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The ALMA-QUARKS Survey.Ⅰ.Survey Description and Data Reduction

Research in Astronomy and Astrophysics 2024年第2期24卷 104-124页

作者：刘训川 Tie Liu Lei Zhu Guido Garay Hong-Li Liu Paul Goldsmith Neal Evans Kee-Tae kim Sheng-Yuan Liu Fengwei Xu Xing Lu Anandmayee Tej Xiaofeng Mai Leonardo Bronfman Shanghuo Li Diego Mardones Amelia Stutz Ken'ichi Tatematsu Ke Wang Qizhou Zhang Sheng-Li Qin Jianwen Zhou Qiuyi Luo Siju Zhang Yu Cheng Jinhua He Qilao Gu Ziyang Li Zhenying Zhang Suinan Zhang Anindya Saha Lokesh Dewangan Patricio Sanhueza Zhiqiang Shen Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China Chinese Academy of Sciences South America Center for Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Departamento de Astronomía Universidad de ChileLas Condes7591245 SantiagoChile School of Physics and Astronomy Yunnan UniversityKunming 650091China Jet Propulsion Laboratory California Institute of Technology4800 Oak Grove DrivePasadena CA 91109USA Department of Astronomy The University of Texas at AustinTX 78712-1205USA Korea Astronomy and Space Science Institute 776 Daedeokdae-roYuseong-guDaejeon 34055Republic of Korea Institute of Astronomy and Astrophysics Academia SinicaRoosevelt RoadTaipei 10617China Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China Department of Astronomy School of PhysicsPeking UniversityBeijing 100871China Indian Institute of Space Science and Technology Thiruvananthapuram 695547KeralaIndia Max Planck Institute for Astronomy Königstuhl 17D-69117 HeidelbergGermany Departamento de Astronomía Universidad de ConcepciónCasilla 160-CConcepciónChile Nobeyama Radio Observatory National Astronomical Observatory of JapanNational Institutes of Natural Sciences462-2 NobeyamaMinamimakiMinamisakuNagano 384-1305Japan Center for Astrophysics∣Harvard&Smithsonian 60 Garden StreetCambridgeMA 02138USA Max-Planck-Institut für Radioastronomie Auf dem Hügel 69D-53125 BonnGermany School of Astronomy and Space Sciences University of Chinese Academy of SciencesBeijing 100049China National Astronomical Observatory of Japan 2-21-1 OsawaMitakaTokyo181-8588Japan Yunnan Observatories Chinese Academy of SciencesKunming 650216China Physical Research Laboratory NavrangpuraAhmedabad-380009India Astronomical Science Program The Graduate University for Advanced StudiesSOKENDAI2-21-1 OsawaMitakaTokyo 181-8588Japan University of Science and Technology Korea(UST)217 Gajeong-roYuseong-guDaejeon 34113Republic o

This paper presents an overview of the QUARKS survey,which stands for Querying Underlying mechanisms of massive star formation with ALMA-Resolved gas Kinematics and Structures."The QUARKS survey is observing139 massive clumps covered by 156 pointings at Atacama Large Millimeter/submillimeter Array(ALMA)Band 6(λ~1.3 mm).In conjunction with data obtained from the ALMA-ATOMS survey at Band 3(λ~3 mm),QUARKS aims to carry out an unbiased statistical investigation of massive star formation process within protoclusters down to a scale of 1000 *** overview paper describes the observations and data reduction of the QUARKS survey,and gives a first look at an exemplar source,the mini-starburst Sgr B2(M).The wide-b and width(7.5 GHz)and high-angular-resolution(~0."3)observations of the QUARKS survey allow for the resolution of much more compact cores than those could be done by the ATOMS survey,and to detect previously unrevealed fainter filamentary *** spectral windows cover transitions of species including CO,SO,N_(2)D^(+),SiO,H_(30)α,H_(2)CO,CH_(3)CN,and many other complex organic molecules,tracing gas components with different temperatures and spatial *** aims to deepen our understanding of several scientific topics of massive star formation,such as the mass transport within protoclusters by(hub-)filamentary structures,the existence of massive starless cores,the physical and chemical properties of dense cores within protoclusters,and the feedback from already formed high-mass young protostars.

关键词： stars formation-stars kinematics and dynamics-ISM clouds-ISM molecules

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Research Priorities for Addressing Gender Based Violence in the WHO Africa Region

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Advances in Reproductive Sciences 2021年第1期9卷 50-59页

作者： Leopold Ouedraogo Triphonie Nkurunziza Assumpta Muriithi Bigirimana Françoise Chilanga Asmani Hayfa Elamin Souleymane Zan Mihretu Belete Gbenou Dina Dadji Kwami Theopista Kabuteni John kim Caron Rahn Ali Moazzam Tolu Lemi Blami Dao Issiaka Sombie Okech Mollent Reproductive Maternal Health and Ageing WHO Regional Office for Africa Brazzaville Congo Department of Reproductive Health and Research World Health Organization Geneva Switzerland JHPIEGO Ouagadougou Burkina Faso West Africa Health Organization Ouagadougou Burkina Faso Peak Moments Global HR Solutions Nairobi Kenya

Background: There is an increasing emphasis on conducting research to identify gender based violence issues to enable development of appropriate programs and interventions. However, these efforts are mixed in quality and often raise ethical questions. The increased pressure on policy makers to move to a more evidence-based approach in addressing gender based issues creates the need for this research prioritization activity. Inadequate evaluative evidence in this area poses a challenge in the planning for responsive interventions especially in resource limited settings. The purpose of this paper is to present gender based violence research priority areas for the WHO Africa Region. Methods: We utilized a modified version of the Child Health and Nutrition Research Initiative approach to reach consensus on research priorities on the thematic area of gender based violence. In three phases, we first conducted an online survey with sexual and reproductive health and rights experts in academia, ministries of health, non-governmental organizations and other health actors with a wide range of experiences. These questions were consolidated by three experts from World Health Organization headquarters into themes. Secondly, experts were invited in a meeting in Cape Town South Africa to analyze and generate relevant areas of research based on the themes. Finally, a smaller group of experts prioritized research areas based on agreed criteria. Results: A list of 10 priority research questions for addressing gender based violence were scored and ranked. Four priority research questions scored 30 points out of the possible 30 points and were thus ranked as the highest priority. These included questions that “engage young adolescents in behavioral interventions to influence gender roles”, “determinants of gender based violence analysis”, “both long and short term complications of gender based violence on survivors” and “assessment of

关键词： Gender-Based Violence Gender Human Rights Sexual and Reproductive Health Violence

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超高分子量聚丙烯冻胶纤维的力学性能研究

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材料工程 2008年第10期36卷 339-341页

作者：司小娟陈建军程丹丹 Jeong Cheol kima 王依民东华大学材料科学与工程学院上海201620 韩国工业研究院韩国纤维材料改性国家重点实验室上海201620

采用冻胶纺丝法制备超高分子量聚丙烯纤维(UHMWPP),并在不同的拉伸温度下对其进行拉伸。研究了在不同拉伸倍率下,拉伸温度对UHMWPP纤维力学性能的影响。结果表面:UHMWPP纤维在室温低拉伸倍率下表现为结晶高聚物的拉伸行为,高温时则为硬... 详细信息

采用冻胶纺丝法制备超高分子量聚丙烯纤维(UHMWPP),并在不同的拉伸温度下对其进行拉伸。研究了在不同拉伸倍率下,拉伸温度对UHMWPP纤维力学性能的影响。结果表面:UHMWPP纤维在室温低拉伸倍率下表现为结晶高聚物的拉伸行为,高温时则为硬弹性材料的拉伸行为。纤维的断裂强度与杨氏模量主要由拉伸倍率决定,断裂伸长率则由拉伸倍率和拉伸温度决定。

关键词：冻胶纺超高分子量聚丙烯纤维力学性能

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血管内皮细胞生长因子和血管发生素-1及其受体在斑马鱼早期胚胎发育过程中的表达

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时珍国医国药 2006年第6期17卷 912-913页

作者：柳明洙张学武高圭永金善姬延边大学基础医学院韩国科学技术大学韩国全北大学校医科大学南开大学吉林延吉133000 韩国大田305-701 韩国全州560-180 天津300071

目的探讨血管内皮细胞生长因子和血管发生素-1及其受体在斑马鱼早期胚胎发育过程中的表达,为构建药物筛选的在体模型提供依据。方法采用多聚酶链式反应,扩增了长约280bp的斑马鱼血管发生素-1 cDNA部分序列,作为探针,以原位杂交法测定了... 详细信息

目的探讨血管内皮细胞生长因子和血管发生素-1及其受体在斑马鱼早期胚胎发育过程中的表达,为构建药物筛选的在体模型提供依据。方法采用多聚酶链式反应,扩增了长约280bp的斑马鱼血管发生素-1 cDNA部分序列,作为探针,以原位杂交法测定了血管内皮细胞生长因子和血管发生素-1及其相应受体flk-1和Tie-2的表达。结果从受精卵胚胎发育第12小时可见血管内皮细胞生长因子和血管发生素-1及其相应受体flk-1和Tie-2的表达;在受精卵胚胎发育的第16小时,血管内皮细胞生长因子和血管发生素-1主要在头部和尾部胚芽表达;第24小时在眼球、视窝、中脑、后脑的腹前侧和肌节中表达,Tie2和F lk-1主要在肌间背部动脉血管、躯干新生血管芽和轴向静脉中表达。结论血管内皮细胞生长因子和血管发生素-1及其受体在斑马鱼胚胎发育早期的血管发生过程中可能相互作用,并协调血管发生过程。斑马鱼是研究胚胎发育早期微血管发生和血管发生的极佳动物模型,可用于促血管发生或抑制血管发生药物筛选。

关键词：斑马鱼血管发生素-1 血管内皮生长因子受体

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星形胶质细胞源性腺苷激发腹外侧视前核中的促睡眠神经元:星形胶质细胞-神经元相互作用对睡眠的调节

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神经损伤与功能重建 2022年第6期17卷 372-372页

作者： In-Sun Choi Jae-Hong kim Ji-young Jeong Maan-Gee Lee Kyoungho Suk Il-Sung Jang 杜一星(编译) Department of Pharmacology School of DentistryKyungpook National UniversityDaeguSouth Korea Department of Pharmacology School of MedicineKyungpook National UniversityDaeguSouth Korea Brain Science&Engineering Institute Kyungpook National UniversityDaeguSouth Korea 不详

尽管已知来自星形胶质细胞的ATP和/或腺苷可调节睡眠,但ATP和腺苷促眠作用的确切机制仍不清楚。我们在参与睡眠促进的重要脑核腹外侧视前核(VLPO)内的星形胶质细胞中选择性表达光敏离子通道视紫红质通道2(ChR2)。然后,我们用全细胞膜片... 详细信息

尽管已知来自星形胶质细胞的ATP和/或腺苷可调节睡眠,但ATP和腺苷促眠作用的确切机制仍不清楚。我们在参与睡眠促进的重要脑核腹外侧视前核(VLPO)内的星形胶质细胞中选择性表达光敏离子通道视紫红质通道2(ChR2)。然后,我们用全细胞膜片钳记录检查了光刺激星形细胞ChR2对VLPO两种不同功能类型的神经元兴奋性的影响:分别为促进睡眠的GABA能投射神经元和非促进睡眠的局部GABA能神经元。VLPO星形胶质细胞的光遗传学刺激在两种类型的VLPO神经元中表现出相反的结果:导致了非睡眠促进神经元的抑制和睡眠促进神经元的兴奋。通过阻断腺苷A1受体或组织非特异性碱性磷酸酶(TNAP)可减弱这些反应。相反,外源性腺苷降低了两个VLPO神经元群的兴奋性。此外,TNAP在甘丙肽阴性的VLPO神经元中表达,但在甘丙肽阳性促进睡眠的投射神经元中不表达。总之,这些结果表明星形胶质细胞源性的ATP在非睡眠促进神经元中通过TNAP转化为腺苷。腺苷进而降低了局部GABA能神经元的兴奋性,从而增加了促进睡眠的GABA能投射神经元的兴奋性。我们提出了一种涉及星形胶质细胞-神经元相互作用在睡眠调节中的新机制,其中来自星形胶质细胞的内源性腺苷激发促进睡眠的VLPO神经元,从而降低大脑中与唤醒相关区域的神经元兴奋性。

关键词：腺苷星形胶质细胞胶质递质光遗传学睡眠腹外侧视前核

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韩国原发性结肠淋巴瘤状况:一项KASID(韩国肠病研究协会)研究

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世界核心医学期刊文摘（胃肠病学分册） 2006年第4期2卷 10-11页

作者： kim Y.-H Lee J.H Yang S.K. J.C. Rhee 纪泛扑 Department of Medicine Samsung Medical Center 50 Irwon-Dong Kangnam-ku Seoul 135-710 South KoreaDr.

Although almost all primary colorectal lymphomas are of B-cell lineage in Western countries, primary colorectal T-cell lymphomas are not uncommon in the East. The aim of this study was to review the clinical characteristics and treatment outcomes of primary colorectal lymphomas, with special emphasis on the differences between T-cell and B-cell lymphomas. Ninety-five cases of primary colorectal lymphomas that satisfied Dawson‘s criteria were identified from the clinical databases of 13 university hospitals in Korea. The mean age at the time of presentation was 51.1 years and the male : female ratio was 64 ∶31. The clinical information, including endoscopic and histological characteristics, was retrospectively analyzed. Of the primary colorectal lymphomas, 78 cases (82.1%) were of B-lineage and 17 cases (17.9%) were of T-cell lineage. Patients with T-cell lymphomas presented at a younger age than patients with B-cell lymphomas (42.8 vs 52.9 years, respectively; P = 0.016). The most common presenting symptom was abdominal pain (87.1%) for B-cell lymphomas, whereas hematochezia or night fe ver was more common for T-cell lymphomas (52.9%and 35.3%, respectively). The most common endoscopic type was fungating mass (54.0%) for B-cell lymphomas and ulcerative/ ulcero-infiltrative lesions (80.0%) for T-cell lymphomas. Intussusception was more common in B-cell lymphomas than in T-cell lymphomas(30.8%vs 5.9%, respectively; P = 0.035), but perforation was more common in T-cell lymphomas than in B-cell lymphomas (23.5%vs 3.8%, respectively; P = 0.005). The prognosis was significantly worse for T-cell lymphomas than for B-cell lymphomas (P = 0.002). Primary colorectal T-cell lymphomas are characterized by multifocal ulcerative lesions in relatively young patients , a high rate of hematochezia, fever, or perforation, and a poor prognosis even for cases of localized disease.

关键词：结肠淋巴瘤 KASID 研究协会结肠直肠淋巴瘤患者淋巴瘤病组织学特征发病年龄病灶局限溃

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病毒性肝炎:乙型肝炎和丁型肝炎-临床(治疗、新化合物、耐药性) 一项在HBeAg阴性、慢性乙型肝炎(CHB)患者中比较磷丙替诺福韦(TAF)与富马酸替诺福韦二吡呋酯(TDF)的3期研究:96周时疗效和安全性结果

病毒性肝炎:乙型肝炎和丁型肝炎-临床(治疗、新化合物、耐药性) ...

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第九届全国疑难及重症肝病大会

作者： Maurizia Brunetto young Suk Lim Ed Gane Wai Kay Seto Marina Osipenko Sang Hoon Ahn Harry L.Janssen Akash Shukla Wan Long Chuang Huy Trinh Mustafa K.Celen John F.Flaherty Audrey H.Lau Anuj Gaggar Vithika Suri Neeru Bhardwaj Kyungpil kim G Mani Subramanian Calvin Pan Namiki Izumi Patrick Marcellin Henry Chan Maria Buti University Hospital of Pisa Asan Medical Centre Erasmus Medical Center

背景和目的:TAF是替诺福韦(TFV)的一种新型前体药,在血浆中比TDF更稳定,增强了TFV进入肝细胞的给药,且循环TFV水平降低。这项在HBeAg阴性患者中比较TAF与TDF的随机双盲研究显示,之前在48周时,在HBV DNA小于29IU/mL的患者比例方面,TAF的...

背景和目的:TAF是替诺福韦(TFV)的一种新型前体药,在血浆中比TDF更稳定,增强了TFV进入肝细胞的给药,且循环TFV水平降低。这项在HBeAg阴性患者中比较TAF与TDF的随机双盲研究显示,之前在48周时,在HBV DNA小于29IU/mL的患者比例方面,TAF的疗效并不劣于TDF,且骨骼和肾脏影响改善。本文摘展示了96周治疗后的结果。方法:425例患者被随机分配到接受TAF 25mg QD(n=285)或TDF 300mg QD(n=140),且治疗144

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AME证据系列001--转化医学协会:脓毒症诊断和早期识别的临床实践指南

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临床与病理杂志 2016年第10期36卷 1467-1476页

作者： Zhongheng Zhang Nathan J.Smischney Haibo Zhang Sven Van Poucke Panagiotis Tsirigotis Jordi Rello Patrick M.Honore Win Sen Kuan Juliet June Ray Jiancang Zhou You Shang Yuetian Yu Christian Jung Chiara Robba Fabio Silvio Taccone Pietro Caironi David Grimaldi Stefan Hofer George Dimopoulos Marc Leone Sang-Bum Hong Mabrouk Bahloul Laurent Argaud Won young kim Herbert D.Spapen Jose Rodolfo Rocco 张建成(译) 尚游(译) 钟鸣(校) Department of Emergency Medicine Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016 Department of Critical Care Medicine Jinhua Hospital of Zhejiang UniversityJinhua Zhejiang 321000 Department of Anesthesiology Mayo ClinicRochesterMNUSA Keenan Research Center for Biomedical Science of St.Michael's Hospital Departments of Anesthesia and PhysiologyInterdepartmental Division of Critical Care MedicineUniversity of TorontoTorontoONCanada Departments of Anesthesiology Critical CareEmergency Medicine and Pain TherapyZiekenhuis Oost-Limburgy GenkBelgium 2nd Department of Internal Medicine Attikcon University HospitalMedical SchoolNational and Kapodistrian University of AthensAthensGreece CIBERES Vall d'Hebron Institut of ResearchUniversitat Autonoma de BarcelonaSpain Universitair Ziekenhuis Brussely Vrije Universiteit Brussel Brussels BrusselsBelgium Emergency Medicine Department National University HospitalNational University Health SystemSingapore and the Department of SurgeryYong Loo Lin School of MedicineNational University of SingaporeSingapore DeWitt Daughtry Family Department of Surgery Jackson Memorial HospitalUniversity of Miami Leonard M.Miller School of MedicineMiamiFLUSA Department of Critical Care Medicine Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016 Department of Critical Care Medicine Union HospitalTongji Medical CollegueHuazhong University of Science and TechnologyWuhan 430022 Department of Critical Care Medicine Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200001 University Hospital Dusseldorf Heinrich-Heine-University DusseldorfMedical FacultyDivision of CardiologyPulmonology and Vascular MedicineDusseldorfGermany Neurosciences Critical Care Unit Addenbrooke's HospitalCambridgeUK Department of Intensive Care Hopital ErasmeUniversite Libre de Bruxelles(ULB)BrusselsBelgium Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti Fondazione IRCCS Ca'Granda-Ospedale

脓毒症是一种由感染引起的异质性疾病,感染触发了一系列复杂的局部或者全身的免疫炎症反应,引起多器官功能衰竭,发病率和病死率显著升高。由于至今仍然没有诊断脓毒症的金标准,所以脓毒症的临床诊断仍是一个难题。因此,脓毒症的临床诊... 详细信息

脓毒症是一种由感染引起的异质性疾病,感染触发了一系列复杂的局部或者全身的免疫炎症反应,引起多器官功能衰竭,发病率和病死率显著升高。由于至今仍然没有诊断脓毒症的金标准,所以脓毒症的临床诊断仍是一个难题。因此,脓毒症的临床诊断需要不断改变来满足临床和研究的要求。然而,尽管有许多新型的生物标记和筛选工具去预测脓毒症发生的风险,但是这些措施的诊断价值和有效性不足以让人满意,并且没有充分的证据去建议临床使用这些新技术。因此,脓毒症的临床诊断标准需要定期更新去适应不断产生的新证据。这篇综述旨在呈现当前脓毒症的诊断和早期识别方面的最新研究证据。临床运用不同的诊断方法的推荐意见依赖于推荐、评价、发展和评估分级体系(Grades of Recommendation Assessment,Development and Evaluation,GRADE),因为大部分的研究是观察性研究,并没有对这些方法进行可靠评估,采用的是两步推理方法。未来需要更多研究来确认或者反驳某一特殊的指标检测,同时应该直接采用相关病人的结果数据。

关键词：脓毒症早期识别诊断

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5位最棒的前童星

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海外英语 2003年第12期 9-页

作者： kim Morgan Faye

　　1. Drew Barrymore　　How could we not include our little Drew? Though now on top as one of America's sweethearts,her lineage1 of theatrical and cinematic royalty is the quintessence2 of the live fast, die young kiddo3. Thankfully, she lived."Little Girl Lost" is the title of her autobiography and boy was she ever.……

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青年人群单纯收缩期或舒张期高血压的心血管病风险

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中华高血压杂志 2020年第8期28卷 703-703页

作者：刘青(译) 刘莉(校) Lee H Yano Y Cho SMJ Park JH Park S Lloyd-Jones DM kim HC 不详

根据2017年美国心脏病学院/美国心脏协会高血压指南定义,在1级高血压青年人群中,关于单纯收缩期高血压(isolated systolic hypertension,ISH)、单纯舒张期高血压(isolated diastolic hypertension,IDH)或收缩期和舒张期高血压(systolic ... 详细信息

根据2017年美国心脏病学院/美国心脏协会高血压指南定义,在1级高血压青年人群中,关于单纯收缩期高血压(isolated systolic hypertension,ISH)、单纯舒张期高血压(isolated diastolic hypertension,IDH)或收缩期和舒张期高血压(systolic and diastolic hypertension,SDH)相关的健康预后知之甚少。方法:在全国健康筛查数据库中.

关键词：舒张期高血压美国心脏协会单纯收缩期高血压青年人群 hypertension 心血管病风险

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