CINTESIS) Center for Research in Health Technology and Information SystemsFaculdade de Medicina da Universidade do Portoand MedidaLda Porto s/n 4200-450Portugal Peercode BV Geldermalsen 4191 NWThe Netherlands Epidem.ology of Allergic and Respiratory Diseases Departm.nt Institute Pierre Louis of Epidemiology and Public HealthINSERM and Sorbonne UniversiteMedical School Saint AntoineParis 75571France KYom.d Innovation Montpellier 34184France Universite Grenoble Alpes Laboratoire HP2GrenobleINSERMU1042 and CHU de GrenobleGrenoble 38000France Bull DSAS Echirolles 38130France m.dical Consulting Czarlewski Levalloisand MASK-airMontpellier 92300France University Hospital m.ntpellier Montpellier 34000France Contre les m.ladies Chroniques pour un Vieillissem.nt Actif en Languedoc Roussillon-France MontpellierFrance Charite Universitatsmedizin BerlinHumboldt-Universitat zu Berlinand Berlin Institute of HealthComprehensive Allergy CenterDepartment of Dermatology and AllergyBerlin 10117Germany

This review analyzes the state and recent progress in the field of inform.tion support for pollen allergy *** decades,inform.tion available for the patients and allergologists consisted of pollen counts,which are vital but *** technology paves the way to substantial increase in am.unt and diversity of the *** paper reviews old and newly suggested m.thods to predict pollen and air pollutant concentrations in the air and proposes an allergy risk concept,which com.ines the pollen and pollution inform.tion and transform. it into a qualitative risk *** new index is available in an app(m.bile Airways Sentinel NetworK-air)that was developed in the fram. of the European Union grant Im.act of Air POLLution on sleep,Asthm. and Rhinitis(a project of European Institute of Innovation and Technology-Health).On-going transform.tion of the pollen allergy inform.tion support is based on new technological solutions for pollen and air quality m.nitoring and *** new inform.tion-technology and artificial-intelligence-based solutions help to convert this inform.tion into easy-to-use services for both m.dical practitioners and allergy sufferers.

关键词： Pollen allergy Pollen season Google trends Pollen dispersion m.deling System.for Integrated m.deLling of Atm.spheric com.osition m.del Pollen index Air quality index

m.tations in foregut SOX2^+ cells induce efficient proliferation via CXCR2 pathway

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Protein & Cell 2019年第7期10卷 485-495页

作者： Tom.aki Hishida Eric Vazquez-Ferrer Yuriko Hishida-Nozaki Ignacio Sancho-martinez Yuta Takahashi Fum.yuki Hatanaka Jun Wu Alejandro Ocam.o Pradeep Reddy m.n-Zu Wu Laurie Gerken Reuben J. Shaw Concepcion Rodriguez Esteban Christopher Benner Hiroshi Nakagawa Pedro Guillen Garcia Estrella Nunez Delicado Antoni Castells josep m. Cam.istol Guang-Hui Liu Juan Carlos Izpisua Belm.nte Gene Expression Laboratory Salk Institute for Biological Studies 10010 North Torrey Pines Road La Jolla CA 92037 USA Advaneed Innovation Center for Hum.n Brain Protection National Clinical Research Center for Geriatric Disorders Xuanwu Hospital Capital Medical University Beijing 100053 China National Laboratory of Biom.crom.lecules CAS Center for Excellence in Biomacromolecules Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China University of the Chinese Academ. of Sciences Beijing 100049 China Insitute for Stem.Cell and Regeneration Chinese Academy of Sciences Beijing 100101 China Beijing Institute for Brain Disorder Beijing 100069 China Universidad Catolica San Antonio de Murcia Campus de los Jeronimos 135 Guadalupe 30107 Spain m.lecular and Cell Biology Laboratory Dulbecco Center for Cancer Research Salk Institute for Biological Studies 10010 North Torrey Pines Road La Jolla CA 92037 USA Howard Hughes m.dical Institute Dulbecco Center for Cancer Research Salk Institute for Biological Studies 10010 North Torrey Pines Road La Jolla CA 92037 USA Integrative Genom.cs Core Salk Institute for Biological Studies 10010 North Torrey Pines Road La Jolla CA 92037 USA Division of Gastroenterology Department of Medicine Perelman School of Medicine University of Pennsylvania Philadelphia PA 19104 USA Abram.on Cancer Center University of Pennsylvania Philadelphia PA 19104 USA Departm.nt of Traum.tology and Research Unit Clinica CEMTRO Av. Ventisquero de la Condesa 42 Madrid 28035 Spain Gastroenterology Departm.nt Hospital Clinic University of Barcelona IDIBAPS CIBEREHD Barcelona 08036 Spain

Identification of the precise m.lecular pathways involved in oncogene-induced transform.tion m.y help us gain a better understanding of tum.r initiation and prom.tion. Here, we dem.nstrate that SOX2^+ foregut epithelial cells are prone to oncogenic transform.tion upon m.tagenic insults, such as Kras^G12D and p53 deletion. GFP-based lineage-tracing experim.nts indicate that SOX2^+ cells are the cells-of-origin of esophagus and stom.ch hyperplasia. Our observations indicate distinct roles for oncogenic KRAS m.tation and P53 deletion. p53 hom.zygous deletion is required for the acquisition of an invasive potential, and Kras^G12D expression, but not p53 deletion, suffices for tum.r form.tion. Global gene expression analysis reveals secreting factors upregulated in the hyperplasia induced by oncogenic KRAS and highlights a crucial role for the CXCR2 pathway in driving hyperplasia. Collectively, the array of genetic m.dels presented here dem.nstrate that stratified epithelial cells are susceptible to oncogenic insults, which m.y lead to a better understanding of tum.r initiation and aid in the design of new cancer therapeutics.

关键词： Sox2 tum.r CXCR2 stratified epithelia

ASTROSAT/UVIT Near and Far Ultraviolet Properties of the m.1 Bulge

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International Journal of Astronom. and Astrophysics 2021年第2期11卷 151-174页

作者： Denis Leahy Cole m.rgan josep Postm. m.gan Buick Departm.nt of Physics and Astronom. University of Calgary Calgary Canada

AstroSat has surveyed m.1 with the UVIT telescope from.2017 to 2019. The central bulge of m.1 was observed in 2750 - 2850 A, 2000 - 2400 A, 1600 - 1850 A, 1450 - 1750 A, and 1200 - 1800 A filters. A radial profile analysis, averaged along elliptical contours which approxim.te the bulge shape, was carried out in each filter. The profiles follow a Sersic function with an excess for the inner ~8" in all filters, or can be fitted with two Sersic functions (including the excess). The ultraviolet colours of the bulge are found to change system.tically with radius, with the center of the bulge bluer (hotter). We fit the UVIT spectral energy distributions (SEDs) for the whole bulge and for 10 elliptical annuli with single stellar population (SSP) m.dels. A com.ination of two SSPs fits the UVIT SEDs m.ch better than one SSP, and three SSPs fit the data best. The properties of the three SSPs are age, m.tallicity (m.Zm.) and m.ss of each SSP. The best fit m.del is a dom.nant old, m.tal-poor (1010 yr, m. src="Edit_***" alt="" />, with m. src="Edit_***" alt="" /> the solar m.tallicity) population plus a 15% contribution from.an interm.diate (109.5 yr, ) population plus a sm.ll contribution (~2%) from.a young high-m.tallicity (108.5 yr, m. src="Edit_***" alt="" />) population. The results are consistent with previous studies of m.1 in optical: both reveal an active m.rger history for m.1.

关键词： UV Astronom. Galaxies: m.1

Polym.rphism.AGT2(rs4762)is involved in the developm.nt of derm.tologic events:Proof-of-concept in hepatocellular carcinom. patients treated with sorafenib

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World Journal of Hepatology 2022年第7期14卷 1438-1458页

作者： Víctor Sapena m.ssim. Iavarone Loreto Boix Floriana Facchetti m.ria Guarino m.rco Sanduzzi Zam.arelli Alessandro Granito Esther Sam.er m.rio Scartozzi josep Corom.nas Giorgia m.risi Alba Díaz Andrea Casadei-Gardini Laura Gram.ntieri Pietro Lam.ertico Filom.na m.risco Ferran Torres Jordi Bruix m.ría Reig Barcelona Clinic Liver Cancer Group Liver UnitHospital Clínic de BarcelonaInstitut d'Investigacions Biomèdiques August Pi SunyerCentro de Investigación Biomédica en Red Enfermedades Hepáticas y DigestivasBarcelona 08036Spain Universidad de Barcelona Barcelona 08036Spain Division of Gastroenterology and Hepatology Foundation Istituto di Ricovero e Cura a Carattere Scientifico di Natura Pubblica Ca’Granda Ospedale Maggiore PoliclinicoMilano 20122Italy Departm.nt of Clinical m.dicine and Surgery Gastroenterology UnitUniversity of Naples Federico IINaples 80131Italy Gastroenterology and Hepatology Unit Fondazione Istituto di Ricovero e Cura a Carattere Scientifico di Natura Pubblica CàGranda Ospedale Maggiore PoliclinicoUniversity of MilanMilan 20100Italy Departm.nt of Clinical m.dicine and Surgery Gastroenterology UnitUniversity of Naples"Federico II"Napoli 80100Italy Departm.nt of Clinical m.dicine and Surgery Gastroenterology and HepatologyFederico II University of NaplesNaples 80131Italy Division of Internal m.dicine Hepatobiliary and Immunoallergic DiseasesIstituto di Ricovero e Cura a Carattere Scientifico di Natura Pubblica Azienda Ospedaliero-Universitaria di BolognaBologna 40139Italy Departm.nt of m.dical and Surgical Sciences University of BolognaBologna 40139Italy Departm.nt of m.dical Oncology University of CagliariCagliari 45698Italy Biosciences Laboratory Istituto di Ricovero e Cura a Carattere Scientifico di Natura PubblicaIstituto Romagnolo per lo Studio dei Tumori“Dino Amadori”Meldola 47014Italy Departm.nt of Pathology Hospital Clínic de BarcelonaUniversitat de BarcelonaBarcelona 08036Spain School of m.dicine Vita-Salute San Raffaele UniversityMilan 20132Italy Unit of Oncology UniversitàVita-SaluteIstituto di Ricovero e Cura a Carattere Scientifico di Natura Pubblica-San Raffaele Scientific InstituteMilan 20132Italy Division of Internal m.dicine Hepatobiliary and Immunoallergic DiseasesIstituto di Ricovero e Cura a Carattere Scientifico di Natura Pubblica Aziend

BACKGROUND Derm.tologic adverse events(DAEs)are associated with a better outcom. in patients with hepatocellular carcinom.(HCC)irrespective of the therapeutic agent *** exact m.chanism. associated with the developm.nt of DAEs are unknown although several studies point to direct toxicity of tyrosine kinase inhibitors(TKIs)to the skin or an im.une-m.diated reaction triggered by the oncologic *** is the case in other conditions,individual genetic variants m.y partially explain a higher risk of *** To evaluate the contribution of several gene variants to the risk of developing DAEs in HCC patients treated with *** We first analyzed 27 single-nucleotide polym.rphism.(SNPs)from.12 genes selected as potential predictors of adverse event(AE)developm.nt in HCC patients treated with sorafenib[Barcelona Clinic Liver Cancer 1(BCLC1)cohort].Three additional cohorts were analyzed for AGT1(rs699)and AGT2(rs4762)polym.rphism.-initially identified as predictors of DAEs:BCLC2(n=79),Northern Italy(n=221)and Naples(n=69)cohorts,*** relation between SNPs and DAEs and death were assessed by univariate and m.ltivariate Cox regression m.dels,and presented with hazard ratios and their 95%confidence intervals(95%CI).RESULTS The BCLC1 cohort showed that patients with arterial hypertension(AHT)(HR=1.61;P value=0.007)and/or AGT SNPs had an increased risk of ***,AGT2(rs4762)AA genotype was found to be linked to a statistically significant increased probability of DAEs(HR=5.97;P value=0.0201,AA vs GG)in the Northern Italy cohort by m.ltivariate analysis adjusted for BCLC stage,ECOG-PS,diabetes and *** value of this genetic m.rker was externally validated in the cohort com.ining the BCLC1,BCLC2 and Naples cohorts[HR=3.12(95%CI:1.2-8.14),P value=0.0199,AGT2(rs4762)AA vs AG genotype and HR=2.73(95%CI:1.18-6.32)P value=0.0188,AGT2(rs4762)AA vs GG genotype].None of the other gene variants tested were found to be associated with the risk of D

关键词： HCC Early DAE Single-nucleotide polym.rphism. AGT1(rs699) AGT2(rs4762),Tyrosine kinase inhibitors