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Preparation of human decellularized peripheral nerve allograft using amphoteric detergent and nuclease

Neural Regeneration Research 2021年第9期16卷 1890-1896页

作者： joo-Yul Bae Suk young Park young Ho Shin Shin Woo Choi Jae Kwang Kim Department of Orthopedic Surgery University of Ulsan College of MedicineGangneung Asan HospitalGangneung-siKorea Department of Orthopedic Surgery University of Ulsan College of MedicineAsan Medical CenterSeoulKorea

Animal studies have shown that amphoteric detergent and nuclease(Dnase I and ribonuclease A) is the most reliable decellularization method of the peripheral nerve. However, the optimal combination of chemical reagents for decellularization of human nerve allograft needs further investigation. To find the optimal protocol to remove the immunogenic cellular components of the nerve tissue and preserve the basal lamina and extracellular matrix and whether the optimal protocol can be applied to larger-diameter human peripheral nerves, in this study, we decellularized the median and sural nerves from the cadavers with two different methods: nonionic and anionic detergents(Triton X-100 and sodium deoxycholate) and amphoteric detergent and nuclease(3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate(CHAPS), deoxyribonuclease I, and ribonuclease A). All cellular components were successfully removed from the median and sural nerves by amphoteric detergent and nuclease. Not all cellular components were removed from the median nerve by nonionic and anionic detergent. Both median and sural nerves treated with amphoteric detergent and nuclease maintained a completely intact extracellular matrix. Treatment with nonionic and anionic detergent decreased collagen content in both median and sural nerves, while the amphoteric detergent and nuclease treatment did not reduce collagen content. In addition, a contact cytotoxicity assay revealed that the nerves decellularized by amphoteric detergent and nuclease was biocompatible. Strength failure testing demonstrated that the biomechanical properties of nerves decellularized with amphoteric detergent and nuclease were comparable to those of fresh controls. Decellularization with amphoteric detergent and nuclease better remove cellular components and better preserve extracellular matrix than decellularization with nonionic and anionic detergents, even in large-diameter human peripheral nerves. In Korea, cadaveric studies are not yet l

关键词： median nerve sural nerve nuclease detergent human decellularized nerve graft

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Observational Study of Surface Wind along a Sloping Surface over Mountainous Terrain during Winter

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Advances in Atmospheric Sciences 2018年第3期35卷 276-284页

作者： young-Hee LEE Gyuwon LEE Sangwon joo Kwang-Deuk AHN Department of Astronomy and Atmospheric Sciences Kyungpook National University Numerical Data Application Division Numerical Modeling Center

The 2018 Winter Olympic and Paralympic Games will be held in Pyeongchang, Korea, during February and March. We examined the near surface winds and wind gusts along the sloping surface at two outdoor venues in Pyeongchang during February and March using surface wind data. The outdoor venues are located in a complex, mountainous terrain, and hence the near-surface winds form intricate patterns due to the interplay between large-scale and locally forced winds. During February and March, the dominant wind at the ridge level is westerly; however, a significant wind direction change is ob- served along the sloping surface at the venues. The winds on the sloping surface are also influenced by thermal forcing, showing increased upslope flow during daytime. When neutral air flows over the hill, the windward and leeward flows show a significantly different behavior. A higher correlation of the wind speed between upper- and lower-level stations is shown in the windward region compared with the leeward region. The strong synoptic wind, small width of the ridge, and steep leeward ridge slope angle provide favorable conditions for flow separation at the leeward toot of the ridge. The gust factor increases with decreasing surface elevation and is larger during daytime than nighttime. A significantly large gust factor is also observed in the leeward region.

关键词： flow separation gust factor leeward region sloping surface

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Malignant sweat gland tumor of breast arising in pre-existing benign tumor: A case report

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World Journal of Clinical Cases 2019年第19期7卷 3033-3038页

作者： Jin Kyung An Jeong joo Woo young Ok Hong Department of Radiology Nowon Eulji Medical CenterEulji UniversitySeoul 01830South Korea Department of Pathology Nowon Eulji Medical CenterEulji UniversitySeoul 01830South Korea

BACKGROUND Sweat glands belong to skin *** gland tumors are uncommon,especially when they occur as malignant tumors in the *** report a case of malignant sweat gland tumor of the breast,including imaging and pathological *** SUMMARY A 47-year-old woman visited our hospital with a non-tender palpable lesion in her left *** lesion had not shown changes for 10 ***,it recently increased in *** showed a well circumscribed cystic lesion with internal debris and fluid-fluid *** resonance imaging showed a well circumscribed oval mass with T1 hyper-intensity compared to muscle and T2 high signal *** was a small enhancing mural component in the inner wall of the *** tumor was *** pathologic result was a malignant transformation of benign sweat gland tumor such as *** lesion was treated with excision and radiation *** 1-year follow up,there was no local recurrence or metastasis in the *** In the case of a rapid growing cystic mass in the nipple and subareola,it is necessary to distinguish it from a malignant sweat gland tumor.

关键词： Sweat gland neoplasm Breast Ultrasonography Magnetic resonance imaging

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Deformation prediction of porcelain-enameled steels with strain history by press forming and high-temperature behavior of coating layer

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中国有色金属学会会刊：英文版 2012年第S3期22卷 838-844页

作者： young-Ki SON Chan-joo LEE Jung-Min LEE Byung-Min KIM School of Mechanical Engineering Pusan National University Dongnam Regional Division Korea Institute of Industrial Technology

Porcelain enamel coatings were widely applied for the protection of steel products because they offered high corrosion protection,resistance to heat and abrasion,high hardness,hygiene and ease of *** typical process to produce enameled steels is roughly divided into two stages:the first stage consists of a forming process to give the desired shape to a steel substrate,and the second stage consists of a firing process to bond enamel frits on the *** firing process requires a high temperature above 800 °C,which may lead to austenitic transformation and severe thermal deformation of the steel *** aim of this study is to develop a finite element analysis (FE analysis) technique to predict the mechanical and thermal deformations of the enameled steels during forming and any further enameling process,including *** FE analysis involves analyzing the strain history of the steel substrate,which comprises the stress and thickness distributions of the substrate and its deformed shape,and the high-temperature behavior of the enamel coating *** validity of the FE analysis is verified through the U-bending test and firing test with various numbers and positions of enamel coating layers on the *** results reveal that the FE analysis results agree well with the experimental results with 8% error.

关键词： porcelain enamel firing process finite element analysis enameled steel thermal deformation

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SEQUENCES OF POWERS OF TOEPLITZ OPERATORS ON THE BERGMAN SPACE

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Acta Mathematica Scientia 2021年第3期41卷 657-669页

作者： Yong CHEN Kei Ji IZUCHI Kou Hei IZUCHI young joo LEE Department of Mathematics Hangzhou Normal UniversityHangzhou 311121China Department of Mathematics Niigata UniversityNiigata 950-2181Japan Department of Mathematics Faculty of EducationYamaguchi UniversityYamaguchi 753-8511Japan Department of Mathematics Chonnam National UniversityGwangju 61186Korea

We consider Toeplitz operators Tu with symbol u on the Bergman space of the unit ball,and then study the convergences and summability for the sequences of powers of Toeplitz *** first charactreize analytic symbolsφfor which the sequence Tφ*kf or Tφkf converges to 0 or∞as k→∞in norm for every nonzero Bergman function ***,we characterize analytic symbolsφfor which the norm of such a sequence is summable or not *** also study the corresponding problems on an infinite direct sum of Bergman spaces as a generalization of our result.

关键词： Bergman space Toeplitz operator

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海陆过渡相与海相页岩气储层特征差异性分析——以南川地区龙潭组与龙马溪组为例

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海洋地质前沿 2024年第10期40卷 49-60页

作者：刘娜娜张培先夏威高全芳汪凯明周頔娜中国石油化工股份有限公司华东油气分公司南京210019

南川地区发育海陆过渡相、海相2种沉积类型的页岩层系,以龙马溪组为代表的海相页岩气实现了商业开发,而对以龙潭组为代表的海陆过渡相页岩气的认识程度较低。利用野外露头、钻井岩芯、薄片及氩离子抛光扫描电镜等实验数据和地层微电阻... 详细信息

南川地区发育海陆过渡相、海相2种沉积类型的页岩层系,以龙马溪组为代表的海相页岩气实现了商业开发,而对以龙潭组为代表的海陆过渡相页岩气的认识程度较低。利用野外露头、钻井岩芯、薄片及氩离子抛光扫描电镜等实验数据和地层微电阻率扫描成像(FMI)测井等资料,从沉积相、岩性组合、储集条件、矿物组分、可压性及含气性等方面,开展这2套页岩储层特征的差异性分析。结果表明,2套储层在以上方面都存在较大差异:①龙潭组岩性复杂,发育粉砂质页岩、炭质页岩、灰质页岩、灰岩及煤层,而龙马溪组主要以硅质页岩为主;②受岩性、有机质类型及热演化程度影响,龙潭组储集空间主要以微裂缝(粒缘缝和收缩缝)和无机孔为主,而龙马溪组主要以有机质孔和微裂缝为主;③龙潭组页岩黏土矿物含量高(47.6%),脆性矿物含量低(35.8%),杨氏模量低(32.3 GPa),泊松比高(0.3),塑性较强,可压性差于龙马溪组页岩;④龙潭组页岩含气量平均为2.2 m^(3)/t,吸附气占比54.5%,而龙马溪组页岩含气量平均为5.2 m^(3)/t,吸附气占比43.3%。通过2套页岩层系储层差异性分析,明确了龙潭组页岩储层具有岩性复杂、黏土矿物含量高、可压性差、吸附气占比高的特征。龙潭组谭一段页岩连续厚度大、含气量高、储集物性好,从整体性评价来看,是龙潭组的“甜点”段;但其黏土矿物含量也高,且地质“甜点”与工程“甜点”的耦合性较龙马溪组页岩差,建议优化压裂工艺,提高缝网改造体积和单井产量,实现勘探突破。

关键词：海陆过渡相海相龙潭组页岩气储层特征差异性

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nanodendrites of platinum-group metals for electrocatalytic applications

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nano Research 2018年第12期11卷 6111-6140页

作者： Nitin K.Chaudhari Jinwhan joo Hyuk-bu Kwon Byeongyoon Kim Ho young Kim Sang Hoon joo Kwangyeol Lee Department of Chemistry Korea UniversitySeou102841Republic of Korea Research Institute of natural Sciences (RINS) Korea UniversitySeou102841Republic of Korea School of Energy and Chemical Engineering Ulsan National Institute of Science and Technology (UNIST)Ulsan44919Republic of Korea

Developing highly efficient and durable catalysts for future electrochemical and energy applications is one of the main subjects of current studies in renewable energy generation. In the past several years, researchers have developed Pt-based alloy electrocatalyst nanomaterials that exhibit promising electrocatalytic properties for various electrochemical applications. The efficient structural and morphological control of Pt-based alloy materials plays a decisive role in achieving these enhanced electrocatalytic properties. The present review article emphasizes the recent progress and important developments in the synthesis and electrocatalytic applications of Pt-group-based nanodendrite materials. The following review will help the exploration and development of better catalysts for practical applications and aims to elucidate the nanodendrite structure of Pt-group metals.

关键词： nanodendrites platinum-group metals electrochemical and energy conversion nanostructure

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Association between sensitivity to thyroid hormones and non-highdensity lipoprotein cholesterol levels in patients with type 2 diabetes mellitus

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World Journal of Diabetes 2024年第10期15卷 2081-2092页

作者： Xiao-Ye Duan Jun-Ling Fu Li-na Sun Zhi-Jing Mu Shuang-Ling Xiu Department of Endocrinology Beijing Institute of GeriatricsXuanwu HospitalCapital Medical UniversityBeijing 100053China

BACKGROUND Dyslipidemia and type 2 diabetes mellitus(T2DM)are chronic conditions with substantial public health *** management of lipid metabolism in patients with T2DM is ***,there has been insufficient attention given to the relationship between thyroid hormone sensitivity and dyslipidemia in the T2DM population,particularly concerning non-high-density lipoprotein cholesterol(non-HDL-C).AIM To clarify the association between thyroid hormone sensitivity and dyslipidemia in patients with *** In this cross-sectional study,thyroid hormone sensitivity indices,the thyroid feedback quantile-based index(TFQI),the thyroid-stimulating hormone index(TSHI),the thyrotrophic T4 resistance index(TT4RI),and the free triiodothyronine(FT3)/free thyroxine(FT4)ratio were *** regression analysis was performed to determine the associations between those composite indices and non-HDL-C *** forest variable importance and Shapley Additive Explanations(SHAP)summary plots were used to identify the strength and direction of the association between hyper-non-HDL-C and its major *** Among the 994 participants,389(39.13%)had high non-HDL-C *** regression analysis revealed that the risk of hyper-non-HDL-C was positively correlated with the TFQI(OR:1.584;95%CI:1.088-2.304;P=0.016),TSHI(OR:1.238;95%CI:1.034-1.482;P=0.02),and TT4RI(OR:1.075;95%CI:1.006-1.149;P=0.032)but was not significantly correlated with the FT3/FT4 *** relationships between composite indices of the thyroid system and non-HDL-C levels differed according to *** increased risk of hyper-non-HDL-C was associated with elevated TSHI levels in men(OR:1.331;95%CI:1.003-1.766;P=0.048)but elevated TFQI levels in women(OR:2.337;95%CI:1.4-3.901;P=0.001).Among the analyzed variables,the average SHAP values were highest for TSHI,followed by *** Impaired sensitivity to thyroid hormones was associated with high non-HDL-C levels in

关键词： Non-high-density lipoprotein cholesterol Sensitivity to thyroid hormones Type 2 diabetes mellitus Thyroid feedback quantile-based index Free triiodothyronine/free thyroxine ratio

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Functional photonic structures for external interaction with flexible/ wearable devices

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nano Research 2021年第9期14卷 2904-2918页

作者： young Jin Yoo Se-Yeon Heo Yeong Jae Kim joo Hwan Ko Zafrin Ferdous Mira young Min Song School of Electrical Engineering and Computer Science Gwangju Institute of Science and Technology(GIST)123 Cheomdangwagi-roBukguGwangju 61005Republic of Korea Korea Institute of Ceramic Engineering&Technology Ceramics Test-Bed Center3321 Gyeongchung-daeroSindun-myeonIcheon-si Gyeonggi-do 17303Republic of Korea Anti-Viral Research Center Gwangju Institute of Science and Technology(GIST)123 Cheomdangwagi-roBukguGwangju 61005Republic of Korea AI Graduate School Gwangju Institute of Science and Technology(GIST)123 Cheomdangwagi-roBukguGwangju 61005Republic of Korea

In addition to vital functions,more subsidiary functions are being expected from wearable *** wearable technology thus far has achieved the ability to maintain homeostasis by continuously monitoring physiological *** quality of life improves if,through further developments of wearable devices to detect,announce,and even control unperceptive or noxious signals from the *** materials based on photonic engineering can fulfil the abovementioned *** to the flexibility and zero-power operation of such materials,they can be applied to conventional wearables without affecting existing *** achievements to freely tailoring a broad range of electromagnetic waves have encouraged the development of wearable systems for independent recognition/manipulation of light,pollution,chemicals,viruses and ***,the role that photonic engineering on a flexible platform plays in detecting or reacting to environmental changes is reviewed in terms of material selection,structural design,and regulation mechanisms from the ultraviolet to infrared spectral ***,issues emerging with the evolution of the wearable technology,such as Joule heating,battery durability,and user privacy,and the potential solution strategies are *** article provides a systematic review of current progress in wearable devices based on photonic structures as well as an overview of possible ubiquitous advances and their applications,providing diachronic perspectives and future outlook on the rapidly growing research field of wearable technology.

关键词： photonic structure wearable device health care device colorimetric sensor radiative cooling infrared camouflage

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Improving thermal efficiency and stability of laser welding process for magnesium alloy by combining power modulation and subatmospheric pressure environment

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Journal of Magnesium and Alloys 2022年第10期10卷 2788-2800页

作者： Jie Ning Suck-joo na Lin-Jie Zhang Xiang Wang Jian Long Won-Ik Cho State Key Laboratory for Mechanical Behavior of Materials Xi’an Jiaotong UniversityXi’an 710049China BIAS-Bremer Institut für angewandte Strahltechnik GmbH Klagenfurter Straße 528359 BremenGermany

The laser welding(LW)process of highly reflective materials presents low thermal efficiency and poor *** solve the problem,the effects of subatmospheric environment on LW process,technological parameters in subatmospheric environment on weld formation and welding with sinusoidal modulation of laser power on the stability of LW process in subatmospheric environment were *** AZ31magnesium(Mg)alloy was used as the test *** test result revealed that the weld penetration in subatmospheric environment can increase by more than ten times compared with that under normal *** the keyhole depth greatly rises,significantly periodic local bulge is observed on the backwall surface of the keyhole and the position of the bulge shifts along the direction of the keyhole ***,the hump-shaped surface morphology of the welded seam is formed;moreover,the weld width in local zones in the lower part of the welded seam remarkably *** LW in subatmospheric environment,the weld penetration can be further greatly increased through power ***,power modulation can inhibit the occurrence of bulges in local zones on the backwall of the keyhole during LW in subatmospheric environment,thus further curbing the significant growth of the weld widths of hump-shaped welding beads and local zones in the lower part of welded ***,the mechanism of synchronously improving the thermal efficiency and stability of LW process of highly reflective materials through power modulation in subatmospheric environment was *** was conducted according to theoretical analysis of recoil pressure and observation results of dynamic behaviors of laser induced plasma clouds and keyholes in the molten pool through high speed photography.

关键词： Laser welding Subatmospheric environment Power modulation Highly reflective materials Thermal efficiency Stability

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