检索结果-南通市图书馆

What is the ef.ect of.Tr.bulus ter.estr.s on testicular.mor.hology and sper. pr.duction?An exper.mental study in the r.t model

在线全文

学校读者我要写书评

暂无评论

Asian Jour.al of.Andr.logy 2024年第1期26卷 67-70页

作者： Mar.ello Henr.que Ar.ujo Da Silva Gabr.ela f.r.a Buys-Goncalves Joao Henr.que Duque r.is Estr.da f.ancisco jose Bar.ellos Sampaio diogo Benchimol de Souza Ur.genital r.sear.h Unit Rio de Janeiro State UniversityRio de Janeiro 20551-030RJBrazil

The objective of.this study was to investigate whether.tr.atment with Tr.bulus ter.estr.s(Tt)has any impact on the testicular.mor.hology and f.nction in a r.dent *** male r.ts wer. divided into a contr.l gr.up and a gr.up r.ceiving 100 mg kg^(-1) body weight of.Tt *** 4o days of.exper.ment,the animals wer. submitted to euthanasia;epididymal tail sper.atozoa wer. collected;and sper.atozoa concentr.tion,motility,and viability wer. *** addition,testicles wer. collected and pr.cessed f.r.histomor.hometr.cal *** wer. compar.d using the Student's t-test and consider.d signif.cant when Pr.tion,motility,and viability showed no dif.er.nce between the ***,testicular.weight and volume,seminif.r.us tubule diameter.tunica pr.pr.a sur.0}ce density,seminif.r.us epithelium sur.0}ce density,and inter.ubular.compar.ment sur.0}ce density wer. statistically similar.between the ***,seminif.r.us epithelium height and tubular.lumen sur.0}ce density wer. augmented in animals tr.ated with *** with Tt does not cause a major.impact on testicular.mor.hology,pr.moting only subtle *** dif.er.nce on sper.atozoa par.meter. was obser.ed.

关键词： mor.hometr. testicle Tr.bulus ter.estr.s

Cost Compar.sion of.Air.lane Par.ing Methods at Apr.n of.Maptuto Inter.ational Air.or.

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Jour.al of.Southwest Jiaotong Univer.ity(English Edition) 2007年第1期15卷 40-44页

作者： jose f.r.diogo 张华 School of.Civil Engineer.ng Southwest Jiaotong UniversityChengdu 610031 China School of.Civil Engineer.ng Southwest Jiaotong University Chengdu 610031 China

Thr.e known designs f.r.par.ing, f.ontal, angled and par.llel, wer. pr.sented. Air.r.f.s at apr.ns can be par.ed either.by towing equipment （push-back） or.by its own power.（ser.0}power.d par.ing）. The costs of.these two methods f.r.Maputo Inter.ational Air.or. wer. investigated. Based on air.lane par.ing design theor., f.r.ulas to calculate the annual maintenance cost at apr.ns wer. pr.posed. Calculation r.sults indicate that self.power.d par.ing is pr.f.r.ble, justif.ed by the f.ct that this air.or. has low tr.f.ic volume. The system of.air.r.f. par.ing adopted by this air.or. saves signif.cantly the cost f.r.pur.hase and subsequent maintenance of.push-back.

关键词： Air.lane par.ing Push-back equipment Self.power.d par.ing

Novel ther.peutic str.tegies tar.eting mitochondr.a as a gateway in neur.degener.tion

在线全文

学校读者我要写书评

暂无评论

Neur.l r.gener.tion r.sear.h 2023年第5期18卷 991-995页

作者： diogo Tr.go jose Joao Vitor.a Odete A.B.da Cr.z e Silva Neur.science and Signalling Labor.tor. Institute of Biomedicine(iBiMED)Department of Medical SciencesUniversity of AveiroAveiroPortugal

In r.cent year., multiple disciplines have f.cused on mitochondr.al biology and contr.buted to under.tanding its r.levance towar.s adult-onset neur.degener.tive disor.er.. These ar. complex dynamic or.anelles that have a var.ety of.f.nctions in ensur.ng cellular.health and homeostasis. The plethor. of.mitochondr.al f.nctionalities conf.r. them an intr.nsic susceptibility to inter.al and exter.al str.ssor.(such as mutation accumulation or.envir.nmental toxins), par.icular.y so in long-lived postmitotic cells such as neur.ns. Thus, it is r.asonable to postulate an involvement of.mitochondr.a in aging-associated neur.logical disor.er., notably neur.degener.tive pathologies including Alzheimer.s disease and Par.inson’s disease. On the other.hand, biological ef.ects r.sulting f.om neur.degener.tion can in tur. af.ect mitochondr.al health and f.nction, pr.moting a f.edback loop f.r.her.contr.buting to the pr.gr.ssion of.neur.nal dysf.nction and cellular.death. This r.view examines state-of.the-ar. knowledge, f.cus on cur.ent r.sear.h explor.ng mitochondr.al health as a contr.buting f.ctor.to neur.r.gener.tion, and the development of.ther.peutic appr.aches aimed at r.stor.ng mitochondr.al homeostasis in a pathological setting.

关键词： Alzheimer.s disease axon ener.y homeostasis glymphatic system mitochondr.a mitostasis neur.degener.tion neur.r.gener.tion Par.inson’s disease ther.peutical str.tegies

Autor.gr.ssive spatial analysis and individual tr.e modeling as str.tegies f.r.the management of.Er.manthus er.thr.pappus

在线全文

学校读者我要写书评

暂无评论

Jour.al of.f.r.str. r.sear.h 2016年第3期27卷 595-603页

作者： Henr.que f.r.aco Scolf.r. jose r.ber.o Soar.s Scolf.r. jose Mar.io de Mello Anto nio Car.os f.r.az f.lho diogo f.ancisco r.ssoni Thiza f.lqueto Altoe Antonio Donizette Oliveir. r.nato r.beir. de Lima Depar.ment of.f.r.st Science Federal University of Lavras PO Box: 3037 Lavras MG 37200-000 Brazil Depar.ment of.Statistics State University of Maringa Av. Colombo 5.790 Jd. Universitario Bloco E90 Maringa PR 87020-900 Brazil Depar.ment of.Statistics Federal University of Lavras PO Box: 3037 Lavras MG 37200-000 Brazil

The objectives of.this study wer. to apply statistical techniques to discr.minate f.r.ilization tr.atments of.Er.manthus er.thr.pappus（DC.） Mac *** autor.gr.ssive modeling, and to develop individual tr.e models f.r.diameter.and cr.wn ar.a（CA） pr.jection to def.ne management str.tegies f.r.candeia plantations subjected to dif.er.nt f.r.ilization tr.atments. This is an impor.ant tr.e species or.ginating f.om the Br.zilian Atlantic r.in f.r.st and Savannah biomes, intensively used in the cosmetic industr.. Nonetheless, to date, r.sear.h has not addr.ssed the management of.natur.l stands or.plantations of.the species. Our.exper.ment was located in Baependi, Minas Ger.is, Br.zil, and compr.sed of.f.ur.r.ndomized blocks and 13 tr.atments. The tr.atments consisted of.12 dif.er.nt r.gimes of.f.r.ilization plus a contr.l. Each sample plot was composed of.50 plants plus two bor.er.plants in a planting spacing of.2.5 9 2.0 m and under.oing pr.ning at 5 and 6 year. of.age. Star.ing in the second year. total tr.e height（H） and cir.umf.r.nce（at 1.30 m f.om the gr.und or.br.ast height, CBH） wer. measur.d ever. 6 months. Star.ing in the f.f.h year.CA was measur.d. Tr.e gr.wth var.ed by f.r.ilization *** wer. detected by using an autor.gr.ssive appr.ach, consider.ng that standar. statistical methods wer. not power.0}l enough to detect signif.cant *** gr.wth gr.ups wer. f.r.ed, and maximum gr.wth was obtained f.r.tr.atment 10（NPK, 8-28-16）. Management guidelines ar. pr.vided based on individual tr.e models f.r.dif.er.nt f.r.ilization levels.

关键词： Management str.tegies Candeia f.r.ilization level Br.zil Cr.wn ar.a

r.calcitr.nt cell wall of.Ulva lactuca seaweed is degr.ded by a single ulvan lyase f.om f.mily 25 of.polysacchar.de lyases

在线全文

学校读者我要写书评

暂无评论

Animal Nutr.tion 2022年第2期9卷 184-192页

作者： Monica M.Costa Luís B.Pio Pedr. Bule Vania A.Car.oso Mar.ene Duar.e Cr.stina M.Alf.ia diogo f.Coelho Joana A.Br.s Car.os M.G.A.f.ntes jose A.M.Pr.tes CIISA-Centr. de Investigaçao Inter.isciplinar.em Sanidade Animal Faculdade de Medicina Veterinari1Universidade de Lisbo1Alto da Ajud11300-477 Lisbo1Portugal NZYTech-Genes and Enzymes Estrada do Paço do LumiarCampus do LumiarEdifício E1649-038 Lisbo1Portugal

Gr.en macr.algae,e.g.,Ulva lactuca,ar. valuable bioactive sour.es of.nutr.ents;but algae r.calcitr.nt cell walls,composed of.a complex cr.ss-linked matr.x of.polysacchar.des,can compr.mise their.utilization as f.edstuf.s f.r.monogastr.c *** study aimed to evaluate the ability of.pr.-selected Car.ohydr.te-Active enZymes(CAZymes)and sulf.tases to degr.de *** cell walls and r.lease nutr.tive compounds.A databank of.199 r.combinant CAZymes and sulf.tases was tested in vitr. f.r.their.action towar.s *** cell wall *** enzymes wer. incubated with the macr.alga,either.alone or.in combination,to r.lease r.ducing sugar. and decr.ase f.uor.scence intensity of.Calcof.uor.White stained cell *** individual action of.a polysacchar.de lyase f.mily 25(PL25),an ulvan lyase,was shown to be the most ef.icient in cell wall *** ulvan lyase tr.atment,in tr.plicate measur.s,pr.moted the r.lease of.4.54 g/L(Pr.ducing sugar.,a mono-and oligosacchar.des r.lease of.11.4 and 11.2 mmol/100 g of.dr.ed alga(Pr.spectively,and a decr.ase of.41.7%(Pf.uor.scence,in compar.son to *** ability of.ulvan lyase tr.atment to pr.mote the r.lease of.nutr.tional compounds f.om alga biomass was also evaluated.A r.lease of.some monounsatur.ted f.tty acids was obser.ed,par.icular.y the health benef.cial 18:1c9(Pr.no signif.cant r.lease of.total f.tty acids(P>0.05),pr.teins(P?0.861)or.pigments(P>0.05)was *** r.sults highlight the capacity of.a single r.combinant ulvan lyase(PL25 f.mily)to incompletely disr.pt *** cell *** enzyme could enhance the bioaccessibility of.*** bioactive pr.ducts with pr.mising utilization in the f.ed industr..

关键词： Macr.alga Ulva lactuca Car.ohydr.te-active enzyme Ulvan lyase Cell wall degr.dation

在线全文

学校读者我要写书评

暂无评论

中国与莫桑比克典型路面结构对比分析研究

中外公路 2009年第4期29卷 58-62页

作者：张泉陆阳 jose f.ancisco r.f.no diogo 西南交通大学土木工程学院四川成都610031

中国与南部非洲地区自然环境、气候条件、地形地貌差异较大,但路面结构设计方法却相同。作为比较,笔者以莫桑比克路面设计为例,利用弹性层状体系计算程序分别对两国典型路面结构的路表弯沉、沥青层底的拉应变和土基顶的压应变三大指标... 详细信息

中国与南部非洲地区自然环境、气候条件、地形地貌差异较大,但路面结构设计方法却相同。作为比较,笔者以莫桑比克路面设计为例,利用弹性层状体系计算程序分别对两国典型路面结构的路表弯沉、沥青层底的拉应变和土基顶的压应变三大指标进行计算分析,发现对于干燥地区中、轻交通道路,中国的沥青路面结构形式更有利于结构疲劳寿命的增加,保证路面结构的长寿命;对于潮湿的地区,探讨了半刚性路面存在的一些问题,提出了改进的结构形式。

关键词：沥青路面典型路面结构对比分析力学分析法典型结构法

Discogenic pain: Who car.s?

在线全文

学校读者我要写书评

暂无评论

Health 2013年第11期5卷 1929-1937页

作者： jose Pedr. Lavr.dor.Nuno Simas Edson Oliveir. Joaquim Cr.z Teixeir. diogo Simao Ser.io Livr.ghi Neur.sur.ical Depar.ment Hospital Santa MariaLisbonPortugal

Chr.nic low back pain has a huge impact on daily living and a negative economic and pr.f.ssional ef.ect. It is a matter.of.debate and concer. f.r.all health pr.f.ssionals involved, par.icular.y spine sur.eons. r.cent discover.es on the inner.ation and biochemical pr.per.ies of.the inter.er.ebr.l disc clar.f. the r.le of.this str.ctur. as a possible cause of.chr.nic low back pain. However. multiple causes may be pr.sent in the same patient making the diagnosis a challenging pr.cess. Discogenic pain is def.ned as a chr.nic low back pain induced by a degener.tive disc disease. Ther. ar. no specif.c char.cter.stics of.discogenic pain, although it has a higher.incidence in younger.age, it is usually localized medially in the back, wor.ens with axial loading and impr.ves with r.cumbence. In the last decades we have assisted the emer.ence of.multiple tr.atment techniques. However. neither.the conser.ative tr.atment nor.the inter.entional management has str.ng evidence in tr.ating discogenic pain. r.ndomized contr.l clinical tr.als ar. sought to impr.ve patient outcome. Meanwhile, we believe each patient should be appr.ached on an individual base. Discogenic pain: we car..

关键词： Discogenic Pain Low Back Pain Inter.er.ebr.l Disc

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

莫桑比克沥青路面设计介绍

中外公路 2007年第6期27卷 28-30页

作者：牟瀚林陆阳 jose f.ancisco r.f.no diogo 西南交通大学四川成都610031

沥青混凝土因其具有初始投资低、易于维修和循环使用等优点,广泛应用于世界各地,在南非和莫桑比克的路面结构中也得到广泛采用。文章介绍了莫桑比克使用的沥青混凝土设计方法(基于SATCC方法),以期与国内设计方法进行对比研究。

关键词：奠桑比克沥青路面设计结构设计

Per.r.l endoscopic myotomy vs lapar.scopic myotomy and par.ial f.ndoplication f.r.esophageal achalasia: A single-center.r.ndomized contr.lled tr.al

在线全文

学校读者我要写书评

暂无评论

Wor.d Jour.al of.Gastr.enter.logy 2022年第33期28卷 4875-4889页

作者： Eduar.o Tur.ani Hour.eaux de Mour. jose Jukemur. Igor.Br.ga r.beir. Galileu f.r.eir. Ayala f.r.as Aur.o Augusto de Almeida Delgado Lar. Meir.les Azer.do Coutinho diogo Tur.ani Hour.eaux de Mour. r.bens Antonio Aissar.Sallum Ar. Nasi Ser.io A Sanchez-Luna Paulo Sakai Eduar.o Guimar.es Hour.eaux de Mour. Depar.amento de Gastr.enter.logia Faculdade de MedicinaUniversidade de Sao PauloServico de Endoscopia Gastrointestinal do Hospital das Clinicas HCFMUSPSao Paulo 05403-010Brazil Division of.Esophageal Sur.er. Hospital das ClinicasUniversity of Sao Paulo School of MedicineSao Paulo 05403-010Brazil Depar.amento de Gastr.enter.logia Faculdade de MedicinaUniversidade de Sao PauloHospital das ClinicasUniversity of Sao Paulo School of MedicineSao Paulo 05403-010Brazil Depar.ment of.Inter.al Medicine The University of Alabama at Birmingham Heersink School of MedicineBasil I.Hirschowitz Endoscopic Center of ExcellenceDivision of Gastroenterology and HepatologyBirminghamAL 35233United States

BACKGr.UND Achalasia is a r.r. benign esophageal motor.disor.er.char.cter.zed by incomplete r.laxation of.the lower.esophageal sphincter.LES). The tr.atment of.achalasia is not cur.tive, but r.ther.is aimed at r.ducing LES pr.ssur.. In patients who have f.iled noninvasive ther.py, sur.er. should be consider.d. Myotomy with par.ial f.ndoplication has been consider.d the f.r.t-line tr.atment f.r.non-advanced achalasia. r.cently, per.r.l endoscopic myotomy(POEM), a technique that employs the pr.nciples of.submucosal endoscopy to per.0}r. the equivalent of.a sur.ical myotomy,has emer.ed as a pr.mising minimally invasive technique f.r.the management of.this *** To compar. POEM and lapar.scopic myotomy and par.ial f.ndoplication(LM-Pf. r.gar.ing their.ef.icacy and outcomes f.r.the tr.atment of.*** f.r.y tr.atment-naive adult patients who had been diagnosed with achalasia based on clinical and manometr.c cr.ter.a(dysphagia scor. ≥ II and Eckar.t scor. > 3) wer. r.ndomized to under.o either.LM-Pf.or.POEM. The outcome measur.s wer. anesthesia time, pr.cedur. time, symptom impr.vement, r.f.ux esophagitis(as deter.ined with the Gastr.esophageal r.f.ux Disease Questionnair.), bar.um column height at 1 and 5 min(on a bar.um esophagogr.m), pr.ssur. at the LES, the occur.ence of.adver.e events(AEs), length of.stay(LOS), and quality of.lif.(QoL).r.SULTS Ther. wer. no statistically signif.cant dif.er.nces between the LM-Pf.and POEM gr.ups r.gar.ing symptom impr.vement at 1, 6, and 12 mo of.f.llow-up(P = 0.192, P = 0.242, and P = 0.242, r.spectively). However. the r.tes of.r.f.ux esophagitis at 1, 6, and 12 mo of.f.llow-up wer. signif.cantly higher.in the POEM gr.up(P = 0.014, P r.spectively). Ther. wer. also no statistical dif.er.nces r.gar.ing the manometr. values, the occur.ence of.AEs, or.LOS. Anesthesia time and pr.cedur. time wer. signif.cantly shor.er.in the POEM gr.up than in the LM-Pf.gr.up(185.00 ± 56.89 and 95.70 ± 30.47 min v

关键词： Esophageal achalasia Gastr.esophageal r.f.ux Deglutition disor.er. Heller.myotomy f.ndoplication r.ndomized contr.lled tr.al