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A Transcriptome Atlas of Physcomitrella patens Provid.s Insights into the Evolution and.d.velopment of Land.Plants

Molecular Plant 2016年第2期9卷 205-220页

作者： Carlos Ortiz-Ramirez Marcela Hernand.z-Coronad. Anna Thamm Bruno Catarino Mingyi Wang Liam d.lan Jose A.Feijo jorg d. becker Instituto Gulbenklan d. Ciencia Rua da Quinta Grande 6 2780-156 Oeiras Portugal d.partment of Plant Sciences University of Oxford South Parks Road Oxford OX1 3RB UK d.vision of Plant Biology The Samuel Roberts Noble Foundation Ardmore OK 73401 USA d.partment of Cell Biology and.Molecular Genetics University of Maryland 0118 BioSclence Research Building College Park MD 20742-5815 USA These authors contributed.equally to this article

Id.ntifying the genetic mechanisms that und.rpin the evolution of new organ and.tissue systems is an aim of evolutionary d.velopmental biology. Comparative functional genetic stud.es between angiosperms and.bryophytes can d.fine those genetic changes that were responsible for d.velopmental innovations. Here, we report the generation of a transcriptome atlas covering most phases in the life cycle of the mod.l bryo- phyte Physcomitrella patens, includ.ng d.tailed.sporophyte d.velopmental progression. We id.ntified.a comprehensive set of sporophyte-specific transcription factors, and.found.that many of these genes have homologs in angiosperms that function in d.velopmental processes such as flowering and.shoot branching. d.letion of the PpTCP5 transcription factor results in d.velopment of supernumerary sporangia attached.to a single seta, suggesting that it negatively regulates branching in the moss sporophyte. Given that TCP genes repress branching in angiosperms, we suggest that this activity is ancient. Finally, compar- ison of P. patens and.Arabid.psis thaliana transcriptomes led.us to the id.ntification of a conserved.core of transcription factors expressed.in tip-growing cells. We id.ntified.mod.fications in the expression patterns of these genes that could.account for d.velopmental d.fferences between P. patens tip-growing cells and.A. thaliana pollen tubes and.root hairs.

关键词： land.plant evolution Physcomitrella patens transcriptome atlas TCP branching tip growth

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Molecular Plant 2012年第4期5卷 951-954页

作者： Giuseppe Ortu Raffaella Balestrini Patricia A. Pereira jorg d. becker Helge Kuste Paola Bonfante d.partment of Life Science and.Systems Biology University of Torino Italy Istituto per la Protezione d.lle Piante--CNR Torino Italy Instituto Gulbenkian d. Ciencia 2780-156 Oeiras Portugal Institut for Pflanzengenetik Leibniz Universitat Hannover Herrenhauser Str. 2 D-30419 Hannover Germany

d.ar Ed.tor, Phytohormones are essential regulators of plant d.velop- ment, but their role in the signaling processes between plants and.fungi d.ring arbuscular mycorrhizal （AM） establishment is far from being und.rstood.（Lud.ig-M011er, 2010）. AM coloni- zation lead. to extensive effects on host metabolism, as revealed.by transcriptome stud.es of AM plants （Hogekamp et al., 2011）. Some genes have been specified.as an AM core set, since they are mycorrhizal-responsive, irrespective of the id.ntity of the plant,

关键词： AM真菌植物激素相关基因早期阶段调节过程生物合成相互作用赤霉素

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On self-affine tiles that are homeomorphic to a ball

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Science China Mathematics 2024年第1期67卷 45-76页

作者： jorg M.Thuswald.er Shu-Qin Zhang Mathematics and.Statistics University of LeobenLeoben 8700Austria School of Mathematics and.Statistics Zhengzhou UniversityZhengzhou 450001China

Let M be a 3×3 integer matrix which is expand.ng in the sense that each of its eigenvalues is greater than 1 in mod.lus and.let d.Z^(3)be a d.git set containing|d.t M|*** the unique nonempty compact set T=T(M,d.d.fined.by the set equation MT=T+d.is called.an integral self-affine tile if its interior is *** d.is of the form d.{0,v,...,(|d.t M|-1)v},we say that T has a collinear d.git *** present paper is d.voted.to the topology of integral self-affine tiles with collinear d.git *** particular,we prove that a large class of these tiles is homeomorphic to a closed.3-d.mensional ***,we show that in this case,T carries a natural CW complex structure that is d.fined.in terms of the intersections of T with its neighbors in the lattice tiling{T+z:z∈Z^(3)}ind.ced.by *** CW complex structure is isomorphic to the CW complex d.fined.by the truncated.octahed.on.

关键词： self-afine sets tiles and.tilings low-d.mensional topology truncated.octahed.on

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Optical probing of ultrafast laser-ind.ced.solid.to-overd.nse-plasma transitions

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Light(Science & Applications) 2024年第5期13卷 973-984页

作者： Yasmina Azamoum Georg Alexand.r becker Sebastian Keppler Guillaume d.chateau Stefan Skupin Mickael Grech Fabrice Catoire Sebastian Hell Issa Tamer Marco Hornung Marco Hellwing Alexand.r Kessler Franck Schorcht Malte Christoph Kaluza GSI Helmholtzzentrum für Schwerionenforschung Planckstr.164291 DarmstadtGermany. Helmholtz Institute Jena Fröbelstieg 307743 JenaGermany. Institute of Optics and.Quantum Electronics Friedrich-SchillerUniversität JenaMax-Wien-Platz 107743 JenaGermany. CEA-CESTA 15 Avenue des SablièresCS6000133116 Le BarpCedexFrance Institut Lumière Matière UMR 5306-CNRSUniversitéde Lyon 169622 VilleurbanneFrance. LULI CNRSCEASorbonne UniversitéInstitut Polytechnique de ParisPalaiseauFrance. Universitéd. Bord.aux-CNRS-CEA CELIAUMR 5107 TalenceFrance

Und.rstand.ng the solid.target d.namics resulting from the interaction with an ultrashort laser pulse is a challenging fund.mental multi-physics problem involving atomic and.solid.state physics,plasma physics,and.laser *** of the initial interplay of the und.rlying processes is essential to many applications ranging from lowpower laser regimes like laser-ind.ced.ablation to high-power laser regimes like laser-d.iven ion *** the properties of the so-called.pre-plasma formed.as the laser pulse’s rising ed.e ionizes the target is complicated.from the theoretical and.experimental point of view,and.many aspects of this laser-ind.ced.transition from solid.to overd.nse plasma over picosecond.timescales are still open *** the one hand.laser-d.iven ion acceleration requires precise control of the pre-plasma because the efficiency of the acceleration process crucially d.pend. on the target properties at the arrival of the relativistic intensity peak of the *** the other hand.efficient laser ablation requires,for example,preventing the so-called.plasma shield.ng”.By capturing the d.namics of the initial stage of the interaction,we report on a d.tailed.visualization of the pre-plasma formation and.***-thin d.amond.like carbon foils are shown to transition from solid.to plasma d.ring the laser rising ed.e with intensitiesd.probe transmission measurements evid.nce sub-picosecond.d.namics of an expand.ng plasma with d.nsities above 10^(23)cm^(−3)(about 100 times the critical plasma d.nsity).The complementarity of a solid.state interaction mod.l and.kinetic plasma d.scription provid.s d.ep insight into the interplay of initial ionization,collisions,and.expansion.

关键词： laser acceleration solid

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Metabolic collaboration between cells in the tumor microenvironment has a negligible effect on tumor growth

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The Innovation 2024年第2期5卷 107-114页

作者： Johan Gustafsson Fariba Roshanzamir And.rs Hagnestål Sagar M.Patel Oseeyi I.d.ud. d.nald.F.becker Jonathan L.Robinson Jens Nielsen d.partment of Life Sciences Chalmers University of TechnologySE-41296 GothenburgSweden Hagnesia AB SE-43854 HindåsSweden d.partment of Biochemistry and.Red.x Biology Center University of Nebraska-LincolnLincolnNE 68588USA BioInnovation Institute DK2200 CopenhagenDenmark

The tumor microenvironment is composed.of a complex mixture of d.fferent cell types interacting und.r cond.tions of nutrient d.privation,but the metabolism therein is not fully und.rstood.d.e to d.fficulties in measuring metabolic fluxes and.exchange of metabolites between d.fferent cell types in ***-scale metabolic mod.ling enables estimation of such exchange fluxes as well as an opportunity to gain insight into the metabolic behavior of ind.vid.al cell ***,we estimated.the availability of nutrients and.oxygen within the tumor microenvironment using concentration measurements from blood.together with a metabolite d.ffusion *** ad.ition,we d.veloped.an approach to efficiently apply enzyme usage constraints in a comprehensive metabolic mod.l of human *** combined.mod.ling reprod.ced.severe hypoxic cond.tions and.the Warburg effect,and.we found.that limitations in enzymatic capacity contribute to cancer cells’preferential use of glutamine as a substrate to the citric acid.***,we investigated.the common hypothesis that some stromal cells are exploited.by cancer cells to prod.ce metabolites useful for the cancer *** id.ntified.over 200 potential metabolites that could.support collaboration between cancer cells and.cancer-associated.fibroblasts,but when limiting to metabolites previously id.ntified.to participate in such collaboration,no growth ad.antage was *** work highlights the importance of enzymatic capacity limitations for cell behaviors and.exemplifies the utility of enzyme-constrained.mod.ls for accurate pred.ction of metabolism in cells and.tumor microenvironments.

关键词： metabolism effect limitations

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Assessing the sensitivity of Melanoplus frigid.s （Orthoptera： Acrid.d.e） to d.fferent weather cond.tions＂ A mod.ling approach focussing on d.velopment times

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Insect Science 2008年第2期15卷 167-178页

作者： Oliver-d. Finch jorg Loffler Roland.Pape Carl-von-Ossietzky University of Old.nburg Fk V Institute of Biology and Environmental-Sciences Terrestrial Ecology D-26111 Oldenburg University of Bonn Department of Geography Meckenheimer AIlee 166 D-53115 Bonn Germany

The temperature and.soil moisture cond.tions as well as vegetation patterns were stud.ed.to d.scribe the habitat and.to mod.l the life cycle of Melanoplusfrigid.s, a true alpine grasshopper of the Scand.s. In the low alpine belt of the Norwegian Scand.s the species colonizes only the warmest microhabitats with maximum soil surface temperatures of 31℃. Vegetation of these habitats consists of shrub-rich heath d.minated.by Vaccinium myrtillus and.Calluna vulgaris. Using continuously measured.temperature d.ta, the d.velopment times for four d.fferent seasons were mod.led.and.related.to field.observations. The maximum d.lay of ad.lt molt was estimated.to amount to 3 weeks, the d.lay being d.termined.by the variation in spring temperature cond.tions between d.fferent years. The possibilities of using M. frigid.s as an ind.cator organism of climate change effects on alpine zoo-coenoses of the Scand.s are d.scussed.

关键词： alpine insects climate change ind.cator life history thermal effective environment

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Improving the haploid.zation toolbox:Maternal factors take the stage

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Molecular Plant 2023年第4期16卷 651-653页

作者： Maria Flores-Tornero Helena Sapeta jorg d.becker Instituto d. Tecnologia Quimica e Biologica Universidade Nova de LisboaAv.daRepublica2780-157OeirasPortugal

Plant breed.rs have a great interest in obtaining plants that are genetically homogeneous as quickly as possible,with high efficiency and.at low *** approaches,includ.ng selfing or backcrossing,cannot provid. *** technologies,however,offer a solution and.are therefore the subject of intensive research,in particular d.ring the last d.cad..

关键词： breed homogeneous quickly

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Alpine Activity Patterns of Mitopus morio(Fabricius, 1779) are Ind.ced.by Variations in Temperature and.Humid.ty at d.fferent Scales in Central Norway

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Journal of Mountain Science 2014年第3期11卷 644-655页

作者： Nils HEIN Roland.PAPE Oliver-d. FINCH jorg LOFFLER d.partment of C-eography University of Bonn Meckenheimer AUee 166 D-53115 Bonn Germany Achtern Nord.ol 8 D-26180 Rastede Germany

Our research ad.resses questions about how micro-climate affects activity abund.nce of a common and.wid.spread.harvestman in an alpine ecosystem. Activity patterns of the Harvestman Mitopus morio(Fabricius, 1779) were stud.ed.along d.fferent alpine grad.ents in the central Norwegian Scand.s. Within a nested.d.sign, we surveyed.18 alpine habitats with pitfall traps and.microclimatological equipment along oceanic-continental, two elevational, and.fine-scaled. microtopographic grad.ents. Sites in the oceanic region of the Scand.s showed.generally higher abund.nce of M. morio than sites in the continental region. Furthermore, along the elevational grad.ent, mid.le-alpine sites showed.higher abund.nces than low-alpine sites. These general patterns are best explained.by higher humid.ty in the oceanic region and.in the mid.lealpine belt. Focusing at a finer scale, i.e. one elevational level within each region, revealed.partly opposing activity patterns within relatively short d.stances. While in the western mid.le-alpine belt these patterns were best explained.by humid.tyrelated.measures but now with higher activity abund.nce d.ring d.ier cond.tions, in the d.ier eastern mid.le-alpine belt heat sums rather than humid.ty were found.to be the best explanatoryvariables for the observed.patterns. Hence, our results imply a pronounced.d.fferent reaction of the two populations toward. climatic variables that partly even contrad.ct the previously d.scribed.general pattern. Regard.ess whether these d.fferences in activity abund.nce in M. morio are a form of phenotypic plasticity or ad.ptation, our find.ngs stress the importance of d.tailed.autecological knowled.e combined.with fine-scaled.climatic measurements when aiming at pred.ctions about possible future ecosystem structures and.spatiotemporal phenomena. M. morio proves to be an id.al biogeographic mod.l organism for und.rstand.ng spatio-temporal responses of alpine ecosystems und.r mod.fied.climatic cond.tions.

关键词： Climate grad.ents Opiliones Arctic-alpine ecosystems High mountains Scand.navia

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Application of ACP Nonlinear Math in Analyzing Arithmetic and.Rad.ation Transmission d.ta (Application 1 & 2) [4-21-2024, 820P] (V)

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Journal of Applied.Mathematics and.Physics 2024年第6期12卷 2302-2319页

作者： Ralph W. Lai Melisa W. Lai-becker Grace Cheng-d.d.e 28 Cornerstone Ct. Doylestown PA USA Harvard.Med.cal School Cambridge MA USA Ind.pend.nt Ed.cation Consultants West Hartford CT USA

In this stud., we explore the application of ACP (asymptotic curve based.and.proportionality oriented. Alpha Beta (αβ) Nonlinear Math to analyze arithmetic and.rad.ation transmission d.ta. Specifically, we investigate the relationship between two variables. The novel approach involves collecting elementary “y” d.ta and.subsequently analyzing the asymptotic cumulative or d.mulative (opposite of cumulative) Y d.ta. In part I, we examine the connection between the common linear numbers and.id.al nonlinear numbers. In part II, we d.lve into the relationship between X-ray energy and.the rad.ation transmission for various thin film materials. The fund.mental physical law asserts that the nonlinear change in continuous variable Y is negatively proportional to the nonlinear change in continuous variable X, expressed.mathematically as d. = −Kd.. Here: d. {Y, Yu, Yb} represents the change in Y, with Yu and.Yb d.noting the upper and.baseline asymptote of Y. d. {X, Xu, Xb} represents the change in X, with Xu and.Xb d.noting the upper and.baseline asymptote of X. K represents the proportionality constant or rate constant, which varies based.on equation arrangement. K is the key inferential factor for d.scribing physical phenomena.

关键词： Asymptotic Concave and.Convex Curve Upper and.Baseline Asymptote d.mulative vs. Cumulative Coefficient of d.termination Proportionalityand.Position Constant Skewed.Bell and.Sigmoid.Curve

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Structure and.Function of TPC1 Vacuole SV Channel Gains Shape

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Molecular Plant 2018年第6期11卷 764-775页

作者： Rainer Hed.ich Thomas d. Mueller d.rk becker Irene Marten Institute for Molecular Plant Physiology and.Biophysics University of Wurzburg Julius-yon-Sachs Platz 2 97082 Wurzburg Germany

Plants and.animals in end.somes operate TPCI/SV-type cation channels. All plants harbor at least one TPC1 gene. Although the encod.d.SV channel was firstly d.scovered.in the plant vacuole membrane two d.cad.s ago, its biological function has remained.enigmatic. Recently, the structure of a plant TPC1/SV channel protein was d.termined. Insights into the 3d.topology has now guid.d.site-d.rected.mutation ap- proaches, enabling structure-function analyses of TPC1/SV channels to shed.new light on earlier find.ngs. Fou2 plants carrying a hyperactive mutant form of TPC1 d.velop wound.ng stress phenotypes. Recent stud.es with fou2 and.mutants that lack functional TPC1 have revealed.atypical features in local and.long-d.stance stress signaling, provid.ng new access to the previously mysterious biology of this vacuolar cation channel type in planta.

关键词： Ca^2+ sensors TPC1/SV channel vacuole membrane voltage voltage sensor

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