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Enhanced depth OCT imaging of the lamina cribrosa for 24 hours

International Journal of Ophthalmology(English edition) 2017年第2期10卷 306-309页

作者： Pedro Naranjo Bonilla Rafael Giménez Gómez David Ríos Jiménez maría Luísa Varas Fabra maría del Carmen Munoz Villanueva Rocío García Catalán Pilar Font Ugalde maría Soledad Poblador Fernández joséLuís Lancho Alonso josémaría gallardo galera Department of Ophthalmology Reina Sofia University HospitalCordoba 14004Spain Methodological Support to Research Maimonides Institute for Biomedical ResearchReina Sofia University HospitalCordoba 14004Spain Department of Medicine UCO Maimonides Institute for Biomedical ResearchReina Sofia University HospitalCordoba 14004Spain Department of Morphological Sciences Faculty of MedicineCordoba 14004Spain

The lamina cribrosa thickness（LCT） could be affected by dynamic changes in its *** spectral-domainoptical coherence tomography（SD-OCT）,we have studied the behaviour of the laminar region in 14 young subjects over 24 *** changes in LCT were observed,depending on the time at which the measurement was taken,with the maximum thickness being observed at 7.30 p.m.,and the minimum at 7.30 *** finding could suggests a circadian pattern in the LCT thickness in healthy subjects,which could have implications for the classification,diagnosis and prognosis of both normal and glaucomatous subjects.

关键词： lamina cribrosa laminar region glaucoma optical coherence tomography twenty-four-hours

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HLA B27 as Predisposition Factor to Suffer Age Related Macular Degeneration

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Cellular & Molecular Immunology 2009年第4期6卷 303-307页

作者： Enrique Villegas Becerril Rafael Gonzalez Fernandez Luis Perula Torres Manuel Santos Lacomba jose maria gallardo galera Hospital Universitario Reina Sofia Cordoba Spain Faculty of Medicine University of Cordoba Spain Hospital Universitario Reina Sofia C/Conchita Cintron n 4 Atico 2 CP 14011

To research whether specific alleles HLA class Ⅰ （HLA-A and HLA-B） and class Ⅱ （HLA-DR） are risk factors for the development of exudative type of Age Related Macular Degeneration（ARMD）, HLA antigens are expressed both in normal and affected eyes with ARMD. We designed a prospective case-controlled study. We recruited 75 patients with choroidal neovascuiarization predominantly classic or occult, secondary to ARMD, and treated with photodynamic therapy. Two hundred and fifty patients over 55 years old, without ophthalmologic pathology who went to hospital for an analytical routine check were used as control. The analysis of the data shows a significant difference between two groups. Allele HLA-B27 correlated positively with ARMD （p 〈 0.0113）. However, we didn＇t find alleles negatively associated. Thus HLA-B27 is an allele predisposed to suffer ARMD.

关键词： HLA alleles ARMD HLA B27 patient with ARMD

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