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A Two-Scale Multi-Physics Deep Learning Model for Smart MEMS Sensors

Journal of Materials Science and Chemical Engineering 2021年第8期9卷 41-52页

作者： josé Pablo Quesada-molina Stefano Mariani Department of Civil and Environmental Engineering Politecnico di Milano Milano Italy Department of Mechanical Engineering Universidad de Costa Rica Rodrigo Facio Brenes Campus San José Costa Rica

Smart materials and structures, especially those bio-inspired, are often characterized by a hierarchy of length- and time-scales. Smart Micro Electro-Mechanical Systems (MEMS) are also characterized by different physical phenomena affecting their properties at different scales. Data-driven formulations can then be helpful to deal with the complexity of the multi-physics governing their response to the external stimuli, and optimize their performances. As an example, Lorentz force micro-magnetometers working principle rests on the interaction of a magnetic field with a current flowing inside a semiconducting, micro-structured medium. If an alternating current with a properly set frequency is let to flow longitudinally in a slender beam, the system is driven into resonance and the sensitivity to the magnetic field may result largely enhanced. In our former activity, a reduced-order physical model of the movable structure of a single-axis Lorentz force MEMS magnetometer was developed, to feed a multi-objective topology optimization procedure. That model-based approach did not account for stochastic effects, which lead to the scattering in the experimental data at the micrometric length-scale. The formulation is here improved to allow for stochastic effects through a two-scale deep learning model designed as follows: at the material scale, a neural network is adopted to learn the scattering in the mechanical properties of polysilicon induced by its polycrystalline morphology;at the device scale, a further neural network is adopted to learn the most important geometric features of the movable parts that affect the overall performance of the magnetometer. Some preliminary results are discussed, and an extension to allow for size effects is finally foreseen.

关键词： Machine Learning Artificial Neural Networks Polysilicon MEMS Uncer-tainty Quantification Lorentz Force Magnetometer

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A Two-Scale Multi-Physics Deep Learning Model for Smart MEMS Sensors

A Two-Scale Multi-Physics Deep Learning Model for Smart MEMS...

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作者： josé Pablo Quesada-molina Stefano Mariani Department of Civil and Environmental Engineering Politecnico di Milano Department of Mechanical Engineering Universidad de Costa RicaRodrigo Facio Brenes Campus

Smart materials and structures, especially those bio-inspired, are often characterized by a hierarchy of length-and time-scales. Smart Micro Electro-Mechanical Systems（MEMS） are also characterized by different physical phenomena affecting their properties at different scales. Data-driven formulations can then be helpful to deal with the complexity of the multi-physics governing their response to the external stimuli, and optimize their performances. As an example, Lorentz force micro-magnetometers working principle rests on the interaction of a magnetic field with a current flowing inside a semiconducting, micro-structured medium. If an alternating current with a properly set frequency is let to flow longitudinally in a slender beam, the system is driven into resonance and the sensitivity to the magnetic field may result largely enhanced. In our former activity, a reduced-order physical model of the movable structure of a single-axis Lorentz force MEMS magnetometer was developed, to feed a multi-objective topology optimization procedure. That model-based approach did not account for stochastic effects, which lead to the scattering in the experimental data at the micrometric length-scale. The formulation is here improved to allow for stochastic effects through a two-scale deep learning model designed as follows: at the material scale, a neural network is adopted to learn the scattering in the mechanical properties of polysilicon induced by its polycrystalline morphology;at the device scale, a further neural network is adopted to learn the most important geometric features of the movable parts that affect the overall performance of the magnetometer. Some preliminary results are discussed, and an extension to allow for size effects is finally foreseen.

关键词： Machine Learning Artificial Neural Networks Polysilicon MEMS Uncertainty Quantification Lorentz Force Magnetometer

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Pulmonary thromboembolism in a breast cancer woman receiving anastrozole and prophylactic nadroparin

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The Chinese-German Journal of Clinical Oncology 2007年第5期6卷 507-508页

作者： Maria josé molina-Garrido Carmen Guillén-Ponce Department of Oncology General University Hospital from Elche Alicante Spain

Hormonal treatment is widely accepted for the adjuvant treatment of breast carcinoma, in order to get a reduction in the synthesis of estrogen or to block estrogen receptors in tumors that are hormone dependent. There are multiple dsk factors that contribute to hypercoagulability in cancer patients. Hormonal therapy and chemotherapy are the main one. Type and stage of malignancy are other dsk factors; so age, immobility and surgery are. The main antineoplastic therapy with definitive hypercoagulable effect is tamoxifen, because it can cause reduction in the concentrations of antithrombin III and protein C. Here, we explain the case of a 75-year-old postmenopausal woman presenting with breast carcinoma who suffered from pulmonary thromboembolism during the treatment with anastrozole although she was taking nadropadn.

关键词：阿那曲唑那屈肝素治疗乳腺癌妇女肺动脉栓塞

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Resolution of pleural effusion in a IgD multiple myeloma after chemotherapy based on liposomal doxorubicin

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The Chinese-German Journal of Clinical Oncology 2007年第5期6卷 509-510页

作者： Maria josé molina-Garrido Carmen Guillén-Ponce Maria Guirado-Risueo Maria Angeles molina Maria Jesús molina Alfredo Carrato Department of Oncology General University Hospital from Elche Alicante Spain

IgD myelomas account for only 2% of all myelomas. This kind of hematological malignancy is severe and carries a bleak prognosis. Pleural effusion is very rare in multiple myeloma. We reported a case in which pleural e... 详细信息

关键词： multiple myeloma pleural effusion liposomal doxorubicin

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Cost Optimisation for Minimizing the Visual Impact of Ornamental Stone Quarrying. A Case Study in Murcia Region

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Journal of Geoscience and Environment Protection 2018年第2期6卷 74-88页

作者： josé molina-Ruiz María josé Martínez-Sánchez Carmen Pérez-Sirvent Mari Luz García-Lorenzo María Luz Tudela-Serrano Department of Geography Faculty of Geography University of Murcia Campus de la Merced Murcia Spain Department of Agricultural Chemistry Geology and Pedology Faculty of Chemistry University of Murcia Campus de Espinardo Murcia Spain Department of Mineralogy and Petrology Faculty of Geology University Complutense of Madrid Madrid Spain

Quarrying of ornamental stone has adverse effects that are both visual and environmental. This paper aims to develop a methodology for minimising the costs associated with reducing the visual impact of ornamental stone quarrying. This study uses digital topographical maps of the study zone and a GPS and GIS application to calculate the extent of the area affected by quarrying activities for each altitude designated in the work plan and to calculate the extent of the potential visual impact. The results obtained applying the proposed methodology for the selected area suggested that the potential visual impact is minimal for an altitude of 520 metres, this being the optimal point for the observer. When altitude increases, the potential visual impact increases and the optimal point for the observer diminishes until the highest impact altitude (740 m) is readied. The optimal point that the exploitation should reach is that at which the values of the diagram generated by the (%) area of potential visual impact and area of exploitation (%) intersect. The methodology allows the optimal altitude to be determined for mining exploitations and helps assess the viability of a given exploitation from an environmental point of view.

关键词： Restoration Costs Ornamental Stone Visual Impact Limestone Quarrying

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面朝大海西班牙某私宅

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室内设计与装修 2022年第7期 30-35页

作者： [西班牙]MariàCastelló(设计/摄影) [西班牙]joséAntonio molina 麦子(编译) 不详

该住宅位于西班牙布拉瓦海岸最北端的公路旁。此地属于PuigGros北坡的城区,这片城区沿着布拉瓦海岸,将城镇码头围合其中。住宅的地基是一道面海的坡地,布满了一种被称作“斑岩”的深色岩石。这些岩石质地坚硬。是由于火山喷发而形成的... 详细信息

该住宅位于西班牙布拉瓦海岸最北端的公路旁。此地属于PuigGros北坡的城区,这片城区沿着布拉瓦海岸,将城镇码头围合其中。住宅的地基是一道面海的坡地,布满了一种被称作“斑岩”的深色岩石。这些岩石质地坚硬。是由于火山喷发而形成的。典型的地中海气候时常会带来猛烈的北风,侵袭着海岸,因此极端天气也常常不期而遇。

关键词：火山喷发地中海气候极端天气海岸西班牙住宅

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Candidate genes underlying QTL for flowering time and their interactions in a wide spring barley(Hordeum vulgare L.) cross

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The Crop Journal 2021年第4期9卷 862-872页

作者： Ana M.Casas Carlota R.Gazulla Arantxa Monteagudo Carlos P.Cantalapiedra Marian Moralejo MPilar Gracia Francisco J.Ciudad William T.B.Thomas jose L.molina-Cano Scott Boden Bruno Contreras-Moreira Ernesto Igartua Department of Genetics and Plant Production Aula Dei Experimental Station(EEAD-CSIC)Avda Montanana 1005E-50059 ZaragozaSpain University of Lleida-AGROTECNIO Center Avda.Rovira Roure 19125198 LleidaSpain Instituto de Tecnologia Agraria Junta de Castilla y LeonITACyLP.O.Box 17247071 ValladolidSpain The James Hutton Institute InvergowrieDundee DD25DAUK Institut de Recerca i Tecnologia Agroalimentaries(UdL-IRTA) Avda Rovira Roure 19125198 LleidaSpain John Innes Centre Norwich Research ParkNorwich NR47UHUK Fundacion ARAID calle Maria de Luna 1150018 ZaragozaSpain Present address:Centro de Biotecnologia y Genomica de Plantas Universidad Politecnica de Madrid(UPM)and Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria(INIA)Madrid 28223Spain Present address:School of Agriculture Food and WineWaite Research InstituteUniversity of AdelaideGlen OsmondSA 5064Australia Present address:The European Bioinformatics Institute(EMBL-EBI) Wellcome Trust Genome CampusHinxtonUK

Response to vernalization and photoperiod are the main determinants controlling the time to flowering in temperate cereals. While the individual genes that determine a plant's response to these environmental signals are well characterized, the combinatorial effect on flowering time of allelic variants for multiple genes remains unresolved. This study investigated the genetic control of flowering-time in a biparental population of spring barley, derived from a wide cross between a late-flowering European and an early-flowering North-American cultivar. While the major flowering time genes are not segregating in the Beka ×Logan cross, large variation in flowering was observed. We identified five QTL, with both parents found to contribute early alleles. The catalog of QTL discovered aligns with several candidate genes affecting flowering time in barley. The combination of particular alleles at HvCEN, HvELF3 and HvFT1 in Logan are responsible for the earliness of this cultivar. Interestingly, earliness for flowering could be further enhanced, with Beka found to contribute three early alleles, including a QTL colocating with a HvFD-like gene, suggesting that there are diverse aspects of the flowering-time pathway that have been manipulated in these two cultivars. Epistatic interactions between flowering-time QTL or candidate genes were observed in field data and confirmed under controlled conditions. The results of this study link photoperiod-dependent flowering-time genes with earliness per se genes into a single model, thus providing a unique framework that can be used by geneticists and breeders to optimize flowering time in barley.

关键词： Barley Flowering HvELF3 HvCEN HvFT1

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基于网络分析仪的宽带MIMO信道探测

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电子设计技术 EDN CHINA 2008年第6期15卷 102-102,104,106,108,110,112页

作者： Rubén Ibernón-Fernández josé-María molina-García-Pardo josé-Víctor Rodríguez Leandro Juan-Llácer 喀他赫纳科技大学（UPCT）

本文介绍了一款宽带MIMO（多路输入多路输出）信道探测仪,它是基于多端口网络分析仪和快速开关而构建的,二者分别由笔记本电脑中的应用软件进行控制。该信道探测仪具有多种功能,可以配置频率带宽、发射天线和接收天线的数量等系统参数... 详细信息

本文介绍了一款宽带MIMO（多路输入多路输出）信道探测仪,它是基于多端口网络分析仪和快速开关而构建的,二者分别由笔记本电脑中的应用软件进行控制。该信道探测仪具有多种功能,可以配置频率带宽、发射天线和接收天线的数量等系统参数。唯一不便的是,在测量过程中信道必须保持稳定。

关键词：网络分析仪信道探测 MIMO 宽带笔记本电脑多路输出多路输入快速开关

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Mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： joséM.Izquierdo Centro de Biología Molecular Severo Ochoa(CBM) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

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Characteristics of Students in Three Schools of General Education and Council of Christian Churches of Angola in the City of Huambo-Angola on Sexuality for Educational Intervention

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Open Journal of Obstetrics and Gynecology 2016年第10期6卷 572-587页

作者： Natércia Paulina S. de Almeida Carolina Lino da Silva josé R. molina Garcia Alberto Capoco Sachiteque Welema Cipriano da Fonseca Carla Ramalho Frederico João Carlos Juliana Cezaltina Naduva Kahuli Hamilton dos Prazeres Tavares Central Hospital of Huambo Huambo Angola Medical School University of Porto Porto Portugal Huambo Provincial Department of Health Huambo Angola Medical School UniversityJose Eduardo dos Santos Huambo Angola Municipal Hospital of Caála Medical School University José Eduardo dos Santos Huambo Angola

Sexual education is a social responsibility and is a part of the coherent strategy referred to the introduction in schools in Angola. It was made of a prospective, descriptive and longitudinal study that has been characterized the knowledge of sexual education of students in general education in three schools and the Council of Christian Churches in Huambo-Angola in July 2015. The sample consisted of 386 students chosen randomly;there are no sexual education programs in the education system, there are taboos on sexuality, the respondents do not know the sexual organs and much less contraceptive methods, there are still taboos in sexuality theme approach with adolescents, the results showed.

关键词： Characterization Students Schools Knowledge Sexuality

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