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Genome-wide association study identifies QTL for eight fruit traits in cultivated tomato (Solanum lycopersicum L.)

Horticulture Research 2021年第1期8卷 2698-2707页

作者： Minkyung Kim Thuy Tien Phan Nguyen joon-hyung ahn Gi-Jun Kim Sung-Chur Sim Department of Bioresources Engineering Sejong UniversitySeoulRepublic of Korea Asia Seed R&D center IcheonRepublic of Korea Plant Engineering Research Institute Sejong UniversitySeoulRepublic of Korea

Genome-wide association study(GWAS)is effective in identifying favorable alleles for traits of interest with high mapping resolution in crop *** this study,we conducted GWAS to explore quantitative trait loci(QTL)for eight fruit traits using 162 tomato accessions with diverse genetic *** eight traits included fruit weight,fruit width,fruit height,fruit shape index,pericarp thickness,locule number,fruit firmness,and *** variations of these traits in the tomato collection were evaluated with three replicates in field trials over three *** filtered 34,550 confident SNPs from the 51K Axiom®tomato array based on5%of minor allele frequency for association *** 162 tomato accessions were divided into seven clusters and their membership coefficients were used to account for population structure along with a kinship *** identify marker-trait associations(MTAs),four phenotypic data sets representing each of three years and combined were independently analyzed in the multilocus mixed model(MLMM).A total of 30 significant MTAs was detected over data sets for eight fruit traits at P<*** number of MTA per trait ranged from one(brix)to seven(fruit weight and fruit width).Two SNP markers on chromosomes 1 and 2 were significantly associated with multiple traits,suggesting pleiotropic effects of ***,16 of 30 MTAs suggest potential novel QTL for eight fruit *** results facilitate genetic dissection of tomato fruit traits and provide a useful resource to develop molecular tools for improving fruit traits via marker-assisted selection and genomic selection in tomato breeding programs.

关键词： breeding traits membership

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Fibrinogen’s potential role in connecting cerebrovascular abnormalities with glymphatic dysfunction in Alzheimer’s disease

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Neural Regeneration Research 2025年第1期20卷 203-204页

作者： Vishal Singh Arnab Choudhury hyung Jin ahn Department of Pharmacology Physiology and NeurosciencesRutgers-New Jersey Medical SchoolNewarkNJUSA Brain Health Institute Rutgers UniversityPiscatawayNJUSA

Alzheimer’s disease(AD)stands out as the primary manifestation of age-related dementia,portraying a chronic neurodegenerative disorder distinguished by the accumulation of fibrillar amyloid-β(Aβ)plaques and neurofibrillary tangles of hyperphosphorylated ***,from a clinical standpoint,AD presents itself as a complex condition with a spectrum of dysfunctions rather than a singular pathological *** often-overlooked aspect of the disease is the presence of extensive cerebrovascular abnormalities,given that the majority of AD patients experience altered cerebral blood flow,damaged vasculature,increased microinfarcts and *** models of AD further support this observation,showing cerebrovascular dysfunction such as impaired cerebral blood flow and altered cerebrovascular reactivity(Tataryn et al.,2021;Gareau et al.,2023).

关键词： cerebrovascular dysfunction Alzheimer

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Maximizing biomass utilization: An integrated strategy for coproducing multiple chemicals

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Journal of Energy Chemistry 2025年第1期100卷 180-191页

作者： Byeongchan ahn Sua Jo Jonggeol Na J.Jay Liu Young-Ju Kim Wangyun Won Department of Chemical and Biological Engineering Korea University Department of Chemical Engineering (Integrated process) Kyung Hee University Department of Chemical Engineering and Materials Science Ewha Womans University Department of Chemical Engineering Pukyong National University Resources Engineering Plant Research Department Korea Institute of Geoscience and Mineral Resources

Lignocellulosic biomass is one of the viable solutions to alleviate the global warming. However, the limited utilization of biomass majorly focused on cellulose and hemicellulose restricts the economic and environmental feasibilities. To cope with this issue, we proposed an integrated process of co-producing 1,6-hexanediol（1,6-HDO） with tetrahydrofuran and adipic acid from biomass, referred to as Strategy A. To compare the impacts of lignin upgrading and feedstock, Strategy B, which co-produces tetrahydrofuran alone, and Strategy C, which is the traditional route to produce 1,6-HDO from fossil fuels, were used. Heat networks are also designed to reduce operating costs and indirect carbon emissions due to energy consumption, saving 87% and 83% of the heat and cooling requirements, respectively, in Strategy A. The market competitiveness of Strategy A was evaluated by determining the minimum selling price through techno-economic analysis, and sustainability was thoroughly investigated by quantifying the environmental impacts through both midpoint and endpoint life-cycle assessments（LCAs）.Strategy A was found to be the most favorable both economically（USRDSCHARDOLLAR3,402/ton） and environmentally（-26.9 kg CO2eq.）. This indicates that lignin valorization is not only economically but also environmentally preferred. Finally, changes in economic and environmental feasibilities depending on economic, process, and environmental parameters were investigated using sensitivity and uncertainty analyses. The results of these analyses provide valuable insight into bio-based chemical production.

关键词： Biorefinery Carbon mitigation Climate change Global warming Lignin utilization Bioeconomy

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Prominent cycling reversibility and kinetics enabled by CaTiO3 protective layer on Zn metal for aqueous Zn-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 245-258页

作者： Gaeun Lee Yong Nam ahn Seongjoon So Chanwoo Park Jong-Seong Bae Taehyun Park Il Tae Kim Jaehyun Hur School of Chemical Biological and Battery Engineering Gachon University Seongnam Busan Center Korea Basic Science Institute

Aqueous Zn-ion batteries （AZIBs） have received considerable attention owing to their various advantages such as safety,low cost,simple battery assembly conditions,and high ionic ***,they still suffer from serious problems,including uncontrollable dendrite growth,corrosion,hydrogen evolution reaction （HER） from water decomposition,electrode passivation,and unexpected *** creation of a uniform artificial nanocrystal layer on the Zn anode surface is a promising strategy for resolving these ***,we propose the use of a perovskite CaTiO3（CTO） protective layer on Zn（CTO@Zn） as a promising approach for improving the performance of *** CTO artificial layer provides an efficient pathway for Zn ion diffusion towards the Zn metal because of the high dielectric constant （εr=180） and ferroelectric characteristics that enable the alignment of dipole moments and redistribute the Zn2+ions in the CTO *** avoiding the direct contact of the Zn anode with the electrolyte solution,the uneven dendrite growth,corrosion,parasitic side reactions,and HER are mitigated,while CTO retains its mechanical and chemical robustness during ***,CTO@Zn demonstrates an improved lifespan in a symmetric cell configuration compared with bare ***@Zn shows steady overpotential （～68 m V） for 1500 h at 1 mA cm-2/0.5 mA h cm-2,excelling bare ***,when paired with the V2O5-C cathode,the CTO@Zn//V2O5-C full battery delivers 148.4 mA h g-1（based on the mass of the cathode） after 300 *** study provides new insights into Zn metal anodes and the development of high-performance AZIBs.

关键词： Artificial layer Dielectric constant Zn metal anode Zinc aqueous battery

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Efficient construction of provably secure steganography under ordinary covert channels

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Science China(Information Sciences) 2012年第7期55卷 1639-1649页

作者： ahn Gail-joon School of Computing Informaticsand Decision Systems EngineeringArizona State University

Steganography is the science of hiding information within seemingly harmless messages or innocent *** paper addresses the problems of efficient construction of secure steganography in ordinary covert *** relying on any sampling assumption,we provide a general construction of secure steganography under computational *** results show that unpredictability of mapping function in covertext sampler is indispensable for secure stegosystem on indistinguishability against adaptive chosen hiddentext *** completely prove that computationally secure steganography can be constructed on pseudorandom function and unbiased sampling function under ordinary covert channels,that is,its security is inversely proportional to the sum of errors of these two functions,as well as the legth of *** importantly,our research is not dependent upon pseudorandom ciphertext assumption of cryptosystem or perfect sampling ***,our results are practically useful for construction and analysis of secure stegosystems.

关键词： steganography cryptography indistinguishability sampler unpredictability adversary models

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Zero-knowledge proofs of retrievability

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Science China(Information Sciences) 2011年第8期54卷 1608-1617页

作者： ahn Gail-joon School of Computing Informatics and Decision Systems Engineering Arizona State University

Proof of retrievability (POR) is a technique for ensuring the integrity of data in outsourced storage *** this paper,we address the construction of POR protocol on the standard model of interactive proof *** propose the first interactive POR scheme to prevent the fraudulence of prover and the leakage of verified *** also give full proofs of soundness and zero-knowledge properties by constructing a polynomial-time rewindable knowledge extractor under the computational Diffie-Hellman *** particular,the verification process of this scheme requires a low,constant amount of overhead,which minimizes communication complexity.

关键词： cryptography integrity of outsourced data proofs of retrievability interactive protocol zero- knowledge soundness rewindable knowledge extractor

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The Characteristics of CLHS Driving for High Luminance Efficiency in AC PDP

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Plasma Science and Technology 2016年第11期18卷 1116-1122页

作者： Gun-Su KIM Chi-hyung ahn Seok-Hyun LEE Department of Electrical and Electronic Engineering Youngsan UniversityYangsanGyeongnam 50510Korea Korea Railroad Research Institute Uiwang Gyeonggi 16105Korea School of Electrical Engineering Inha UniversityIncheon 22212Korea

This paper proposes a CLHS （Capacitor Less Half Sustain） driving method that is applied to a long gap panel to reduce the power consumption. In order to reduce the power consumption in moving images, the luminous efficiency should be improved at the low discharge load （〈25%）. The weight of reactive power consumption tends to increase as the low discharge load decreases. Thus, it is very important to improve the luminous efficiency at low discharge load. It is well known that a long gap panel improves the luminance and the luminous efficiency but it is very difficult to drive the panel due to high driving voltage. It is confirmed that the main factors which cause a long gap panel to increase the minimum driving voltages are not only a long discharge gap but also self-erasing discharge. Self-erasing discharge is generated between the address and sustain electrodes in a sustain period. The CLHS driving method can reduce the reactive power consumption in a sustain period because energy recovery capacitors were removed in the sustain circuit. The CLHS driving method can reduce the minimum driving voltage of the long gap panel because the self-erasing discharge was prevented. When the CLHS driving method was applied to the panel with an ITO gap of 100 μm, Vs and VA minimum voltages are reduced by about 9 V and 12 V compared with those of the normal driving method. The luminance and the luminous efficiency also increased by about 24.3% and 33.3% at the discharge load of 4% compared with those at the normal condition.

关键词： PDP plasma long gap CLHS

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A note on circle packing

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Journal of Zhejiang University-Science C(Computers and Electronics) 2012年第8期13卷 559-564页

作者： Young joon ahn Christoph M. HOFFMANN Paul ROSEN Department of Mathematics Education Chosun University Gwangju 501-759 Korea Department of Computer Science Purdue University West Lafayette IN 47907 USA Scientific Computing and Imaging Institute University of Utah Salt Lake City UT 84112 USA

The problem of packing circles into a domain of prescribed topology is considered. The circles need not have equal radii. The Collins-Stephenson algorithm computes such a circle packing. This algorithm is parMlelized in two different ways and its performance is reported for a triangular, planar domain test case. The implementation uses the highly parallel graphics processing unit （GPU） on commodity hardware. The speedups so achieved are discussed based on a number of experiments.

关键词： Circle packing Algorithm performance Parallel computation Graphics processing unit (GPU)

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High-efficiency design of a mixed-flow pump

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Science China(Technological Sciences) 2010年第1期53卷 24-27页

作者： KIM Jin-Hyuk ahn hyung-Jin KIM Kwang-Yong Department of Mechanical Engineering Inha University253Yonghyun-DongIncheon402-751Republic of Korea Industrial Machinery Division Iljin Electric Co.Ltd5-5Hwasu-DongIncheon401-020Republic of Korea

High-efficiency design of a mixed-flow pump has been carried out based on numerical analysis of a three-dimensional viscous *** analysis,the Reynolds-averaged Navier-Stokes equations with a shear stress transport turbulence model were discretized by finite-volume *** grid system was constructed in the computational domain,which has O-type grids near the blade surfaces and H/J-type grids in other *** numerical results were validated with experimental data for the heads and hydraulic efficiencies at different flow *** hydraulic efficiency at the design flow coefficient was evaluated with variation of the geometric variables,i.e.,the area of the discharge and length of the vane in the *** result has shown that the hydraulic efficiency of a mixed-flow pump at the design condition is improved by the modification of the geometry.

关键词： mixed-flow pump numerical analysis impeller vane diffuser head hydraulic efficiency

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Smad3 and its phosphoisoforms are prognostic predictors of hepatocellular carcinoma after curative hepatectomy

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Hepatobiliary & Pancreatic Diseases International 2012年第1期11卷 51-59页

作者： Seok-hyung Kim Soomin ahn Cheol-Keun Park Department of Pathology Samsung Medical CenterSungkyunkwan University School of Medicine

BACKGROUND:Progression of hepatocellular carcinoma (HCC) often leads to vascular invasion and intrahepatic metastasis,which correlate with recurrence after surgical treatment and poor *** may be an unusual cancer affected by continuous inflammation that can lead to consistent upregulation of transforming growth factor-β (TGF-β).Chronic inflammation shifts hepatocytic TGF-β signaling from the tumor-suppressive pSmad3C pathway to the oncogenic pSmad3L *** this study,we investigated the functional roles of Smad3 and its phosphoisoforms in the progression of ***:Tumor tissue microarrays of samples from 272 HCC patients who underwent curative surgical resection were used to detect the expression of Smad3,Smad4,pSmad3C (S423/425),pSmad3L (T179),pSmad3L (S204),and pSmad3L (S213).Disease-specific death was defined as 1) tumor occupying more than 80% of the liver,2) portal venous tumor thrombus (PVTT) proximal to the second bifurcation,3) obstructive jaundice due to tumor,4) distant metastases,or 5) variceal hemorrhage with PVTT proximal to the first *** the time of analysis,tumor recurrence was detected in 184 (67.6%) patients,and 96 (35.3%) had died of ***:Nuclear and cytoplasmic localization of Smad3,and nuclear localization of Smad4 were observed in 18.0%,9.9%,and 9.2% of HCCs,*** rates of Smad3 phosphoisoform-immunoreactive HCC varied according to the location of phosphorylation:pSmad3C (S423/425) 8.1%,pSmad3L (T179) 2.6%,pSmad3L (S204) 2.2%,and pSmad3L (S213) 10.3%.Multivariate analyses revealed that pSmad3C (S423/425) (P=0.022) was an independent predictor of longer recurrence-free ***3L (S213) (P=0.006),intrahepatic metastasis,multicentric occurrence,and liver cirrhosis were independent predictors of shorter recurrence- free *** Smad3 (P=0.006),larger tumor size,and intrahepatic metastasis were independent predictors of shorter disease-specific *** pSmad3L (S213) did not sh

关键词： Smad3 pSmad3C (S423/425) pSmad3L (S213) hepatocellular carcinoma hepatectomy survival

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