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Relationships between soil pollution by heavy metals and melanin-dependent coloration of a fossorial amphisbaenian reptile

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Integrative Zoology 2022年第4期17卷 596-607页

作者： joséMARTÍN Pablo RECIO Gonzalo RODRÍGUEZ-RUIZ Isabel BARJA Eduardo GUTIÉRREZ luis VGARCÍA Departamento de Ecología Evolutiva Museo Nacional de Ciencias NaturalesCSICMadridSpain Departamento de Zoología Facultad de BiologíaUniversidad Autónoma de MadridMadridSpain Centro de Investigación en Biodiversidad y Cambio Global(CIBC-UAM) Universidad Autónoma de MadridMadridSpain Departamento de Biogeoquímica Ecología Vegetal y MicrobianaInstituto de Recursos Naturales y Agrobiología de SevillaCSICSevillaSpain

Melanin is the basis of coloration in many animals,and although it is often used in communication,thermoregulation,or camouflage,melanin has many other physiological *** example,in polluted habitats,melanin can have a detoxifying *** coloration would help to sequester in the skin the heavy metal contaminants from inside the body,which will be expelled to the exterior when the skin is ***,animals should have evolved more melanic colorations in more polluted habitats(“industrial melanism”hypothesis).We examined whether the fossorial amphisbaenian reptile,Trogonophis wiegmanni,is able to eliminate heavy metals,derived from soil pollution by seagull depositions,through sloughing its *** results suggest a covariation between levels of soil pollution by heavy metals and the concentration of heavy metals in the sloughed skins of *** suggests that amphisbaenians may expel heavy metals from their bodies when they slough the *** also tested whether amphisbaenians inhabiting soils with higher levels of heavy metal pollution had darker(melanin-dependent)body ***,contrary to predictions from the“industrial melanization”hypothesis,we found a negative relationship between soil pollution and proportions of melanic *** contradictory result could,however,be explained because heavy metals have endocrine disruption effects that increase physiological stress,and higher stress levels could result in decreased *** suggest that although amphisbaenians might have some detoxifying mechanism linked to melanin in the skin,this process might be negatively affected by stress and result ineffective under conditions of high soil pollution.

关键词： amphisbaenians coloration fossorial reptiles heavy metals melanin soil pollution

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Synthesis and Characterization of Hydrogels Based on Potato Starch/Poly(vinyl Alcohol)/N,N′-Methylenebisacrylamide

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Journal of Renewable Materials 2022年第8期10卷 2179-2201页

作者： Diego David Pinzón-Moreno Eder Clidio Vicuña-Galindo joséVulfrano González-Fernández joséluis Soto-Gonzales María Verónica Carranza-Oropeza Faculty of Chemistry and Chemical Engineering National University of San MarcosLima15081Peru

Several hydrogels were synthesized by free-radical polymerization in an aqueous medium based on potato starch(PS),poly(vinyl alcohol)(PVA),and N,N′-Methylenebisacrylamide(MBAm),being possible to study these hydrogels as a function of the proportion of components *** this way,the products generated from the synthesis were characterized by swelling and deswelling kinetics,the first swelling being verified with Schott and statistical models,allowing to contrast the proximity between the experimental and theoretical ***,water retention in soil(R%),spectroscopy(FTIR),morphological(SEM),and thermal(TGA and DSC)analysis allowing to know the intrinsic characteristics of the material,increasing in general terms the knowledge of this type of *** this context,it was possible to verify the characteristics and effectiveness of the synthesis and crosslinking of the main *** experimental results obtained show that the synthesized hydrogels present representative swellings consistent with kinetic and statistical models,optimal thermal stability depending on the amount of crosslinker,and excellent water retention in environments such as soil,presenting it as an excellent alternative to be used in agro-industrial applications in an eco-friendly way.

关键词： Hydrogel potato starch polyvinyl alcohol N,N′-Methylenebisacrylamide kinetic swelling and deswelling water retention thermal characterization morphology characterization

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Depth of closure:New calculation method based on sediment data

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International Journal of Sediment Research 2018年第2期33卷 198-207页

作者： luis Aragonés jose Ignacio Pagán Isabel López josé C.Serra Department of civil engineering University of Alicante Department of transportation ETSI Caminos Polytechnic University of Valencia

Obtaining depth of closure(DoC) in an accurate manner is a fundamental issue for coastal engineering,since good results for coastal structures and beach nourishment depend mainly on DoC. Currently, there are two methods for obtaining the DoC, mathematical formulations and profile surveys. However, these methods can incur important errors if one does not take into account the characteristics and morphology of the area, or if one does not have a sufficiently long time series. In this work the DoC is obtained from the break in the trend of the sediment with the depth, that is, in general with the increase of the depth a decrease in the size of the sediment takes place. However, at one point this tendency changes and the size increases, and then decreases again. When comparing the point where the minimum sediment size occurs before the increase, it is observed that the error incurred is small compared to other methods. If the Standard Deviation of Depth Change(SDDC) method is considered as the most accurate method, the error incurred by the proposed method is less than 7%. In addition, it can be seen that the dispersion of the sediment method always occurs outside the zone of bar movement. Whereas in the methods of profiles survey(using 2 cm precision profiles), sometimes the DoC is obtained within the active zone of bar movement. In addition, where the relative minimum of the median sediment size is found, and the sizes of 0.063 and 0.125 mm predominate in the composition of the sample. Therefore, this new method allows the precise location of the DoC to be obtained in a fast and simple way. Furthermore, this method has the advantage that it is not affected by the modifications that may be experienced by both the study area and the cross-shore beach profile.

关键词： Depth of Closure Median sediment size Profile surveys Profile change GIS

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Gastrointestinal tuberculosis:An autopsy-based study

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Infectious Medicine 2023年第2期2卷 122-127页

作者： Julio Cesar Mantilla Juan joséchaves Ferney Africano-Lopez Néstor Blanco-Barrera Marta Juliana Mantilla Department of Pathology Universidad Industrial de SantanderBucaramanga 680002Colombia Department of Pathology Hospital Universitario de SantanderBucaramanga 680002Colombia Department of Pathology Fundación Universitaria de Ciencias de la SaludBogotá111411Colombia Department of Gastroenterology Gastrocenter and Medical SpecialitiesIpiales 524061Colombia Department of Gastroenterology Universidad Militar Nueva GranadaBogotá250240Colombia Department of Rheumatology Universidad de la SabanaChía 250001Colombia

Background:Tuberculosis is a disease of great relevance since it is one of the leading causes of morbidity and mortality *** tuberculosis is an unusual *** is defined as the involvement of any segment of the digestive tract,associated viscera,and *** study’s main objective is to collect information from autopsies of patients diagnosed with gastrointestinal tuberculosis in a Pathology reference center in ***:This is a retrospective and descriptive study of autopsy reports.A total of 4,500 autopsies were performed between January 2004 and December *** inclusion criteria were authorization of a family member following local law regulations and a final autopsy diagnosis of gastrointestinal tuberculosis using microscopic ***:Forty-eight patients with gastrointestinal tuberculosis autopsies were included in our *** of the patients were male(n=35,72.9%)with a median age of 40.5 years *** immunodeficiency virus infection history was reported in 28 cases(58.33%).The most affected gastrointestinal tract site was the terminal *** and thickened epithelium were common autopsies macroscopic *** multiorgan compromise was a relevant finding in patients with gastrointestinal ***:Gastrointestinal tuberculosis is a disease of great importance,being its diagnosis a clinical *** can be reported in a high percentage of cases,so autopsy diagnosis can help reveal more accurate data about this condition.

关键词： Gastrointestinal tuberculosis Autopsy Forensic pathology Infections Colombia

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Evolution of wheat architecture,physiology,and metabolism during domestication and further cultivation:Lessons for crop improvement

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The Crop Journal 2023年第4期11卷 1080-1096页

作者： Arturs Katamadze Omar Vergara-Díaz Estefanía Uberegui Ander Yoldi-Achalandabaso josé luis Araus Rubén Vicente Plant Ecophysiology and Metabolism Group Instituto de Tecnologia Química e Biológica António XavierUniversidade Nova de LisboaP-2780 OeirasPortugal Genetics and Genomics of Plant Complex Traits Instituto de Tecnologia Química e Biológica António XavierUniversidade Nova de LisboaP-2780 OeirasPortugal FisioClimaCO_(2) Group Department of Plant Biology and EcologyFaculty of Science and TechnologyUniversity of the Basque CountryE-48940 LeioaSpain Integrative Crop Ecophysiology Group Section of Plant PhysiologyFaculty of BiologyUniversity of BarcelonaE-08028 Barcelona&AGROTECNIO-CERCA CenterE-25198 LleidaSpain

In recent decades,genetic advances in yield improvement in the major cereal crops,including wheat,has stagnated or proceeded at a slower rate than is required to meet future global food demand,particularly in the face of climate *** reverse this situation,and in view of the future climate scenario,there is a need to increase the genetic diversity of wheat to increase its productivity,quality,stability,and adaptation to local *** abundant genetic resources and literature are a basis for wheat ***,many species,such as wild relatives,landraces,and old cultivars have not been studied beyond their agronomic characteristics,highlighting the lack of understanding of the physiological and metabolic processes(and their integration) associated with higher productivity and resilience in limiting *** studies using wheat ancestors and modern cultivars may identify novel traits that have not previously been considered,or have been underestimated,during domestication and breeding,but that may contribute to future food *** review describes existing wheat genetic diversity and changes that occurred during domestication and breeding,and considers whether mining natural variation among wheat ancestors offers an opportunity to enhance wheat agronomic performance,spike architecture,canopy-and organ-level photosynthetic capacity,and responses to abiotic stress,as well as to develop new wheat hybrids.

关键词： Breeding Landraces Photosynthesis Wild relatives Yield

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Effect of asymmetric rolling under high friction coefficient on recrystallization texture and plastic anisotropy of AA1050 alloy

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Transactions of Nonferrous Metals Society of China 2019年第11期29卷 2262-2272页

作者： Bianca.Delazari ZANCHETTA Vanessa.Karoline DA.SILVA Vitor.luis.SORDI joséBenaque RUBERT Andrea Madeira KLIAUGA Graduation Program in Materials Science Federal University of Sao CarlosRod.Joao Leme dos Santos km 11018052-780 SorocabaBrazil Department of Materials Engineering Federal University of Sao CarlosRod.Washington Luis km 23513565-905 Sao CarlosBrazil Department of Mechanical Engineering Federal University of Sao CarlosRod.Washington Luiskm 23513565-905 Sao CarlosBrazil

In asymmetric rolling(ASR) the circumferential velocities of the working rolls are different. This yields a complex deformation mode with shear, compression and rigid body rotation components. The main microstructural modification is on crystallographic texture, and, for aluminium alloys, this may improve the deformability after recrystallization. This work correlated the process variables, thickness reduction per pass(TRP) and velocity ratio between the upper and bottom rolls, with the texture development and the plastic properties after annealing. Finite element(FE) simulations were performed to quantify the influence of the strain components. Experimental data on texture, and plastic anisotropy were analyzed. In the sheet centre a crystallographic rotation of the compression components about the TD(transverse direction) axis was obtained, which yielded the development of {111}//ND(normal direction) texture components. On the surfaces the local variation of the velocity gradients caused an extra rotation component about ND. This yielded the increment of rotated cube components. After annealing the main texture components at the sheet centre were maintained and the texture intensity decreased. The planar anisotropy(△r) was reduced but the normal anisotropy and deep drawability obtained by the Erichsen test were similar for all conditions. The most favourable reduction of △r was obtained at a velocity ratio of 1.5 and TRP of 10%.

关键词： asymmetric rolling aluminium alloy X-ray diffraction finite element analysis stress/strain measurements plasticity

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Co-Simulation of an SRG Wind Turbine Control and GPRS/EGPRS Wireless Standards in Smart Grids

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IEEE/CAA Journal of Automatica Sinica 2021年第3期8卷 656-663页

作者： Andre Luiz de Oliveira Carlos Eduardo Capovilla Ivan Roberto Santana Casella joséluis Azcue-Puma Alfeu J.Sguarezi Filho University of Sao Paulo Sao Paulo 05508-010Brazil Federal University of ABC Santo Andre 09210-580Brazil

Wind energy can be considered a push-driver factor in the integration of renewable energy sources within the concept of smart *** its full deployment,it requires a modern telecommunication infrastructure for transmitting control signals around the distributed generation,in which,the wireless communication standards stand out for employing modern digital modulation and coding schemes for error correction,in order to guarantee the power plant *** some developing countries,such as Brazil,the high penetration of commercial mobile wireless standards GPRS and EGPRS(based on GSM technology)have captivated the interests of the energy sector,and they now seek to perform remote monitoring and control *** this context,this article presents a comparative performance analysis of a wireless control system for a wind SRG,when a GPRS or EGPRS data service is *** system performance is analyzed by co-simulations,including the wind generator dynamics and the wireless channel *** satisfactory results endorse the viability and robustness of the proposed system.

关键词： General packet radio service(GPRS)/enhanced GPRS(EGPRS) smart grids switched reluctance generator(SRG) wind energy wireless communications

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A tumor-associated heparan sulfate-related glycosaminoglycan promotes the generation of functional regulatory T cells

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Cellular & Molecular Immunology 2023年第12期20卷 1499-1512页

作者： Leticia Martín-Cruz Marcos Viñuela Ioanna Kalograiaki Alba Angelina Paola Oquist-Phillips Irene Real-Arévalo Francisco Javier Cañada joséIgnacio Tudela luis Moltó Jesús Moreno-Sierra joséluis Subiza Oscar Palomares Department of Biochemistry and Molecular Biology School of ChemistryComplutense University of MadridMadridSpain Inmunotek Alcaláde HenaresMadridSpain Fundación Investigación Hospital Clínico San Carlos Martin Lagos s/n28040MadridSpain Centro de Investigaciones Biológicas Margarita Salas CSICRamiro de Maetzu 928040MadridSpain CIBER de Enfermedades Respiratorias(CIBERES)Avda Monforte de Lemos3-528029MadridSpain Servicio de Urología Hospital Clínico San CarlosUniversidad Complutense de MadridMartín Lagos s/n28040MadridSpain

Functional Tregs play a key role in tumor development and progression,representing a major barrier to anticancer *** mechanisms by which Tregs are generated in cancer and the influence of the tumor microenvironment on these processes remain incompletely ***,by using NMR,chemoenzymatic structural assays and a plethora of in vitro and in vivo functional analyses,we demonstrate that the tumoral carbohydrate A10(Ca10),a cell-surface carbohydrate derived from Ehrlich’s tumor(ET)cells,is a heparan sulfate-related proteoglycan that enhances glycolysis and promotes the development of tolerogenic features in human ***10-stimulated human DCs generate highly suppressive Tregs by mechanisms partially dependent on metabolic reprogramming,PD-L1,IL-10,and ***10 also reprograms the differentiation of human monocytes into DCs with tolerogenic *** solid ET-bearing mice,we found positive correlations between Ca10 serum levels,tumor size and splenic Treg *** of isolated Ca10 also increases the proportion of splenic Tregs in tumor-free ***,we provide evidence supporting the presence of a circulating human Ca10 counterpart(Ca10H)and show,for the first time,that serum levels of Ca10H are increased in patients suffering from different cancer types compared to healthy *** note,these levels are higher in prostate cancer patients with bone metastases than in prostate cancer patients without ***,we reveal novel molecular mechanisms by which heparan sulfate-related structures associated with tumor cells promote the generation of functional Tregs in *** discovery of this novel structural-functional relationship may open new avenues of research with important clinical implications in cancer treatment.

关键词： Tumoral carbohydrate A10 Heparan sulfate-related proteoglycan Cancer immunology Dendritic cell Regulatory T cell

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Dealing with Multisource Information for Estuarine Flood Risk Appraisal in Two Western European Coastal Areas

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International Journal of Disaster Risk Science 2022年第2期13卷 199-213页

作者： Ana Rodrigues Rilo Alexandre Manuel de Oliveira Soares Tavares Paula Maria dos Santos Freire josé luis Zêzere Estuarine and Coastal Zones Unit LNEC-National Civil Engineering Laboratory.1700-075 LisbonPortugal Centre of Geographical Studies Institute of Geography and Spatial PlanningUniversidade de Lisboa1700-066 LisbonPortugal Centre for Social Studies and Earth Sciences Department Coimbra University3030-790 CoimbraPortugal

Estuaries are usually affected by compound flooding triggers that cause diverse territorial *** fluvial flood risk assessment frameworks are well established in the literature,integrated management instruments that deal with estuarine flood risk remain incomplete and often *** research presents a methodology to extract relevant information from multiple sources post-event and a database building process that is applied to two contrasting estuaries(the Tagus River estuary in Portugal,and the Shannon River estuary in Ireland)in the Western European coastal ***,a total of 274 documents were analyzed and the information was stored in two *** correspondence analysis was applied to extract the most informative and relevant estuarine flood *** integrated estuarine flood risk assessment framework is presented and discussed based on the extracted *** framework is driven by two distinct dimensions(oceanic and hydrographic)and revealed the transversal position of triggers of estuarine floods,reflecting the compounding effects usually present in these *** results also highlight two levels of flood risk mostly based on damage typology.

关键词： Estuarine floods Estuarine flood indicators Multiple correspondence analysis Post-hazard multisource information Western Europe

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Aggregate Consumption： An Analysis by Numeric Simulation

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Chinese Business Review 2017年第8期16卷 403-413页

作者： Ricardo luis chaves Feij6 University of Sao Paulo Ribeirao Preto Brazil

It is estimated that the aggregate consumption behavior of families by computational procedures in an abstract model contemplates the maximization of agent utility in each period （two dates）, the attendance of budgetary restrictions and the conditions of general equilibrium （without production）. It uses the technique of selection of candidate points in a simulation process with a portfolio of efficient assets and a hypothesis for the process of determining the returns of the securities： A GARCH process. By this technique, it compares the stochastic volatility patterns between the artificial series, obtained in the simulation, and the real series of household aggregate consumption in the US and Brazil.

关键词： aggregate consumption numeric simulation general equilibrium stochastic process

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