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Improving thermal efficiency and stability of laser welding process for magnesium alloy by combining power modulation and subatmospheric pressure environment

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Journal of Magnesium and Alloys 2022年第10期10卷 2788-2800页

作者： Jie Ning Suck-joo Na Lin-Jie Zhang Xiang Wang Jian Long Won-Ik cho State Key Laboratory for Mechanical Behavior of Materials Xi’an Jiaotong UniversityXi’an 710049China BIAS-Bremer Institut für angewandte Strahltechnik GmbH Klagenfurter Straße 528359 BremenGermany

The laser welding(LW)process of highly reflective materials presents low thermal efficiency and poor *** solve the problem,the effects of subatmospheric environment on LW process,technological parameters in subatmospheric environment on weld formation and welding with sinusoidal modulation of laser power on the stability of LW process in subatmospheric environment were *** AZ31magnesium(Mg)alloy was used as the test *** test result revealed that the weld penetration in subatmospheric environment can increase by more than ten times compared with that under normal *** the keyhole depth greatly rises,significantly periodic local bulge is observed on the backwall surface of the keyhole and the position of the bulge shifts along the direction of the keyhole ***,the hump-shaped surface morphology of the welded seam is formed;moreover,the weld width in local zones in the lower part of the welded seam remarkably *** LW in subatmospheric environment,the weld penetration can be further greatly increased through power ***,power modulation can inhibit the occurrence of bulges in local zones on the backwall of the keyhole during LW in subatmospheric environment,thus further curbing the significant growth of the weld widths of hump-shaped welding beads and local zones in the lower part of welded ***,the mechanism of synchronously improving the thermal efficiency and stability of LW process of highly reflective materials through power modulation in subatmospheric environment was *** was conducted according to theoretical analysis of recoil pressure and observation results of dynamic behaviors of laser induced plasma clouds and keyholes in the molten pool through high speed photography.

关键词： Laser welding Subatmospheric environment Power modulation Highly reflective materials Thermal efficiency Stability

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A case of hypereosinophilic syndrome presenting with intractable gastric ulcers

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World Journal of Gastroenterology 2009年第48期15卷 6129-6133页

作者： Tae young Park Chang Hwan choi Suh Yoon Yang InSoo Oh In-Do Song Hyun Woong Lee Hyung joon Kim Jae Hyuk Do Sae Kyung Chang Ah Ra cho young joo Cha Department of Internal Medicine Chung-Ang University College of Medicine Department of Laboratory Medicine Chung-Ang University College of Medicine

We report a rare case of hypereosinophilic syndrome （HES） presenting with intractable gastric ulcers. A 71-year-old man was admitted with epigastric pain. Initial endoscopic findings revealed multiple, active gastric ulcers in the gastric antrum. He underwent Helicobacterpylori （Hpylon） eradication therapy followed by proton pump inhibitor （PPI） therapy. However, follow- up endoscopy at 4, 6, 10 and 14 mo revealed persistent multiple gastric ulcers without significant improvement. The proportion of his eosinophil count increased to 43% （total count： 7903/mm3）. Abdominal-pelvic and chest computed tomography scans showed multiple small nodules in the liver and both lungs. The endoscopic biopsy specimen taken from the gastric antrum revealed prominent eosinophilic infiltration, and the liver biopsy specimen also showed eosinophilic infiltration in the portal tract and sinusoid. A bone marrow biopsy disclosed eosinophilic hyperplasia as well as increased cellularity of 70%. The patient was finally diagnosed with HES involving the stomach, liver, lung, and bone marrow. When gastric ulcers do not improve despite H pylon eradication and prolonged PPI therapy, infiltrative gastric disorders such as HES should be considered.

关键词： Gastric ulcer Hypereosinophilic syndrome

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Influence of potassium pyrophosphate in electrolyte on coated layer of AZ91 Mg alloy formed by plasma electrolytic oxidation

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中国有色金属学会会刊：英文版 2009年第4期19卷 824-828页

作者： Jin-young cho Duck-young HWANG Dong-H eon LEE Bongyoung YOO Dong-Hyuk SHIN Department of Metallurgy and Materials Scienc e Hanyang University

The effect of potassium pyrophosphate in the electrolyte on plasma electrolytic oxidation(PEO) process for AZ91 Mg alloy was *** morphologies and chemical compositions of the coating layer on the AZ91 Mg alloy were evaluated and corrosion resistance was also estimated by potentiodynamic polarization *** coating layer on AZ91 Mg alloy coated from the Bath 2 containing 0.03 mol/L of potassium pyrophosphate for 360 s exhibited considerably dense structure and contained 11%-18%(mass fraction) of *** higher content of phosphorous of coating layer coated from Bath 2 could be detected at the bottom of oxide layer,which strongly implied that the phosphorous ion might be concentrated at the barrier *** potential of coating layer of AZ91 Mg alloy increased and corrosion current density decreased with increasing the concentration of potassium *** polarization resistance(Rp) of coating layer of AZ91 Mg alloy coated from Bath 2 was 4.65×107 Ω/cm2,which was higher than that(Rp=3.56×104 Ω/cm2) of the sample coated from electrolyte without potassium *** coating layer coated from Bath 2 containing 0.03 mol/L potassium pyrophosphate exhibited the best corrosion resistance.

关键词： AZ91镁合金合金涂层焦磷酸钾电解氧化等离子体电解质腐蚀电流密度耐腐蚀性

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Pancreatic tuberculosis masquerading as pancreatic serous cystadenoma

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World Journal of Gastroenterology 2009年第8期15卷 1010-1013页

作者： Seung Goun Hong Jae Seon Kim Moon Kyung joo Kwang Gyun Lee Key Hyeon Kim cho Rong Oh Jong-Jae Park young-Tae Bak Department of Internal Medicine Korea University College of Medicine Seoul South Korea

Solitary pancreatic involvement of tuberculosis is rare, especially in an immunocompetent individual, and it may be misdiagnosed as pancreatic cystic neoplasms. Pancreatic cystic neoplasms are being identified in increasing numbers, probably because of the frequent use of radiology and advances in endoscopic techniques. However, they are composed of a variety of neoplasms with a wide range of malignant potential, and it is often difficult to differentiate pancreatic tuberculosis mimicking cystic neoplasms from benign or malignant pancreatic cystic neoplasms. Non-surgical diagnosis of pancreatic tuberculosis is inconclusive and continues to be a challenge in many cases. If so, then laparotomy should be employed to establish the diagnosis. Therefore, pancreatic tuberculosis should be kept in mind during the differential diagnosis of solitary cystic masses in the pancreas. We report a patient who had solitary pancreatic tuberculosis masquerading as pancreatic serous cystadenoma.

关键词： Tuberculosis Pancreas Cystadenoma Serous neoplasm

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Effect of two different doses of intravitreal bevacizumab with temporal retina-sparing laser photocoagulation for retinopathy of prematurity

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International Journal of Ophthalmology(English edition) 2018年第1期11卷 166-169页

作者： A young choi Hochan cho Yu Cheol Kim Department of Ophthalmology Keimyung University School of Medicine Dongsan Medical Center Department of Internal Medicine Keimyung University School of Medicine Dongsan Medical Center

This study aims to compare the efficacy and safety between two different doses of intravitreal bevacizumab（IVB） injection with temporal retina-sparing laser（TRSL） photocoagulation for retinopathy of prematurity（ROP）. We retrospectively evaluated 22 eyes of ROP infants who underwent IVB combined with partial TRSL for stage 3＋ zone I or posterior zone II ROP. Laser photocoagulation was applied on the avascular retina, sparing two-discdiameter width temporal avascular area anterior to ridge. A half dose（0.625 mg） or minimal dose（0.25 mg） of IVB was conducted. Four eyes in minimal dose group were retreated with IVB and laser photocoagulation on the spared retina. Of those 4 retreated eyes, three developed preretinal hemorrhage around the ridge after the first treatment, resulting in fibrotic macular dragging. A half dose of IVB may be more effective than a minimal dose with partial TRSL for ROP. Preretinal hemorrhage may be a harbinger of poor prognosis.

关键词： bevacizumab laser photocoagulation retinopathy of prematurity

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Association of chronic viral hepatitis B with insulin resistance

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World Journal of Gastroenterology 2012年第42期18卷 6120-6126页

作者： Jeong Gyu Lee Sangyeoup Lee Yun Jin Kim Byung Mann cho joo Sung Park Hyung Hoi Kim JaeHun Cheong Dong Wook Jeong Yu Hyun Lee young Hye cho Mi Jin Bae Eun Jung choi Department of Family Medicine Pusan National University School of MedicineBeomeo-ri Mulgeum-eupYangsan 626-770South Korea Department of Family Medicine Medical Research InstitutePusan National University HospitalBusan 602-739South Korea Medical Education Unit Pusan National University School of MedicineBeomeo-ri Mulgeum-eupYangsan 626-770South Korea Family Medicine Clinic Yangsan Pusan National University HospitalBeomeo-ri Mulgeum-eupYangsan 626-770South Korea Department of Preventive Medicine and Occupational Medicine Pusan National University School of MedicineBeomeo-ri Mulgeum-eupYangsan 626-770South Korea Department of Family Medicine Dong-A University Medical CenterBusan 602-715South Korea Department of Laboratory Medicine Biomedical Informatics UnitPusan National University School of MedicineBeomeo-ri Mulgeum-eupYangsan 626-770South Korea Department of Molecular Biology College of Natural SciencesPusan National UniversityBusan 602-739South Korea

AIM:To investigate the relationship between chronic viral hepatitis B(CVHB) and insulin resistance(IR) in Korean ***:A total of 7880 adults(3851 men,4029 women) who underwent a comprehensive medical examination were enrolled in this *** diagnosed with either diabetes mellitus,or any other disorder that could influence their insulin sensitivity,were ***,metabolic risk factors,hepatitis B surface antigen,hepatitis B surface antibody,hepatitis B core antibody,fasting plasma glucose and insulin were measured for all *** model assessment(HOMA),quantitative insulin check index(QUICKI),and Mf fm index were used for determining insulin *** participant was categorized into a negative,recovery,or CVHB *** compare variables between groups,a t-test and/or one-way analysis of variance were *** correlation coefficients were computed to present the association between insulin resistance and other *** logistic regression analysis was used to assess the independent association between CVHB and ***:The mean age of men and women were 48.9 and 48.6 years,*** in the CVHB group had significantly higher waist circumference [(86.0 ± 7.7 cm vs 87.3 ± 7.8 cm,P = 0.004 in men),(78.3 ± 8.6 cm vs 80.5 ± 8.5 cm,P cholesterol(r = 0.134,P < 0.00

关键词： Hepatitis B Insulin resistance Diabetes mellitus type 2 Metabolic syndrome

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Syndrome Pattern and Its Application in Parallel Randomized Controlled Trials

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Chinese Journal of Integrative Medicine 2013年第3期19卷 163-171页

作者： Byung-Cheul Shin Sina Kim young-Hun cho Division of Clinical Medicine School of Korean MedicinePusan National University Department of Korean Medicine School of Korean MedicinePusan National University Department of Korean Medical Science School of Korean MedicinePusan National University

Syndrome pattern （SP） is a core concept of Chinese medicine （CM） and is used to diagnose and treat patients based on an overall analysis of symptoms and signs. This study aimed to systematically review randomized controlled trials （RCTs） using the SP concept and to demonstrate how the SP concept could be applied to the study design of parallel RCTs, considering a gold standard of clinical research. After conducting a brief systematic review by way of a PubMed search, we analyzed how the SP concept was applied to the design of RCT in a CM herbal medicine trial. We then formulated possible research questions, applied the SP concept to answer the research questions, and suggested possible RCT designs to be used for conducting future trials. Fourteen RCTs were included in our systematic review, and three key points of the SP concept were formulated for the design of parallel RCTs： the time point of SP diagnosis between before and after randomization; the relationship between the international classification of diseases （ICD） and SP for the inclusion of target population; and the proper diagnostic method of SP. In this study, we formulated three possible research questions and then suggested perspectives for five possible RCT models arrived at using SP concepts. Future trials applying SP concept to RCTs should overcome the shortcomings of past SP trials, moving CM forward from experience-based to evidence-based medicine.

关键词： syndrome pattern randomized controlled trial traditional Chinese medicine evidence-basedmedicine integrative medicine

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Celecoxib attenuates 5-fluorouracil-induced apoptosis in HCT-15 and HT-29 human colon cancer cells

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World Journal of Gastroenterology 2007年第13期13卷 1947-1952页

作者： Yun Jeong Lim Jong Chul Rhee young Mee Bae Wan joo Chun Department of Internal Medicine Dongguk University International Hospital Dongguk University College of Medicine Goyang Korea Division of Gastroenterology Department of Internal Medicine Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea Department of Parasitology Seoul National University College of Medicine Seoul Korea Department of Pharmacology Kangwon National University College of Medicine Chuncheon Korea

AIM： To investigate the combined chemotherapeutic effects of celecoxib when used with 5-FU in vitro. METHODS： Two human colon cancer cell lines （HCT-15 and HT-29） were treated with 5-FU and celecoxib, alone and in combination. The effects of each drug were evaluated using the MTT （3-（4, 5-dimethylthiazol-2-yl）-2, 5-diphenyltetrazolium bromide） assay, flow cytometry, and western blotting. RESULTS： 5-FU and celecoxib showed a dosedependent cytotoxic effect. When treated with 10-3 mol/L 5-FU （IC50） and celecoxib with its concentration ranging from 10.8 mol/L to 10.4 mol/L of celecoxib, cells showed reduced cytotoxic effect than 5-FU （10.3 mol/L） alone. Flow cytometry showed that celecoxib attenuated 5-FU induced accumulation of cells at subG1 phase. Western blot analyses for caspase-3 and poly （ADP-ribose） polymerase （PARP） cleavage showed that celecoxib attenuated 5-FU induced apoptosis. Western blot analyses for cell cycle molecules showed that G2/M arrest might be possible cause of 5-FU induced apoptosis and celecoxib attenuated 5-FU induced apoptosis via blocking of cell cycle progression to the G2/M phase, causing an accumulation of cells at the GI/S phase. CONCLUSION： We found that celecoxib attenuated cytotoxic effect of 5-FU. Celecoxib might act via inhibition of cell cycle progression, thus preventing apoptosis induced by 5-FU.

关键词： Antagonism Celecoxib Colorectal neoplasms Fluorouracil

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Nationwide Trends in the Prevalence of Cigarette and E-cigarette Smoking among Korean Adults between 2014-2021:A Representative Serial Study of 1.2 Million Individuals

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Biomedical and Environmental Sciences 2023年第10期36卷 996-998页

作者： Minji Kim Wonyoung cho Jinseok Lee Yong Sung choi Seung Geun Yeo young joo Lee Sang Youl Rhee Chanyang Min Dong Keon Yon Center for Digital Health Medical Science Research InstituteKyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Department of Regulatory Science Kyung Hee UniversitySeoulSouth Korea Department of Biomedical Engineering Kyung Hee UniversityYonginSouth Korea Department of Pediatrics Kyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Department of Otolaryngology-Head&Neck Surgery Kyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Department of Obstetrics and Gynecology Kyung Hee University College of MedicineSeoulSouth Korea Department of Endocrinology and Metabolism Kyung Hee University College of MedicineSeoulKorea

Both cigarette and e-cigarette use cause respiratory tract damage and related health outcomes,and potentially increase the risk of coronavirus disease 2019(COVID-19)-related symptoms[1].Since the COVID-19 pandemic,loc... 详细信息

关键词： respiratory damage legal

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Flow characteristics of aluminum coated boron steel in hot press forming

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中国有色金属学会会刊：英文版 2009年第4期19卷 913-916页

作者： Jeong-Hwan JANG Jae-Ho LEE Bye ong-Don joo young-Hoon MOON School of Mechanical Engineering Pusan National University

The flow characteristics of aluminum coated boron steel in hot press forming were ***,the effects of aluminum coated layer on press forming were analyzed during deep *** results show that aluminum coated boron steel exhibits a high sensitivity on temperature and strain *** coating layer appears in surface flaking in a temperature range of 700-800 ℃,but smooth surface is formed above 900 ℃.

关键词：热压成型流动特性铝涂层硼钢表面剥落温度范围冲压成形高灵敏度

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