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Touristic urbanization and greening of coastal dune fields:A long-term assessment of a temperate sandy barrier of Argentina

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Journal of Geographical sciences 2025年第1期35卷 206-230页

作者： GARZO Pedro Andrés DADON joséRoberto IsLA Federico Ignacio Instituto de Investigaciones Marinas y Costeras(IIMyC-CONICET/UNMDP) Av.Juan B.Justo 2550Mar del Plata7600Buenos AiresArgentina Instituto de Geología de Costas y del Cuaternario Dr.Enrique J.schnack(IGCC-CIC/UNMDP) Funes 3350Mar del Plata7600Buenos AiresArgentina Facultad de Arquitectura Diseño y UrbanismoCentro de Investigaciones Gestión de Espacios Costeros(GEC-FADU/UBA)Universidad de Buenos AiresIntendente Güiraldes 2160Pabellón ⅢPiso 4Ciudad Autónoma de Buenos Aires1428Argentina Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET) Buenos AiresArgentina

Dune barrier systems represent highly sought-after coastal landscapes for tourism and urban development around the ***,a century ago,they were considered hazardous environments due to their great dynamic *** a result,stabilization practices were considered *** systematic introduction of fast-growing exotic trees helped stabilize the sand,making it easier for tourism urbanization to take place,but also leading to erosion *** paper aims to assess long-term changes in vegetation cover over a large temperate barrier in *** complex region includes urban resorts,afforestation zones,and protected areas.A GIs-based geospatial analysis was conducted using a large satellite database(>350 images),and the future evolution of the vegetation was *** results revealed two primary spatiotemporal patterns associated with a gradual expansion of vegetation cover,accompanied by a concurrent reduction in sandy *** 1986,the dune area comprised 75%more surface than vegetation,whereas in 2021,it represented 60%less than ***,the 2050 scenario suggests a potential 40%reduction of dunes in certain *** is necessary to enhance management actions aimed at maintaining dune mobility and ensuring local and regional sediment ***-term management strategies must focus on restoring native plant communities and controlling invasive species,and avoiding new dune fixation initiatives based on the introduction of exotic species.

关键词： nature reserves afforestation sediment balance dune management NDVI

Longitudinal assessment of measured and estimated glomerular filtration-rate in autosomal dominant polycystic kidney disease:Real practice experience

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World Journal of Nephrology 2025年第1期14卷 99-109页

作者： juan M Fernandez joséC Rodriguez-Pérez M Mercedes Lorenzo-Medina Fancisco Rodriguez-Esparragon juan C Quevedo-Reina Carmen R Hernandez-socorro Medical Manager southern Europe Baxter Healthcare Ltd.Madrid 28830Spain Escuela de Doctorado Universidad De Las Palmas De Gran CanariaLas Palmas 35001Canary IslandsSpain Department of Research Universidad Fernando Pessoa CanariasLas Palmas 35450Canary IslandsSpain Department of Clinical Chemistry Hospital Universitario De Gran Canaria Doctor NegrínLas Palmas 35010Canary IslandsSpain Department of Research Hospital Universitario De Gran Canaria Doctor NegrínLas Palmas 35010Canary IslandsSpain Department of Nephrology Hospital Universitario De Gran Canaria Doctor NegrínLas Palmas 35010Canary IslandsSpain Department of Radiology Hospital Universitario De Gran Canaria Doctor NegrínLas Palmas 35010Canary IslandsSpain

BACKGROUND Equations for estimation glomerular filtration rate(eGFR)have been associated with poor clinical performance and their clinical accuracy and reliability have been called into *** To assess the longitudinal changes in measured glomerular filtration rate(mGFR)in patients with autosomal dominant polycystic kidney disease(ADPKD).METHODs Analysis of an ambispective data base conducted on consecutive patients diagnosed with *** mGFR was assessed by iohexol clearance;while eGFR was calculated by three different formulas:(1)The chronic kidney disease epidemiology collaboration(CKD-EPI);(2)Modification of diet in renal disease(MDRD);and(3)The 24-hour urine creatinine clearance(CrCl).The primary end-points were the mean change in mGFR between the baseline and final visit,as well as the comparison of the mean change in mGFR with the change estimated by the different *** Thirty-seven patients were included in the *** compared to baseline,month-6 mGFR was significantly decrease by-4.4 mL/minute±10.3 mL/minute(P=0.0132).However,the CKD-EPI,MDRD,and CrCl formulas underestimated this change by 48.3%,89.0%,and 45.8%respectively,though none of these differences reached statistical significance(P=0.3647;P=0.0505;and P=0.736,respectively).The discrepancies between measured and estimated glomerular filtration rate values,as evaluated by CKD-EPI(r=0.29,P=0.086);MDRD(r=0.19,P=0.272);and CrCl(r=0.09,P=0.683),were not correlated with baseline mGFR *** This study indicated that eGFR inaccurately reflects the decline in mGFR and cannot reliably track changes over *** poses significant challenges for clinical decision-making,particularly in treatment strategies.

关键词： Autosomal dominant polycystic kidney disease Glomerular filtration rate End-stage kidney disease Iohexol Chronic kidney disease epidemiology collaboration Modification of diet in renal disease

sickle Crisis Precipitated by Pneumonia: A Diagnostic and Therapeutic Challenge

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Journal of Biosciences and Medicines 2025年第1期13卷 255-263页

作者： David Fernando Ortiz-Pérez Luisa María Petro-Noriega Margarita Rosa Burgos-Peña Marlon josé Rosado-Mendoza santiago sánchez-Rojas Cristina De Jesús Portillo-Monterrosa Daniel de Jesús González-Villarreal juan Pablo de la Ossa Díaz John sebastián Osorio-Muñoz Manuel Esteban Ortiz Pérez Ana María garcía-suárez Department of Internal Medicine Cartagena del Mar Medical Center Cartagena Colombia Internal Medicine Program Universidad del Sin Cartagena Colombia Faculty of General Medicine Universidad del Sin Cartagena Colombia Faculty of General Medicine Universidad Surcolombiana Neiva Colombia Faculty of General Medicine Universidad de Sucre Sincelejo Colombia Faculty of General Medicine Universidad Libre Barranquilla Colombia Faculty of General Medicine Fundacin Universitaria Navarra Neiva Colombia Faculty of General Medicine Universidad de Cartagena Cartagena Colombia

sickle cell anemia (sCA) is a prevalent genetic disorder primarily affecting individuals of African descent and populations in malaria-endemic regions, with significant global public health implications. sickle cell crises are their most common acute complication, characterized by episodes of intense pain and systemic manifestations that impair quality of life and impose a high healthcare burden. We present the case of a 19-year-old male diagnosed with sCA since the age of two, who developed a sickle cell crisis precipitated by right basal pneumonia. The patient exhibited sudden-onset, cyclic lumbar pain with progressive dyspnea. Initial management included multimodal pain control, volume optimization, and targeted antimicrobial therapy to achieve clinical stabilization. This case underscores the importance of a comprehensive approach to managing sickle cell crises, addressing both symptomatic relief and the prevention and treatment of complications. It also highlights the need for public health strategies promoting early diagnosis, access to disease-modifying therapies such as hydroxyurea, and interdisciplinary follow-up to mitigate the socioeconomic and clinical impact of sCA.

关键词： sickle Cell Anemia sickle Cell Crisis Pain Management Pneumonia Hydroxyurea

Preparation and Characterization of Flexible, Transparent and Thermally stable Aromatic Co-polyamides

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Chinese Journal of Polymer science 2019年第2期37卷 136-141页

作者： josé Antonio Tec-sánchez Andrés Iván Oliva Arias Manuel Aguilar-Vega juan Valerio Cauich-Rodríguez josé Luis santiago-garcía Unidad de Materiales Centro de Investigación Científica de Yucatán A. C. Centro de Investigación y de Estudios Avanzados del IPN Unidad Mérida Departamento de Física Aplicada

Two aromatic co-polyamides were synthesized combining two diacid monomers containing bulky pendant groups, 5-(9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximido)isophthalic acid(DEAIA) and 5-tert-butylisophthalic acid(TERT), with 4,4′-(hexafluoroisopropylidene)dianiline(HFA) or 2,3,5,6-tetramethyl-1,4-phenylenediamine(Durene) by direct polycondensation. The structures of the obtained aromatic co-polyamides were confirmed by FTIR, Raman and 1 H-NMR. The co-copolyamide films, DHTH and DDTD, exhibited rms-roughness values between 0.94 and 1.60 nm, respectively. Moreover, they presented good thermal stability up to300 °C. Young's moduli of the co-polyamide films were between 4.1 and 4.3 GPa. X-ray diffraction results showed that the co-polyamide films were amorphous due to the incorporation of both bulky pendant groups, tert-butyl and dibenzobarrelene. The combination of bulky pendant groups provided intrinsically transparent co-polyamide films with a transmittance higher than 88% in the range of 400-780 *** to these outstanding film and optical properties, they are suggested to be flexible substrates in applications for solar cell and other portable electronic devices.

关键词： Co-polyamides Flexible films Transmittance Thermal stability Polycondensation

Multiple Chemical sensitivity: A sickness of suffering, Not of Dying. Descriptive study of 33 Cases

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Health 2025年第1期17卷 65-81页

作者： Blanca Navas-soler Aarón Gutiérrez-Pastor Antonio Palazón-Bru Jorge Vallejo-Ortega Álex Méndez-Jover Celia santano-Pérez Carmen seguí-Pérez Marc seguí-Pérez sonia Cascant-Pérez juan Carlos López-Corbalán Míriam Pérez-Cardona Ramón Pérez-Doménech Antonio Hernández-garcía Patricia Lorca-Amorrich Ana Belén Llinares-Llinares Cristina Valverde-Cámara Rosa María Bustos-Martínez juan Manuel Núñez-Cruz Isidro Hernández-Isasi josé juan Martínez-Pérez josé Manuel santano-López María Dolores Jover-Ríos juan Méndez-Mora josé Miguel seguí-Ripoll Internal Medicine service University Hospital of San Juan de Alicante Alicante Spain Family and Community Medicine service University Hospital of San Juan de Alicante Alicante Spain Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (FIsABIO) University Hospital of San Juan de Alicante Alicante Spain Faculty of Physics University of Alicante Alicante Spain Department of Clinical Medicine Medical School University Miguel Hernandez de Elche Alicante Spain CEU Veterinary school University Cardenal Herrera Alfara del Patriarca Campus Valencia Spain secondary school Marist Brothers High School Alicante Spain Primary Medicine Hospital Francesc Borgia of Gandia Valencia Spain Faculty of Medicine CEU Cardenal Herrera University Alfara del Patriarca Campus Valencia Spain Faculty of Economics University of Alicante Alicante Spain Department of Internal Medicine Hospital La Vega Baja of Orihuela Alicante Spain

Objective: We describe patients with MCs, the evolution of the Quick Environmental Exposure and sensitivity Inventory (QEEsI) score with a special focus on people whose fillings were removed. Methods: We have conducted a retrospective longitudinal cohort study in patients diagnosed with MCs and attended in the outpatient Internal Medicine department of the University Hospital of san juan de Alicante, from January 1, 2008 to January 1, 2021. sociodemographic, clinical, QEEsI and treatment-related variables were collected. We performed descriptive and inferential analyses. Mixed linear models were used to analyze the QEEsI. Calculations were carried out with an α error of 5%. Results: Thirty-three patients were included (72.7% women, mean age 56.2). MCs was mainly triggered by mercury (N = 20) and food intolerance (N = 22). The mean interval from symptoms onset was 120 months (sD 81.6). 114 QEEsIs were analyzed: 82 (N = 17 without amalgams) and 32 (N = 16 with amalgams). In patients without amalgams, severity scores increased across all subscales except the masking index (vs. with amalgams). Mean scores for the group without amalgams (vs. with amalgams) were: chemical intolerance, 62.8 points (vs. 63.4 and 46.7);other intolerances, 52.7 points (vs. 62.8 and 50.3);symptom severity, 63.2 (vs. 76.7 and 63.3);masking index, 3.9 (vs. 3.2 and 2.8);and life impacts, 63.1 (vs. 58.4 and 49.8). Conclusion: The profile of patient with MCs is a middle-aged woman who is a frequent user of healthcare services, presents a long diagnostic delay and has borne a great personal, work and socioeconomic impact. The QEEsI is useful for the clinical follow-up of patients, including the optimal treatment response in the case of amalgams. Clinical significance: People affected by Multiple Chemical sensitivity deserve the attention, understanding and help of health professionals and family members, to face an invisible illness for those who do not suffer from it. support is needed and doctors

关键词： Chemical sensitivity Electromagnetic sensitivity Mercury Poisoning Amalgams QEEsI

Avian-power line interactions in the Gobi Desert of Mongolia:are mitigation actions effective?

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Avian Research 2021年第3期12卷 382-390页

作者： Adrian Orihuela-Torres juan MPérez-garcía Zebensui Morales-Reyes Lara Naves-Alegre joséAsánchez-Zapata Esther sebastián-González Área de Ecología Departamento de Biología AplicadaUniversidad Miguel Hernández de ElcheAvda.Universidad s/n03202 ElcheAlicanteSpain Departamento de Ecología Universidad de AlicanteCtra.San Vicente del Raspeig s/n03690 San Vicente del RaspeigAlicanteSpain

Background:Electrocution and collisions on power lines are among the leading causes of non-natural mortality for *** lines are exponentially increasing,particularly in developing countries,but mitigation strategies to prevent bird mortality are *** combines a recently increased power line network,an abundant raptor population,a dangerous crossarm configuration and a habitat with no natural perches,producing many bird-power line *** aim is to assess the bird mortality caused by power lines in the Gobi Desert of Mongolia,to determine the factors increasing the risk of bird electrocution,and to evaluate the effectiveness of used retrofitting ***:In July 2019 we covered 132.9 km of 15 kV power lines checking 1092 *** also conducted bird tran-sects to record raptor and corvid richness and abundance,to assess species vulnerability to ***:We recorded 76 electrocuted birds of 7 *** rate was 6.96 birds/100 *** most affected species were Common Raven(Corvus corax)and Upland Buzzard(Buteo hemilasius),highlighting the electro-cution of 5 endangered saker Falcons(Falco cherrug).By contrast,we only recorded 8 individuals of 5 species collid-ing with wires,the most affected being Pallas’s sandgrouse(syrrhaptes paradoxus).About 76.1%of sampled poles had some mitigation *** these,96.6%were brush perch deflectors and 3.4%rotating-mirrors perch *** found differences in electrocution rates among crossarm configurations,with the strain insulator with one jumper being the most ***,we found no correlation between bird abundance and electrocution rates,suggesting that some species are more sensitive to *** no differences in total bird electrocu-tion rates were detected between poles with and without perch deterrents,when bird size is considered,deterrents reduced the mortality rate of small birds,while they were ineffective for medium-sized

关键词： Collision Crossarm configuration Electrocution Electric infrastructures Perch deterrent Power line network Raptor

Combined cell-based therapy strategies for the treatment of Parkinson's disease:focus on mesenchymal stromal cells

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Neural Regeneration Research 2023年第3期18卷 478-484页

作者： Jannette Rodríguez-Pallares María garcía-Garrote juan A.Parga joséLuis Labandeira-garcía Laboratory of Cellular and Molecular Neurobiology of Parkinson´s Disease Research Center for Molecular Medicine and Chronic Diseases(CiMUS)IDISDepartment of Morphological SciencesUniversity of Santiago de CompostelaSantiago de CompostelaSpain Networking Research Center on Neurodegenerative Diseases(CIBERNED) MadridSpain

Parkinson’s disease is a neurodegenerative condition characterized by motor impairments caused by the selective loss of dopaminergic neurons in the substantia *** is an effective and well-tolerated dopamine replacement ***,levodopa provides only symptomatic improvements,without affecting the underlying pathology,and is associated with side effects after long-term ***-based replacement is a promising strategy that offers the possibility to replace lost neurons in Parkinson’s disease *** studies of transplantation of human fetal ventral mesencephalic tissue have provided evidence that the grafted dopaminergic neurons can reinnervate the striatum,release dopamine,integrate into the host neural circuits,and improve motor *** of the limiting factors for cell therapy in Parkinson’s disease is the low survival rate of grafted dopaminergic *** factors could cause cell death of dopaminergic neurons after grafting such as mechanical trauma,growth factor deprivation,hypoxia,and *** factors play an essential role in the survival of grafted ***,direct,timely,and controllable delivery of neurotrophic factors into the brain faces important *** types of cells secrete neurotrophic factors constitutively and co-transplantation of these cells with dopaminergic neurons represents a feasible strategy to increase neuronal *** this review,we provide a general overview of the pioneering studies on cell transplantation developed in patients and animal models of Parkinson’s disease,with a focus on neurotrophic factor-secreting cells,with a particular interest in mesenchymal stromal cells;that co-implanted with dopaminergic neurons would serve as a strategy to increase cell survival and improve graft outcomes.

关键词： brain repair cell replacement co-grafts dopaminergic neurons fetal ventral mesencephalic tissue mesenchymal stem cells neural grafting neural transplantation neuroblasts neurotrophic factors

software Vulnerabilities Overview:A Descriptive study

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Tsinghua science and Technology 2020年第2期25卷 270-280页

作者： Mario Calín sánchez juan Manuel Carrillo de Gea josé Luis Fernández-Alemán Jesús garcerán Ambrosio Toval the Department of Informatics and systems Faculty of Computer ScienceUniversity of Murcia

Computer security is a matter of great *** the last decade there have been numerous cases of cybercrime based on the exploitation of software *** fact has generated a great social concern and a greater importance of computer security as a *** this work,the most important vulnerabilities of recent years are identified,classified,and categorized individually.A measure of the impact of each vulnerability is used to carry out this classification,considering the number of products affected by each vulnerability,as well as its *** addition,the categories of vulnerabilities that have the greatest presence are *** on the results obtained in this study,we can understand the consequences of the most common vulnerabilities,which software products are affected,how to counteract these vulnerabilities,and what their current trend is.

关键词： descriptive study software security software vulnerabilities vulnerability databases

The immune system:uncharted pathways between senses and the brain

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Neural Regeneration Research 2024年第6期19卷 1173-1174页

作者： Noelia Casares Mar Cuadrado-Tejedor Ana garcía-Osta juan joséLasarte Immunology and Immunotherapy Program Centre for Applied Medical Research(CIMA)University of NavarraIDISNAPamplonaSpain Division of Gene Therapy for Neurological Disorders Centre for Applied Medical Research(CIMA)University of NavarraIDISNAPamplonaSpain Pathology Anatomy and Physiology DepartmentSchool of MedicineUniversity of NavarraIDISNAPamplonaSpain

Humans and animals use the classic five senses-sight,hearing,touch,smell,and taste-to detect and monitor their environment,with the sense of position and movement often referred to as the sixth *** perception of external signals through the senses is essential to an organism's survival,transmitting signals to the central nervous system(CNs)and prompting physiological changes in other biological *** addition to the direct effects of sense-induced mediators in the brain.

关键词： prompt system transmitting