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Journal of Behavioral and Brain Science 2018年第10期8卷 519-537页

作者： jorge carlos hevia-orozco Araceli Sanz-Martin Instituto de Neurobiología Universidad Nacional Autónoma de México Querétaro México Instituto de Neurociencias Universidad de Guadalajara Guadalajara México

Children reared in institutional environments present emotional and cognitive affectations, as well as changes in the anatomy and functioning of certain cerebral areas, such as the prefrontal cortex. However, knowledge of the long run effect of these affectations remains scarce. Therefore, this study was designed to correlate the cortical electroencephalographic (EEG) and psychopathological parameters. Resting EEG from 10 institutionalized (IA) and 10 never-institutionalized adolescents (NIA) was obtained and this was parametrically correlated with the intensity of symptoms of depression, post-traumatic stress disorder (PTSD) and anxiety. Results showed that the IA group showed higher indices of depression, anxiety and PTSD, accompanied by low relative power (RP) in the fast bands, high activity in the slow bands in frontal areas, and higher alpha2 RP in temporal areas. In addition, IA showed higher EEG-correlations among frontal areas but lower EEG-correlations among prefrontal, parietal and temporal areas in the gamma band. We also found correlations between the EEG parameters and psychopathological scores. These EEG findings can contribute to improve our understanding of how stress experienced early in life may impact the development of the cortex, and how this, in turn, may predispose individuals to develop psychiatric conditions.

关键词： Adolescents Institutionalization EEG Activity Depression Anxiety

Prefrontal-Parietal Correlation during Performance of a Visuospatial Working Memory Task in Children, Adolescents and Young Adults

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Journal of Behavioral and Brain Science 2015年第10期5卷 448-457页

作者： Miguel Angel Guevara jorge carlos hevia-orozco Araceli Sanz-Martin Lucía Ester Rizo-Martínez Marisela Hernández-González Mayra Linné Almanza-Sepúlveda Instituto de Neurociencias CUCBA Universidad de Guadalajara Guadalajara México

Development of the prefrontal cortex and its connectivity with different cortical areas has strong implications for the improvement of working memory. The aim of this research was to characterize the interhemispheric (INTER) prefrontal and hemispheric (INTRA) frontopolar-dorsolateral prefrontal and dorsolateral prefrontal-parietal correlation (r) in children, adolescents and adults during performance of a visuospatial working memory task (VSWM). INTERr and INTRAr of 36 different aged male participants (11 - 13, 18 - 20 and 26 - 30 years old) were calculated during performance of the Corsi Block-Tapping task, which assessed VSWM. On this task, children showed lower correct responses than adolescents and adults. Adults also showed lower total execution times than children and adolescents, with a more efficient performance. On the EEGs, the older groups showed both higher interfrontal correlations and left and right prefronto-parietal correlations than children. According to our results, the progressive efficiency in VSWM is related to differences in EEG patterns among children, adolescents and adults.

关键词： Corsi Block-Tapping Task EEG Correlations Development Visuospatial Working Memory

Quick Review and Technical Approach for Regenerative Peripheral Nerve Interface Surgery

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Modern Plastic Surgery 2023年第4期13卷 126-131页

作者： Obed H Grajeda Chávez Andres Gallardo Castillo Samantha Colchado Mariscal Xunaxi Guadalupe Vázquez orozco Dulce Sánchez Dauth carlos Javier Mata Quintero jorge Montalvo Hernández Ricardo Palacios Merino Minerva Irene Hernandez Cristian Diaz Solleiro Department of Surgery Pemex Hospital Central Norte Mexico City Mexico

Regenerative peripheral nerve interface RPNI’s surgery was originally designed for prosthetic control. RPNI’s has demonstrated to be an effective tool to prevent neuroma formation by providing free muscle grafts as physiological targets for peripheral nerve ingrowth. Nerve transection injuries can result in painful neuromas that adversely affect patient recovery. This is especially significant following amputation surgeries, but they can also be used in surgeries in which the nerves can be visualized with a noticeable lesion. The first series of patients undergoing RPNI implantation for treatment of symptomatic postamputation neuromas was published in 2016. The series included a report of 46 patients undergoing RPNI. The clinical outcomes of RPNI have been optimistic with a reduction in neuroma pain up to 73% and phantom pain reduction of 53% along the uniformly high patient satisfaction. Since then, studies have been expanded, and knowledge regarding physiology has increased, providing us with new tools for a better understanding and giving these procedures more benefits and applications.

关键词： Component Formatting Style Styling Insert

Antioxidant drugs to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis:What does evidence suggest?

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World Journal of Gastroenterology 2015年第21期21卷 6745-6753页

作者： Clotilde Fuentes-orozco carlos Davalos-Cobian Jesus Garcia-Correa Gabriela Ambriz-Gonzalez Michel Dassaejv Macias-Amezcua Jesus Garcia-Renteria jorge Rendon-Felix Mariana Chavez-Tostado Lizbeth Araceli Cuesta-Marquez Andrea Socorro Alvarez-Villasenor Ana Olivia Cortes-Flores Alejandro Gonzalez-Ojeda Research Unit in Clinical Epidemiology Specialties Hospital of the Western Medical CenterMedical Unit of High SpecialtyMexican Institute of Social Security Guadalajara Jalisco 44340 Mexico Department Gastrointestinal Endoscopy Specialties Hospital of the Western Medical CenterMedical Unit of High SpecialtyMexican Institute of Social Security Guadalajara Jalisco 44340 Mexico Department of Pediatric Surgery.Children’s Hospital.Western National Medical Center Mexican Institute of Social Security Guadalajara Jalisco 44340 Mexico Health Research Coor-dination.Mexican Institute of Social Security Baja Californa Sur 23000 Mexico

AIM:To determine whether or not the use of antioxidant supplementation aids in the prevention of post-endoscopic retrograde cholangiopancreatography ***:A systematic review of randomized controlled trials(RCTs) was made to evaluate the preventive effect of prophylactic antioxidant supplementation in post-endoscopic retrograde cholangiopancreatography pancreatitis(PEP).The inclusion criteria included:acute post-endoscopic retrograde cholangiopancreatography pancreatitis in adults; randomized clinical trials with the use of any antioxidant as an intervention compared with placebo,to reduce *** outcome measure was the incidence and severity of *** RCTs involving 3110 patients since 1999 *** antioxidants used were selenite,β-carotene,and pentoxifylline(each one in one trial),N-acetylcysteine(NAC) in three trials,and allopurinol in six *** group of patients treated with NAC received different doses; either oral or intravenous,and allopurinol-treated patients received five different oral doses in two different administration *** results are expressed with raw numbers,proportions,as well as mean and standard *** incidence of pancreatitis between groups was analyzed with Pearson's χ2 test or Fisher's exact test(F).The main outcome is expressed as relative risks and 95%***:The incidence of pancreatitis in all antioxidant treatment groups was 8.6%,whereas it was 9.7% in the control *** antioxidants used were selenite,β-carotene,and pentoxifylline(each one in one trial),NAC in three trials,and allopurinol in six *** allopurinol trials,three different dosifications were used; two trials reported a low dosage(of less than 400 mg),two trials reported a moderate dose(600 mg) and the remaining two employed higher doses(more than 900 mg).Supplementation was not associated with a significant reduction in the incidence of PEP [relative risk(RR) = 0.93; 95%CI:0.82-1.06; P = 0.28].In addition,the incid

关键词： Antioxidant drugs Endoscopic retrograde cholangiopancreatography Pancreatitis Prophylaxis

Quick Review and Technical Approach for Regenerative Peripheral Nerve Interface Surgery

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