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On the material dependency of peri-implant morphology and stability in healing bone

Bioactive Materials 2023年第10期28卷 155-166页

作者： Stefan Bruns Diana Krüger Silvia Galli D.C.Florian Wieland jorg u.hammel Felix Beckmann Ann Wennerberg Regine Willumeit-Romer Berit Zeller-Plumhoff Julian Moosmann Institute of Metallic Biomaterials Helmholtz-Zentrum HereonMax-Planck-Str.121502GeesthachtGermany university of Malmo Faculty of OdontologyDepartment of ProsthodonticsCarl Gustafs Vag 34Klerken20506MalmoSweden Institute of Materials Physics Helmholtz-Zentrum HereonMax-Planck-Str.121502GeesthachtGermany university of Gothenburg Institute of OdontologyDepartment of ProsthodonticsMedicinaregatan 12 f41390GoteborgSweden

The microstructural architecture of remodeled bone in the peri-implant region of screw implants plays a vital role in the distribution of strain energy and implant *** present a study in which screw implants made from titanium,polyetheretherketone and biodegradable magnesium-gadolinium alloys were implanted into rat tibia and subjected to a push-out test four,eight and twelve weeks after *** were 4 mm in length and with an M2 *** loading experiment was accompanied by simultaneous three-dimensional imaging using synchrotron-radiation microcomputed tomography at 5μm *** deformation and strains were tracked by applying optical flow-based digital volume correlation to the recorded image *** stabilities measured for screws of biodegradable alloys were comparable to pins whereas non-degradable biomaterials experienced additional mechanical ***-implant bone morphology and strain transfer from the loaded implant site depended heavily on the biomaterial *** implants stimulated rapid callus formation displaying a consistent monomodal strain profile whereas the bone volume fraction in the vicinity of magnesium-gadolinium alloys exhibited a minimum close to the interface of the implant and less ordered strain *** in our data suggest that implant stability benefits from disparate bone morphological properties depending on the biomaterial *** leaves the choice of biomaterial as situational depending on local tissue properties.

关键词： Biodegradable implant materials Bone mechanical testing Implant stability Synchrotron micro-computed tomography imaging Digital volume correlation

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On self-affine tiles that are homeomorphic to a ball

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Science China Mathematics 2024年第1期67卷 45-76页

作者： jorg M.Thuswaldner Shu-Qin Zhang Mathematics and Statistics University of LeobenLeoben 8700Austria School of Mathematics and Statistics Zhengzhou UniversityZhengzhou 450001China

Let M be a 3×3 integer matrix which is expanding in the sense that each of its eigenvalues is greater than 1 in modulus and let D?Z^(3)be a digit set containing|det M|*** the unique nonempty compact set T=T(M,D)defined by the set equation MT=T+D is called an integral self-affine tile if its interior is *** D is of the form D={0,v,...,(|det M|-1)v},we say that T has a collinear digit *** present paper is devoted to the topology of integral self-affine tiles with collinear digit *** particular,we prove that a large class of these tiles is homeomorphic to a closed 3-dimensional ***,we show that in this case,T carries a natural CW complex structure that is defined in terms of the intersections of T with its neighbors in the lattice tiling{T+z:z∈Z^(3)}induced by *** CW complex structure is isomorphic to the CW complex defined by the truncated octahedron.

关键词： self-afine sets tiles and tilings low-dimensional topology truncated octahedron

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鄂尔多斯盆地西缘李105井奥陶系乌拉力克组笔石生物地层研究

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地球学报 2024年

作者：王传尚胡勇 jorg Maletz 危凯古生物与地质环境演化湖北省重点实验室中国地质调查局武汉地质调查中心长江大学资源与环境学院柏林自由大学地质研究所

本文通过对鄂尔多斯盆地西缘李105井奥陶系乌拉力克组的笔石化石的研究,划分出两个笔石生物带,即Nemagraptus gracilis带和Cilmacograptus bicornis带,其时限为桑比期。根据乌拉力克组的沉积学特征,结合最新的岩相古地理研究进展,认为... 详细信息

本文通过对鄂尔多斯盆地西缘李105井奥陶系乌拉力克组的笔石化石的研究,划分出两个笔石生物带,即Nemagraptus gracilis带和Cilmacograptus bicornis带,其时限为桑比期。根据乌拉力克组的沉积学特征,结合最新的岩相古地理研究进展,认为原乌拉力克组的底界以一套特征的砾屑灰岩为标志欠妥,建议将克里摩里组上段的以黑色含笔石页岩为主的地层划归乌拉力克组,新厘定的乌拉力克组在盆地西缘北部露头区内蒙古乌海桌子山一带至少包含了Pterograptus elegans、Didymograptus murchisoni和Nemagraptus gracilis带等三个笔石带,其时限跨越中奥陶世达瑞威尔期晚期到晚奥陶世桑比期早期。可见,乌拉力克组在鄂尔多斯盆地西缘,其顶、底界线均存在明显的穿时。这一发现不仅为乌拉力克组的时限及其相变穿时提供了准确的生物地层约束,也为这一地区岩相古地理的重建及页岩气勘探有利相带的优选提供了依据。

关键词：鄂尔多斯盆地西缘乌拉力克组笔石带穿时李105井

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Spatial distribution,morphology,and risk assessment of microplastics in sediment from the Pearl River Estuary,China

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Emerging Contaminants 2024年第3期10卷 409-418页

作者： Kaiqiang Xu Asfandyar Shahab jorg Rinklebe He Xiao Jieyue Li Feng Ye Yanhong Li Dunqiu Wang Michael S.Bank Gangjian Wei College of Environmental Science and Engineering Guilin University of TechnologyGuilin541004China Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology Guilin541004China university of Wuppertal School of Architecture and Civil EngineeringInstitute of Foundation EngineeringWater-and Waste-ManagementLaboratory of Soil-and Groundwater-ManagementPauluskirchstraße 742285WuppertalGermany Institute of Marine Research 5817BergenNorway university of Massachusetts Amherst AmherstMA01003USA State Key Laboratory of Isotope Geochemistry Guangzhou Institute of GeochemistryChinese Academy of SciencesGuangzhou510640China

Microplastics(MPs)(64.12%)of detected MPs were<0.85 mm and primarily consisted of pellets(36.84%)and fragments(29.65%).Three polymer types of MPs were identified by Fourier Transform Infrared Spectroscopy(FT-IR)includ... 详细信息

Microplastics(MPs)(ulnerable to MP pollution,and assessing their sources,fate,and transport in the environment is imperative for marine ecosystem *** for marine sediment are still limited,particularly in the Pearl River Estuary(PRE)ecosystem in ***,we assessed the abundance,characteristics,and risks of MPs in marine sediment from *** abundance ranged from 2.05×10^(3)items·kg^(-1)to 7.75×10^(3)items·kg^(-1)(dry weight),and white and black MPs were the dominant *** majority(>64.12%)of detected MPs wereurier Transform Infrared Spectroscopy(FT-IR)including polyethylene(PE),polyethylene terephthalate(PET),and polypropylene(PP).Polyurethane(Pu)sponge was reported for the first time in this study *** of the surface morphology of typical MPs using Scanning Electron Microscopy(SEM)showed that all MPs exhibited varying degrees of erosion,characterized by cracks,folds,and bumpy *** on type and quantity of MPs and the polymers identified,we assessed and classified the risk of MP contamination in PRE sediment as category Ⅲ,indicating severe ecosystem *** results may serve as an effective model for other estuaries facing similar pollution regimes and provides valuable information for marine sediment risk assessment.

关键词： Microplastics Distributional characteristics Surface morphology Risk assessment Pearl River Estuary

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Disease networks. uncovering disease-disease relationships through the incomplete interactome

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四川生理科学杂志 2024年第4期46卷 199-199页

作者： jorg Menche Center for Complex Networks Research and Department of Physics Northeastern University 110 Forsyth Street 111 Dana Research Center Boston MA 02115 USA. Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology Dana-Farber Cancer Institute 450 Brookline Avenue Boston MA 02215 USA. Center for Network Science Central European University Nador u. 9 1051 Budapest Hungary. Center for Complex Networks Research and Department of Physics Northeastern University 110 Forsyth Street 111 Dana Research Center Boston MA 02115 USA. Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology Dana-Farber Cancer Institute 450 Brookline Avenue Boston MA 02215 USA. Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology Dana-Farber Cancer Institute 450 Brookline Avenue Boston MA 02215 USA. Department of Genetics Harvard Medical School 77 Avenue Louis Pasteur Boston MA 02115 USA. Department of Medicine Brigham and Women's Hospital Harvard Medical School 75 Francis Street Boston MA 02115 USA. Center for Complex Networks Research and Department of Physics Northeastern University 110 Forsyth Street 111 Dana Research Center Boston MA 02115 USA. Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology Dana-Farber Cancer Institute 450 Brookline Avenue Boston MA 02215 USA. Center for Network Science Central European University Nador u. 9 1051 Budapest Hungary. Department of Medicine Brigham and Women's Hospital Harvard Medical School 75 Francis Street Boston MA 02115 USA. alb@neu.edu.

According to the disease module hypothesis,the cellular components associated with a disease segregate in the same neighborhood of the human interactome,the map of biologically relevant molecular ***,given the incompleteness of the interactome and the limited knowledge of disease-associated genes,it is not obvious if the available data have sufficient coverage to map out modules associated with each disease.

关键词： incomplete interactions. networks.

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Common interacting genetic variation shapes susceptibility to type 1 diabetes in a Colombian Caribbean community:In search of shared genetic markers

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Genes & Diseases 2024年第4期11卷 106-108页

作者： Gloria Garavito-De Egea Alex Dominguez-Vargas jorg e l.Velez Gustavo Aroca Luis Fagng Elkin Navarro-Quiroz Zilac Espitaleta Kenny Del Toro-Camargo Leticia Martinez-Ariza Tatiana Gonzalez-Vargas Susana Garcia Mauricio Arcos-Burgos Eduardo Egea universidad del Norte Division Ciencias de la SaludBarranquillaColombia universidad Simon Bolivar Facultad de Ciencias de la SaludBarranquillaColombia Clinica de la Costa Grupo de Investigacion en NefrologiaBarranquillaColombia universidad de Antioquia Grupo de Investigacion en Psiquiatria(GIPSI)Departamento de PsiquiatriaInstituto de Investigaciones MedicasFacultad de MedicinaMedellinColombia

Genome-wide association studies(GWASs)have identified hundreds of loci across the human genome conferring susceptibility to autoimmune diseases(AIDs),some of which are shared between more than two ***,this univariate ... 详细信息

关键词： susceptibility diseases diabetes

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Bringing epigenetics into the diagnostics of the andrology laboratory： challenges and perspectives

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Asian Journal of Andrology 2014年第5期16卷 669-674,I0006页

作者： Ruth Klaver jorg Gromoll Centre of Reproductive Medicine and Andrology University Clinics of MOnster MOnster Germany

Recent studies have shown significant associations of aberrant DNA methylation in spermatozoa with idiopathic male infertility, increased frequency of spontaneous abortions and imprinting disorders. Thus, the analysis of DNA methylation of specific genes in spermatozoa has the potential to become a new valuable diagnostic marker in clinical andrology. This perspective article discusses the current state and value of DNA methylation analysis in the diagnostic setup of infertile men and outlines challenges and perspectives. It highlights the potential of DNA methylation in andrological diagnostics and its putative benefit in the examination of hitherto idiopathic infertile patients is described.

关键词： DNA methylation male infertility spermatogenesis

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Transfer of CrylAc and Cry2Ab proteins from genetically engineered Bt cotton to herbivores and predators

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Insect Science 2018年第5期25卷 823-832页

作者： Michael Meissle jorg Romeis Agroscope Research Division Agroecology and Environment Zurich Switzerland

With the cukivation of Bt cotton, the produced insecticidal Cry proteins are ingested by herbivores and potentially transferred along the food chain to natural enemies, such as predators. In laboratory experiments with Bollgard II cotton, concentrations of CrylAc and Cry2Ab were measured in Lepidoptera larvae （Spodoptera littoralis, Hello- this virescens）, plant bugs （Euschistus heros）, aphids （Aphis gossypii）, whiteflies （Bemisia tabaci）, thrips （ Thrips tabaci, Frankliniella occidentalis）, and spider mites （Tetranychus urticae）. Tritrophic experiments were conducted with caterpillars ofS. littoralis as prey and larvae of ladybird beetles （Harmonia axyridis, Adalia bipunctata） and lacewings （Chrysop- erla carnea） as predators. Immunological measurements （ELISA） indicated that herbivores feeding on Bt cotton contained 5%-50% of the Bt protein concentrations in leaves except whiteflies and aphids, which contained no or only traces of Bt protein, and spider mites, which contained 7 times more Cry 1Ac than leaves. Similarly, predators contained 1%-30% of the Cry protein concentration in prey. For the nontarget risk assessment, this indicates that Bt protein concentrations decrease considerably from one trophic level to the next in the food web, except for spider mites that contain Bt protein concentrations higher than those measured in the leaves. Exposure of phloem sucking hemipterans is negligible.

关键词： arthropod food web Bacillus thuringiensis Bt cotton Cry protein ELISA transgenic plants

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Fundamental influences of particles on stirred and unstirred venting processes of foaming systems

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Frontiers of Chemical Science and Engineering 2014年第2期8卷 141-148页

作者： Henrik LEIMEISTER jorg STEINBACH Department of Process Engineering Technische Universitat Berlin Strage des 17. Juni 135 10623 Berlin Germany

Venting is the common safety measure to protect plant equipment against excessive overpressure. So far, scenarios in which particles were part of the system and should have been accounted for did ignore their presence; the scenarios were treated like a two-phase system. Current research shows that particles can have a major influence on the venting behaviour. Experimental results indicate that particles affect level swell and relief flow especially of foamy systems. Based on those results four different layers of influence of the particle have been identified and are presented in a first model. Based on this model recommendations for the development of new and more complex models are given.

关键词： venting multi-phase

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The contribution of small leaks in a baghouse filter to dust emission in the PM2.s range-A system approach

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Particuology 2017年第1期15卷 40-52页

作者： Oliver Kurtz jorg Meyer Gerhard Kasper Institut for Mechanische Verfahrenstechnik und Mechanik Karlsruhe Institute of Technology 76131 Karlsruhe Germany Freudenberg Filtration Technologies 69465 WeinheimGermany.

The contribution of leakage in a baghouse filter （defined as a short circuit between the upstream and downstream sides of the filter） to the emission of fine particles is quantified in comparison to other dust emission sources, and the influence of key operating variables on overall system response is analyzed. The study was conducted on a well-maintained pilot-scale filter unit （9 bags of 500 g/m^2 calendered polyester needle felt; total surface area 4.2 m^2） operated in Ap-controlled mode over a range of pulsing intensities, with two types of test dust （one free-flowing and the other cohesive） at inlet concentrations of 10 and 30 g/m^3. Leaks included single holes between 0.5 and 4 mm diameter, intentionally placed in either the plenum plate or one of the filter bags, as well as seamlines from bag confectioning. Emissions were sep- arated by source into a transient contribution due to dust penetration through the filter bags after each cleaning pulse, and a continuous contribution from leaks. This separation was based on a novel method of data processing that relies on time-resolved concentration measurements with a specially calibrated optical particle counter. Tiny leaks on the order of 1 mm generated the same emission level as all the bags combined, and dominated continuous emissions. The equivalent leak cross section （leakage = media emission） was about 1 ppm of the total installed filter surface, independent of upstream dust concentra- tion. Leakage through open seamlines amounted to 75% of media emissions in case of free-flowing test dust. Leakage was restricted to aerodynamic diameters less than ~5 μm （roughly the PM2.s mass frac- tion）. For comparison, time-averaged mass penetration through conventional needle-felt media ranged from about 10^-5 to 10^-6, depending on cohesiveness of the particle material and pulse cleaning intensity, giving emission levels between about 0.02 and 0.2 mg/m^3 at the reference concentration of 10 R/m^2.

关键词： Air filtration Baghouse Pulse-cleaned filters Leaks PM2.5 Dust emission

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