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Cognitive Impairment in Alzheimer’s Disease: Longitudinal Data from Brazilian Elderly

Advances in Aging Research 2014年第2期3卷 172-176页

作者： Daniel Bartholomeu Juliana Francisca Cecato jose Eduardo Martinelli jose maria montiel FIEO University Center OsascoBrazil Jundiai Medical School Sao PauloBrazil

Research on cognitive aging is becoming increasingly common because aging is a global phenomenon and brings with it many challenges, for example, the increased incidence of dementias such as Alzheimer’s Disease (AD). Even if the cognitive decline in AD is apparently linear, impairment of autonomy in activities of daily living does not follow the same pattern. Objectives: To monitor and evaluate the cognitive aspects of elderly diagnosed with Alzheimer’s disease. Methodological procedures: This research was conducted from January 2006 to July 2013 at the Clinic of Geriatrics and Gerontology. Longitudinal study of 51 elderly patients aged 60 years, of both sexes who received a diagnosis of Alzheimer’s disease by DSM-IV (APA, 1994) and NINDS-ADRDA (McKhann et al., 2011). Results: From the results obtained in the present study, we observed that the participants had a decline in cognitive function from the first to the second assessment, even with drug treatment.

关键词： Alzheimer Disease Neuropsychiatric Evaluation Cognition Learning

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Impact of socioeconomic and health-related factors on consumption of homeopathic and natural remedies in Spain in 2006, 2011 and 2017

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Journal of Integrative Medicine 2022年第1期20卷 52-56页

作者： jose Antonio Castilla-Jimena Isabel Ruiz-Perez Jesus Henares-montiel Andalusian School of Public Health 1801J GranadaSpain Unit of Clinical Management of Preventive Medicine and Public Health and Occupational Medicine Puerto del Mar University Hospital11009 CadizSpain Consortium for Networked Biomedical Research in Epidemiology and Public Health 28029 MadridSpain Institute for Biosanitary Research(ibs.GRANADA) 18012 GranadaSpain

Objective: Complementary and alternative medicine use and type of use may be influenced by sociodemographic and economic determinants through which we could identify characteristics of patients with greater trend to use it. This paper aims to describe the changes in the consumption of homeopathic and natural remedies in Spain for three time points in order to discern changes in rate of consumption, associated factors and whether their use has been affected by a period of economic ***: This study utilized 2006, 2011 and 2017 cross-sectional data from the Spanish National Health Survey, a nationally representative survey of the population aged more than 15 years old and resident in Spain. Independent bivariate and multivariate descriptive analyses for each of the 3 years studied were ***: The rate of consumption of both homeopathic and natural remedies has decreased over the periods studied. In spite of this decrease, the consumer profile appears to remain stable over the three periods. The sociodemographic factors associated with their consumption were being female, being 30–64 years old, being separated/divorced, having higher education qualifications, being employed and belonging to a higher social class. Psychiatric morbidity, chronic health problems such as pain, mental health problems or malignant tumors, and absence of major cardiovascular events were the clinical factors ***: It can be concluded that beyond the economic situation, the use of homeopathic and natural remedies obeys to the needs of the patients related to their state of health and the response they receive from the health system. It may be that women have different needs and expectations of the healthcare system and, given this breach of expectations, seek remedy to alleviate their needs outside the system and conventional medicine.

关键词： Complementary and alternative medicine Homeopathic remedies Natural remedies Economic recession Gender differences

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阿德里亚——西班牙萨布罗自然湿地中心

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建筑技艺 2009年第11期15卷 90-95页

作者： jose maria Garcia del Monte Ana maria montiel Jimenez

关于这个项目我们有四个出发点：一处令人惊讶的场所：从前是一块邻近城市的自然湿地，人们把水排走欲将其变成一块农田；然而去年它竟恢复到最初的状态。

关键词：自然湿地西班牙德里场所

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Betaglycan（the TGF-βtype Ⅲ receptor） ectodmain is composed of two independent domains required for high affinity TGF-β binding

Betaglycan（the TGF-βtype Ⅲ receptor） ectodmain is compos...

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21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology

作者： Fernando Lopez-Casilias Valentin Mendoza jose Luis montiel Andrew P.Hinck. Universidad Nacional Autonoma de Mexico Universidad Autonoma del Estado de Morelos University of Texas Health Science Center at San Antonio

＜正＞Betaglycan,a membrane proteoglycan,is a co-receptor for diverse members of the TGF-beta *** potentiates TGF-beta effects;however,in its soluble form is a pharmacological useful TGF-beta’inhibitor,Membrane betag...

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Testosterone Levels and Development of the Penile Spines and Testicular Tissue during the Postnatal Growth in Wistar Rats

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Advances in Sexual Medicine 2013年第3期3卷 1-9页

作者： Marcela Arteaga Silva Rosa M.Vigueras Villasenor Socorro Retana Marquez Marisela Hernandez Gonzalez Herlinda Bonilla Jaime Xochitl Guzman García jose Luis Contreras montiel Department of Biology of Reproduction Metropolitan Autonomous UniversityIztapalapaMexico Laboratory of Reproductive Biology National Institute of PediatricsMexico CityMexico Institute of Neuroscience University of GuadalajaraJaliscoMexico Department of Hydrobiology Metropolitan Autonomous UniversityIztapalapaMexico

Aim of Study: Gonadal hormones exert a profound influence on the development, structure and function of the sexual organs. The testosterone is one of the androgens that plays an essential role in the development of sexual organs in male mammals. Therefore, the present study was undertaken to evaluate the testosterone levels and developmental pattern of the penile spines and seminiferous tubules during early postnatal life of Wistar rats. Methods and Materials: At 7, 14, 21, 28, 35, 42, 49, 56, 63 and 70 days after birth, penile and testicular tissues of male rats were dissected out and fixed for histological study and plasma testosterone levels were determined using high resolution chromatography. Results: An increase in the number of penile follicles, primarily in the distal region of the penis, was observed from postnatal days 14 to 42, followed by a gradual decrease. Penile spines were absent from birth until the first growth peak, which was observed at 42 postnatal days. Both testicular weight and the area of seminiferous tubules showed gradual increases before achieving their highest values at 42 postnatal days. Similarly, a gradual increase in testosterone levels was detected from day 28, with a peak at 42 postnatal days. Conclusions: These data show a temporal association between the development of the penile spines and testicular tissue with gradual increases in testosterone levels. These results may contribute to a better understanding of the behavioral, hormonal and morphological changes underlying sexual maturation in male rats.

关键词： Testosterone Penile Spines Testicular Tissue Postnatal Growth Male Rat

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