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MULTIOBJECTIVE ROUTING IN MULTISERVICE MPLS NETWORKS WITH TRAFFIC SPLITTING-A NETWORK FLOW APPROACH

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Journal of Systems Science and Systems Engineering 2015年第4期24卷 389-432页

作者： Rita Girao-Silva jose Craveirinha joao Climaco M.Eugenia Captivo Department of Electrical and Computer Engineering University of Coimbra Polo ⅡPinhal de Marrocos P-3030-290 Coimbra Portugal Institute of Computers and Systems Engineering of Coimbra(INESC-Coimbra)R.Antero de Quental 199 P-3000-033 Coimbra Portugal Centro de Investigacao Operacional Faculdade de CienciasUniversidade de Lisboa Campo GrandeBloco C6Piso 4 P-1749-016 Lisboa Portugal

A multiobjective routing model for Multiprotocol Label Switching networks with multiple service types and traffic splitting is presented in this paper. The routing problem is formulated as a multiobjective mixed-integer program, where the considered objectives are the minimization of the bandwidth routing cost and the minimization of the load cost in the network links with a constraint on the maximal splitting of traffic trunks. Two different exact methods are developed for solving the formulated problem, one based on the classical constraint method and another based on a modified constraint method. A very extensive experimental study, with results on network performance measures in various reference test networks and in randomly generated networks, is also presented and its results are discussed.

关键词： Routing models multiobjective optimization telecommunication networks network flowapproach traffic splitting

Smoothing GNSS Time Series with Asymmetric Simple Moving Averages

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Journal of Civil Engineering and Architecture 2012年第6期6卷 745-750页

作者： jose Nuno Lima joao Casaca National Laboratory of Civil Engineering Lisbon Portugal

There is an increasing trend to apply GNSS continuous observation of short baselines to the monitoring of engineering works, such as bridges and dams, for their structural analysis and safety control. In the case of large dams, one important application of the GNSS continuous observation is thc establishment of early warning systems that demand accurate, frequently updated information and where the analysis of the baseline time series, in order to separate signal from noise is mandatory. The paper presents a study on the performance of linear filters of the asymmetric moving average type to smooth baseline time series. The transfer function of the filter is adopted as a smoothing criterion to choose an adequate order for the moving average, in face of the spectral density function of the baseline time series. Onc series of measurements of a short test baseline （325 m）, materialized in the campus of the National Laboratory for Civil Engineering, is used as an example of the proposed strategy.

关键词： GNSS moving averages spectral density.

Investigation of Galactic open cluster remnants： the case of NGC 7193

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Research in Astronomy and Astrophysics 2017年第1期17卷 31-54页

作者： Mateus de Souza Angelo joao Francisco Coelho dos Santos Jr Wagner jose Barbosa Corradi Francisco Ferreira de Souza Maia Andres Eduardo Piatti Departamento de Fisica ICEx Universidade Federal de Minas Gerais Av. Antonio Carlos 6627 31270-901 Belo Horizonte MG Brazil Observatorio Astronomico Universidad Nacional de Cordoba Laprida 854 5000 Cordoba Argentina Consejo Nacional de Investigaciones Cientificas y Tecnicas Av. Rivadavia 1917 C1033AAJ Buenos AiresArgentina

Galactic open clusters （OCs） that survive the early gas-expulsion phase are gradually de- stroyed over time by the action of disruptive dynamical processes. Their final evolutionary stages are characterized by a poorly populated concentration of stars called an open cluster remnant （OCR）. This study is devoted to assessing the real physical nature of the OCR candidate NGC 7193. GMOS/Gemini spectroscopy of 53 stars in the inner target region were obtained to derive radial velocities and at- mospheric parameters. We also employed photometric and proper motion data. The analysis method consists of the following steps：（i） analysis of the statistical resemblance between the cluster and a set of field samples with respect to the sequences defined in color-magnitude diagrams （CMDs）; （ii） a 5-dimensional iterative exclusion routine was employed to identify outliers from kinematical and posi- tional data; （iii） isochrone fitting to thes× （J - Ks） CMD of the remaining stars and the dispersion of spectral types along empirical sequences in the （J - H） × （H - Ks） diagram were checked. A group of stars was identified for which the mean heliocentric distance is compatible with that obtained via isochrone fitting and whose metallicities are compatible with each other. Fifteen of the member stars observed spectroscopically were identified together with another 19 probable members. Our results indi- cate that NGC 7193 is a genuine OCR, of a once very populous OC, for which the following parameters were derived： d = 501±46 pc, t = 2.5±1.2 Gyr, （[Fe/H]） = -0.17±0.23 and E（B-V） = 0.05±0.05. Its luminosity and mass functions show depletion of low mass stars, confirming the OCR is in a dynam- ically evolved state.

关键词： open cluster remnants - Galactic open clusters

Unlocking the in vitro anti-Trypanosoma cruzi activity of halophyte plants from the southern Portugal

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Asian Pacific Journal of Tropical Medicine 2016年第8期9卷 714-719页

作者： Marta Oliveira Policarpo Ademar Sales Junior Maria joao Rodrigues Marina DellaGreca Luisa Barreira Silvane Maria Fonseca Murta Alvaro jose Romanha Luisa Custodio Center of Marine Sciences (CCMAR) University of AlgarveCampus de Gambelas 8005-139 FaroPortugal Centro de Pesquisas Rene Rachou FIOCRUZ Belo HorizonteMinas GeraisBrazil Dipartimento di Chimica Organica e Biochimica Universita` Federico Ⅱ Complesso Universitario Monte Sant'AngeloVia Cintia 4I-80126NapoliItaly

Objective:To evaluate the in vitro anti-Trypanosoma cruzi（***） activity of organic extracts prepared from halophyte species collected in the southern coast of Portugal（Algarve）,and chemically characterize the most active ***:Acetone,dichloromethane and methanol extracts were prepared from 31 halophyte species and tested in vitro against trypomastigotes and intracellular amastigotes of the Tulahuen strain of *** most active extract was fractionated by preparative HPLC-DAD,affording 11 *** most selective fraction was fully characterized by ***:From 94 samples tested,one was active,namely the root dichloromethane extract of Juncus acutus(IC50 < 20 μg/mL).This extract was fractionated by HPLC,affording 11 fractions,one of them containing only a pure compound（juncunol）,and tested for anti-parasitic *** 8(IC50 = 4.1 μg/mL) was the most active,and was further characterized by *** major compounds were phenanthrenes,9,10-dihydrophenanthrenes and ***:Our results suggest that the compounds identified in fraction 8 are likely responsible for the observed anti parasitic *** research is in progress aiming to isolate and identify the specific active *** the best of our knowledge,this is the first report on the in vitro anti *** activity of halophyte species.

关键词： Chagas disease Halophytes Trypanosoma cruzi Phenanthrenes Juncunol

Recycling and Transmutation of Spent Fuel as a Sustainable Option for the Nuclear Energy Development

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Journal of Energy and Power Engineering 2014年第9期8卷 1505-1510页

作者： jose Rubens Maiorino joao Manoel Losada Moreira Center of Engineering Modeling and Applied Social Sciences Federal University of ABC Santo AndrO 09210-580 Brazil

The objective of this paper is to discuss the option of recycling and transmutation of radioactive waste against once-through fuel cycle based on uranium feed under the perspective of sustainability. A qualitative analysis was carried out to compare the fuel cycles considering different options for burning and recycling transuranic and fission products utilizing accelerator driven systems, fast reactors, and light water reactors. The results show that recycling and transmutation fuel cycles are more attractive than the current once-through fuel cycles from the point of view of sustainability. The main conclusion is that the decision about the construction of deep geological repositories for spent fuel disposal must be reevaluated.

关键词： Recycling transmutation spent fuel sustainability nuclear energy.

The Behavior of Zeta Potential of Silica Suspensions

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New Journal of Glass and Ceramics 2014年第2期4卷 29-37页

作者： jose Antonio Alves Junior joao Baptista Baldo Departamento de Materiais Universidade Federal de Sao CarlosSao CarlosBrazil

Zeta potential is one of the most relevant parameters controlling the rheological behavior of ceramic suspensions. In this work, it was observed that for pH values below the isoelectric point (IEP), the positive value of zeta potential of water suspensions of α-quartz and α-cristobalite, experiences a sudden steep increase with the increase in specific surface area of the powders. For pH values above the IEP, the zeta potential values of crystalline forms of silica (α-quartz and α-cristobalite), get gradually more negative with the increase in pH. Conversely in the case of vitreous silica, for pH values above 6, there occurs a steep change towards more negative values of zeta potential than those presented by quartz and cristobalite. These findings have not yet been accounted for in the DLVO theory but may provide subsidies for better understanding of how to stabilize and destabilize crystalline and vitreous silica water suspensions.

关键词： Silica Slurries Zeta Potential Stabilization Iso-Electronic Point Silica

Failure of Semi-infinite Beams of Variable Thickness and Curvature on Elastic Foundation under Contact Loading

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Journal of Civil Engineering and Architecture 2013年第2期7卷 174-184页

作者： joao Batista De Aguiar jose Manoel De Aguiar Department of Engenharia AeroEspaeial Universidade Federal do ABC Santo Andre 09210-170 Brazil Department of Ensino Geral Faculdade de Teenologia de Sao Paulo Sao Paulo 01124-060 Brazil

In early winter it is usual, in cold regions, that ice features approach offshore structures, like offshore platforms, impacting them, in a slow process of constant deformation build up. Interaction follows, in many cases, up to the point where ice-failure caused by bending fracture takes place. This supposes very large contact forces that the structure has to resist. Therefore, quantification of these efforts is of vital importance to the structural design of platforms. In several designs, these platforms are constructed with inclined walls so as to cause ice to fail in a flex-compression mode. In such a case the ice feature is analyzed as a beam constituted of a linear elastic material in brittle state with constant ice thickness. The simplification renders the problem solvable in a close form. However, this hypothesis goes against field observations. Marine currents action, wind and the sequence of contacts among features lead to thickness variations. Here this factor is addressed in the construction of a model, for harmonic forms of variation of thickness profile, and the accompanying curvature variations, whose solution determines field variables used to address the failure question. Due to the deformation dependency of the loading, a numerical scheme for the two-point boundary value problem in the semi-infinite space is developed. Failure pressures are computed based on a Rankine locus of failure. Variations of the order of 20% in the failure loads, as compared to the uniform beam model, are observed.

关键词： Ice beams thickness variation elastic behavior frictional contact bending failure loads.

Ammonia Sensing System Based on Wavelength Modulation Spectroscopy

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Photonic Sensors 2015年第2期5卷 109-115页

作者： Duarte VIVEIROS joao FERREIRA Susana O. SILVA Joana RIBEIRO Deolinda FLORES jose L. SANTOS Orlando FRAZAO jose M. BAPTISTA INESC Porto Rua do Campo Alegre 687 4169-007 Porto Portugal Geology Center of the University of Porto and Department of Geosciences Environment and Spatial Plannings Facultyof Science at University of Porto Rua do Campo Alegre 687 4169-007 Porto Portugal Department of Physics and Astronomy Faculty of Science at University of Porto Rua do Campo Alegre 687 4169-007 Porto Portugal Competence Center of Exact Sciences and Engineering University of Madeira Campus da Penteada 9000-390 Funchal Portugal

A sensing system in the near infrared region has been developed for ammonia sensing based on the wavelength modulation spectroscopy （WMS） principle. The WMS is a rather sensitive technique for detecting atomic/molecular species, presenting the advantage that it can be used in the near-infrared region by using the optical telecommunications technology. In this technique, the laser wavelength and intensity were modulated by applying a sine wave signal through the injection current, which allowed the shift of the detection bandwidth to higher frequencies where laser intensity noise was typically lower. Two multi-pass cells based on free space light propagation with 160 cm and 16 cm of optical path length were used, allowing the redundancy operation and technology validation. This system used a diode laser with an emission wavelength at 1512.21nm, where NH3 has a strong absorption line. The control of the NH3 gas sensing system, as well as acquisition, processing and data presentation was performed.

关键词： Ammonia sensing fiber optic system near infrared region wavelength modulation spectroscopy,environment

Current status and future perspectives of radiomics in hepatocellular carcinoma

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World Journal of Gastroenterology 2023年第1期29卷 43-60页

作者： joao Miranda Natally Horvat Gilton Marques Fonseca jose de Arimateia Batista Araujo-Filho Maria ClaraFernandes Charlotte Charbel Jayasree Chakraborty Fabricio Ferreira Coelho Cesar Higa Nomura Paulo Herman Department of Radiology University of Sao PauloSao Paulo 05403-010Brazil Department of Radiology Memorial Sloan-Kettering Cancer CenterNew YorkNY 10065United States Department of Gastroenterology University of Sao PauloSao Paulo 05403-000Brazil Department of Radiology Hospital Sirio-LibanesSao Paulo 01308-050Brazil Department of Surgery Memorial Sloan-Kettering Cancer CenterNew YorkNY 10065United States Department of Radiology University of Sao PauloSao Paulo 05403-000Brazil

Given the frequent co-existence of an aggressive tumor and underlying chronic liver disease,the management of hepatocellular carcinoma(HCC)patients requires experienced multidisciplinary team ***,imaging plays a key role in the diagnosis,staging,restaging,and surveillance of ***,imaging assessment of HCC entails the assessment of qualitative characteristics which are prone to inter-reader *** is an emerging field that extracts high-dimensional mineable quantitative features that cannot be assessed visually with the naked eye from medical *** main potential applications of radiomic models in HCC are to predict histology,response to treatment,genetic signature,recurrence,and *** the encouraging results to date,there are challenges and limitations that need to be overcome before radiomics implementation in clinical *** purpose of this article is to review the main concepts and challenges pertaining to radiomics,and to review recent studies and potential applications of radiomics in HCC.

关键词： Radiomics Hepatocellular carcinoma Texture analysis Radiology