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Epidemiology of work-related hand and wrist injuries in a referral center: A descriptive study

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World Journal of Orthopedics 2024年第7期15卷 650-659页

作者： Angélica M Rodríguez Ginna P Tocanchón Jessica T Villalba Luis M Pombo Aníbal A Teherán gabriel Camero-ramos Karen P Ayala Gerhard M Acero Research Center Fundación Universitaria Juan N.CorpasBogotá111321Colombia Red Cross Cruz Roja Colombiana-Seccional Cundinamarca BogotáBogotá111221Colombia Vigilancia Epidemiológica Instituto Nacional de SaludBogotá111321Colombia

BACKGROUND Occupational hand and wrist injuries(OHWIs)account for 25%of work-related accidents in low-and middle-income *** Colombia,more than 500000 occupational accidents occurred in 2021,and although the rate declined to less than 5%in 2020 and 2021,at least one in four accidents involved a hand or wrist *** To describe the OHWIs in workers seen at the emergency room at a second-level hospital in *** An observational study was performed using data from workers who experienced OHWIs and attended a second-level hospital,between June,2020 and May,*** overall frequency of OHWIs,as well as their distribution by sociodemo-graphic,clinical,and occupational variables,are ***,association patterns between sex,anatomical area(fingers,hand,wrist),and type of job were analyzed by correspondence analysis(CA).RESULTS There were 2.101 workers treated for occupational accidents,423(20.3%)were cases of OHWIs,which mainly affected men(93.9%)with a median age of 31 years and who worked mainly in mining(75.9%).OHWIs were more common in the right upper extremity(55.3%)and comprised different types of injuries,such as contusion(42.1%),laceration(27.9%),fracture(18.7%),and crush injury(15.6%).They primarily affected the phalanges(95.2%),especially those of the first finger(25.7%).The CAs showed associations between the injured anatomical area and the worker’s job that differed in men and women(explained variance>90%).CONCLUSION One out of five workers who suffered occupational accidents in Cundinamarca,Columbia had an OHWI,affecting mainly males employed in *** occupational profile is likely to lead to prolonged rehabilitation,and permanent functional *** results might be useful for adjusting preventive measures in cluster risk groups.

关键词： Accidents Occupational Epidemiology Hand injuries Wrist injuries Occupational health

Enhancement of the Antigenotoxic and Antioxidant Actions of Eugenol from Spice Clove and the Stabilizer Gum Arabic on Colorectal Carcinogenesis

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Food and Nutrition Sciences 2024年第1期15卷 71-100页

作者： Nayanna de Oliveira ramos Melo Lucas gabriel da Costa Marques Humberto Maia Costa Neto Matheus De Sousa Silva Francisco Vagnaldo Fechine Jamacaru Bruno Coêlho Cavalcanti Antônio Adailson De Sousa Silva Conceição Aparecida Dornelas Postgraduate Program in Medical-Surgical Sciences School of Medicine Federal University of Ceará Fortaleza Brazil School of Medicine Federal University of Ceará Fortaleza Brazil Nucleus of Research and Development of Medicines (NPDM) Laboratory of Pharmacology and Preclinical Research School of Medicine Federal University of Ceará Fortaleza Brazil Nucleus for Research and Development of Medicines (NPDM) National Laboratory of Experimental Oncology Federal University of Ceará Fortaleza Brazil Postgraduate Program in Pathology and Medical-Surgical Sciences School of Medicine Federal University of Ceará Fortaleza Brazil

Spices are defined as any aromatic condiment of plant origin used to alter the flavor and aroma of foods. Besides flavor and aroma, many spices have antioxidant activity, mainly related to the presence in cloves of phenolic compounds, such as flavonoids, terpenoids and eugenol. In turn, the most common uses of gum arabic are in the form of powder for addition to soft drink syrups, cuisine and baked goods, specifically to stabilize the texture of products, increase the viscosity of liquids and promote the leavening of baked products (e.g., cakes). Both eugenol, extracted from cloves, and gum arabic, extracted from the hardened sap of two species of the Acacia tree, are dietary constituents routinely consumed virtually throughout the world. Both of them are also widely used medicinally to inhibit oxidative stress and genotoxicity. The prevention arm of the study included groups: Ia, IIa, IIIa, Iva, V, VI, VII, VIII. Once a week for 20 weeks, the controls received saline s.c. while the experimental groups received DMH at 20 mg/kg s.c. During the same period and for an additional 9 weeks, the animals received either water, 10% GA, EUG, or 10% GA + EUG by gavage. The treatment arm of the study included groups Ib, IIb, IIIb e IVb, IX, X, XI, XII). Once a week for 20 weeks, the controls received saline s.c. while the experimental groups received DMH at 20 mg/kg s.c. During the subsequent 9 weeks, the animals received either water, 10% GA, EUG or 10% GA + EUG by gavage. The novelty of this study is the investigation of their use alone and together for the prevention and treatment of experimental colorectal carcinogenesis induced by dimethylhydrazine. Our results show that the combined use of 10% gum arabic and eugenol was effective, with antioxidant action in the colon, as well as reducing oxidative stress in all colon segments and preventing and treating genotoxicity in all colon segments. Furthermore, their joint administration reduced the number of aberrant crypts and th

关键词： Eugenol Gum Arabic Carcinogenesis Oxidative Stress Genotoxicity

Enhancement of the Antigenotoxic and Antioxidant Actions of Eugenol from Spice Clove and the Stabilizer Gum Arabic on Colorectal Carcinogenesis

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Numerical Study of Highly Nonlinear Photonic Crystal Fiber with Tunable Zero Dispersion Wavelengths

Food and Nutrition Sciences（食品与营养科学） 2024年第1期

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Journal of Electromagnetic Analysis and Applications 2015年第5期7卷 141-151页

作者： Alejandro Barrientos García Igor A. Sukhoivanov José Amparo Andrade Lucio Oscar Gerardo Ibarra Manzano Igor Guryev Juan Carlos Hernández García gabriel ramos Ortiz Department of Electronics Engineering Universidad de Guanajuato Salamanca Mexico Department of Multidisciplinary Studies Universidad de Guanajuato Yuriria Mexico CONACYT Cátedras CONACYT Ciudad de Mexico Mexico Centro de Investigaciones en óptica A. C. GPOM León Mexico

Solid-core silica photonic crystal fiber is proposed borrowing the concept of golden ratio (1.618) and keeping it between pitch and air hole diameter Λ/d in a subset of six rings of air-holes with hexagonal arrangement. In the case when we have a pitch equal to one micron (Λ = 1 μm), we need air-holes diameters d = 0.618 μm in order to achieve two zero dispersion wavelength (ZDW) points at 725 nm and 1055 nm;this gives us the possibility to use the fiber for supercontinuum generation, by pumping close to that points, pulse compression or reshaping. We analyzed a series of fibers using this relation and showed the possibilities of tunable ZDW in a wide range of wavelengths from 725 nm to 2000 nm, with low losses and small effective area. In agreement with the ZDW point needed, the geometry of the structure can be modified to the point of having only three rings of air holes that surround the solid core with low losses and good confinement mode. The design proposed here is analyzed using the finite element method with perfectly matched layers, including the material dispersion directly into the model applying the Sellmeier’s equation.

关键词： Photonic Crystal Fibers Supercontinuum Generation Zero Dispersion Wavelength

Antioxidant Action of Rosemary and Oregano Extract in Pre-Cooked Meat Hamburger

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Food and Nutrition Sciences 2018年第7期9卷 806-817页

作者： Maria Raquel Manhani Maria Aparecida Nicoletti Andrea Carla Da Silva Barretto Graciele Riveres De Jesus Camila Munhoz gabriel ramos De Abreu Julia Zaccarelli-Magalhaes Andre Rinaldi Fukushima Instituto Federal de Sã o Paulo(IFSP) Campus SuzanoSuzanoBrazil Faculty of Pharmaceutical Sciences University of Sao PauloSao PauloBrazil Instituto de Biociencias Letras e Ciências Exatas de Sao Jose do Rio Preto Universidade Estadual Paulista Júlio de Mesquita FilhoSao Josédo Rio PretoBrazil Universidade Sao Judas Tadeu Sao PauloBrasil Department of Pathology School of Veterinary Medicine and Animal ScienceUniversity of Sao PauloSao PauloBrazil Health Science Institute Presbiterian Mackenzie UniversitySao PauloBrazil

The main goal is to compare the antioxidant potential of rosemary and oregano natural extracts in precooked beef burger by assessing the lipid oxidation extent and sensory analysis. Five formulations (F) of hamburger were prepared from beef and mechanically separated as follows: meat containing sodium erythorbate (F1);deodorized rosemary extract (F2);oregano extract (F3);rosemary plus oregano extracts (F4) and without antioxidant addition, denominated control formulation (CF). The samples were frozen at ?18°C for 24 hours, then submitted to heat treatment in an electric oven with internal controlled temperature of 75°C, and again frozen for a period of 30 days. The lipid oxidation extent (determined by thiobarbituric acid reactive substances— TBRS) was evaluated at 0, 15 during 30 days. After heating in plate to temperature of 75°C, the samples were submitted to color, taste and odor evaluation by 40 untrained tasters. The formulations F1, F2 and F4 presented lower concentrations of TBRS, whereas CF at day zero already showed very high values, indicating oxidation of the product. The samples showed good acceptance in the sensorial analysis.

关键词： Rosemary Extract Oregano Extract Food Composition Food Preservation Food Quality Meat Product

Nutrimental diagnosis of avocado(Persea americana Mill.)“Haas”,soil fertility and water quality in Cuernavaca,Morelos,Mexico

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Agricultural Sciences 2013年第9期4卷 491-498页

作者： Hector Sotelo-Nava Oscar gabriel Villegas-Torres Martha Lilia Domínguez-Patino Francisco Perdomo-Roldán Elías Hernández Castro Agustín Damián Nava Margarita ramos García Facultad de Ciencias Agropecuarias Universidad Autónoma del Estado de MorelosCuernavacaMexico Facultad de Ciencias Químicas e Ingeniería Universidad Autónoma del Estado de MorelosCuernavacaMexico Unidad Academica de Ciencias Agropecuarias y Ambientales Universidad Autónoma de GuerreroIgualaMexico

In two contrasting agricultural ecohabitats (agrohabitats) in the avocado production area in the municipality of Cuernavaca, Morelos, an analysis of nutrimental status, soil fertility and water quality was conducted to measure soil fertility levels and to determine the nutrimental state of the trees. The “Hass” variety avocado groves studied had an average age of 8 years;the first grove was planted in an acrisol soil (1700 to 1900 meters above mean sea level [mamsl]);the second, in an andosol soil (1200 to 1700 mamsl). In each agrohabitat, tests were performed to determine the soil’s physical and chemical characteristics. The physical and chemical characteristics of the soils of this zone differ as do the nutrimental states of the avocado trees in the two agrohabitats. The trees showed excessive concentration of Ca, Fe, S, Z and Mg. The indices of Deviation from Optimal Percentage (DOP) in the two agrohabitats showed different nutrimental requirements;nevertheless, they were low and very near to zero, 14.218 and 13.350 respectively. The water used for the agricultural irrigation was low in salinity and sodium content and thus may be used for the agricultural irrigation without restrictions.

关键词： Avocado Nutrimental Imbalance Index Diagnosis Nutrimental Status Nutrients

Rat Hepatocyte Glucose Metabolism Is Affected by Caloric Restriction but not by Litter Size Reduction

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Journal of Pharmacy and Pharmacology 2017年第7期5卷 408-415页

作者： Nayra Thais Delatorre Branquinho gabriel Henrique de Paula Cruz Arielle da Cunha Silvéio Leticia Diniz repaldi Lais Akemi Yamada Isabela ramos Mariano Vilma Aparecida Ferreira de Godoi Maria ontserrat Diaz Pedrosa Program of Graduate Studies in Biological Sciences State University of Maringá Maringá 87020-900 Brazil Undergraduation in Biological Sciences State University of Maringá Maringá 87020-900 Brazil Undergraduation in Biotechnology State University of Maringá Maringá 87020-900 Brazil Department of Physiological Sciences State University of Maringá Matingá 87020-900 Brazil

This work aimed at investigating whether the liver glucose metabolism could have a role in any change of glucose homeostasis that might exist in the reduced-litter rat at the age of 60 days. Additionally, post-weaning caloric restriction and its hepatic effects were explored, as this intervention is reported as a useful measure against obesity and its related disturbances. The animals were raised in litters of nine （control, CG） or three pups during lactation. These small-litter pups were FG （fed freely） or subjected to 30% RG （caloric restriction） after weaning until 60 days of age. The increased adiposity induced by lactational overfeeding was not reversed by caloric restriction. Hepatocyte glucose metabolism and glucose tolerance test were not affected by litter size, but caloric restriction increased liver basal glucose release, diminished gluconeogenesis and retarded the glycemic decay during the insulin tolerance test. Liver glucose metabolism of young adult rats was not affected by lactational overfeeding. Up to this age, however, moderate caloric restriction had a potent influence that might compromise whole-body glucose homeostasis and prompt to insulin resistance.

关键词： Small litter caloric restriction glucose metabolism rat liver.

Determination of Paraquat in Several Commercially Available Types of Rice

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Food and Nutrition Sciences 2018年第12期9卷 1368-1375页

作者： Thais Lopes Lima Maria Aparecida Nicoletti Camila Munhoz gabriel ramos De Abreu Julia Zaccarelli Magalhaes Esther Lopes Ricci Ricci Paula A.Faria Waziry Júlia Nathalia Alves da Costa Ana Carolina Nascimento Antonio AndréRinaldi Fukushima Universidade Sao Judas Tadeu-R.Taquari Sao Paulo/SPBrazil Departamento de Farmacia.Faculdade de Ciencias Farmaceuticas.Universidade de Sao Paulo Sao Paulo/SPBrazil Instituto de Ciencias da Saude Universidade Presbiteriana MackenzieRua da ConsolacaoSao Paulo/SPBrazil Departamento de Patologia Faculdade de Medicina Veterinaria e ZootecniaUniversidade de Sao PauloSao Paulo/SPBrazil New Southeastern University Fort LauderdaleFloridaUnited States of America Veterans Affairs Medical CenterMiamiFloridaUSA Faculdade Sao Bento-Largo de Sao Bento s/no-CentroSao Paulo-SPSao Paulo/SPBrazil

Introduction: Paraquat (1,1’-dimethyl-4,4’-bipyridine-dichloride) is a herbicide used to combat weeds and improve crop productivity. Its acute toxicity can cause fatal poisoning in humans and animals and several studies have shown a strong correlation between paraquat and Parkinson’s disease. Objective: To determine the concentration of paraquat in different types of rice in Brazil. Method: Paraquat quantification is based on a complexation reaction with sodium dithionite, which generates a blueish color compound, whose absorbance was read in a spectrophotometer at the 600 nm wavelength. Results: Five samples were found to be above the maximum allowed limit, while one sample had a concentration in the upper allowed limit. The method employed did not allow quantification of black rice. Conclusion: There is a need for identification of the type of pesticide used in each examined crop as well as their respective dates of remission in order to improve the safety of agricultural practices.

关键词： Paraquat Herbicide Rice

Diagnosis and management of small bowel neuroendocrine tumors:A state-of-the-art

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World Journal of Methodology 2022年第5期12卷 381-391页

作者： Jhean gabriel Gonzáles-Yovera Pela J Roseboom Marcio Concepción-Zavaleta Isamar Gutiérrez-Córdova Esteban Plasencia-Dueñas María Quispe-Flores Anthony ramos-Yataco Carlos Alcalde-Loyola Frederick Massucco-Revoredo JoséPaz-Ibarra Luis Concepción-Urteaga Division of Gastroenterology María Auxiliadora HospitalLima 15801Peru Division of Emergency Medicine Regional Academic Hospital of TrujilloTrujillo 13011Peru Division of Endocrinology Stella Maris ClinicLima 15084Peru Division of Gastroenterology Guillermo Almenara Irigoyen National HospitalLima 12590Peru Division of Endocrinology Guillermo Almenara Irigoyen National HospitalLima 12590Peru Division of Internal Medicine Ricardo Cruzado Rivarola HospitalIca 110301Peru School of Medicine National University of TrujilloTrujillo 13007Peru Department of Medicine School of MedicineNational University of San MarcosLima 15001Peru Division of Internal Medicine School of MedicineNational University of TrujilloTrujillo 13011Peru

This review provides an update on the epidemiology,pathophysiology,symptoms,diagnosis and treatment of neuroendocrine neoplasms(NENs)of the small bowel(SB).These NENs are defined as a group of neoplasms deriving from neuroendocrine *** are currently the most common primary tumors of the SB,mainly involving the ileum,making the SB the most frequently affected part of the gastrointestinal *** NENs by definition are located between the ligament of Treitz and the ileocecal *** are characterized by small size and induce an extensive fibrotic reaction in the small intestine including the mesentery,resulting in narrowing or twisting of the *** manifestations of bowel functionality are related to the precise location of the primary *** majority of them are non-functional NENs and generally asymptomatic;in an advanced stage,NENs present symptoms of mass effect by non-specific abdominal pain or carcinoid syndrome which appears in patients with liver metastasis(around 10%).The main manifestations of the carcinoid syndrome are facial flushing(94%),diarrhea(78%),abdominal cramps(50%),heart valve disease(50%),telangiectasia(25%),wheezing(15%)and edema(19%).Diagnosis is made by imaging or biochemical tests,and the order of request will depend on the initial diagnostic hypothesis,while confirmation will always be *** patients with a localized SB NEN with or without near metastasis in the mesentery are recommended for curative *** and distant spread may be susceptible to several therapeutic strategies,such as chemotherapy,somatostatin analogs and palliative resection.

关键词： Neuroendocrine Tumor Small bowel Small intestine Gastrointestinal disease Treatment Survival