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Assessing the Influence of Climate Extremes on Ecosystems and Human Health in Southwestern Amazon Supported by the PULSE-Brazil Platform

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American Journal of Climate Change 2016年第3期5卷 399-416页

作者： L. E. O. C. Aragão J. A. Marengo P. M. Cox R. A. Betts d. Costa N. Kaye L. Alves L. T. Smith I. F. A. Cavalcanti G. Sampaio L. O. Anderson M. Horta S. Hacon V. L. Reis P. A. M. Fonseca I. F. Brown divisao de Sensoriamento Remoto/Instituto Nacional de Pesquisas Espaciais (dSR/INPE) Sao Jose dos Campos Sao Paulo Brazil College of Life and Environment Sciences University of Exeter Exeter UK Centro Nacional de Monitoramento e Alertas aos desastres Naturais (CEMAdEN) Sao Jose dos Campos Sao Paulo Brazil College of Engineering Mathematics and Physical Sciences University of Exeter Exeter UK Met Office Hadley Centre Exeter UK Centro de Ciências do Sistema Terrestre/Instituto Nacional de Pesquisas Espaciais (CCST/INPE) Sao Jose dos Campos Sao Paulo Brazil School of Geographical Sciences University of Bristol Bristol UK Centro de Previsao de Tempo e Estudos Climáticos/Instituto Nacional de Pesquisas Espaciais (CPTEC/INPE) Sao José dos Campos Sao Paulo Brazil National Institute of Public Health/Oswaldo Cruz Foundation (FIOCRUZ)/ENSP Rio de Janeiro Brazil Secretaria de Estado de Meio Ambiente-Sema Prefeitura do Acre Rio Branco Brazil Instituto Nacional de Pesquisas da Amazonia (INPA) Manaus Brazil Universidade Federal do Acre Rio Branco Brazil

The complexity of multi-dimensional climate, environmental and human health information complicates bringing together scientists, civil society, and decision makers to provide adequate mitigation and adaptation options for the consequences of global environmental change. To provide an effective pathway to conciliate (integrate) these datasets, we present PULSE-Brazil as the Platform for Understanding Long-term Sustainability of Ecosystems and human health. The overarching aim of this paper is to focus on two study cases in the Brazilian state of Acre, 1) analyzing recent socio-environmental disasters such as the impacts of droughts and consequent increases in fire detections on the incidence of respiratory diseases, and 2) evaluating the impacts of temperature increases in combination with rainfall seasonality upon the incidence of dengue fever. Based on data available in PULSE-Brazil platform, we also aim to provide insights on the consequences of future climate variability on ecosystems and human health. Finally, we provide a discussion on the collaborative process between scientists and policymakers that defined the PULSE-Brazil platform specifications and datasets and propose a conceptual pathway for promoting the interaction between science and policy during the process of producing a tool that allows the understating of climate-relate processes. Our results clearly demonstrated that ecosystems are under increased fire risk in the future that will, in turn, affect the health of human populations. Moreover, humans are also exposed to critical dengue fever outbreaks with the projected increase in minimum temperatures. Therefore, minimizing the impacts of these potentially ascending socio-environmental problems is the first step for adapting to a changing climate in the Amazon region. We expect that PULSE-Brazil will serve not only as a technical tool for supporting governance, management, mitigation and long-term adaptation plans for climate impacts and natural d

关键词： Amazon droughts Human Health Fire Climate Change Vulnerability Adaptation Natural Hazard

β-淀粉样蛋白损害星形胶质细胞在阿尔茨海默病中对营养不良突触的吞噬作用

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神经损伤与功能重建 2021年第5期16卷 F0003-F0003页

作者： Maria V Sanchez-Mico Sebastian Jimenez Angela Gomez-Arboledas Clara Muñoz-Castro Carmen Romero-Molina Victoria Navarro Elisabeth Sanchez-Mejias Cristina Nuñez-diaz Raquel Sanchez-Varo Elena Galea joséC davila Marisa Vizuete Antonia Gutierrez Javier Vitorica 杜一星(编译) dpto.Bioquimica y Biologia Molecular Facultad de FarmaciaUniversidad de SevillaSevillaSpain Instituto de Biomedicina de Sevilla(IBiS)-Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla SevillaSpain Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas(CIBERNEd) MadridSpain department of Neurology Massachusetts General Hospital and Harvard Medical SchoolCharlestownMassachusettsUSA dpto.Biologia Celular Genetica y FisiologiaInstituto de Investigación Biomedica de Malaga-IBIMAFacultad de CienciasUniversidad de MalagaMalagaSpain Institut de Neurociències and departament de Bioquímica i Biologia Molecular Unitat de Bioquímica de MedicinaUniversitat Autònoma de BarcelonaBarcelonaSpain ICREA BarcelonaSpain. 不详

摘要在阿尔茨海默病(Ad)中,在β-淀粉样蛋白斑块周围发现了反应性星形胶质细胞和营养不良的神经突(异常的突触前元件)。笔者的前期研究已经表明,反应性星形胶质细胞会包裹、吞噬和降解APP小鼠以及Ad患者海马中营养不良的突触,但仅波及不... 详细信息

摘要在阿尔茨海默病(Ad)中,在β-淀粉样蛋白斑块周围发现了反应性星形胶质细胞和营养不良的神经突(异常的突触前元件)。笔者的前期研究已经表明,反应性星形胶质细胞会包裹、吞噬和降解APP小鼠以及Ad患者海马中营养不良的突触,但仅波及不到7%的营养不良神经突,这表明星形胶质细胞在Ad中的吞噬能力降低。本研究旨在通过分析原代星形胶质细胞培养物对分离突触(突触神经小体,SNs)吞噬和降解的能力来深入了解其潜在机制。SNs分别来自APP(包含营养不良性突触和β淀粉样肽)小鼠、Tau(包含AT8-和AT100-阳性磷酸化Tau)小鼠以及WT(对照)小鼠。我们发现与SNs-WT相比,星形胶质细胞的吞噬和降解能力在SNs-APP大大降低,但在AT8/AT100阳性的SNs-Tau却没有。在12月大的APP小鼠的海马中证实了星形胶质细胞吞噬能力的降低,因为只有(1.60±3.81)%的斑块状星形胶质细胞具有吞噬结构。

关键词：老年痴呆 β-淀粉样蛋白星形胶质细胞营养不良性突触小胶质细胞病理吞噬作用

团队成员的动机和领导者的行为对大学科学知识共享的影响

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国际行政科学评论（中文版） 2022年第2期 44-61页

作者：何塞·路易斯·巴列斯特罗斯—罗德里格斯佩亚·德·萨—佩雷斯娜塔莉·加西亚—卡波内尔费尔南多·马丁—阿尔卡扎冈萨罗·桑切斯—加尔迪杜明鸣(译) 王秋蕾(审校) 西班牙加那利群岛拉斯帕尔马斯大学西班牙加迪斯大学西班牙加迪斯大学商业管理系中国人事科学研究院绩效管理与考核奖惩研究室不详

本文旨在分析团队成员的动机和领导者的行为对研究项目组的学术人员之间进行知识共享的影响。为此,我们对西班牙几所大学项目组的678名学术研究人员进行了研究。采用层次回归分析来分析数据,结果表明,具有知识导向风格的领导者对其研究... 详细信息

本文旨在分析团队成员的动机和领导者的行为对研究项目组的学术人员之间进行知识共享的影响。为此,我们对西班牙几所大学项目组的678名学术研究人员进行了研究。采用层次回归分析来分析数据,结果表明,具有知识导向风格的领导者对其研究团队成员之间的知识共享有积极影响。然而,与预期相反的是,结果还显示,学术人员的外在动机对知识共享有负面影响,而内在动机没有影响。在考虑科学领域时,研究结果也是类似的。本文在学术研究的特定背景下对知识管理方面的文献作出了重要贡献。它揭示了以知识为导向的领导风格的重要性,因为它是研究团队中知识共享的一个关键决定因素。

关键词：人力资源管理知识共享领导力动机研究团队

Fungal diversity notes 111-252-taxonomic and phylogenetic contributions to fungal taxa

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Fungal diversity 2015年第6期75卷 27-274页

作者： Hiran A.Ariyawansa Kevin d.Hyde Subashini C.Jayasiri Bart Buyck K.W.Thilini Chethana dong Qin dai Yu Cheng dai dinushani A.daranagama Ruvishika S.Jayawardena Robert Lücking Masoomeh Ghobad-Nejhad Tuula Niskanen Kasun M.Thambugala Kerstin Voigt Rui Lin Zhao Guo-Jie Li Mingkwan doilom Saranyaphat Boonmee Zhu L.Yang Qing Cai Yang-Yang Cui Ali H.Bahkali Jie Chen Bao Kai Cui Jia Jia Chen Monika C.dayarathne Asha J.dissanayake Anusha H.Ekanayaka Akira Hashimoto Sinang Hongsanan E.B.Gareth Jones Ellen Larsson Wen Jing Li Qi-Rui Li Jian Kui Liu Zong Long Luo Sajeewa S.N.Maharachchikumbura Ausana Mapook Eric H.C.McKenzie Chada Norphanphoun Sirinapa Konta Ka Lai Pang Rekhani H.Perera Rungtiwa Phookamsak Chayanard Phukhamsakda Umpava Pinruan Emile Randrianjohany Chonticha Singtripop Kazuaki Tanaka Cheng Ming Tian Saowaluck Tibpromma Mohamed A.Abdel-Wahab dhanushka N.Wanasinghe Nalin N.Wijayawardene Jin-Feng Zhang Huang Zhang Faten A.Abdel-aziz Mats Wedin Martin Westberg joseph F.Ammirati Timur S.Bulgakov diogo X.Lima Tony M.Callaghan Philipp Callac Cheng-Hao Chang Luis F.Coca Manuela dal-Forno Veronika dollhofer Kateřina Fliegerová Katrin Greiner Gareth W.Griffith Hsiao-Man Ho Valerie Hofstetter Rajesh Jeewon Ji Chuan Kang Ting-Chi Wen Paul M.Kirk Ilkka Kytövuori James d.Lawrey Jia Xing Hong Li Zou Yi Liu Xing Zhong Liu Kare Liimatainen H.Thorsten Lumbsch Misato Matsumura Bibiana Moncada Salilaporn Nuankaew Sittiporn Parnmen AndréL.C.M.de azevedo Santiago Sujinda Sommai Yu Song Carlos A.F.de Souza Cristina M.de Souza-Motta Hong Yan Su Satinee Suetrong Yong Wang Syuan-Fong Wei Ting Chi Wen Hai Sheng Yuan Li Wei Zhou Martina Réblová Jacques Fournier Erio Camporesi J.Jennifer Luangsa-ard Kanoksri Tasanathai Artit Khonsanit donnaya Thanakitpipattana Sayanh Somrithipol Paul diederich Ana M.Millanes Ralph S.Common Marc Stadler Ji Ye Yan XingHong Li Hye Won Lee Thi T.T.Nguyen Hyang Burm Lee Eliseo Battistin Orlando Marsico Alfredo Vizzini Jordi Vila Enrico Ercole Ursula Eberhardt Giampaolo Simonini Hua-An Wen Xin-Hua Chen Otto Mie Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina Key Laboratory for Plant diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanChina Centre of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailan département Systématique et Evolution CP 39ISYEBUMR 7205 CNRS MNHN UPMC EPHEMuséum National d’Histoire Naturelle12 Rue BuffonF-75005 ParisFrance Institute of Plant and Environment Protection Beijing Academy of Agriculture and Forestry SciencesNo.9 of Shu Guang Hua Yuan Zhong LuHaidian DistrictBeijing 10097China Microbial drugs Helmholtz-Centre for Infection Research Inhoffenstrasse 738124 BraunschweigGermany Staatliches Museum für Naturkunde Stuttgart Rosenstein 1D-70191StuttgartGermany Institute of Microbiology Beijing Forestry UniversityPO Box 61Beijing 100083China State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesNo 31st West Beichen RoadChaoyang DistrictBeijing 100101China The Herbarium(ANdA) Universitas AndalasPadangSumatera Barat 25163Indonesia Botanischer Garten&Botanisches Museum Berlin Freie Universität BerlinKönigin-Luise-Straße 6-814195 BerlinGermany department of Biotechnology Iranian Research Organization for Science and Technology(IROST)P.O.Box 3353-5111Tehran ***Iran Jodrell Laboratory Royal Botanic GardensKew TW93DSUK Leibniz Institute for Natural Product Research and Infection Biology Jena Microbial Resource CollectionAdolf-Reichwein-Strasse 2307745 JenaGermany department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box:2455Riyadh 1145Saudi Arabia The United Graduate School of Agricultural Sciences Iwate University18-8 Ueda 3 ChomeMorioka 020-8550Japan Faculty of Agriculture and Life Sciences Hirosaki University3 Bunkyo-choHirosakiAomori 036-8561Japan department of Biological and Environmental Sciences University of GothenburgBox 461SE

This paper is a compilation of notes on 142 fungal taxa,including five new families,20 new genera,and 100 new species,representing a wide taxonomic and geographic *** new families,Ascocylindricaceae,Caryosporaceae and Wicklowiaceae(Ascomycota)are introduced based on their distinct lineages and unique *** new dothideomycete genera Pseudomassariosphaeria(Amniculicolaceae),Heracleicola,Neodidymella and Pseudomicrosphaeriopsis(didymellaceae),Pseudopithomyces(didymosphaeriaceae),Brunneoclavispora,Neolophiostoma and Sulcosporium(Halotthiaceae),Lophiohelichrysum(Lophiostomataceae),Galliicola,Populocrescentia and Vagicola(Phaeosphaeriaceae),Ascocylindrica(Ascocylindricaceae),Elongatopedicellata(Roussoellaceae),Pseudoasteromassaria(Latoruaceae)and Pseudomonodictys(Macrodiplodiopsidaceae)are *** newly described species of dothideomycetes(Ascomycota)are Pseudomassariosphaeria bromicola(Amniculicolaceae),Flammeascoma lignicola(Anteagloniaceae),Ascocylindrica marina(Ascocylindricaceae),Lembosia xyliae(Asterinaceae),diplodia crataegicola and diplodia galiicola(Botryosphaeriaceae),Caryospora aquatica(Caryosporaceae),Heracleicola premilcurensis and Neodidymella thailandicum(didymellaceae),Pseudopithomyces palmicola(didymosphaeriaceae),Floricola viticola(Floricolaceae),Brunneoclavispora bambusae,Neolophiostoma pigmentatum and Sulcosporium thailandica(Halotthiaceae),Pseudoasteromassaria fagi(Latoruaceae),Keissleriella dactylidicola(Lentitheciaceae),Lophiohelichrysum helichrysi(Lophiostomataceae),Aquasubmersa japonica(Lophiotremataceae),Pseudomonodictys tectonae(Macrodiplodiopsidaceae),Microthyrium buxicola and Tumidispora shoreae(Microthyriaceae),Alloleptosphaeria clematidis,Allophaeosphaeria cytisi,Allophaeosphaeria subcylindrospora,dematiopleospora luzulae,Entodesmium artemisiae,Galiicola pseudophaeosphaeria,Loratospora luzulae,Nodulosphaeria senecionis,Ophiosphaerella aquaticus,Populocrescentia forlicesenensis and Vagicola vagans(Phaeosphaeriaceae),Elon

关键词： Fungi Taxonomy New genus New species Phylogeny

2019年急性缺血性卒中患者早期管理指南:针对2018年急性缺血性卒中早期管理指南的更新美国心脏协会/美国卒中协会为医疗专业人员制定的指南

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国际脑血管病杂志 2020年第1期28卷 1-43页

作者： William J.Powers Alejandro A.Rabinstein Teri Ackerson Opeolu M.Adeoye Nicholas C.Bambakidis Kyra Becker jose Biller Michael Brown Bart M.demaerschalk Brian Hoh Edward C.Jauch Chelsea S.Kidwell Thabele M.Leslie-Mazwi Bruce Ovbiagele Phillip A.Scott Kevin N.Sheth Andrew M.Southerl deborah V.Summers Tirschwell 徐加平(译) 庄圣(译) 郭志良(译) 黄志超(译) 尤寿江(译) 刘慧慧(译) 张霞(译) 石际俊(译) 肖国栋(译) 曹勇军(译) 刘春风(译) 不详苏州大学附属第二医院神经内科卒中中心 215004

背景和目的本指南旨在在单个文件中为治疗急性动脉性缺血性卒中患者的临床医生提供最新的全面系列推荐意见。目标读者为院前急救人员、医生、综合医疗保健人员以及医院管理人员。本指南将取代2013年版急性缺血性卒中(acute ischemic str... 详细信息

背景和目的本指南旨在在单个文件中为治疗急性动脉性缺血性卒中患者的临床医生提供最新的全面系列推荐意见。目标读者为院前急救人员、医生、综合医疗保健人员以及医院管理人员。本指南将取代2013年版急性缺血性卒中(acute ischemic stroke,AIS)指南,同时也是对2018年版AIS指南的更新。方法写作组成员由美国心脏协会(American Heart Association,AHA)卒中委员会的科学声明监督委员会任命,代表各领域的医学专家。写作组成员不得对存在企业利益关系的相关议题进行讨论或投票。对2013年版AIS指南的更新最初于2018年1月发表,该版指南已经过AHA科学咨询与协调委员会以及AHA执行委员会批准。2018年4月,在删除部分推荐意见后,该指南的修订版在AHA网站上在线发表。要求写作组审查原始文件并在必要时进行修订。2018年6月,写作组提交了一份经过细微更改并纳入新近发表的重要随机对照试验(受试者数量>100名且具有AIS发病后至少90 d的临床转归)的文件。经过14位专家进行同行评议后,写作组根据同行评议专家的意见进行了适当修改。目前的最终文件已经过写作组全体成员(除非企业利益关系妨碍了成员投票)以及AHA管理机构批准。本指南采用了美国心脏病学学会/AHA 2015年推荐意见分类和证据级别标准以及新版AHA指南格式。结果本指南详细介绍了院前医疗、紧急和急诊评估、静脉和血管内治疗以及院内管理,包括在发病后最初2周内启用的二级预防措施。本指南支持院前和院内卒中医疗系统的一体化概念。结论本指南基于现有证据提供了总体推荐意见,用于指导治疗成年急性动脉性缺血性卒中患者的临床医生。然而,许多情况资料有限,迫切需要对AIS的治疗进行持续研究。

关键词： AHA科学声明重症监护疾病管理急诊医疗服务二级预防卒中治疗