检索结果-南通市图书馆

Murine model to study brain,behavior and immunity during hepatic encephalopathy

World Journal of Hepatology 2014年第4期6卷 243-250页

作者： Lindisley Ferreira Gomides Pedro Elias Marques Bruno Engler Faleiros Rafaela Vaz Pereira Sylvia Stella amaral Thais Reis Lage Gustavo Henrique Souza Resende Patricia Alves Maia Guidine Giselle Foureaux Fabíola Mara Ribeiro Fabiana Paiva Martins Marco Antonio Peliky Fontes Anderson josé Ferreira Remo Castro Russo Mauro Martins teixeira Márcio Flávio Moraes Antonio Lúcio teixeira Gustavo Batista Menezes Laboratório de Imunobiofotonica Department of MorphologyICBUFMGBelo Horizonte 31270-901Brazil School of Medicine UFMGBelo Horizonte 31270-901Brazil Department of Physiology ICBUFMGBelo Horizonte 31270-901Brazil Department of Morphology UFMGBelo Horizonte 31270-901Brazil Department of Biochemistry and Immunology UFMGBelo Horizonte 31270-901Brazil

AIM:To propose an alternative model of hepatic encephalopathy(HE) in mice,resembling the human features of the ***:Mice received two consecutive intraperitoneal injections of thioacetamide(TAA) at low dosage(300 mg/kg).Liver injury was assessed by serum transaminase levels(ALT) and liver histology(hematoxylin and eosin).Neutrophil infiltration was estimated by confocal liver intravital *** was evaluated using prolonged prothrombin and partial thromboplastin *** parameters were measured through tail *** levels were quantified in serum and brain ***(EEG) and psychomotor activity score were performed to show brain *** edema was evaluated using magnetic resonance ***:Mice submitted to the TAA regime developed massive liver injury,as shown by elevation of serum ALT levels and a high degree of liver *** intense hepatic neutrophil accumulation occurred in response to TAA-induced liver *** led to mice mortality and weight loss,which was associated with severe ***,TAA-treated mice presented with increased serum and cerebral levels of ammonia,in parallel with alterations in EEG spectrum and discrete brain edema,as shown by magnetic resonance *** agreement with this,neuropsychomotor abnormalities ensued 36 h after TAA,fulfilling several HE features observed in *** this context of liver injury and neurological dysfunction,we observed lung inflammation and alterations in blood pressure and heart rate that were indicative of multiple organ dysfunction ***:In summary,we describe a new murine model of hepatic encephalopathy comprising multiple features of the disease in humans,which may provide new insights for treatment.

关键词： Hepatic encephalopathy Liver injury Thioacetamide Neurological dysfunction Neuropsychomotor abnormalities Intracranial hypertension Cerebral herniation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Influence of Bed Geometry on the Drying of Skimmed Milk in a Spouted Bed

引用

Advances in Chemical Engineering and Science 2015年第4期5卷 447-460页

作者： Maisa Tonon Bitti Perazzini Fábio Bentes Freire josé teixeira Freire Department of Chemical Engineering Federal University of S&atildeo Carlos S&atildeo Carlos Brazil

In this present work, the fluidynamic and drying process of skimmed milk in conical and conical-cylindrical spouted bed was analyzed as a function of different bed geometry and operating conditions. It used three internal cone angles (45°, 60° and 75°), different loads of inert particles (1.50, 3.00 and 4.50 kg) and a fixed static bed height (20.50 cm). Polyethylene particles of 4.38 mm of diameter and 930.50 ± 0.3 kg/m3 of specific mass were used as inert particles. An artificial neural network model was trained to predict the peak pressure drop and the minimum spout velocity from an experimental data bank. The experimental results showed a significant effect of geometric characteristics of the bed on fluidynamics parameters. It was also observed for the operating conditions that conical spouted bed and cone angle of 45° were more suitable for drying skimmed milk. The neural network provided predictions in good agreement with experimental data.

关键词： Cone Angle Bed Geometry Bed Configuration Inert Particles Neural Network

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Antibacterial enhancement of antibiotic activity by Enterolobium contortisiliquum(Vell.)Morong

引用

Asian Pacific Journal of Tropical Biomedicine 2017年第10期7卷 945-949页

作者： Zildene de Sousa Silveira Nair Silva Macêdo Thiago Sampaio de Freitas Ana Raquel Pereira da Silva Joycy Francely Sampaio dos Santos Maria Flaviana Bezerra Morais-Braga josé Galberto Martins da Costa Raimundo Nonato Pereira teixeira Jean Paul Kamdem Henrique douglas Melo Coutinho Francisco Assis Bezerra da Cunha Laboratorio de Bioprospeccao do Semioarido Universidade Regional do CaririCratoBrazil Laboratorio de Microbiologia e Biologia Molecular Universidade Regional do CaririCratoBrazil Laboratorio de Pesquisas de Produtos Naturais Universidade Regional do CaririCratoBrazil Departamento de Ciencias biologicas Universidade Regional do Cariri-URCACratoCEP:63105-000Brazil Programa de Pos-graduacao em Bioprospeccao Molecular Universidade Regional do Cariri–URCACratoBrazil

Objective: To identify the main chemical classes of compounds from aqueous extract of Enterolobium contortisiliquum(E. contortisiliquum) seed bark and to evaluate its antibacterial activity, as well as its potential to increase the activity of antibiotics against strains of Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia ***: Different classes of compounds in the aqueous extract of E. contortisiliquum were evaluated based on the visual changes in the coloration and the formation of precipitate after the addition of specific reagents. The antibacterial activity of the extract and its potential to increase of antibiotic activity of antibiotics drugs, gentamicin and norfloxacin was determined by using the microdilution ***: Our results demonstrated that the following secondary metabolites were presented in E. contortisiliquum seed bark: flavones, flavonols, xanthones, flavononols,chalcones, aurones, flavones and catechins. The extract itself had very low antibacterial activity against all bacterial strains tested(MIC ≥ 1024 μg/m L), but there was an increase in the antibiotic activity of gentamicin and norfloxacin when combined in the subinhibitory concentration(i.e., MIC/8).Conclusions: Our data suggests that E. contortisiliquum seed bark may be an alternative source for new drugs with the potential to increase antibiotic activity against different strains of bacteria.

关键词： Antibiotic activity Enhancement Synergism Chemical compounds Bioactivity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Quantitative analysis of trigonelline in some Annona species by proton NMR spectroscopy

引用

Natural Products and Bioprospecting 2013年第4期3卷 158-160页

作者： Alan Rodrigues teixeira MACHAdo Gisele Avelar LAGE Felipe da Silva MEDEIROS josé Dias de Souza FILHO Lúcia Pinheiro Santos PIMENTA Departamento de Química ICExUniversidade Federal de Minas GeraisBelo HorizonteMinas Gerais31270-901Brasil

A quantitative ^(1)H NMR method(qHNMR)was used to measure the trigonelline content in the leaves of six species of the Annona *** methodology employed compared the intensities of the signals at δ9.14(H-2)andδ0.00,the internal standard TSP-d_(4).This measuring method was able to establish the concentration of trigonelline in the range from 0.67 to 10.04 mg·g^(-1) depending on the investigated extract.

关键词： trigonelline Annona quantitative^(1)H NMR

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Childhood trauma and factors associated with depression among inpatients with cardiovascular disease

引用

World Journal of Psychiatry 2017年第2期7卷 106-113页

作者： Felipe josé Nascimento Barreto Frederico Duarte Garcia Paulo Henrique teixeira Prado Paulo Marcos Brasil Rocha Nádia Souza Las Casas Felipe Barbosa Vallt Humberto Correa Maila Castro Lourenco Neves Department of Mental Health Federal University of Minas Gerais Postgraduation Program in Molecular Medicine School of Medicine Federal University of Minas Gerais Molecular Medicine National Institute of Science and Technology Avenida Alfredo Balena Federal University of Minas Gerais Hospital das Clínicas Federal University of Minas Gerais

AIM To identify factors associated with depressive symptoms among inpatients with cardiovascular disease(CVD). METHODS This is a cross-sectional study performed in a subsample of a large cross-sectional research that investigated affective disorders and suicide behaviour among inpatients hospitalized in non-surgical wards of the University Hospital of the Federal University of Minas Gerais from November 2013 to October 2015. Sociodemographic and clinical data were obtained through a structured interview and medical record review. Depression was assessed by the depression subscale of the Hospital Anxiety and Depression Scale, with scores ≥ 8 considered as positive screening for depression. We used the Fagestr?m Test for Nicotine Dependence to characterize nicotine dependence. For assessing resilience and early-life trauma, we used the raw scores of the Wagnild and Young Resilience Scale and Childhood Trauma Questionnaire, *** At endpoint, we included 137 subjects. Thirty-eight(27.7%) subjects presented depressive symptoms and nine(23.7%) of those were receiving antidepressant treatment during hospitalization. The female sex; a lower mean educational level; a greater prevalence of previous suicide attempts; a higher level of pain; a higher prevalence of family antecedents of mental disorders; a lower resilience score; and higher childhood trauma score were the factors significantly associated with screening positive for major depression(P < 0.05). Multivariate analysis demonstrated that the factors independently associated with the depressive symptoms were a higher childhood trauma severity(OR = 1.06; P = 0.004); moderate to severe nicotine dependence(OR = 8.58; P = 0.008); and the number of previous hospital admissions(OR = 1.11; P = 0.034). The obtained logistic model was considered valid, indicating that the three factors together distinguished between having or not depressive symptoms, and correctly classified 74.6% of individuals in the ***

关键词： Inpatients Depression Cardiovascular disease Depressive symptoms General hospital

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Potential of Activated Carbon in the Treatment of Water for Human Consumption, a Study of the State of the Art and Its Techniques Used for Its Development

引用

Advances in Bioscience and Biotechnology 2021年第6期12卷 143-153页

作者： Adenes teixeira Alves Dimas josé Lasmar Ires Paula de Andrade Miranda Jamal da Silva Chaar Jardson dos Santos Reis Federal University of Amazonas-UFAM Manaus Amazonas Brazil National Institute for Amazon Research (INPA) Manaus Amazonas Brazil

This review article addresses the use of biological activated carbon in water treatment and its techniques for its development, with the premise of analyzing the potential of Activated Carbon (AC) in the treatment of water for human consumption. For this end, it aims to identify the techniques used for the production of AC, use and its benefits, production from vegetable waste for water treatment. Activated carbon has the ability to selectively collect gases, liquids and impurities inside its pores, which is the reason it is widely used in filtration systems and for that the treatment of water, the coal fulfills the function of adsorbent, retaining in its pores certain types of impurities: large particles that cause undesirable color, taste or odor in the water. In the treatment of effluents, coal is used for clarification, deodorization and purification of effluents.

关键词： Activated Carbon Water Treatment Techniques Used

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Feasibility Study of a Hydro PV Hybrid System Operating at a Dam for Water Supply in Southern Brazil

引用

Journal of Power and Energy Engineering 2015年第9期3卷 70-83页

作者： Luis E.teixeira Johan Caux Alexandre Beluco Ivo Bertoldo joséAntonio S.Louzada Ricardo C.Eifler Instituto de Pesquisas Hidráulicas Universidade Federal do Rio Grande do SulPorto AlegreBrazil Ecole Nationale Superieure de l’Energie l’Eau et l’EnvironnementGrenoble INPGrenobleFrance Companhia Riograndense de Saneamento Santa MariaBrazil Companhia Estadual de Energia Elétrica Salto do JacuíBrazil

Dams for water supply usually represent an untapped hydroelectric potential. It is a small energetic potential, in most situations, usually requiring a particular solution to be viable. The use of pumps as power turbines often represents an alternative that enables the power generation in hydraulic structures already in operation, as is the case of dams in water supply systems. This potential can be exploited in conjunction with the implementation of PV modules on the water surface, installed on floating structures, both operating in a hydro PV hybrid system. The floating structure can also contribute to reducing the evaporation of water and providing a small increase in hydroelectric power available. This paper presents a pre-feasibility study for implementation of a hydroelectric power plant and PV modules on floating structures in the reservoir formed by the dam of Val de Serra, in southern Brazil. The dam is operated to provide drinking water to about 60% of the population of the city of Santa Maria, in the state of Rio Grande do Sul, in southern Brazil. The pre-feasibility study conducted with Homer software, version Legacy, indicated that the hydroelectric plant with a capacity of 227 kW can operate together with 60 kW of PV modules. This combination will result (in one of the configurations considered) in an initial cost of USD$ 1715.83 per kW installed and a cost of energy of USD$ 0.059/kWh.

关键词： Hydro PV Hybrid System PV Floating Cover Water Supply Dam Software Homer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Helicobacter pylori infection: Host immune response, implications on gene expression and microRNAs

引用

World Journal of Gastroenterology 2014年第6期20卷 1424-1437页

作者： Aline Cristina Targa Cadamuro Ana Flávia teixeira Rossi Nathália Maciel Maniezzo Ana Elizabete Silva Department of Biology UNESP-So Paulo State University Campus So José do Rio Preto

Helicobacter pylori(H. pylori) infection is the most common bacterial infection worldwide. Persistent infection of the gastric mucosa leads to inflammatory processes and may remain silent for decades or progress causing more severe diseases, such as gastric adenocarcinoma. The clinical consequences of H. pylori infection are determined by multiple factors, including host genetic predisposition, gene regulation, environmental factors and heterogeneity of H. pylori virulence factors. After decades of studies of this successful relationship between pathogen and human host, various mechanisms have been elucidated. In this review, we have made an introduction on H. pylori infection and its virulence factors, and focused mainly on modulation of host immune response triggered by bacteria, changes in the pattern of gene expression in H. pylori-infected gastric mucosa, with activation of gene transcription involved in defense mechanisms, inflammatory and immunological response, cell proliferation and apoptosis. We also highlighted the role of bacteria eradication on gene expression levels. In addition, we addressed the recent involvement of different microRNAs in precancerous lesions, gastric cancer, and inflammatory processes induced by bacteria. New discoveries in this field may allow a better understanding of the role of major factors involved in the pathogenic mechanisms of H. pylori.

关键词： Helicobacter pylori Inflammation Virulence factors Immune response Gastric lesions Gastric cancer Gene expression MicroRNAs

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Proposition of a Tool to Adjust the Inspired Oxygen Fraction in Anesthesia Devices during Prolonged Mechanical Ventilation in COVID-19 Patients

引用

Open Journal of Anesthesiology 2021年第10期11卷 299-305页

作者： Plínio de Oliveira Holanda Nely Marjollie Guanabara teixeira Reis josé Carlos R. Nascimento Felipe Paiva Alencar Marilman Maciel Benício Department of Anesthesia Dr. Jose Frota Institute Fortaleza Brazil Unichristus University Fortaleza Brazil Department of Anesthesia Fortaleza General Hospital Fortaleza Brazil Laboratory of the Biology of Tissue Healing Ontogeny and Nutrition Department of Morphology and Institute of Biomedicine School of Medicine Federal University of Ceara Fortaleza Brazil Department of Computer Engineering Ceara State University Fortaleza Brazil

The COVID-19 pandemic has had a major impact on health care services, leading to a breakdown in public and private health systems worldwide. A major challenge was the scarcity of mechanical ventilators, which resulted in the use of anaesthesia devices for this purpose. However, they are quite different from mechanical ventilators used in Intensive Care Units and some adaptations, such as the use of high flow to reduce CO2 rebreathing, were necessary to ensure patient safety. The objective of this study was to present a mathematical formula and develop a tool that can be used to adjust the flow of oxygen and air in flow metres of anaesthesia devices that do not have oxygen analysers or these analysers are not operational. A literature review was conducted using the main health databases and libraries as research sources: PubMed, Virtual Health Library (VHL), SciELO, and Cochrane. The review included studies published in English, Spanish, and Portuguese. Animal studies were excluded. A total of 11 references were included to support this article.

关键词： Anaesthesia Ventilator Intensive Care Unit FiO2 Fresh Gas Flow Webpage

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

护理干预促进慢性呼吸困难患者自我管理的研究进展:整合性综述

引用

International Journal of Nursing Sciences 2024年第2期11卷 241-257,I0003页

作者： Helga Rafael Henriques Andreia Correia Tatiana Santos jose Faria Diana Sousa Joana Portela Joana teixeira Nursing School of Lisbon LisbonPortugal CIDNUR-Nursing Research Innovation and Development Centre of LisbonLisbonPortugal Unidade de Hemodi-alise de Torres Vedras-Nephrocare Torres VedrasPortugal Unidade de Cuidados Continuados na AMETIC Torres VedrasPortugal Unidade Local de Saúde Sao jose Cardiology DepartmentLisbonPortugal Unidade Local de Saúde da Arrabida General Surgery DepartmentSetúbalPortugal

目的旨在通过系统综述,确定针对复杂慢性病患者增强自我管理的干预措施,以改善慢性呼吸困难,为护理人员促进该类人群的自我管理提供依据。方法2023年12月,系统检索Medline、Scopus、Web of Science、CINAHL、Cochrane图书馆和乔安娜布... 详细信息

目的旨在通过系统综述,确定针对复杂慢性病患者增强自我管理的干预措施,以改善慢性呼吸困难,为护理人员促进该类人群的自我管理提供依据。方法2023年12月,系统检索Medline、Scopus、Web of Science、CINAHL、Cochrane图书馆和乔安娜布里格斯研究所(Joanna Briggs Institute,JBI)循证实践数据库。对纳入研究进行数据提取和综合,研究人员采用Rayyan文献管理软件筛选标题及摘要,并依据JBI研究质量评估工具进行方法学质量评估。结果共纳入18项研究。这些研究探讨了针对慢性呼吸困难的各种干预措施,包括药物干预(氧气疗法和吸入疗法)和非药物方法(教育计划、呼吸练习、液体摄入管理、身体感知技术、同伴支持、情商培训和网络应用程序的使用)。这些干预措施减轻了患者情绪困扰,可以使患者在自我管理方面变得独立自主。结论促进复杂慢性病患者对慢性呼吸困难的自我管理需要采取综合方法,但目前研究中没有充分考虑到针对患者行为改变的干预措施,需要进一步开展相关研究完善干预措施。

关键词：慢性疾病呼吸困难护理病人自我管理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：