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Tailored optical propulsion forces for controlled transport of resonant gold nanoparticles and associated thermal convective fluid flows

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Light(Science & Applications) 2020年第1期9卷 256-266页

作者： jose A.Rodrigo Mercedes Angulo Tatiana Alieva Facultad de Ciencias Fisicas Ciudad Universitaria s/nUniversidad Complutense de Madrid28040 MadridSpain

Noble metal nanoparticles illuminated at their plasmonic resonance wavelength turn into heat *** phenomenon has prompted the development of numerous applications in science and *** optical manipulation of such resonant nanoparticles could certainly extend the functionality and potential applications of optothermal *** this article,we experimentally demonstrate optical transport of single and multiple resonant nanoparticles(colloidal gold spheres of radius 200 nm)directed by tailored transverse phase-gradient forces propelling them around a 2D optical *** show how the phase-gradient force can be designed to efficiently change the speed of the *** have found that multiple hot nanoparticles assemble in the form of a quasi-stable group whose motion around the laser trap is also controlled by such optical propulsion *** assembly experiences a significant increase in the local temperature,which creates an optothermal convective fluid flow dragging tracer particles into the ***,the created assembly is a moving heat source controlled by the propulsion force,enabling indirect control of fluid flows as a micro-optofluidic *** existence of these flows,probably caused by the temperature-induced Marangoni effect at the liquid water/superheated water interface,is confirmed by tracking free tracer particles migrating towards the *** propose a straightforward method to control the assembly size,and therefore its temperature,by using a nonuniform optical propelling force that induces the splitting or merging of the group of *** envision further development of microscale optofluidic tools based on these achievements.

关键词： thermal fluid transport

Nonlinear parabolic predator-prey coupled system with convection

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International Journal of Biomathematics 2021年第2期14卷 83-118页

作者： jose Luis Diaz Palencia Mariano Fernandez Lopez University Foundation San Pablo CEU Spain

The aim of this work is to provide a formulation of two related nonlinear diffusive convective models in the form of coupled reaction-absorption ***,the postulated models are studied with an analytical *** on,numerical evidences are considered to account for a precise *** problem(P)analyzed is of the form:ut=δΔu+c⋅∇u+v^(n),vt=ϵΔv+c⋅∇v−um,n,m∈(0,1),u_(0)(x),v_(0)(x)>0∈L^(1)_(loc)(RN)∩L^(∞)(R^(N)).(0.1)Afterwards,a related problem P_(T)is studied:ut=δΔu+c⋅∇u−v^(n)(u−d),vt=ϵΔv+c⋅∇v−u^(m)v,n,m∈(0,1),u_(0)(x),v_(0)(x)>0∈L^(1)_(loc)(R^(N))∩L^(∞)(R^(N)).(0.2)The principal aspects for analysis are related to the existence and the derivation of particular solutions to reproduce the dynamic of the interacting *** the problem PT,we make use of the TW approach to study existence of solutions and precise evolution of *** that the term predator is used to refer to an invasive behavior,while the term prey is used for the invaded species.

关键词： Nonlinearity reaction absorption coupled system diffusion,traveling waves

A Family of Methods of the DG-Morley Type for Polyharmonic Equations

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Advances in Applied Mathematics and Mechanics 2010年第3期2卷 303-332页

作者： Vitoriano Ruas jose Henrique Carneiro De Araujo UPMC-Univ.Paris 6 UMR7190 Inst.Jean Le Rond d’Alembert/CNRSParisFrance Visiting Professor at Graduate School of Computer ScienceUniversidade Federal FluminenseNiteròiRJBrazil Department and Graduate School of Computer Science Universidade Federal FluminenseNiteròiRJBrazil

Discontinuous Galerkin methods as a solution technique of second order elliptic problems,have been increasingly exploited by several authors in the past ten *** is generally claimed the alledged attractive geometrical flexibility of these methods,although they involve considerable increase of computational effort,as compared to continuous *** work is aimed at proposing a combination of DGM and non-conforming finite element methods to solve elliptic m-harmonic equations in a bounded domain of R^(n),for n=2 or n=3,with m≥n+1,as a valid and reasonable alternative to classical finite elements,or even to boundary element methods.

关键词： Discontinuous Galerkin finite elements Hermite tetrahedrons Morley triangle non-conforming polyharmonic equations

Pleiotropy within gene variants associated with nonalcoholic fatty liver disease and traits of the hematopoietic system

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World Journal of Gastroenterology 2021年第4期27卷 305-320页

作者： Carlos jose Pirola Adrian Salatino Silvia Sookoian Department of Molecular Genetics and Biology of Complex Diseases National Scientific and Technical Research Council(CONICET)University of Buenos AiresInstitute of Medical Research(IDIM)Ciudad Autónoma de Buenos Aires C1427AROArgentina Institute of Medical Research A Lanari University of Buenos AiresSchool of MedicineCiudad Autónoma de Buenos AiresCiudad Autónoma de Buenos Aires C1427AROArgentina Department of Clinical and Molecular Hepatology National Scientific and Technical Research Council(CONICET)University of Buenos AiresInstitute of Medical Research(IDIM)Ciudad Autónoma de Buenos Aires C1427AROArgentina

Genome-wide association studies of complex diseases,including nonalcoholic fatty liver disease(NAFLD),have demonstrated that a large number of variants are implicated in the susceptibility of multiple traits—a phenomenon known as pleiotropy that is increasingly being explored through phenome-wide association *** focused on the analysis of pleiotropy within variants associated with hematologic traits and *** used information retrieved from large public National Health and Nutrition Examination Surveys,Genome-wide association studies,and phenome-wide association studies based on the general population and explored whether variants associated with NAFLD also present associations with blood cell-related ***,we applied systems biology approaches to assess the potential biological connection/s between genes that predispose affected individuals to NAFLD and nonalcoholic steatohepatitis,and genes that modulate hematological-related traits—specifically platelet *** reasoned that this analysis would allow the identification of potential molecular mediators that link NAFLD with *** associated with platelet count are most highly expressed in the liver,followed by the pancreas,heart,and ***,genes associated with NAFLD presented high expression levels in the brain,lung,spleen,and *** mapping,gene prioritization,and functional analysis of the most significant loci(P<1×10-8)revealed that loci involved in the genetic modulation of platelet count presented significant enrichment in metabolic and energy balance *** conclusion,variants in genes influencing NAFLD exhibit pleiotropic associations with hematologic traits,particularly platelet ***,significant enrichment of related genes with variants influencing platelet traits was noted in metabolic-related ***,this approach yields novel mechanistic insights into NAFLD pathogenesis.

关键词： Nonalcoholic fatty liver disease Nonalcoholic steatohepatitis Platelets Leukocytes Hematologic traits Genetics

A Semi-Lagrangian Deterministic Solver for the Semiconductor Boltzmann-Poisson System

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Communications in Computational Physics 2007年第5期2卷 1027-1054页

作者： jose A.Carrillo Armando Majorana Francesco Vecil ICREA(Instituci´o Catalana de Recerca i Estudis Avan¸cats)and Departament de Matem`atiques Universitat Aut`onoma de BarcelonaE-08193 BellaterraSpain Dipartimento di Matematica e Informatica Universit`a di CataniaCataniaItaly. Departament de Matem`atiques Universitat Aut`onoma de BarcelonaE-08193 BellaterraSpain.

In this paper we develop a deterministic numerical method for solving the Boltzmann transport equation for semiconductors based on a transport-collision timesplitting *** phases are solved by means of accurate flux-balance methods while collision steps are computed in the original *** experiments are shown allowing for a discussion of this method with respect to other present in the literature.

关键词： Kinetic equations for semiconductors semi-Lagrangian schemes splitting schemes.

A Finite-Volume Method for Nonlinear Nonlocal Equations with a Gradient Flow Structure

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Communications in Computational Physics 2015年第1期17卷 233-258页

作者： jose A.Carrillo Alina Chertock Yanghong Huang Department of Mathematics Imperial College LondonLondon SW72AZUK Department of Mathematics North Carolina State UniversityRaleighNC 27695USA

We propose a positivity preserving entropy decreasing finite volume scheme for nonlinear nonlocal equations with a gradient flow *** properties allow for accurate computations of stationary states and long-time asymptotics demonstrated by suitably chosen test cases in which these features of the scheme are *** proposed scheme is able to cope with non-smooth stationary states,different time scales including metastability,as well as concentrations and self-similar behavior induced by singular nonlocal *** use the scheme to explore properties of these equations beyond their present theoretical knowledge.

关键词： Finite-volume method gradient flow nonlinear nonlocal equations

Transplant-associated thrombotic microangiopathy:a rare but deadly complication post orthotopic heart transplantation

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Journal of Geriatric Cardiology 2022年第6期19卷 485-486页

作者： jose Ruiz-Morales Maedeh Ganji Rohan Goswami Division of Advanced Heart Failure&Transplant Cardiology Mayo ClinicJacksonvilleFloridaUSA Cardiology Department University of FloridaJacksonvilleFloridaUSA

Thrombotic microangiopathy(TMA)is potentially life-threatening condition caused by small-vessel microthrombi and is associated with schistocyte formation,low platelets and end-organ damage that may not be reversible.[1,2]As a life-threatening condition,TMA recognition in hospitalized patients after organ transplantation is key to improving ***-associated TMA(TATMA)can occur after both solid organ or hematopoietic stem cell transplantation and often mimics other disease processes such as thrombotic throm-bocytopenic purpura(TTP)with similar constellation of symptoms during *** present a rare case of a patient with TATMA after orthotopic heart transplantation.

关键词： thrombotic microangiopathy orthotopic

Random Batch Particle Methods for the Homogeneous Landau Equation

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Communications in Computational Physics 2022年第4期31卷 997-1019页

作者： jose Antonio Carrillo Shi Jin Yijia Tang Mathematical Institute University of OxfordOxfordOX26GGUK School of Mathematical Sciences Institute of Natural SciencesMOE-LSCShanghai Jiao Tong UniversityShanghai200240P.R.China School of Mathematical Sciences Shanghai Jiao Tong UniversityShanghai200240P.R.China.

We consider in this paper randombatch particlemethods for efficiently solving the homogeneous Landau equation in plasma *** methods are stochastic variations of the particle methods proposed by Carrillo et al.[***.:X 7:100066,2020]using the random batch *** collisions only take place inside the small but randomly selected batches so that the computational cost is reduced to O(N)per time ***,our methods can preserve the conservation of mass,momentum,energy and the decay of *** numerical examples are performed to validate our methods.

关键词： Homogeneous Landau equation random batch particle method Coulomb collision

Phenolic compounds of green tea: Health benefits and technological application in food

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Asian Pacific Journal of Tropical Biomedicine 2016年第8期6卷 709-719页

作者： jose Manuel Lorenzo Paulo Eduardo Sichetti Munekata Meat Technological Center of Galicia Galicia Street No.4 Parque Tecnolgico de Galicia San Cibrao das Vinas Department of Food Engineering Faculty of Animal Science and Food Engineering University of Sao Paulo

Green tea has been an important beverage for humans since ancient times, widely consumed and considered to have health benefits by traditional medicine in Asian countries. Green tea phenolic compounds are predominately composed of catechin derivatives, although other compounds such as flavonols and phenolic acids are also present in lower proportion. The bioactivity exerted by these compounds has been associated with reduced risk of severe illnesses such as cancer, cardiovascular and neurodegenerative diseases. Particularly, epigallocatechin gallate has been implicated in alteration mechanisms with protective effect in these diseases as indicated by several studies about the effect of green tea consumption and mechanistic explanation through in vitro and in vivo experiments. The biological activity of green tea phenolic compounds also promotes a protective effect by antioxidant mechanisms in biological and food systems, preventing the oxidative damage by acting over either precursors or reactive species. Extraction of phenolic compounds influences the antioxidant activity and promotes adequate separation from green tea leaves to enhance the yield and/or antioxidant activity. Application of green tea phenolic compounds is of great interest because the antioxidant status of the products is enhanced and provides the product with additional antioxidant activity or reduces the undesirable changes of oxidative reactions while processing or storing *** this scenario, meat and meat products are greatly influenced by oxidative deterioration and microbial spoilage, leading to reduced shelf life. Green tea extracts rich in phenolic compounds have been applied to increase shelf life with comparable effect to synthetic compounds, commonly used by food industry. Green tea has great importance in general health in technological application, however more studies are necessary to elucidate the impact in pathways related to other diseases and food applications.

关键词： Phenolic profile Healthy Neurodegenerative diseases Extraction of polyphenols Antioxidant mechanism Food stability