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Immediate effects of Tuina techniques on working-related musculoskeletal disorder of professional orchestra musicians

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Journal of Integrative Medicine 2015年第4期13卷 257-261页

作者： Cláudia Maria Sousa luis Moreira Daniela Coimbra jorge Machado Henry J.Greten University of Porto Institute of Biomedical Sciences Abel Salazar Jean Piaget Health Superior School Research in Education and Community Intervention–RECI Porto Polytechnic Institute Superior School of Music and Performing Arts German Society of Traditional Chinese Medicine Heidelberg School of Chinese Medicine

BACKGROUND：Musicians are a prone group to suffer from working-related musculoskeletal disorder（WRMD）.Conventional solutions to control musculoskeletal pain include pharmacological treatment and rehabilitation programs but their effi ciency is sometimes ***：The aim of this research is to study the immediate effects of Tuina techniques on WRMD of professional orchestra musicians from the north of ***,SETTING,PARTICIPANTS AND INTERVENTIONS：We performed a prospective,controlled,single-blinded,randomized *** orchestra musicians with a diagnosis of WRMD were randomly distributed into the experimental group（n=39）and the control group（n=30）.During an individual interview,Chinese diagnosis took place and treatment points were *** acupoints were treated by Tuina techniques into the experimental group and non-specifi c skin points were treated into the control *** was measured by verbal numerical scale before and immediately after ***：After one treatment session,pain was reduced in 91.8%of the cases for the experimental group and 7.9%for the control ***：Although results showed that Tuina techniques are effectively reducing WRMD in professional orchestra musicians of the north of Portugal,further investigations with stronger measurements,double-blinding designs and bigger simple sizes are needed.

关键词： diagnosis(TCM) stress Tuina musicians musculoskeletal disorders

Transmission of cryptococcosis by liver transplantation:A case report and review of literature

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World Journal of Hepatology 2020年第5期12卷 253-261页

作者： Gustavo de Sousa Arantes Ferreira Andre luis Conde Watanabe Natalia de Carvalho Trevizoli Fernando Marcus Felippe jorge Carolina de Fatima Couto Priscila Brizolla de Campos Gabriel Oliveira Nunes Caja Department of Liver Transplantation Instituto de Cardiologia do Distrito FederalBrasilia 70673900Brazil

BACKGROUND Cryptococcosis is a fungal infection caused by the yeast-like encapsulated basidiomycetous fungus of the Cryptococcus neoformans(***)species *** fungi are ubiquitous in soil and bird droppings,and infection by them is an important global health concern,particularly in immunosuppressed patients,such as organ transplant recipients and those infected by the human immunodeficiency *** fungus usually enters the body through the respiratory tract,but extremely rare cases of infection acquired by transplantation of solid organs have been *** SUMMARY We report a case of disseminated cryptococcosis in a liver transplant recipient,diagnosed 2 wk after the *** patient initially presented with fever,hyponatremia and elevated transaminase levels,manifesting intense headache after a few *** cultures were positive for *** biopsy showed numerous fungal elements surrounded by gelatinous matrix and sparse granulomatous *** resonance imaging of the brain showed multiple small lesions with low signal in T2,peripheric enhancement and edematous halo,diffuse through the parenchyma but more concentrated in the subcortical *** with amphotericin B for 3 wk,followed by maintenance therapy with fluconazole,led to complete resolution of the *** recipients of both kidneys from the same donor also developed disseminated cryptococcosis,confirming the transplant as the source of *** organ donor lived in a rural area,surrounded by tropical rainforest,and had negative blood cultures prior to organ *** This case highlights the risk of transmission of fungal diseases,specifically of ***,through liver graft during liver transplantation.

关键词： Cryptococcosis Liver transplantation Cryptococcus neoformans Case report Immunosuppression Fungal infection

IL-1β, TNF-α and Sambucus nigra Reactive Serum Proteins as Biomarkers of Mild Cognitive Impairment and Alzheimer Disease Progression

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Advances in Alzheimer's Disease 2015年第4期4卷 99-109页

作者： luis Manuel Castillo Enrique Moreno Yaneth Rodriguez-Agudelo MireyaChavez-Oliveros Zoila Trujillo Blanca Espinosa Emma Rodriguez-Maldonado luis Felipe Montano jorge Guevara Departamento de Bioquimica Facultad de MedicinaUniversidad Nacional Autonoma de MexicoMexico CityMexico Departamento de Neuropsicologia Instituto Nacional de Neurologia y NeurocirugiaMexico CityMexico Geriatra Instituto Nacional de Neurologia y Neurocirugia Mexico CityMexico Laboratorio de Bioquimica Instituto Nacional de Enfermedades RespiratoriasMexico CityMexico Departamento de Fisiología Instituto Nacional de CardiologiaMexico CityMexico Departamento de Biologia Celular y Tisular Facultad de MedicinaUniversidad Nacional Autonoma de MexicoMexico CityMexico

Amyloid-β (Aβ) can induce a chronic inflammatory immune response that is associated, amongst many others, to abnormal glycosylation, inducible nitric oxide synthase (iNOS) and nitric oxide (NO). The relation between development of Mild Cognitive Impairment (MCI) and Alzheimer’s disease progression and these serum markers has not been evaluated. Serum levels of iNOs, NO, TNF-α, IL-1β, IL-6, IL-8, IL-10, and IL-12 are determined with commercially available kits. Sialylation of albumin-free serum patterns is determined by Western blot analysis with Sambucus nigra (specific for sialic acid attached to terminal galactose in α2,6 linkage) lectin. Apolipoprotein E (ApoE) haplotype is determined by Western blot using specific anti-ApoE 2, 3 or 4 antibodies. A mini-mental state examination (MMSE) test is also performed in the 10 MCI patients, 19 Alzheimer’s disease (AD) patients and 46 healthy age-matched controls evaluated. The results show an increase of iNOS in MCI and AD but significantly higher NO concentrations are only found in MCI patients. TNF-α and IL-1β concentrations are the only significantly increased cytokines in MCI patients;no differences between control and MCI or AD patients are found in regard to the other cytokines. An abnormal MMSE test result only correlates with a decrease in serum NO concentration in MCI patients. The terminal sialic acid linkage pattern of serum proteins also shows highly significant differences between MCI and AD patient. ApoE3/4 or 4/4 haplotypes are characteristic of MCI and AD patients. Our results imply that increased serum TNF-α, IL-1β, iNOS, NO and alterations of serum proteins glycosylation patterns in adult individuals with an abnormal MMSE test may serve as an early biomarker of MCI and AD development.

关键词： Alzheimer Disease Mild Cognitive Impairment Nitric Oxide Inflammatory Cytokines Glycosylation Apolipoprotein E4

火地岛森林管理:是对环境的又一个威胁还是可持续发展的一个机会?

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产业与环境 2000年第2期22卷 75-78页

作者： jorge luis Frangi Director LISEA(Laboratorio de Investigación de Sistemas Ecológicos y Ambientales)Universidad Nacional de La PlataDiagonal 113 Nro 4691900 La PlataArgentina

为这片世界最南端的森林提出的一个主要森林管理和家具木材生产方案的可能影响 ,已经引起广泛关注 .对这些原始森林的未来所给予的注意 ,突出说明了环境保护 /生物多样性保护与经济效益之间的冲突 .火地岛的公共当局和居民处在一个能指... 详细信息

为这片世界最南端的森林提出的一个主要森林管理和家具木材生产方案的可能影响 ,已经引起广泛关注 .对这些原始森林的未来所给予的注意 ,突出说明了环境保护 /生物多样性保护与经济效益之间的冲突 .火地岛的公共当局和居民处在一个能指定他们合意的生活方式与环境质量的地位 ,而且能参与旨在以适合于其社会、经济和生态的条件和期望的方式确保可持续性的决策 .

关键词：火地岛森林管理环境可持续发展南美洲

Corticosteroids for severe influenza pneumonia: A critical appraisal

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World Journal of Critical Care Medicine 2016年第1期5卷 89-95页

作者： Wagner luis Nedel David garcia Nora jorge Ibrain Figueira Salluh Thiago Lisboa Pedro Póvoa Intensive Care Unit Hospital Nossa Senhora da Concei??o Intensive Care Unit Vila Franca de Xira Hospital D’or Institute for Research and Education Critical Care Department Hospital de Clinicas de Porto Alegre Post-Graduation Program (PPG) Pneumology Universidade Federal do Rio Grande do Sul Polyvalent Intensive Care Unit S?o Francisco Xavier Hospital Centro Hospitalar de Lisboa Ocidental Nova Medical School CEDOC New University of Lisbon

Influenza pneumonia is associated with high number of severe cases requiring hospital and intensive care unit(ICU) admissions with high mortality. Systemic steroids are proposed as a valid therapeutic option even though its effects are still controversial. Heterogeneity of published data regarding study design, population demographics, severity of illness, dosing, type and timing of corticosteroids administered constitute an important limitation for drawing robust conclusions. However, it is reasonable to admit that, as it was not found any advantage of corticosteroid therapy in so diverse conditions, such beneficial effects do not exist at all. Its administration is likely to increase overall mortality and such trend is consistent regardless of the quality as well as the sample size of studies. Moreover it was shown that corticosteroids might be associated with higher incidence of hospital-acquired pneumonia and longer duration of mechanical ventilation and ICU stay. Finally, it is reasonable to conclude that corticosteroids failed to demonstrate any beneficial effects in the treatment of patients with severe influenza infection. Thus its current use in s evere influenza pneumonia should be restricted to very selected cases and in the setting of clinical trials.

关键词： Influenza Mechanical ventilation Pneumonia Corticosteroids Respiratory failure

Intermittent chaos for ergodic light trapping in a photonic fiber plate

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Light(Science & Applications) 2016年第1期5卷 209-215页

作者： Marina Mariano Gregory Kozyreff luis G Gerling Pablo Romero-Gomez Joaquim Puigdollers jorge Bravo-Abad Jordi Martorell ICFO-Institut de Ciencies Fotoniques The Barcelona Institute of Science and TechnologyCastelldefels(Barcelona)08860Spain Département de Physique UniversitéLibre de Bruxelles(ULB)Campus de la PlaineBruxelles B-1050Belgium Departament Enginyeria Electrònica Universitat Politècnica de CatalunyaBarcelona 08034Spain Departamento de Física Teórica de la Materia Condensada and Condensed Matter Physics Center(IFIMAC) Universidad Autónoma de MadridMadrid 28049Spain Departament de Física Universitat Politècnica de CatalunyaTerrassa 08222Spain

Extracting the light trapped in a waveguide,or the opposite effect of trapping light in a thin region and guiding it perpendicular to its incident propagation direction,is essential for optimal energetic performance in illumination,display or light harvesting *** we demonstrate that the paradoxical goal of letting as much light in or out while maintaining the wave effectively trapped can be achieved with a periodic array of interpenetrated fibers forming a photonic fiber *** entering perpendicular to that plate may be trapped in an intermittent chaotic trajectory,leading to an optically ergodic *** fabricated such a photonic fiber plate and showed that for a solar cell incorporated on one of the plate surfaces,light absorption is greatly *** this,we found the unexpected result that a more chaotic photon trajectory reduces the production of photon scattering entropy.

关键词： chaos ergodicity fiber light-guiding plate light harvesting light trapping

PET/CT with <sup>18</sup>F-PSMA in Patients with Prostate Cancer, Review of the Initial Experience

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Open Journal of Urology 2021年第4期11卷 158-175页

作者： Jhonatan Gómez Domínguez jorge Martin Schalch Ponce de León Jose luis Criales Cortés Department of PET/CT in CT Scanner San Angel Mexico City Mexico

METHOD: We carry out an observational study where reviewed the PET/CT studies with PSMA marked with Fluor-18 (18F) carried out from February 2019 to September 2020. We analyzed the average value of hepatic uptake SUV lean average (SUVlave), acquisition time, age, reason from the study, focal, multifocal and diffuse prostate uptake, analysis of the location of metastases, level of prostate specific antigen (PSA), we describe uptakes of non-prostate origin and focal uptakes in ribs without anatomical representation. RESULTS: The average hepatic SUVlave was 9.7, the acquisition times were variable (52 - 183 minutes) without alterations in the white-background relationship, the most frequent indication for the study was staging, the uptake in ribs without anatomical representation were considered benign with certain characteristics, PET/CT has the ability to detect neoplastic activity with low PSA levels in lymph nodes CONCLUSION: PET/CT with 18F-PSMA has advantages over bone scan and computed tomography of the abdomen and pelvis for the staging of prostate cancer.

关键词： 18F-PSMA Prostate Cancer Non-Prostatic Uptakes

Evaluating Oblique Shock Waves Characteristics on a Double-Wedge Airfoil

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Engineering（科研） 2016年第12期8卷 862-871页

作者： jorge luis Garrido Tellez Eusebio Hernandez-Martinez Miguel Toledo Velazquez Jose Angel Ortega Herrera Pedro Quinto-Diez Instituto Politecnico Nacional SEPI ESIME Ticoman Ciudad de Mexico Mexico Instituto Politecnico Nacional SEPI ESIME Zacatenco Ciudad de Mexico Mexico

Numerical and experimental study to evaluate aerodynamic characteristics in supersonic ow over a double wedge airfoil is carried out using Fluent software and a supersonic wind tunnel, respectively. The Schlieren visualization method was also used to develop the experimental step of this study. The supersonic wind tunnel reached a proximately a Mach number of 1.8. The result got showed oblique shock waves visualization on double-wedge airfoil and the numerical simulation, the flow behavior as function of Mach number, pressure, temperature and density in the flow field on the computational model. The simulation allowed to observe the shock wave and the expansion fan in the leading and tailing edge of double-wedge airfoil. From the numerical and experimental comparison, an agreement at the shock wave angle and Mach number was observed, with a difference about 1.17% from the experimental results.

关键词： Oblique Shock Waves Supersonic Airfoil Flow Visualization Numerical Simulation Schlieren Method

Design optimization of multilayer perceptron neural network by ant colony optimization applied to engine emissions data

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Science China(Technological Sciences) 2019年第6期62卷 1055-1064页

作者： MARTINEZ-MORALES Jose QUEJ-COSGAYA Hector LAGUNAS-JIMENEZ Jose PALACIOS-HERNANDEZ Elvia MORALES-SALDANA jorge Faculty of Engineering Autonomous University of Campeche Campeche 24039 Mexico Faculty of Sciences Autonomous University of San Luis Potosi San Luis Potosi 78290 Mexico Faculty of Engineering Autonomous University of San Luis Potosi San Luis Potosi 78290 Mexico

A multilayer perceptron(MLP) artificial neural network(ANN) model has been optimized by the multi-objective ant colony optimization(MOACO) algorithm, which uses three objective functions. A sensitivity analysis to choose MOACO parameter values is carried out by calculating hypervolume metric, and the proposed approach adopts the Vlsekriterijumska Optimizacija I Kompromisno Resenje(VIKOR) decision method to choose final compromised solution on the Pareto front obtained from MOACO. As a result, we used the MLP-MOACO developed model to estimate the value of engine emissions of NOxin a four stroke, spark ignition(SI) gasoline engine and observed acceptable correlation coefficient(R^2) of 0.99978.

关键词： ant colony optimization multilayer perceptron artificial neural networks hypervolume engine emissions