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Hepatotoxicity induced by acute and chronic paracetamol overdose in children: Where do we stand?

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World Journal of Pediatrics 2017年第1期13卷 76-83页

作者： Hoi Yan Tong Nicolás Medrano Alberto Manuel Borobia joséAntonio Ruiz Ana María Martínez Julia Martín Manuel quintana Santos Garcfa Antonio jos6 Carcas Elena Ramirez Department of Clinical Pharmacology Hospital Universitario La PazIdiPAZSchool of MedicineUniversidad Autónoma de MadridMadridSpain Pediatric Emergency Department Hospital Universitario La PazIdiPAZMadridSpain General Emergency Department Hospital Universitario La PazIdiPAZMadridSpain

Background:There are few data Oll hepatotoxicity induced by acute or chronic paracetamol poisoning in the pediatric *** poisoning data can reveal the weakn嗍ofparacetamol poisoning management ***:We retrospectively studied the patients of less than 18 years old with measurable paracetamol levels,who were brought to the emergency department(ED)of La Paz University Hospital,Madrid,Spain,for suspected paracetamol overdoses between 2005 and 2010.

关键词： acute liver failure hepatotoxicity paracetamol poisoning

Determination of the Taxonomic Diversity of the Intertidal Fish Communities on the Pacific Coast of Baja California Sur, México from 2015-2019

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Open Journal of Marine Science 2022年第2期12卷 44-60页

作者： Jesús Eduardo Contreras Romero Emelio Barjau González Juan Manuel López-Viva josé ángel arm.nta quintana Javier Aguilar Parra Elvia Esthela Aispuro Felix Bruma Rachel Castillo-Rosas Departamento Académico de Ciencias Marinas y Costeras Universidad Autónoma de Baja California Sur La Paz B.C.S. Departamento Académico de Ciencia Animal y Conservación del Hábitat Universidad Autónoma de Baja California Sur La Paz B.C.S. Departamento Académico de Sistemas Computacionales Universidad Autónoma de Baja California Sur La Paz B.C.S.

The coastal areas of the Baja California peninsula are characterized mainly by rocky areas, where rock pools dominate as important coastal habitats because of the tide cycle, when the water is trapped during the low tide, forming the pools. Environmental parameters like temperature, salinity and dissolved oxygen of the water trapped in the pools are key factors for the flora and fauna that inhabit these areas, particularly during the warmer months when the mean values of these parameters are usually higher than the mean values of the sea surface. The aim of the present study was to determine the variation of the taxonomic diversity of the fish communities that inhabit the rock pools in the common land known as Conquista Agraria in the Pacific coast of Baja California Sur, México, from 2015 to 2019. A total of 59 visual censuses were carried out monthly during the second low tide of the full moon. Temperature, salinity, and dissolved oxygen showed variation throughout the study period, with two distinct seasons (warm and cold), which influenced the taxonomic diversity and taxonomic distinctness of the species recorded in the area. There was a higher diversity in the warmer months (summer) and years (2015 and 2016). In addition, according to the MDS analysis, 2017 and 2018 showed high similarity of species.

关键词： Rock Pools Intertidal Zone Taxonomic Diversity Taxonomic Distinctness

Determination of the Fish Community Structure of an Intertidal Rocky Zone of the Pacific Coast of Baja California Sur

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Open Journal of Marine Science 2022年第1期12卷 1-18页

作者： Laura E. Cota-Ortega Emelio Barjau-Gonzalez Juan Manuel López-Vivas josé Ángel arm.nta-quintana Javier Aguilar-Parra Elvia Esthela Aispuro-Felix Abril Karim Romo Piñera Departamento Académico de Ciencias Marinas y Costeras Universidad Autónoma de Baja California Sur La Paz B.C.S. Departamento Académico de Ciencia Animal y Conservación del Hábitat Universidad Autónoma de Baja California Sur La Paz B.C.S. Departamento Académico de Sistemas Computacionales Universidad Autónoma de Baja California Sur La Paz B.C.S.

The intertidal zone (also known as seashore) are transition areas between land and sea, that are greatly influenced by the tide cycle, therefore, environmental parameters, such as temperature and salinity, oscillate according to the periods in which these areas are exposed to air. Intertidal zones are highly diverse, which makes them key ecosystems for the development of sea life (both flora and fauna) exposed to drastic environmental change. The 59 visual censuses campaigns were carried out during the full moon of each month from 2015 to 2019. Temperature, salinity and dissolved oxygen were recorded during each visual census and showed variations between years. Temperature showed two distinct seasons, warm and cold. A total of 14,995 organisms were recorded, belonging to 30 species, 28 genera, 15 families, five orders and one class. Ecological indices like species richness (SR), Shannon-Wiener’s diversity (H') and Fisher’s alpha (α-Fisher) showed significant differences between years, 2015 and 2016 recorded as the most diverse years, while the lowest values were recorded in 2019. Therefore, fish communities of tide pools showed to be highly diverse, with 30 species recording similar relative abundances, and according to the BVI, only 11 species were dominant. Spatio-temporal variations of temperature, salinity and dissolved oxygen were highly correlated to changes in fish community structure, and the dominance of certain species, which are of great

关键词： Rockpools Ecological Indices Fish Community Structure Intertidal Zone

Variation of Density and Biomass of the Ichthyofauna Associated to Soft Bottoms of a Western Coastal Lagoon of B.C.S., Mexico

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Open Journal of Marine Science 2021年第4期11卷 169-186页

作者： Bruma Rachel Castillo Rosas Emelio Barjau González Juan Manuel López Vivas josé ángel arm.nta quintana Javier Aguilar Parra Rodolfo Daniel Acosta Guerrero Rogelio Esquivel Tiscareño Departamento Académico de Ciencias Marinas y Costeras Universidad Autónoma de Baja California Sur La Paz B.C.S. Departamento Académico de Ciencia Animal y Conservación del Hábitat Universidad Autónoma de Baja California Sur La Paz B.C.S. Departamento Académico de Sistemas Computacionales Universidad Autónoma de Baja California Sur La Paz B.C.S.

An analysis of the variation of the density and biomass of the fish communities of the lagoon of La Paz, Mexico was carried out from November 2016 to September 2017. A total of 2763 organisms were collected with a total biomass of 211,422.93 g in an area of 5022 m2, a density and biomass of 0.550 lnd/m2 and 44.091 g/m2. The site with the largest biomass was recorded in Zacatecas (11.179 g/m2) located north of the lagoon, while Grand Plaza recorded the lowest biomass (2.732 g/m2). Regarding the density, the maximum value was recorded in the site Yate Hundido, located northwest of the lagoon (0.129 lnd/m2) and the lowest was Las Palmas (0.036 lnd/m2) located north of the lagoon. The most abundant species was Diapterus peruvianus with 683 individuals and a biomass of 37,507.57 g. The physicochemical variables showed two seasons with significant change where we can observe higher temperatures in the summer (average of 27.45°C) and minimum in winter (average of 22.49°C). The Shannon-Weaver diversity index showed a difference (p = 0.050) between months, with the highest value recorded in April (H' = 2.133 bits/ind) and the lowest in June (H' = 1.041 bits/ind). The biomass and density values recorded in the lagoon were found to be associated with the spatio-temporal variation of temperature of the lagoon, as well as the resident and transitory species located in the area of study. In addition

关键词： Lagoon of La Paz Diversity Abundance Dominance

Use of recycled concrete aggregates in asphalt mixtures for pavements:A review

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Journal of Traffic and Transportation Engineering(English Edition) 2022年第5期9卷 725-741页

作者： Juan Gabriel Bastidas-Martínez Fredy Alberto Reyes-Lizcano Hugo Alexander Rondón-quintana Faculty of Engineering Universidad Piloto de ColombiaBogotáDC 110231Colombia Faculty of Engineering Pontificia Universidad JaverianaBogotáDC 110131Colombia Facultad del Medio Ambiente y Recursos Naturales Universidad Distrital Francisco Joséde CaldasBogotáDC 110131Colombia

Large quantities of natural aggregates(NA)are required in the manufacturing of asphalt mixtures for *** extraction of NA generates high environmental impacts that negatively affect environmental preservation and *** alternative materials obtained in construction and demolition processes in civil construction worked have been studies as possible replacements for NA,with the purpose of reducing these environmental *** foregoing study presents a state of knowledge review referring to the use of recycled concrete aggregates(RCA)when these are used in the manufacturing of asphalt mixtures(mainly hot-mix asphalt HMA type).Environmental aspects are presented,as well as possible benefits and limitations of using RCA as replacements for NA in asphalt ***,it is not possible to establish a behavior pattern,since the characteristics of the RCA are very heterogeneous and vary from the original source of the *** is highlighted from the literature that RCA has a wide potential for use in the manufacture of asphalt mixtures,since in most studies,the mixtures with these materials comply the quality requirements contemplated by the construction specifications,mainly in low-volume ***,based on the literature review,some recommendations and suggestions are presented for future research.

关键词： Recycled concrete aggregates Asphalt mixtures Mechanical properties Volumetric composition

Liver dysfunction and SARS-CoV-2 infection

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World Journal of Gastroenterology 2021年第26期27卷 3951-3970页

作者： Abraham Edgar Gracia-Ramos Joel Omar Jaquez-quintana Raúl Contreras-Omaña Moises Auron Department of Internal Medicine General HospitalNational Medical Center"La Raza"Instituto Mexicano del Seguro SocialMexico City 02990Mexico Gastroenterology Service and Department of Internal Medicine Faculty of MedicineUniversity Hospital"Dr.JoséE.González"Universidad Autónoma de Nuevo LeónMonterrey 64460Mexico Centro de Estudio e Investigación en Enfermedades Hepáticas y Toxicológicas(CEIHET) Pachuca 42184Mexico Departments of Hospital Medicine and Pediatric Hospital Medicine Cleveland ClinicClevelandOH 44195United States

Severe acute respiratory syndrome coronavirus 2 infection is the cause of coronavirus disease 2019(COVID-19),which predominantly affects the respiratory system;it also causes systemic and multi-organic *** damage is among the main extrapulmonary ***-19-associated liver injury is defined as any liver damage occurring during the disease course and treatment of COVID-19 in patients with or without pre-existing liver disease,and occurs in approximately one in five *** liver test results have been associated with a more severe course of COVID-19 and other complications,including *** linking COVID-19 to liver injury are *** consideration should be made for patients with pre-existing liver disease,such as metabolic dysfunction-associated fatty liver disease,chronic liver disease due to viral or autoimmune disease,liver transplant carriers,or cirrhosis,given the risk for more severe *** manuscript summarizes the current lines of evidence on COVID-19-associated liver injury regarding pathophysiology,clinical significance,and management in both patients with or without preexisting liver disease,to facilitate clinicians’access to updated information and patient ***,we mention the ideas and recommendations to be considered for future research.

关键词： SARS-CoV-2 Coronavirus COVID-19 Liver Liver diseases Liver failure Liver injury Cirrhosis

Taxonomic Distinctness of the Intertidal Fish Community on the Pacific Coast of Baja California Sur, México

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Open Journal of Marine Science 2019年第2期9卷 86-97页

作者： Emelio Barjau-González josé Ange arm.nta-quintana Juan Manuel López-Viva Eleonora Romero-Vadillo Departamento Académico de Ciencia Animal y Conservación del Hábitat Universidad Autónoma de Baja California Sur La Paz México Departamento Académico de Ciencias Marinas y Costeras Universidad Autónoma de Baja California Sur La Paz México Departamento Académico de Ciencia Animal y Conservación del Hábitat Universidad Autónoma de Baja California Sur La Paz México

The intertidal zone is a complex coastal area exposed to a wide variety of environmental factors. During low tide, rocky pools are exposed to air for several hours throughout the day, and environmental conditions such as temperature and salinity are highly variable. Fish communities that inhabit these tide pools are also exposed to environmental variability;therefore it is important to look at fish community structure in relation to important environmental factors such as temperature, salinity and dissolved oxygen on tide pools during spring tides, time of greater exposure to air. Therefore, the aim of the present study was to analyze the variation of the taxonomic distinctness of intertidal fish communities considering temperature, salinity and dissolved oxygen of the water that remains trapped in the tide pools during low tide. Visual census surveys were carried out monthly, from January to December 2015, in the intertidal zone of El Faro during spring tides on full moon days, when fluctuations of environmental variables are significant. Total extension of the census surveys was 156 × 5 m (780 m2). A total of 145 tide pools were sampled and divided in three groups (small, medium and large) according to size and depths that ranged from 20 to 45 cm. Temperature, salinity and dissolved oxygen fluctuate throughout the year of study. Thermal difference between open ocean and tide pools ranged from 3.5°C to 4.5°C. A total of 3757 organisms from 22 species, 12 families, four orders and one class were recorded. When comparing taxonomic distinctness and average taxonomic distinctness between months and tide pools of different sizes, values fell within the confidence intervals in the tunnel and were located close to the mean.

关键词： Taxonomic Distinctness Exposed Coast Climate Change

Subclinical abnormal glucose tolerance is a predictor of death in liver cirrhosis

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World Journal of Gastroenterology 2014年第22期20卷 7011-7018页

作者： Diego García-Compeán Joel Omar Jáquez-quintana Fernando Javier Lavalle-González josé Alberto González-González Linda Elsa Mu?oz-Espinosa Jesús Zacarías Villarreal-PérezEndocrinology Service and Department of Internal Medicine University Hospital "Dr. josé E. González" and Medical School Universidad Autónoma de Nuevo León Monterrey 64320 México Héctor J Maldonado-Garza Gastroenterology Service and Department of Internal Medicine University Hospital "Dr. José E. Gonzalez" and Medical SchoolUniversidad Autónoma de Nuevo LeónMonterrey 64320México Endocrinology Service and Department of Internal Medicine University Hospital "Dr. José E. González" and Medical SchoolUniversidad Autónoma de Nuevo LeónMonterrey 64320México Liver Unit University Hospital "Dr. José E. González" and Medical SchoolUniversidad Autónoma de Nuevo LeónMonterrey 64320México

AIM: To determine if subclinical abnormal glucose tolerance (SAGT) has influence on survival of non-diabetic patients with liver cirrhosis.

关键词： Diabetes mellitus Liver cirrhosis Oral glucose tolerance test Survival Glucose metabolism disorders

Functional Diversity of the Fish Community Associated to Soft-Bottoms in the Lagoon of La Paz B.C.S., México

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Open Journal of Marine Science 2020年第4期10卷 233-244页

作者： Hernandez-Villasana Carlos Samuel Barjau-González Emelio López-Vivas Juan Manuel arm.nta-quintana josé Angel Suárez-Villavicencio Jaime Departamento Académico de Ciencias Marinas y Costeras Universidad Autónoma de Baja California Sur La Paz B.C.S. México Departamento Académico de Ciencia Animal y Conservación del Hábitat Universidad Autónoma de Baja California Sur La Paz B.C.S. México Departamento Académico de Sistemas Computacionales Universidad Autónoma de Baja California Sur La Paz B.C.S. México

There has been an increase of community studies that incorporate the use of functional diversity indices. The incorporation of these indices in the analysis of marine communities is recent, however, could contribute with relevant information about the health of those communities. The lagoon of La Paz is a body of water located in La Paz, B.C.S., México. Despite its regional importance, there are not recent studies about its fish communities. Therefore, the aim of the present study was to analyze the temporal and spatial structure of the functional diversity of fish communities associated to soft bottoms, from August 2016 to July 2017, as well as important environmental variables. Functional diversity indices showed significant differences between months. Spatial analysis did not show significant differences perhaps due to low variability of the type of substrate. Temperature showed temporal differences as well. Therefore, temperature may be a limiting environmental variable for many fish species inhabiting coastal lagoons.

关键词： Coastal Lagoon Functional Diversity Functional Traits Fish Community