检索结果-南通市图书馆

World Journal of Transplantation 2024年第1期14卷 1-8页

作者： Cristian Lindner Raúl Riquelme Rodrigo San Martín Frank Quezada jorge valenzuela Juan P Maureira Martín Einersen Department of Radiology Faculty of MedicineUniversity of ConcepciónConcepción 4030000Chile Department of Radiology Hospital Clínico Regional Guillermo Grant BenaventeConcepción 4030000Chile Department of Statistics Catholic University of MauleTalca 3460000Chile Neurovascular Unit Department of RadiologyHospital Clínico Regional Guillermo Grant BenaventeConcepción 4030000Chile

Hepatic artery thrombosis(HAT)is a devastating vascular complication following liver transplantation,requiring prompt diagnosis and rapid revascularization treatment to prevent graft *** present,imaging modalities such as ultrasound,computed tomography,and magnetic resonance play crucial roles in diagnosing *** imaging techniques have improved sensitivity and specificity for HAT diagnosis,they have limitations that hinder the timely diagnosis of this *** this sense,the emergence of artificial intelligence(AI)presents a transformative opportunity to address these diagnostic *** development of machine learning algorithms and deep neural networks has demonstrated the potential to enhance the precision diagnosis of liver transplant complications,enabling quicker and more accurate detection of *** article examines the current landscape of imaging diagnostic techniques for HAT and explores the emerging role of AI in addressing future challenges in the diagnosis of HAT after liver transplant.

关键词： Liver transplantation Postoperative complications Hepatic artery Thrombosis Radiology Artificial intelligence

Variable-top stem biomass equations at tree-level generated by a simultaneous density-integral system for second growth forests of roble, raulí,and coigüe in Chile

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Forestry Research 2019年第3期30卷 993-1010页

作者： Carlos valenzuela Eduardo Acuna Alicia Ortega Geronimo Quinonez-Barraza Jose Corral-Rivas jorge Cancino Departamento Manejo de Bosques y Medio Ambiente Facultad de Ciencias ForestalesUniversidad de Concepcion Victoria 631Barrio Universitario4070386 ConcepcionChile Instituto de Bosques y Sociedad Facultad de Ciencias Forestales y Recursos NaturalesUniversidad Austral de ChileCampus Isla Teja5110566 ValdiviaChile Campo Experimental Valle del Guadiana Instituto Nacional de Investigaciones Forestales Agricolas y Pecuarias (INIFAP)km 4.5 Carretera Durango-Mezquital34170 DurangoDGOMexico Instituto de Silvicultura e Industria de la Madera Universidad de Juarez del Estado de Durango34120 DurangoMexico

Variable-top stem biomass models at the tree level for second growth forests of roble (Nothofagus obliqua), rauli(Nothofagus alpina), and coigüe (Nothofagus dombeyi) were fitted by a simultaneous density-integral system, which combines a stem taper model and a wood basic density model. For each model, an autoregressive structure of order 2 and a power equation of residual variance were incorporated to reduce residual autocorrelation and heteroscedasticity, respectively. By using dummy variables in the regression analysis, zonal effects on the parameters in the variable-top stem biomass equations were detected in roble. Consequently, equations for clusters of zones were obtained. These equations presented significant parameters and a high precision in both fitting and validation processes (i.e., CV<11.5% and CVp<11.9%, respectively), demonstrating that they are unbiased. The advantage of these types of functions is that they provide estimates of volume and biomass of sections of the stem, defined between any two points of the stem in the three species. Thus, depending on the final use of the wood and the dimensions of the tree, a stem fraction can be quantified in units of volume and the remaining fraction in units of weight.

关键词： Autocorrelation Density-integral Dummy variables Autoregressive error structure Heteroscedasticity

SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2020年第1期5卷 2322-2331页

作者： Xavier Palomer MSilvia Román-Azcona Javier Pizarro-Delgado Ana Planavila Francesc Villarroya Brenda valenzuela-Alcaraz Fátima Crispi Álvaro Sepúlveda-Martínez Irene Miguel-Escalada jorge Ferrer JFrancisco Nistal Raquel García Mercy MDavidson Emma Barroso Manuel Vázquez-Carrera Department of Pharmacology Toxicology and Therapeutic ChemistryIBUB(Institut de Biomedicina de la Universitat de Barcelona)Research Institute-Pediatric Research InstituteHospital Sant Joan de Déuand CIBER de Diabetes y Enfermedades Metabólicas Asociadas(CIBERDEM)Faculty of Pharmacy and Food SciencesUniversity of BarcelonaBarcelonaSpain Department of Biochemistry and Molecular Biomedicine IBUB and CIBER Fisiopatología de la Obesidad y Nutrición(CIBEROBN)Faculty of BiologyUniversity of BarcelonaBarcelonaSpain aBCNatal-Barcelona Center for Maternal–Fetal and Neonatal Medicine(Hospital Clínic and Hospital Sant Joan de Deu) Institut d’Investigacions Biomèdiques August Pi i SunyerUniversitat de Barcelonaand Center for Biomedical Research on Rare Diseases(CIBER-ER)BarcelonaSpain Genomic Programming of Betacells Laboratory Institut d’Investigacions August Pi i Sunyer(IDIBAPS)and CIBERDEMBarcelonaSpain Section of Epigenomics and Disease Department of Medicineand National Institute for Health Research(NIHR)Imperial Biomedical Research CentreImperial College LondonLondonUK Servicio de Cirugía Cardiovascular Hospital Universitario Marqués de ValdecillaDepartamento de Ciencias Médicas y QuirúrgicasFacultad de MedicinaUniversidad de CantabriaInstituto de Investigación Marqués de Valdecilla(IDIVAL)Centro de Investigación Biomédica en Red Cardiovascular(CIBERCV)Instituto de Salud Carlos IIISantanderSpain Departamento de Fisiología y Farmacología Facultad de MedicinaUniversidad de CantabriaInstituto de Investigación Marqués de Valdecilla(IDIVAL)SantanderSpain Department of Radiation Oncology Columbia UniversityNew YorkNYUSA

Sirtuin 3(SIRT3)is a deacetylase that modulates proteins that control metabolism and protects against oxidative *** of SIRT3 activity has been proposed as a promising therapeutic target for ameliorating metabolic diseases and associated cardiac *** this study,we investigated the role of SIRT3 in inflammation and fibrosis in the heart using male mice with constitutive and systemic deletion of SIRT3 and human cardiac AC16 ***3 knockout mice showed cardiac fibrosis and inflammation that was characterized by augmented transcriptional activity of *** with this,SIRT3 overexpression in human and neonatal rat cardiomyocytes partially prevented the inflammatory and profibrotic response induced by TNF-α.Notably,these effects were associated with a decrease in the mRNA and protein levels of FOS and the DNA-binding activity of ***,we demonstrated that SIRT3 inhibits FOS transcription through specific histone H3 lysine K27 deacetylation at its *** findings highlight an important function of SIRT3 in mediating the often intricate profibrotic and proinflammatory responses of cardiac cells through the modulation of the FOS/AP-1 *** fibrosis and inflammation are crucial in the progression of cardiac hypertrophy,heart failure,and diabetic cardiomyopathy,our results point to SIRT3 as a potential target for treating these diseases.

关键词： SIRT3 inflammation cardiac

Patterns of Genetic Diversity of the White-Nosed Coati Reveals Phylogeographically Structured Subpopulations in Mexico

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Natural Resources 2017年第1期8卷 31-53页

作者： Adrián Silva-Caballero Gloria León-ávila David valenzuela-Galván Jesús E. Maldonado jorge Ortega Laboratorio de Bioconservación y Manejo Posgrado en Ciencias Quimicobiológicas Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional Prolongación de Carpio y Plan de Ayala s/n Mexico City México Laboratorio de Genética Posgrado en Ciencias Quimicobiológicas Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional Prolongación de Carpio y Plan de Ayala s/n Mexico City México Centro de Investigación en Biodiversidad y Conservación (CIByC) Universidad Autónoma del Estado de Morelos Cuernavaca México Center for Conservation Genomics Smithsonian Conservation Biology Institute National Zoological Park Washington DC USA

Coatis (Procyonidae;Nasua) are considered the only truly social meso-carnivore mammals in Neotropical forests. In Mexico, white-nosed coatis (Nasua narica) are suspected to have undergone population reduction due to habitat loss and fragmentation and led to a lack of genetic adaptability and genetic isolation throughout its range. We examined patterns of genetic diversity and connectivity of five populations of Nasua narica distributed throughout Mexico (n = 60) by sequencing an ≈ 800 bp fragment of the mitochondrial cytochrome-b gene and also by screening 12 microsatellite loci. We found moderate to high levels of genetic variability for both genetic markers. We recorded twenty-two different cytochrome-b haplotypes throughout the 5 sampled areas and found that each of the sampled population of white-nosed coatis in Mexico harbors unique haplotypes and only three haplotypes were shared among two different populations that were closer geographically. All populations had high haplotype diversity (h) (0.968 ± 0.008 (SD)) but lower levels of nucleotide diversity (π) of 0.007 ± 0.001 (SD). All microsatellite loci were polymorphic in all of the populations and the mean number of alleles per locus was 5.033 ± 1.545 (SD) with expected (HE) and observed (HO) heterozygosity values of 0.774 and 0.664, respectively. However, low Wright F statistic values suggest the existence of a reduced heterozygosity (FST = 0.203, FIS = 0.134 and FIT = 0.310). Significant differences between the five populations confirmed isolation by distance, which suggests genetic structure among five subpopulations.

关键词： Alleles Cytochrome b Heterozygosity Microsatellites Nasua narica Procyonids

Diabetic Patients Develop Greater Intensity of Postoperative Pain than Non-Diabetics after Open Cholecystectomy: A Pilot Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biosciences and Medicines 2021年第6期9卷 67-75页

作者： Rocío Adriana Martínez-Alpuche Erick Mauricio Brindis-Fuentes Crystel Guadalupe Guzmán-Priego Francisco valenzuela-Priego Leonor Ivonne Parra-Flores jorge Elías Torres-López Pain Mechanisms Laboratory División Académica de Ciencias de la Salud Universidad Juárez Autónoma de Tabasco Villahermosa Tabasco México Department of Anaesthesiology Hospital Regional de Alta Especialidad “Dr. Juan Graham Casasús” Villahermosa Tabasco México

Background: Pre-clinical and clinical studies have shown that inflammatory pain intensity is increased under diabetes condition. Open cholecystectomy (OC) is a surgical procedure with predictable postoperative pain. However, the comparison of postoperative pain due to open cholecystectomy in diabetic and non-diabetic patients remains unknown. The research question to answer was whether diabetic patients undergoing OC development greater intensity of postoperative pain than non-diabetic patients. Methods: The study was conducted between June 2016 and February 2018 at the Regional Hospital of High Specialty “Dr. Juan Graham Casasús” of Villahermosa, Tabasco, Mexico. Seventy patients in two groups of 35 patients each scheduled for OC under general anesthesia were studied. Pain was assessed using the 11-point numerical rating scale (NRS). The primary endpoint was to know NRS pain scores after awaking of general anesthesia. Secondary outcomes included the time of onset of pain and comparing NRS scores between diabetic and non-diabetic patients undergoing OC. Results: Diabetic patients reported significantly greater intensity pain than non-diabetic patients. The mean overall pain score in the diabetic and non-diabetic patients was 7.2 ± 0.3 and 5.3 ± 0.3 (P = 0.0002), respectively. Furthermore, 60% of diabetic patients had severe pain (NRS ≥ 8) compared to 20% of non-diabetics (P = 0.006). The time to onset postoperative pain was about 35 minutes in both groups (P = 0.876). Conclusions: Diabetic patients undergoing OC have greater intensity postoperative pain and also more frequency of patients with severe pain scores compared with non-diabetic patients. Therefore, analgesic treatment in those patients should consider this point in order to provide a satisfactory postoperative analgesia.

关键词： Postoperative Pain Inflammatory Pain Cholecystectomy Diabetes Observational Study

智利南部拉姆萨尔湿地位点黑颈天鹅(Cygnus melancoryphus)的迁徙、死亡和大型植物水蕴草(Egeria densa)的灭绝

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

AMBIO－人类环境杂志 2007年第B11期36卷 572-574页

作者： Eduardo J.Lopetegui Roberto S.Vollmann Heraldo C.Cifuentes Cristian D.valenzuela Nelson L.Suarez Enrique P.Herbach jorge U.Huepe Gastón V.Jaramillo Bruno P.Leischner Ricardo S.Riveros 梁虹 Instituto de Zoologia Facultad de CienciasUniversidad Austral de Chile Departamento de Ciencias Básicas Universidad Santo Tomás Instituto de Patologia Animal Facultad de Ciencias VeterinariasUniversidad Austral de Chile Instituto de Histología Facultad de Medicina Universidad Austral de Chile

人类活动对全世界范围内生态系统服务和湿地功能的影响与日俱增。湿地生态系统具有重要的科学研究和社会价值，是生物多样性和水资源最丰富的地区。智利南部（大约39～41°s）目前，一些面积超过500hm^2的沿海和内地湿地受到临近城市工... 详细信息

人类活动对全世界范围内生态系统服务和湿地功能的影响与日俱增。湿地生态系统具有重要的科学研究和社会价值，是生物多样性和水资源最丰富的地区。智利南部（大约39～41°s）目前，一些面积超过500hm^2的沿海和内地湿地受到临近城市工业废弃物排放、未利用土地转变为耕地和水抽提的威胁。这些湿地大多位于瓦蒂文（Valdivian）雨林的沿海地区，该雨林具有独特的生物特性，植物多样性高，且由于广泛的土地利用变化而发生片段化。湿地和瓦蒂文雨林的这些特征促进了智利政府和国际社会对该生态系统的保护.

关键词：湿地功能植物多样性水资源智利生态系统服务土地利用变化天鹅迁徙