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Major Phenolics in Yerba Mate Extracts (<i>Ilex paraguariensis</i>) and Their Contribution to the Total Antioxidant Capacity

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Food and Nutrition Sciences 2013年第8期4卷 154-162页

作者： Lorena Deladino Aline Schneider Teixeira Mario Reta antonio D. Molina García Alba S. Navarro Miriam N. Martino Centro de Investigación y Desarrollo en Criotecnología de Alimentos (CIDCA CONICET-UNLP) La Plata Argentina Centro de Investigación y Desarrollo en Criotecnología de Alimentos (CIDCA CONICET-UNLP) La Plata Argentina Facultad de Ingeniería Universidad Na- cional de La Plata (UNLP) La Plata Argentina. ICTAN Instituto de Ciencia y Tecnología de Alimentos y Nutrición CSIC José Antonio Novais 10 Madrid Spain Lab. de Separaciones Analíticas División Química Analítica Fac. Cs. Exactas (UNLP) La Plata Argentina

Yerba mate (Ilex paraguariensis) is an indigenous crop which is highly consumed as an infusion in the South American subtropical forest. It has a high concentration of antioxidant substances, providing health benefits and helping to prevent diseases. The objectives of this work were to characterize an aqueous yerba mate extract by spectrophotometric and chromatographic (HPLC) methods and to study the effect of the freeze-drying process on the polyphenols profile and antioxidant activity, determined by a novel method. An aqueous extract was obtained and lyophilized to obtain a yerba mate powder with antioxidant properties. The extracts showed a high polyphenol content, determined by Folin-Ciocalteau and HPLC, and a high antioxidant activity towards the DPPH· radical and after the recently developed method of photochemiluminescence. A linear correlation was found between Folin-Ciocalteau and DPPH methods for lyophilized samples. HPLC analysis allowed determining antioxidant components like rutin, caffeine and chlorogenic acid. Lyophilization caused a decrease in total polyphenol content and antiradical activity of the extracts and this fact was mainly attributed to changes in the chlorogenic acid related compounds and rutin structures, after their photochemiluminescence data. The photoluminiscent method proves to be an advantageous approach for antioxidant capacity determination.

关键词： Yerba Mate Natural Antioxidants Freeze Drying DPPH HPLC PCL

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减缩剂对减少混凝土塑性收缩裂缝的影响

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膨胀剂与膨胀混凝土 2009年第4期 7-12页

作者： josé Mora-Ruacho Ravindra Gettu antonio Aguado 贾福杰

暴露在高蒸发速率环境下的新拌混凝土很容易产生塑性收缩裂缝,特别是表面积与体积的比率很大的时候,目前的研究都证明了,减少拌合水的表面张力是减少塑性裂缝的一种很有效的办法。我们将传统混凝土和高强混凝土掺加超塑化剂和减缩剂,在... 详细信息

暴露在高蒸发速率环境下的新拌混凝土很容易产生塑性收缩裂缝,特别是表面积与体积的比率很大的时候,目前的研究都证明了,减少拌合水的表面张力是减少塑性裂缝的一种很有效的办法。我们将传统混凝土和高强混凝土掺加超塑化剂和减缩剂,在塑性阶段暴露干燥,测量毛细孔压、沉降、内部温度和蒸发速率,结果显示减缩剂对减少混凝土甚至是高强混凝土的塑性裂缝都是很有效的,这主要由于蒸发速率减少,原因是孔中弯液面的发展导致毛细管压的峰值出现延迟和较低的沉降率。

关键词：干缩新拌混凝土耐久性收缩外加剂

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Scope of translational medicine in developing boroncontaining compounds for therapeutics

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World Journal of Translational Medicine 2017年第1期6卷 1-9页

作者： Ana Karen García-ávila Eunice Dalet Farfán-García Juan Alberto Guevara-Salazar josé Guadalupe Trujillo-Ferrara Marvin antonio Soriano-Ursúa Department of Biochemistry and Section of Post Graduate Studies and Research Escuela Superior de MedicinaInstituto Politécnico Nacional Department of Physiology and Section of Post Graduate Studies and Research Escuela Superior de MedicinaInstituto Politécnico Nacional

The ubiquitousness of naturally occurring boron-containing compounds(BCCs) has led to their constant contact with ***,many synthetic BCCs have been elaborated for a broad spectrum of purposes,especially boric,boronic and borinic *** BCCs were once employed primarily as antiseptics and later as antibiotics,they have become an increasingly relevant therapeutic ***,this potential of BCCs has been drastically limited due to some unfortunate intra-hospital accidents in the 1940 s and 1950 *** increasing use of BCCs as insecticides,antimicrobials,and other agents is providing new insights into their role in the physiology of several living species and in the pathophysiology of *** is becoming clear that BCCs act through a wide range of mechanisms,as do their corresponding boron-free *** comparing BCCs and similar boron-free compounds,in many cases the former show advantages in the medical *** current minireview focuses on how BCCs have been developed by means of translational medicine,a process connecting biomedical research with clinical *** process of discovery is currently in an exponential stage.

关键词： Boron Boron-containing compounds Drug development Toxicity Medicinal chemistry Pharmacology

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Decomposition of the interaction of common black bean group genotypes with the environment

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Agricultural Sciences 2013年第12期4卷 683-688页

作者： Paula Pereira Torga Patrícia Guimarães Santos Melo Helton Santos Pereira Luis Cláudio de Faria Maria joséDel Peloso Leonardo Cunha Melo Universidade Federal de Goiás Escola de Agronomia e Engenharia de AlimentosGoianiaBrazil Embrapa Arroz e Feijao Santo Antonio de GoiásBrazil

The purpose of this paper was to assess which environmental factor(s) (location, sowing season or years) in the common black bean genotypes interaction was more expressive and to verify the existence of genotypes with broad and/or specific adaptations to sowing season. Data of grain yield of thirteen genotypes were tested in twelve trials of value of cultivation and use during 2003 and 2004 in the south-central region of Brazil. Analyses of variance were performed with the decomposition of genotypes × environments interaction, which allowed a partial isolation of factors, and subsequently, eight trials were used which allowed a complete isolation of factors. The most important interactions were genotypes × years (R2 = 2.5%) and genotypes × locations (R2 = 1.9%), while genotypes × sowing seasons was the least important (R2 = 1.4%). Thus, it is more important to evaluate the genotypes in different locations and years than at different seasons. Most genotypes showed wide adaptation, but some lines showed strong specific adaptation.

关键词： Phaseolus vulgaris Indication of Cultivars Adaptability

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Process Mineralogy of Lateritic Nickel Ore

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矿物学报 2013年第S1期33卷 17-17页

作者： Daniel Uliana M.Manuela M.Lé Tassinari Henrique Kah Marco antonio Angora University of Sao Paulo Polytechnic SchoolMining and Petroleum Engineering Department Av.Prof.Mello Mores2373SAO PAULOSPBrazil Votorantim Metais Nickel Business Unit Av.Dr.José Artur Nova1309SAO PAULOSPBrazil

This paper presents a methodology for studying low grade lateritic nickel ore, which usually presents complex mineralogy, with widespread nickel in several mineral phases. The study is focused on determining the mineralogy and the distribution of nickel in the bearing minerals. Laboratory assays comprise homogenization, sampling and particle size analysis. Chemical analyses by X-ray fluorescence are performed in all fractions sizes, while mineralogical assessments by X-ray diffraction are carried out for head sample. The mineralogical composition of the samples and the partition of main elements in the bearing minerals are assayed by size fraction through automated image analysis software (MLA) coupled to a scanning electron microscope (SEM). The chemical compositions of the several minerals identified in MLA are determined during systematic observations on SEM with energy dispersive spectrometer (EDS).

关键词： nickel ore process mineralogy automated mineralogy image analysis

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Inflammatory pseudotumour of the spleen associated with splenic tuberculosis

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World Journal of Gastrointestinal Surgery 2014年第12期6卷 248-252页

作者： Maria Isabel Prieto-Nieto Juan Pedro Pérez-Robledo Beatriz Díaz-San Andrés Manuel Nistal josé antonio Rodríguez-Montes Department of General and Digestive Surgery La Paz University Hospital Paseo de la Castellana 28046 Madrid Spain Department of Pathology La Paz University Hospital Paseo de la Castellana 28046 Madrid Spain

Inflammatory pseudotumor(IPT) of the spleen is an uncommon entity with an uncertain aetiology. Inflammatory pseudotumors present diagnostic difficulties because the clinical and radiological findings tend to suggest a malignancy. The symptoms include weight loss, fever, and abdominal pain. Most cases of splenic IPT present solitary relatively large well circumscribed masses on imaging. The diagnosis in the majority of the cases is made after histopathologic study of splenectomy specimens. The IPTs that occur in the spleen and liver are typically associated with Epstein-Barr virus. Thirtyseven percent of all new cases of active tuberculosis infection are extrapulmonary tuberculosis and tuberculous lymphadenitis the most commonly occurring form of extrapulmonary tuberculosis. We report the case of an inflammatory pseudotumor of the spleen associated with splenic tuberculous lymphadenitis in a 50-year-old female patient who was preoperatively diagnosed with a malignant spleen tumour based on her history of breast of carcinoma.

关键词： splenic spleen tuberculosis radiological malignancy splenectomy tumour solitary majority tuberculous

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Cellular Forms in Cultivation in Suspension of Bougainvillea glabra Choisy Variety Surprise

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Journal of Agricultural Science and Technology(A) 2018年第4期8卷 203-211页

作者： Christian Marely Rodriguez-Salazar josé Roman-Reynosa Sandra Victoria Avila-Reyes Franklin Loring-Younce antonio Ruperto Jiménez-Aparicio Silvia Evangelista-Lozano Centro de Desarrollo de Productos Bióticos del Instituto Politécnico Nacional (CEPROBI-IPN) Carretera Yautepec-JojutlaKm 6calle CEPROBI no. 8Colonia San IsidroC.P. 62731YautepecMorelosMéxico Tecnológico de Zacatepec del Instituto Nacional de México Calzada Tecnológico 27Col. Plan de AyalaC.P. 62780Zacatepec de HidalgoMorelosMéxico CONACyT-Instituto Politécnico Nacional (CEPROBI-IPN) Carretera Yautepec-JojutlaKm 6calle CEPROBI No. 8Colonia San IsidroC.P. 62731YautepecMorelosMéxico School of Food Science Washington State UniversityPullmanWA 99164-6376USA

The objective of this work was to describe the predominant cell forms in the phases of growth kinetics in a suspension culture of the Bougainvillea glabra Choisy variety *** in suspension with Murashige and Skoog(MS)basal culture medium were supplemented with six different concentrations and combinations of vegetable growth regulator(VGR)of type auxin(2,4-D and NAA)and cytokinin(BAP)(0.2-5.3 mg/L)and a *** callus was obtained from leaf explants ex vitro to in vitro culture in solid MS medium using PhytagelTM as gelling agent to 2.2 g/L.A portion of callus(1.0 g)was used as cellular inoculum and grown under controlled conditions(50 mL,120 rpm,25°C and luminous intensity of 48μmol m2/s).The best treatment with significant differences(p≤0.05)were with a hormonal relation of 2:1 of BAP and NAA,respectively,with a fresh weight yield ranging from 1.7905 g to 5.8340 g,which represents around 70%.An adaptation phase was observed from day 0 to day 14 on the curve of fresh weight;an exponential phase at day 14 to day 19 and a declination phase at day *** forms in the adaptation phase were elongated cells,a few globular and a few with kidney *** the exponential phase,these cells formed small aggregates of globular *** the death phase,brown,elongated,damaged and fragmented cells were *** this data obtained it is possible to establish the subculture time in fresh medium.

关键词： Bougainvillea kinetics of cell growth in vitro culture

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Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

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Cellular & Molecular Immunology 2021年第9期18卷 2128-2139页

作者： Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos joséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez joséManuel Lomas Claudio Bueno Rosario Amaya joséantonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén joséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez E Clinical Unit of Infectious Diseases Microbiology and Preventive MedicineInstitute of Biomedicine of Seville(IBiS)Virgen del Rocío University HospitalCSICUniversity of SevilleSevilleSpain Department of Medical Biochemistry Molecular Biologyand ImmunologySchool of MedicineUniversity of SevilleSevilleSpain Pneumology Service Galicia Sur Health Research Instituto(IIS Galicia Sur)SERGAS-UVigoVigoSpain Infectious Diseases Unit Department of Internal MedicineComplexo HospitalarioUniversitario de VigoIIS Galicia SurSERGAS-UVigoVigoSpain Group of Virology and Pathogenesis Galicia Sur Health Research Institute(IIS Galicia Sur)-Complexo Hospitalario Universitario de VigoSERGAS-UVigoVigoSpain Unit of Infectious Diseases Microbiologyand Preventive MedicineVirgen del Rocío University HospitalSevilleSpain Institute of Biomedicine of Seville(IBiS) Virgen del Rocío University Hospital/CSIC/University of SevilleSevilleSpain Medico-Surgical Unit of Respiratory Diseases Virgen del Rocío University HospitalSevilleSpain Unit of Emergencies Virgen del Rocío University HospitalSevilleSpain Intensive Care Unit Virgen del Rocío University HospitalSevilleSpain Department of Medicine University of SevilleSevilleSpain Cardiology and Cardiovascular Surgery Unit Virgen del Rocío University HospitalSevilleSpain Rheumatology Unit Virgen del Rocío University HospitalSevilleSpain Internal Medicine Unit Virgen del Rocío University HospitalSevilleSpain Digestive and Hepatobiliary Unit Virgen del Rocío University HospitalSevilleSpain Neurology and Clinical Neurophysiology Unit Virgen del Rocío University HospitalSevilleSpain Endocrinology and Nutrition Unit Virgen del Rocío University HospitalSevilleSpain Urology and Nephrology Unit Virgen del Rocío University HospitalSevilleSpain Unit of Clinical Investigation and Clinical Trials Virgen del Rocío University HospitalSevilleSpain

Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity *** cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease *** this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory ***,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 ***,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were *** findings contribute to a better understanding of the immunological sequelae of COVID-19.

关键词： SARS-CoV-2 COVID-19 Dendritic cell Long-COVID

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Combining Ability and Heterosis in Corn Breeding Lines to Forage and Grain

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American Journal of Plant Sciences 2014年第6期5卷 845-856页

作者： Cesar Guerrero Guerrero Miguel A. Gallegos Robles josé Guadalupe Luna Ortega Ignacio Orona Castillo Cirilo Vázquez Vázquez Mario García Carrillo Alejandro Moreno Resendez Anselmo González Torres Catederatico de la Universidad Politécnica de la Región Laguna México Catederaticos de la UAAAAUL Torreon México Direccion General de Educación Tecnológica Industrial Torreón México Universidad Juárez del Estado de Durango Venecia Dgo México

This study was conducted in two stages, in 2006 the formation of cross, in the experimental field of the Universidad Autonoma Agraria antonio Narro Unidad Laguna (UAAANUL), and the evaluation of the same in 2007;at two locations with three environments, a locality was the experimental field of UAAANUL during spring and summer cycles and another location was the Niagara, Municipality of Aguascalientes, during the spring cycle. The genetic material used consisted of three groups of lines: the first group formed by four lines from the UAAANUL, the second group, two lines from INIFAP, and the third group, 10 lines of the International Center for Maize Improvement and Wheat (CIMMYT). The main objective was to estimate the effects of general combining ability (GCA) of the lines, and the specific combining ability (SCA) of their crosses and heterosis, to estimate its use in a breeding program. Estimates of general combining ability (GCA) and specific combining ability (SCA) were obtained using an analysis of line x line. To forage yield (FY), B-40 (16.84 t·ha-1) and AN-447 (1.54 t·ha-1) and to grain yield (GY), AN-388R (2.31 t·ha-1) had the greatest effect of GCA in both types of yield. The greatest effects of SCA for (FY) were cross AN-447XCML-264 (17.56 t·ha-1) and AN-388RXCML-319 (16.54 t·ha-1), in (GY) were cross AN-447XCML-315 (1.94 t·ha-1) and B-40XCML-319 (1.78 t·ha-1). For heterosis, higher value in forage yield was cross AN-447XCML-264 (20.7%), in grain yield, were B-40XCML-319 (27.1%) and B-32XCML-319 (22.1%) crosses. These results show that it is possible to structure a hybrid program using best lines from CIMMYT, INIFAP and UAAANUL.

关键词： Zea mays L. Hybrids Genetic Material Crosses SCA

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在 esophagogastroduodenoscopy 使用 lidocaine 的实用性与 propofol 表现在镇静下面

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World Journal of Gastrointestinal Endoscopy 2013年第5期5卷 231-239页

作者： Felipe de la Morena Cecilio Santander Carlos Esteban Beatriz de cuenca Juan antonio García Javier Sánchez Ricardo Moreno Endoscopy Unit Department of GastroenterologyHospital Universitario Infanta CristinaCP 28981 ParlaMadridSpain Department of Gastroenterology Hospital Universitario de la PrincesaCP 28006 MadridSpain Department of Anaesthesiology Hospital Universitario Infanta CristinaCP 28981 ParlaMadridSpain Department of Pharmacology Hospital Universitario Infanta CristinaCP 28981 ParlaMadridSpain

AIM:To determine whether topical lidocaine benefits esophagogastroduoduenoscopy(EGD) by decreasing propofol dose necessary for sedation or procedurerelated ***:The study was designed as a prospective,single centre,double blind,randomised clinical trial and was conducted in 2012 between January and May(NCT01489891).Consecutive patients undergoing EGD were randomly assigned to receive supplemental topical lidocaine(L;50 mg in an excipient solution which was applied as a spray to the oropharynx) or placebo(P;taste excipients solution without active substance,similarly delivered) prior to the standard propofol sedation *** propofol was administered as a bolus intravenous(iv) dose,with patients in the L and P groups receiving initial doses based on the patient’s American Society of Anaesthesiologists(ASA) classification(ASAⅠ-Ⅱ:0.50-0.60 mg/kg;ASA Ⅲ-Ⅳ:0.25-0.35 mg/kg),followed by 10-20 mg iv dose every 30-60 s at the anaesthetist’s *** signs,anthropometric measurements,amount of propofol administered,sedation level reached,examination time,and the subjective assessments of the endoscopist’s and anaesthetist’s satisfaction(based upon a four point Likert scale) were *** statistical tests were performed by the Stata statistical software suite(Release 11,2009;StataCorp,LP,College Station,TX,United States).RESULTS:No significant differences were found between the groups treated with lidocaine or placebo in terms of total propofol dose(310.7 ± 139.2 mg/kg per minute vs 280.1 ± 87.7 mg/kg per minute,P = 0.15) or intraprocedural propofol dose(135.3 ± 151.7 mg/kg per minute vs 122.7 ± 96.5 mg/kg per minute,P = 0.58).Only when the L and P groups were analysed with the particular subgroups of female,< 65-year-old,and lower anaesthetic risk level(ASA Ⅰ-Ⅱ) was a statistically significant difference found(L:336.5 ± 141.2 mg/kg per minute vs P:284.6 ± 91.2 mg/kg per minute,P = 0.03) for greater total propofol requirements).The total i

关键词： Lidocaine Propofol Esophagogastroduodenoscopy Sedation Adverse effects

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